Kūkulu ʻia ka hopena o Tritace Plus ma muli o nā hopena o ka hipa ramipril a me hydrochlorothiazide. ʻO ia mau mea ʻelua e pale i ka hoʻololi o ka angiotensin I ke ʻano o ka angiotensin II, a laila e loaʻa ai ka hopena antihypertensive. I kēia hihia, ʻaʻole hiki i nā lāʻau lapaʻau ke kūʻai aku i nā ʻoihana maʻi ma ke ʻano he monotherapy. Loaʻa i nā mea maʻi ka lawehala hypotensive ma ke ʻano o ka mālama paʻakikī i ka hypertension arterial e hoʻokō i nā pae kūloko o ke kahe koko.
Inoa Kūʻai ʻole honua
ʻO Hydrochlorothiazide + Ramipril.
ATX
C09BA05.
Kūkulu ʻia ka hopena o Tritace Plus ma muli o nā hopena o ka hipa ramipril a me hydrochlorothiazide.
E hoʻokuʻu i nā palapala a me ka ʻano
Loaʻa ka lāʻau lapaʻau i kahi palapala papa. Hoʻomoʻa ka 1 papa i nā pūhui hoʻoikaika 2 - ramipril a me hydrochlorothiazide.
| Nā ʻāpana hoʻoikaika | ʻO nā hui hiki, mg | |||
| ʻO Ramipril | 12,5 | 12,5 | 25 | 25 |
| ʻO ke Kahuaʻo | 5 | 10 | 5 | 10 |
| Nā peni kala | ʻākala | ʻōmaʻomaʻo | keʻokeʻo | ʻākala |
E hoʻomaʻamaʻa i nā hiʻohiʻona pharmacokinetic, hoʻohana ʻia nā mea hoʻohui aʻe:
- sodium stearyl fumarate;
- ka hāleʻa hao, ka mea e hāʻawi i nā papa i kahi waiho pālua e like me ka neʻe o nā mea hoʻoikaika;
- keʻa palaoa gelatinized;
- mikulamulamina selulose;
- hoʻohuʻihuʻi.
ʻO nā papa papa liʻiliʻi, me ka laina hoʻokaʻawale i nā ʻaoʻao ʻelua.
Lele maāka lāʻau i kauoha ʻia ma ka hana ʻoi me ka maʻi monotherapy.
Ka hana lāʻau lapaʻau
Hoʻohui ʻo Tritace i kahi ngiotensin e hoʻohuli ana i ka enzyme (ACE) inhibitor - ramipril, a me kahi thaizide diuretic hydrochlorothiazide. ʻO ka hui pū ʻana o nā hana ikaika he hopena antihypertensive ikaika. ʻAi aku ka blocker ACE i ka hoʻokumu ʻana o ka angiotensin II, kahi e pono ai e hōʻemi i nā iʻalima palupalu o ka votone endothelium.
Ke pale nei ʻo Ramipril i ka hanana ʻana o kahi hopena vasoconstrictor a pale i ka wāwahi o ka bradykinin, kahi waiwai no ka hoʻonui ʻana i nā kahe koko. Hoʻonui ka Hydrochlorothiazide i ka vasodilation, ma muli o kahi e hoʻonui nui aku ai nā moku. He mea nui ia e mālama i kahi kaila maʻamau o ka neʻe i ke koko i mea e pale ai i ka hoʻomohala ʻana o ka bradycardia a me ka hypotension arterial.
ʻO ka hopena therapeutic kiʻekiʻe loa e nānā ʻia i nā hola 3-6 ma hope o ka noi a hoʻomau i hoʻokahi lā. Loaʻa ka hopena diuretic o ka diuretic thiazide no 6-12 mau hola.
Lapaʻau lāʻau
Ua hoʻopili koke ʻia ʻo Ramipril a me hydrochlorothiazide i ka nui jejunum proximal, mai kahi a lākou e pā ai i ke kaila o ka systemic. ʻO ka bioavailability o hydrochlorothiazide ʻo 70%. I loko o ke koko, hiki i nā mea hoʻomehana kemika a hiki i kahi nui o ke koena i loko o 2-4 mau hola. Loaʻa iā Ramipril ka palena nui o ka hoʻopili ʻana i ka protein plasma - 73%, aʻo ka 40% o ka hydrochlorothiazide wale nō ka paʻakikī me ka albumin.
ʻO ka hapalua o nā ola o nā ʻāpana ʻelua i hiki i ka hola 5-6. ʻO Ramipril he 60% excreted i hui pū me ka urine. Hāʻawi ka Hydrochlorothiazide i ke kino i kāna kumu mua e ka 95% ma o ka pūpū i loko o 24 mau hola.
Nā hōʻailona no ka hoʻohana ʻana
Pono ka lāʻau pono e hoʻohaʻahaʻa i ke koko kiʻekiʻe.
Pono ka lāʻau pono e hoʻohaʻahaʻa i ke koko kiʻekiʻe.
Nā Hoʻohui
Hoʻokomo ʻia ka lāʻau i ka poʻe me:
- hypersensitivity i ka hydrochlorothiazide, ramipril a me nā mea waiwai'ē aʻe o Tritace;
- predisposition i ka hoʻolālā ʻana o ka Quincke edema;
- uha hooikaika kino;
- nā hoʻololi i nā electrolytes plasma: pālima, magnesium, calcium;
- maʻi ʻeha nui;
- hypotension koʻikoʻi.
