Ke lāʻau lapaʻau Diapiride: nā ʻōlelo no ka hoʻohana ʻana

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ʻO kahi Diapiride kahi lāʻau lapaʻau me ka hopena hypoglycemic lōʻihi. Aia ka lāʻau i ka nui o nā derivatives sulfonylurea.

Inoa Kūʻai ʻole honua

Nā kālā INN - Glimepiride.

ʻO kahi Diapiride kahi lāʻau lapaʻau me ka hopena hypoglycemic lōʻihi.

ATX

IU code ATX: A10VB12.

E hoʻokuʻu i nā palapala a me ka ʻano

Hana ʻia ka lāʻau lapaʻau i ke ʻano o nā papa me nā ʻano like ʻole o ka mea ikaika. I loko o kahi pahu kāleka he 30 mau papa i nā palaka. 1 papa pili iā 2, 3 a i ʻole 4 mg o ka glimepiride (mea ikaika). ʻO nā papa ʻaina me kahi dosage o 2 mg mau kukui he'ōmaʻomaʻo, 3 mg kukui ke kukui, 4 mg ʻolika ka aniani.

ʻO ka hoʻonohonoho ʻana o nā papa i loaʻa nā mea like loa.

  • lactose monohala;
  • mikulamulamina selulose;
  • sodium starch glycolate;
  • povidone;
  • ʻōmaʻomaʻa melemele;
  • magnesium stearate;
  • indigo carmine.

Loaʻa iā Glimepiride ka hopena hypoglycemic ma o ka hoʻoulu ʻana i ka hoʻokuʻu i ka insulin.

Ka hana lāʻau lapaʻau

Loaʻa iā Glimepiride ka hopena hypoglycemic ma o ka hoʻoulu ʻana i ka hoʻokuʻu i ka insulin. Hoʻopili ka mea hana i nā membrane o cells-cell o ka pancreas, e pani ana i nā kahe pāka. I ka hopena, ua lilo kēia mau sela i ka naʻauʻai i ka nui o ka kō i ke kō, a hoʻokuʻu ʻia i ka insulin a maʻalahi a me ka wikiwiki.

Aia kekahi i ka hoʻonui ʻia ʻana o ka hoʻoweliweli ʻana o nā ʻoli i ka insulin, a ua hoʻemi ʻia kona hoʻohana ʻana e ka ʻāpana o ke au. I ka manawa like, pale ʻia ka gluconeogenesis. Mālama ka lipid a me ka mākeke i nā molekiko hoʻokaʻawale ma muli o ka hoʻonui o ka nui o nā protein o ka halihali.

ʻO ka hana ikaika e hoʻemi ana i ka nui o ke kaumaha o ka maʻi oxidative ma ka hoʻouluʻana i ka hana o ka α-tocopherol a hoʻonui i ka hana o nā enzyme antioxidant.

Lapaʻau lāʻau

Ma hope o ka lawelawe waha, ua hoʻopili koke ʻia ka glimepiride i ka hoʻopili ʻana a komo i ke kahe koko. ʻO ka ʻai ʻana, ʻaʻole i hōʻemi i ka lawe ʻana o ka lāʻau. Ua hiki i kēia mea hoʻonaʻeha loa i kona kaila koko i loko o nā hola 2-2.5.

Ma hope o ka lawelawe waha, ua hoʻopili koke ʻia ka glimepiride i ka hoʻopili ʻana a komo i ke kahe koko.

Hōʻike ʻia ka Glimepiride e ka hoʻopiʻi maikaʻi ʻana i nā protein koko (99%). Lawe ʻia ka metabolism o ka lāʻauʻala ma ka nuku. ʻO nā metabolite ka hopena e hōʻike ʻia e nā pōpoki a me nā lau. Hoʻokuʻu ʻia ka lāʻau lapaʻau mai ke kino ma loko o nā hola 10-16. ʻOiai e lawe ana iā Diapiride, ʻaʻole i ʻike ʻia ka hōʻiliʻili o nā mea i loko o ke kino (ʻoiai me ka hoʻohana mau ʻana).

