ʻO ka hōʻailona nui no ka hoʻohana ʻana o Krestor ka hoʻonui ʻia ʻana o ka kolamu ma ka hihia o ka hypercholesterolemia, atherosclerosis a me nā ʻaoʻao ʻē aʻe o ka cardiovascular.
Hoʻolaha maʻalahi nā papa lāʻau e nā maʻi, nā hanana a pau ke loaʻa pinepine ʻole nā hopena. Inā pono, e kuhikuhi ka luna kuʻuna i nā synonyms (Rosuvastatin, Rosart, Mertinil) a i nā analogues (Atoris, Vasilip, Zokor). Hiki ke ʻike ma ka ʻike ʻike ʻike.
ʻO ka ʻike pili i ka lāʻau lapaʻau
ʻO ka mea hana i ka lāʻau lapaʻau ka hui lāʻau lapaʻau ʻo AstraZeneca UK Limited, aia i UK.
Hoʻokuʻu ʻia ʻo Crestor (inoa Latin - Crestor) i ka palapala papa no ka hoʻohana pono ʻana. Hiki i nā hewa ke kūlike - 5, 10, 20 a 40 mg o ka mea ikaika. ʻO ka pepa kāleka, hiki ke ʻike ʻia i nā kiʻi ma ka Pūnaewele, aia i ʻelua mau pōpoki o 14 mau papa.
Hoʻokahi papa papa me ka mea pahala rosuvastatin hoʻōla (rosuvastatin) a me nā mea he nui. Hana ʻia nā papa ʻula a i ʻole ka oval, ua hilinaʻi ʻia ko lākou kala ma ke ʻano - melemele (5 mg) a me ka pink (10, 20, 40 mg).
ʻO ka keʻa he hopena lipid-hoʻohaʻahaʻa. ʻO Rosuvastatin, e hoʻonui ana i ka nui o nā mea i hopu ai i ka ate, e hōʻemi i nā kiko o ka cholesterol "kino" (LDL a me VLDL) i ke koko. A ʻo ke kumu, ka haʻalele ʻana o ka dissimilation (catabolism) a me ke ʻano o ka hoʻōla LDL, ua hōʻemi ʻia ka hana ʻana o ka "maikaʻi" kolesterol.
No laila, hoʻokahi pule ma hope o ke kāhiko, he hōʻemi i ka nui o ka cholesterol, LDL, VLDL, triglycerides, etc. Loaʻa ka hopena kiʻekiʻe o ka hoʻohana ʻana i ka lāʻau ma hope o 14 mau lā.
Ma hope o ka lawe ʻana i nā papa, ua hōʻea ka ʻike o ka koina nui ma hope o 5 mau hola. Eia kekahi, hoʻopili maikaʻi ʻo rosuvastatin i nā protein protein.
Hoʻonohonoho ʻia ka hapa nui o ka māhele nui, ma ke ʻano he kānāwai, me nā kuʻekuʻe liʻiliʻi a me kahi liʻiliʻi me ka urine. ʻO ka hoʻohana lōʻihi ʻana i ka lāʻau lapaʻau no nā maʻi ʻoi e hiki ke hoʻopilikia i nā pākuʻi pharmacokinetic.
Nā hōʻailona a me nā contraindications no ke hoʻohana
Kūkū ke kauka i kahi lāʻau lapaʻau hypolipidemic no ka pale ʻana a me ka mālama ʻana i ka hypercholesterolemia homozygous, atherosclerosis.
Eia kekahi, ua hoʻohana ʻia ka lāʻau lapaʻau e mālama i nā pathologies cardiovascular, me ke ʻano o ka hōʻuluʻulu ʻana o nā hōʻuluʻulu paʻakikī o hypercholesterolemia.
ʻO nā ʻōkuhi no ka hoʻohana ʻana i kahi papa inoa o nā contraindications. Ke hilinaʻi nei lākou i ka nui o ka lāʻau.
Pāpā ʻia ka hoʻohana ʻana o Krestor 5.10.20 milligram i ka poʻe nāna:
- ka hoʻonui māla ʻana i nā ʻenehana i hana i ka ʻano hana;
- mai hōʻeha ʻia i nā maʻi pepeha koʻikoʻi, a me ka piʻi hoʻi o ka hana o nā transaminases hepatic;
- ma ka manawa like o ka hana maʻi cyclosporin;
- pilikia mai ka palaka ʻana;
- aia ka lolopa lolaka a lactase nele;
- ʻaʻole i hiki i ka makahiki 18;
- e loaʻa ana i ka myopathy (holomua neuromuscular pathology);
- hāpai a ʻeha paha.