Nā hōʻailona no ka hoʻohana ʻana

Hoʻohana ʻia ka lāʻau lapaʻau e mālama i nā mea maʻi me ka diabetes mellitus type II. Hoʻonohonoho ʻia nā papa i ka hiki ʻole ke hoʻokaʻawale i ke kōpaʻa koko me ka hoʻohana ʻana i nā mea kūpono a me ka palaʻai ʻana.

Nā Hoʻohui

ʻAʻole pāpā ʻia ka lāʻau lapaʻau inā aia nā ʻano contraindications penei:

  1. Ke hoʻomanawanui pilikino ʻana i ka sulfonamides.
  2. Hypersensitivity i nā ʻāpana.
  3. Coma
  4. Ketoacidosis.
  5. ʻO nā ala paʻakikī o nā palu a me nā palaka paha.
  6. ʻAno maʻi type 1.
  7. ʻO ka wā hāpai a me ka lactation.
  8. Nā makahiki o nā keiki.

Me ka mālama pono

Ma lalo o ka mākaʻikaʻi paʻa ʻana o kahi kauka, hoʻohana ʻia ka lāʻau lapaʻau no ka hana wikiwiki, ka wai ʻawa, ke kuni, ke ʻōpala thyroid, ka lawa ʻole o ka adrenal a me nā maʻi kaumaha.

Ma hope o ka hoʻoili kino o ka hōʻeha ʻana, nā mea hōʻeha, ke kau ʻana, ʻōlelo ʻia nā mea maʻi e hoʻohuli i ka hoʻomehana insulin.

Pehea e lawe ai i ka diapiride?

Lawe ʻia ka lāʻau pono me ka wai liʻiliʻi. Hoʻomaopopo ʻia e hoʻohui i ka lawe ʻana i nā papa me ka meaʻai no ka pale ʻana o nā pono gastrointestinal.

Hoʻole ʻia ka lāʻau lapaʻau ma ka coma.
Ka pāpā ʻia i ka lāʻau lapaʻau ma mua o ka ketoacidosis.
ʻAʻole pāpā ʻia i ka lāʻau lapaʻau ma mua o nā hana koʻikoʻi o ka nui o nā moʻi a me nā pēpē.
Lā ʻia ka lāʻau lapaʻau ʻia ma ke alo o ke ʻano maʻi type 1.
Lā ʻia i ka lāʻau lapaʻau i ka wā hāpai.
Lā ʻia ka lāʻau lapaʻau i ka wā lactation.
Hōʻike ʻia ka lāʻau lapaʻau i ka wā kamaliʻi.

Me ka maʻi diabetes

No ka mālamaʻana i ka non-insulin-depend type type II mellitus, lawe ʻia kēia lāʻau lapaʻau i 1-2 mau manawa i ka lā. I ka hoʻomakaʻana o kēiaʻano, ʻo ka nui o nā pulu e 1 mg ma kahi o ka glimepiride. Inā lawa ka hana maʻamau i ka glucose i ke koko, a laila ʻaʻole hoʻonui ka nui o ka make.

Me ka loaʻa ʻole o ka hopena, hoʻonui ka lohi i ka 2, 3 a i ʻole 4 mg. ʻO ka palena ma waena o nā loli dosage e liʻiliʻi ma kahi o 7 mau lā. No kekahi manawa ua kuhikuhi ʻia nā mea maʻi 6 mg o ka glimepiride i kēlā me kēia lā (ʻokoʻa loa ka ʻele loa i kēlā me kēia lā).

Hiki i nā kauka ke kuhikuhi i ka hoʻokele ʻana o ka lāʻau lapaʻau me ka metformin a i ʻole insulin e hoʻokō i ka hopena kiʻekiʻe. ʻO ka lawe ʻana i kēia mau lāʻau hiki ke piʻi i ka hoʻonui mau ʻana o ka hiki ʻana i nā insulin. I kēia hihia, ua hoʻemi ʻia a emi ʻole ke ʻano o ke ʻano.

Nā hopena ʻokoʻa o Diapyrid

Ma ka ʻāpana o ka io o ka hihiʻo

I ka wā mālama, hiki ke hele ʻia kahi hana hoʻoweliweli ākea (hōʻemi i ka wa pōkole). ʻO ke kumu o kēia hopena hopena he hoʻololi i ke kō koko.

No ka mālamaʻana i ka non-insulin-depend type type II mellitus, lawe ʻia kēia lāʻau lapaʻau i 1-2 mau manawa i ka lā.

ʻŌpala Gastrointestinal

Ka hopena ma ka pale ʻana o ka huina:

  • ninaki a me ka luaʻi
  • nā ninia
  • ʻeha ka ʻōpū;
  • nā maʻi ate (hepatitis, hōʻoki ʻana o ka ate, a me nā mea).

Hematopoietic mau hui

ʻO nā hopena ʻaoʻao mai ka ʻōnaehana hematopoietic:

  • thrombocytopenia;
  • leukopenia;
  • anemia
  • granulocytopenia;
  • erythrocytopenia;
  • agranulocytosis;
  • pancytopenia.
I ka wā o ka lawe ʻana i ka lāʻau lapaʻau, hiki paha i ka nausea.
I ka manawa o ka lawe ʻana i ka lāʻau lapaʻau, hiki paha i ka luaʻi.
I ka wā o ka lawe ʻana i ka lāʻau lapaʻau, ʻike paha nā maʻi.
I ka wā o ka lawe ʻana i ka lāʻau lapaʻau, ʻike ʻia ka ʻeha o ka ʻōpū.
I ka wā o ka lawe ʻana i ka lāʻau lapaʻau, ʻike ʻia nā maʻi hepatitis.
I ka wā o ka lawe ʻana i ka lāʻau lapaʻau, ʻike ʻia nā hina ole.
I ka wā o ka lawe ʻana i ka lāʻau lapaʻau, hiki paha i kahi anemia.

Pūnaehana pīhoihoi waena

Mai ka ʻaoʻao o ka ʻōnaehana hoʻonāukiuki i ʻike ʻia:

  • lie kanikela
  • ʻʻAla
  • pupule o ka ike;
  • ʻōpala
  • luhi;
  • nā kūlana kaumaha;
  • ka hoʻemi ʻana o nā hopena psychomotor;
  • haunaele ʻōlelo;
  • nunui o nā wāwae;
  • nahoa.

Mai ka ʻaoʻao o ka metabolism

Hōʻike ka hopena maikaʻi ʻole i ka hana metabolism e ka hypoglycemia.

Allergies

I ka wā o ka hoʻokele ʻana, hiki i nā hopena maʻi:

  • ʻili;
  • urticaria;
  • ʻohiʻala
  • maʻi vasculitis.
    No ka manawa o ka lapaʻau ʻana me ka lāʻau lapaʻau mai ka pūnaehana poepoe ma waena, hiki paha ke poʻo.
    No ka manawa o ka mālama ʻana me ka lāʻau lapaʻau mai ka pūnaehana poepoe ma waena, hiki ke hūnā.
    No ka manawa o ka mālamaʻana me ka lāʻau lapaʻau mai ka ʻaoʻao o ka ʻōnaehana nerve waena, e ʻike ʻia paha ka hilahila.
    No ka manawa o ka mālama ʻana me ka lāʻau lapaʻau mai ka pūnaehana poʻokela sentral, hiki mai paha ka insomnia.
    No ka manawa o ka mālama ʻana me ka lāʻau lapaʻau mai ka pūnaehana poʻokela o loko, hiki mai paha ka luhi.
    I ka wā o ka mālama ʻana me ka lāʻau lapaʻau mai ka pūnaehana mikina kikowaena, hiki mai paha nā kūlana kaumaha.
    No ka manawa o ka mālama ʻana me ka lāʻau lapaʻau mai ka pūnaehana mikipū kikowaena, hiki mai paha nā hoʻokolokolo.

Hoʻopilikia i ka hiki ke mālama i nā mīkini

Hiki i ka lāʻau lapaʻau ke hōʻemi i ka wikiwiki o nā hopena psychomotor a hoʻoiho i ka dizziness. I ka hoʻomaka ʻana o ka hoʻōla, a me ka hoʻoponopono ʻana i nā dosis, ʻaʻole i kuhikuhi ʻia e hoʻokele i nā kaʻa a hoʻokō i nā hana ʻē aʻe e koi ai i ka nui o ka lono.