Kahi ʻia ka mana o 40 milligrams i loko o nā poʻe e:
- Ininu i ka waiʻona.
- Hoʻokumu ʻia mai ka maʻi hepatic a i ʻole paha.
- Aia lākou i ke kūlana kiʻekiʻe o ka myopathy.
- Lawe i nā fibrates i ka paʻakikī.
- Ua hana hou ʻia i kēia wā.
- Lalau mai i na mea hooweliweli, epilepsy.
- E loaʻa i ka hypothyroidism.
- Loaʻa iā lākou kahi helu o ka electrolytes i ke koko.
- Loaʻa hou ʻia nā hōʻeha koʻikoʻi.
- Loaʻa mai hypotension arterial.
- Hoʻokomo ʻia me ka maʻi septic.
- Pilikia mai ka maʻi pālahalaha.
- ʻO Belong i ka lāhui Mongoloid.
ʻŌlelo pū ka papa ʻōlelo aʻo i ka poʻe kahiko (60 mau makahiki a ʻoi aʻe), ua kuhikuhi ʻia ka lāʻau lapaʻau me ka mālama nui loa.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
ʻAe nā mākua i ka lāʻau lapaʻau no ka ʻole o ka pāʻina - i ke kakahiaka a i ke ahiahi. ʻAʻole hiki ke ʻānai ʻia a hoʻokaʻawale ʻia nā papa, e holoi ʻia me ka wai liʻiliʻi.
Hoʻoholo ʻia ka nui a me ka lōʻihi o ke kauka ʻana e ke kauka, i ka nānā ʻana i nā mea like e like me ka nui o ka maʻi a me nā ʻano pilikino o ka mea maʻi.
Wahi a nā ʻōkuhi, ʻo ka make mua ka wai 5-10 milligrams. ʻO ke ala no ka mālama ʻana he 21 lā, ʻaʻole pono kahi hoʻomaha. Inā pono, he kuleana ke kauka e hoʻonui i ka nui o ka lāʻau.
Ua koi ikaika ʻia ʻoe e nānā i ka olakino o ka mea maʻi i nā lā mua, ka mea i hoʻololi wale iā Krestor 40 milligrams. Ma muli o ka hoʻohui i ke kino i ka mea hana, hiki i ka hoʻomohala ʻia o nā hōʻike ʻano maikaʻi ʻole.
No nā poʻe me kahi awelika o ka hiki ʻole o ka renal, ke kauka nei ke kauka i kahi ma mua o 5 mg i kēlā me kēia lā, hoʻonui pinepine ʻia i 40 mg.
Ma muli o ka nui o ka poʻe o ka lāhui Mongoloid he mau hiʻohiʻona o ka hana o ka ate, ka lawe ʻana iā Krestor 20 lāua ʻo 40 mg. ʻO ka maʻa mua he 5 mg, a laila e hoʻonui i ka 10 mg.
Ua hoʻohuli ʻia e kuhikuhi i nā mea hou aku ma mua o 20 mg i kēlā me kēia lā i nā mea maʻi e pilikia nei i ka myopathy.
Pono e mālama i ka laiki lipid ma ka wahi anu. Mai ʻae i ka pauka i hāʻule i loko o nā lima o nā keiki.
ʻO 3 ka manawa o ke ola ma hope, ma hope o kēia manawa, ua pāpā ʻia ke ka lāʻau lapaʻau.
Nā hopena ʻaoʻao a me ka overdose
I nā hihia maʻamau, i ka wā e hoʻohana ai iā Krestor, hiki paha ke hopena.
E like me ke kānāwai, ua hoʻokaʻawale maikaʻi ʻia ka lāʻau laʻa, a ma ka manawa o ka hoʻohana ʻana i nā ʻano nui, hiki ke loaʻa i nā hopena maikaʻi ke kūʻokoʻa ʻole e loaʻa ana ke kōkua olakino.
Aia nā ʻōlelo e hoʻohana ai i ka papa inoa inoa o nā hopena ʻaoʻao:
- maʻi kūlohelohe - urticaria, rashes ma ka ʻili, ka edema o Quincke;
- nā maʻi dyspeptic - kahi kīnā hemahema, nausea, luaʻi a luhi;
- hōʻino o ka ʻōnaehana o ka nerve - dizziness a me ke kaumaha ma ke poʻo;
- ka heleʻana o ka protein i ka urine, i kekahi manawa i ka hopena o kahi hana ʻole ʻole;
- nā ʻehaʻeha o ke aʻeha, i nā hihia hōʻemi, ka hanana nui o ka myopathy;
- ka hoʻomohala ʻana o ka non-insulin-hilinaʻi (type 2) diabetes mellitus;
- hepatic dysfunction, hoʻonui hana o ka hepatic transaminases.
Me kahi overdose o ka lāʻau lapaʻau, hoʻonui ka hopena ʻaoʻao. Hōʻike ʻia ia i ka pale hewa ʻana o ka hana o ke ʻano ponoʻī a me ka pale ʻana o nā pēpē a me nā ate.
ʻAʻohe mea antidote kikoʻī, ma kēia hihia ʻaʻole pono o ka hemodialysis. No ka hoʻopauʻana i ka overdose, hana ke ʻano hōʻailona maʻi.
Eia kekahi, pono ka mālama pono ʻana i nā enzyme o ka naʻau.
ʻO nā hōʻike ʻē aʻe ʻē aʻe
Ma ke ʻano o Krestor me kekahi mau pūʻulu o nā lāʻau lapaʻau ke alakaʻi i nā hopena i makemake ʻole ʻia. No laila, e hōʻike ka mea maʻi i kāna kauka e pili ana i nā maʻi āpau e pale ai i nā hopena maikaʻi ʻole mai ke kino.
Ke ʻōlelo nei nā ʻōlelo e pili ana i ka hui like ʻole o Krestor me Cyclosporin. ʻO ka hoʻohana ʻana i nā ʻaila lipid-hoʻohaʻahaʻa ʻē aʻe, no ka hoʻohālike, ʻo Hemifibrozil, e hoʻololi i ka plasma o ka waiwai o ka mea ikaika o rosuvastatin.
He kūpono ʻole ʻo Krestor me Warfarin a me nā lāʻau Kagonagonalona K, no ka mea e pili ana i ka index prothrombotic.
ʻAʻole ia e hāʻawi iā Krestor a me Ezetimibe i ka manawa like, no ka mea hiki ke hoʻonui i kēia i ka piʻi a me ka paʻakikī o nā hopena ʻaoʻao.
ʻO ka mea maʻi e hoʻoneʻe i ka hoʻomaka ʻana o ka myopathy, ʻaʻole pono e hoʻohana i ka hemofibrates, fibrates, nicotinic acid, a me ka gemfibrozil me ka rosuvastatin.
Eia kekahi, nā mea i hoʻopili ʻia e pili ana i ka ʻike e pili ana i ka launa ʻole i ka launa pū ʻia o nā antacids, contraceptives waha, inhibitor protease. Hoʻopau ka mea like i nā lāʻau lapaʻau e like me Erythromycin, Lopinavir a me Ritonavir.
I ka mālamaʻana i nā lipids kiʻekiʻe, keʻae ʻia ka hoʻohana ʻana i ka waiʻona.
ʻO ke kumukūʻai a me ka manaʻo noʻonoʻo
Hiki iā ʻoe ke kūʻai i ka lāʻau lapaʻau Krestor wale nō me kahi kaukaʻi a kauka. Eia kekahi, ʻoi aku ka uku o ke kauoha ma ka pūnaewele ma ka pūnaewele o ka luna alohilohi.
Kuhi ke kumukūʻai i ka nui o nā blisters a me nā helu. Hōʻike ʻia ka palena kumukūʻai ma lalo nei:
- 5mg (ʻAʻohe 28) kumukūʻai - 1835 mau rubles.
- Kumukūʻai Krestor 10mg - 2170 rubles.
- 20 mg - 4290 kahaha.
- 40 mg - 6550 kahaha.
No laila, ʻo ka mea i hoʻopili ʻia ai ʻo Krestor ka mea kūʻai ʻia, no laila, ʻaʻole kūpono no nā mea maʻi haʻahaʻa. ʻO kēia ka minus koʻikoʻi o ka lāʻau.
Mai ka manawa i kū mai ai ʻo Krestor ma ka mākeke kūʻai hale kūʻai ma ka lōʻihi o ka lōʻihi, ʻaʻole i nui nā loiloi e pili ana iā ia. Hoʻomaʻamaʻa ia i kēlā me kēia kanaka no ka mālama ʻana i ka hyperlipidemia, keu ma hope o ka hōʻeha a i ka ʻeha ʻana hoʻi.