Nā ʻōlelo kikoʻī

Inā emi ka pae o ka glucose i ke koko mai ka laʻa haʻahaʻa haʻahaʻa loa i kēlā me kēia lā (1 mg o glimepiride), pono ia e hōʻoki pono i ka hoʻohana ʻana i ka lāʻau. Hiki ke hoʻokō i nā hopena hypoglycemic ma kēia hihia me ka hoʻohana ʻana i kahi lāʻau lapaʻau (me ka hoʻohana ʻole o nā lāʻau).

I ka wā o ka mālama ʻana, pono ʻoe e nānā i ke kaila o ke koko, ka hemoglobin glycosylated, me ka ʻūlū hoʻi, nā aʻa koko keʻokeʻo a me nā platelets i ke koko.

Hoʻohana i ka wā kahiko

Hāʻawi ʻia ka mea hana no ka poʻe maʻi o nā ʻokoʻa makahiki, me kaʻole o nā keiki. Akā hiki i nā poʻe kahiko me ka hoʻohana mau loa i nā lāʻau hoʻomohala e ulu i ka hypoglycemia. I mea e pale aku ai i kēia kulekele, kuhikuhi ke kauka i nā mea maʻi maʻi makua i ka meaʻai kūikawā a me nā helu haʻahaʻa o ka lāʻau (inā hiki).

Koha i na keiki

Hoʻohana ʻia ka lāʻau lapaʻau e hoʻohana ʻia ma hope o 18 mau makahiki.

Hoʻohana i ka wā hāpai a me ka lactation

I ka wā hāpai a me ka lactation, lawe ʻia i kēia lāʻau lapaʻau a contraindicated.

Inā emi ka pae o ka glucose i ke koko mai ka laʻa haʻahaʻa haʻahaʻa loa i kēlā me kēia lā (1 mg o glimepiride), pono ia e hōʻoki pono i ka hoʻohana ʻana i ka lāʻau.

Ke noi no ka hana renal haukapole

I nā maʻi koʻikoʻi oi, ʻaʻole kau ʻia kekahi lāʻau lapaʻau. Hoʻololi ʻia kēlā mau mea maʻi i ka haukapila insulin. Ma ka hoʻomaka mua o ka hiki ʻole o ka renal, hiki i ka hoʻohana ʻana i nā papa ma lalo o ka mākaʻikaʻi koʻikoʻi o kahi kauka.

Hoʻohana no ka hana lawelawe lēwa

ʻO nā maʻi ākea o ka puʻukū he mau contraindications i ka hoʻohana ʻana o ka lāʻau lapaʻau. I nā maʻi o ka hōʻeha haʻahaʻa a hōʻemi paha, hiki i kāna hoʻokele ma nā haʻahaʻa haʻahaʻa. Pono ka terapi e ka neʻe ʻana o ka ate.

Ka huhū o Diapiride

ʻO ke kaila o ka lāʻau lapaʻau ka alakaʻi i ke ʻano o nā hopena hypoglycemic (kahi pākeke ikaika i ke kōhi koko). I kēia hihia, hōʻeha ka mea maʻi i ka palupalu, ke kaumaha, mau maʻi kaumaha. Hiki paha ke nalowale. No ka hoʻopau ʻana i nā hōʻailona o kahi overdose, hele lākou i ka maʻi hōʻailona.

ʻO ke kaila o ka lāʻau lapaʻau ka alakaʻi i ke ʻano o nā hopena hypoglycemic (kahi pākeke ikaika i ke kōhi koko).

Hoʻopili pū me nā lāʻau ʻē aʻe

Pono ka lāʻau e hoʻokaʻawale me ka makaʻala e hui pū ai me nā lāʻau lapaʻau e like me:

  1. Fluconazole
  2. Phenylbutazone
  3. ʻAsapropazone.
  4. Sulfinpyrazone.
  5. Oxyphenbutazone.
  6. Pentoxifylline.
  7. Tritokvalin.
  8. Nā Disopyramides.
  9. Fenfluramine.
  10. Probenecid.
  11. Anticoagulants mai ka huimarahi.
  12. Nā Salicylates.
  13. Kekahi antidepressants (MAO inhibitors).
  14. Hoʻopuka ʻana.
  15. Hoʻolālā.
  16. Cyclophosphamide.
  17. Feniramidol.
  18. Ifosfamide.
  19. ʻO Miconazole
  20. Nā lāʻau Tetracycline a me quinolone.
  21. ʻO nā lāʻau lapaʻau hypoglycemic ʻē aʻe.
  22. ʻO nā mea maʻi anabolic.
  23. ACE paleai.
  24. PASK (para-aminosalicylic acid).

ʻO ka hoʻohaʻahaʻa i ka hopena o ka lāʻau e mālama ʻia ana i ka wā e lawe pū ʻia me Phenothiazine a me nā mea waiwai.

Me ka hoʻohana like ʻana o kēia mau kālā, ua hoʻonui ʻia ka hopena hypoglycemic Diapiride. ʻO ka hoʻohaʻahaʻa ʻana i ka hopena o ka lāʻau lapaʻau e nānā ana i ka wā e lawe pū pū me ka Phenothiazine a me nā mea waiwai, estrogens a me progestogens, glucagon, ka waikiko nikotinic, corticosteroids, barbiturates, Phenytoin, Acetazolamide, diuretics a me nā lāʻau lapaʻau no ka mālama ʻana i ka gland thyroid.

Hoʻolaha ka waipuna

ʻO ka lāʻau lapaʻau ka hoʻoili haʻahaʻa a me ka ethanol. Hiki i nā mea inu wai ke hoʻonui a hoʻoemi i ka hopena therapeutic o Diapiride.

Nā kuʻina

Aia nā ʻano like o ka lāʻau lapaʻau:

  1. Gliclazide.
  2. Maninil.
  3. Diabeton.
  4. Holaʻula.
  5. Kuiluna.
ʻO Glimepiride i ka mālamaʻana i ka maʻi maʻi
Nā huahana Kūleʻa Hypoglycemia maikaʻi
ʻO ka hoʻāʻo ʻia i ka wai maʻi diabetes
Maninil a Diabeton paha: ʻoi aku ka maikaʻi no ka maʻi maʻi (hoʻohālikelike a me nā hiʻohiʻona)

Waihue huaʻōlelo waiho nā huaʻōlelo

Hiki iaʻu ke kūʻai me ka loaʻa ʻole o ka hōʻailona?

Hoʻokuʻu ʻia ka lāʻau lapaʻau e ka lāʻau lapaʻau.

Kūʻai

ʻO ke kumukūʻai o Diapiride i loko o nā lāʻau lapaʻau e pili ana i ka 110 a 270 rubles, e pili ana i ka helu o ka mea e ʻike mau ai.

Ke waiho nei i nā kūlana no ka lāʻau lapaʻau

E mālama i nā papa i kahi maloʻo a pouli hoʻi mai kahi hiki ʻole o nā keiki, i ke ana ʻana a hiki i + 25 ° C.

ʻO ka lā kau

ʻO 2 mau makahiki kahi ola.

Mea hana

Mea Hana PJSC "Farmak" (Ukraine).

Hoike Mai

Lyudmila, 44 makahiki, Izhevsk.

Ua hoʻomaka wau e hoʻohana i kēia lāʻau lapaʻau e like me ka mea i kuhikuhi ʻia e ke kauka e hōʻemi i ke kō koko. Pono ka lāʻau lapaʻau a nani kūpono. Kōkua ia i ka mālama i ke kō.

Alexey, 56 makahiki, Moscow.

Ua maʻi wau i ka maʻi diabetes type 2 no nā makahiki he 5. Lawe au i kēia mau peni ma ka palena haʻahaʻa. Me ka hoʻohana maʻamau, paʻa ka pae hāwau o ke koko. ʻAʻole nā ​​hopena hopena. Akā hoʻāʻo wau e hoʻohui i ka lāʻau lapaʻau me ka meaʻai e pale ai i kahi kao haʻalulu i ka kō.

Anna, 39 makahiki, Voronezh.

Ua noi ʻia he endocrinologist e lawe i kēia lāʻau lapaʻau antidiabetic. ʻAeʻoluʻu wau i ka lāʻau lapaʻau, ʻaʻole wauʻike i kekahi ʻano ʻino. Ua kūpono maoli kāna kumukūʻai. Aia ka palena o ke kō i loko o nā palena maʻamau. Ke manaʻo nei wau!

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