Hoʻomaopopo kekahi mau mea kūʻai aku i nā hōʻeha a me nā pilikia hiamoe i ka wā e mālama ai. Mālama pono nā mea hōʻike i nā mea e pili ana i ke koko o nā poʻe maʻi, me ka helu o nā ʻalemona o ka ate.
Ma keʻano holoʻokoʻa, makemake nā kauka a me nā maʻi i ka hopena therapeutic o Crestor.
I ka manawa pinepine, ʻike ʻia nā loiloi kūpono e pili ana i ka lāʻau lapaʻau.
ʻLelo a me nā kikoʻi o ka lāʻau lapaʻau
Inā contesticated ʻo Krestor i ka mea maʻi, a he mau hopena paha, ke kauka nei ke kauka i kahi mea pono.
Hiki i kēia ke like me kahi kikoʻī, i ka hoʻonohonohoʻana i nā mea hoʻokahi a me nā mea hana like, a hui paha e loaʻa iā ia ka hopena therapeutic like ʻole, akā loaʻa nā mea kaha like.
I waena o nā hōʻailona ʻokoʻa, ʻoi loa ka maikaʻi a kaulana hoʻi.
- ʻO Mertenil kahi lāʻau lapaʻau haʻahaʻa loa (450 rubles no nā pākaʻi 30 no 5 mg), e hoʻemi ana i ka cholesterol i kahi kaono e hiki ai. Loaʻa ia nā hōʻailona like a me nā contraindications. Lawe ʻia ka mālama ʻana i nā mea maʻi ma ka hopena kiʻekiʻe o ka hoʻomohala ʻana i ka myopathy / rhabdomyolysis, hypothyroidism, a me ka maikaʻi ʻole o ka renal.
- ʻO Rosart kahi lāʻau lapaʻau kūpono ʻē aʻe no ka mea haʻahaʻa haʻahaʻa a me ka waena. I ka awelika, ʻo ka uku o ka pulu (No. 30 no 5 mg) ka 430 mau rubles.
- Rosuvastatin, ke ʻano inoa like pū me ka mea kanu ikaika. K kaulana i waena o nā mea maʻi, ʻoiai ke kumukūʻai o ka ʻeke pūpū (No. 30 no 5 mg) ka 340 mau rubles.
Hoʻohui ʻia nā pākuʻina kūpono:
- Loaʻa iā Vasilip kahi hopena lipid-hoʻohaʻahaʻa, ʻo kāna mea ikaika e simvastatin. Hoʻokumu ka mea hana i nā papa me kahi maʻi o 10.20 a 40 milligrams. ʻO ke kumu kūʻai o ka pauka (28 mau papa no ka 10 mg) he 250 rubles.
- Hoʻopili nā poʻe me nā atorvastatin i ka mea i hoʻonui ʻia, ka mea i hoʻonui i ka hana o nā ʻāpono LDL i loko o ka poupona a me nā ʻili extrahepatic. He nui nā contraindications: hypersensitivity o kēlā me kēia, nūʻai o nā leʻaleʻa, hoʻonui transaminases, lactation a me ka hapai. ʻO ke kumu kūʻai o Atoris (30 mau pākahi no 30 mg) he 330 mau rubles.
- Loaʻa iā Zokor i ka simvastatin, ka mea paʻa mai ka HMG-CoA reductase. ʻO nā mea hana nā USA a me ka Netherlands. He mau hōʻailona like ia a me nā contraindications e like me nā lāʻau lapaʻau ma mua, ʻoiai me ka wā ʻōpiopio. ʻO ke kumu kūʻai o ka pauka (28 mau papa no ka 10 mg) ʻo 385 mau rubles.
No laila, hiki iā ʻoe ke hoʻohālikelike i ka hopena therapeutic a me ke kumukūʻai o nā lāʻau, ke koho i ke koho ʻoi loa. ʻAʻole mākou e poina i ka pale a me ka mālama ʻana o ka atherosclerosis a me hypercholesterolemia, pono ʻoe e hana i ka hoʻomaʻamaʻa kino a hahai i kahi ʻai.
Hoʻokuʻu ka meaʻai kūikawā i ka ʻai ʻana o nā momona, nā pēpala, ka ʻūlū, nā meaʻai paʻakai, a me nā kīʻaha me kahi haʻahaʻa kolamu kiʻekiʻe. Ma waho o kēia mau māhele ʻelua, hiki ke hoʻomāino ʻia ka lāʻau lapaʻau.
Ua wehewehe ʻia nā statins ma nā kikoʻī i ke wikiō ma kēia ʻatikala.