Me ka mālama pono
Pono e kāohi i ka maikaʻi o ka mālama nui i ka wā o ka lāʻau lapaʻau i loko o ke alo o nā papa kuhikuhi:
- nāʻeha kaumaha o ka naʻau;
- nā maʻi i ka ventricle hema, hōʻike ʻia e nā loli hypertrophic;
- stenosis o nā moku nui, cerebral vessel, coronary a renal arteries paha;
- wai-hoʻoliʻelima metabolism;
- me ka hana o creinine o 30-60 ml / min;
- Hoʻoulu hou ʻia ma hope o kahi hoʻololi o ke keiki;
- maʻi ate
- poino ka pili pili - scleroderma, lupus erythematosus;
- ka loko o ka hoʻopulapula cerebral.
ʻO nā mea maʻi i lawe ma mua i nā diuretics e pono ke kaohi i ke ʻano o ka palaki ʻana o ka wai-paʻakai.
Pehea e lawe ai iā Tritace Plus
ʻAʻole kuhikuhi ʻia ka lāʻau lapaʻau ma kahi o ka lāʻau antihypertensive mua. Kuhi ʻia nā papa no ka hoʻohana waha. Ke inu ʻia ka lāʻau lapaʻau i ke kakahiaka. Hoʻoholo ʻia ka pākēneka e kekahi kauka lāʻau olakino ma muli o nā kuhikuhi o ke kahe koko (BP) a me ka nui o ka hypertension.
ʻO ka maʻi maʻamau ma ka hoʻomaka ʻana o ka lāʻau lapaʻau, ʻo 2.5 mg o ka ramipril i hui pū me ka 12.5 mg o ka hydrochlorothiazide. Me ka hoʻomanawanui maikaʻi, e hoʻonui i ka hopena hypotensive, hiki ke hoʻonui ʻia ka nui ma hope o nā hebedoma 2-3.
Me ka maʻi diabetes
Hiki i ka lāʻau lapaʻau ke alakaʻi i ka hypoglycemia me ka hoʻohana ʻana i nā lāʻau hypoglycemic a i ʻole insulin, no laila, i ka wā o ka mālama ʻana me ka lāʻau antihypertensive, pono ia e hoʻoponopono i ka hoʻowalewale o ka lāʻau antidiabetic. ʻO nā maʻi me ka maʻi maʻi e hoʻomau mau i ka pae o ko lākou koko koko.
Nā hopena ʻaoʻao o Tritace Plus
I ka nui o nā hihia, ʻaʻole pololei ka hemahema o Tritace i ka ʻeha a me ka hiolo.
ʻŌpala Gastrointestinal
Hōʻike ʻia nā maʻi pālahalaha huehue e ka hoʻomohala ʻana o nā huehue, a me ke ʻano o gingivitis, luaʻi i nā ʻalohilohi, a me ka constipation. Loaʻa paha ke hoʻomohala ʻana o ka gastritis, hōʻeha i ka ʻōpū.
Me nā maʻi gastrointestinal, hiki i ka gastritis ke ulu ma kahi ʻaoʻao.
Hematopoietic mau hui
Me ka hoʻohaʻahaʻa ʻana i ka hematopoiesis pumehana o ka iwi, ua emi ka nui o nā ʻōpū koko.
Pūnaehana pīhoihoi waena
Me ka nalowale o ka mālama naʻau psycho-emosyonal, loaʻa i ka mea maʻi ke kaumaha, kaumaha, a me ka hiamoe. E kū'ē i ke kua o nā kaumaha o ka wahina, aia ka nalowale o ka orientation i ka nui, kahi ʻeha, ka puʻuwai wela, hoʻolilo a i ʻole ka ʻeha hoʻoweliweli.
Mai ka pūnaehana urinary
Malia paha he hoʻonui i ka nui o nā urine i hoʻokuʻu ʻia a me ka hoʻomohala ʻana o ka hana ʻole o ka aʻalopona hemahema.
Mai ka papa huhū
I ka nui o nā hihia, ma muli o ka hoʻonui ʻana o ka nui o ka bradykinin, hiki i ka ʻōpala maloʻo ke ulu, ma kekahi mau mea maʻi - ʻoi a me ka ʻāʻī o ka sinus.
Ma ka ʻāpana o ka ʻili
Aia kahi hopena o ka hoʻomohalaʻana i ka angioedema, kahi hiki ke alakaʻi i ka asphyxia i kekahi mau hihia. ʻO nā hōʻailona like-psoriasis, hoʻonui nui loa, nā pulupulu, ʻeha a me ka erythema o nā ʻano etiologies like ʻole.
Ma muli o ka lawe ʻana i ka lāʻau lapaʻau, hiki i ka erythema o nā ʻano etiologies like ʻole.
Mai ka pūnaehana genitourinary
I nā kāne, hiki ke hoʻohaʻahaʻa i ka neʻe a me ka hoʻonui ʻana i nā kōmela manu.
Mai ka pūnaehana cardiovascular
ʻOi paha he hāʻule o ka hoʻokahe koko, thrombosis ma muli o ka hiʻona, stenosis o nā kīʻaha nui, pale ʻana i ka kahe koko, ka ʻaʻī o ka pā vascular a me ka maʻi Raynaud.
ʻŌnaehana Endocrine
Hiki i ke ʻano he hoʻonui i ka hana o ka hormone antidiuretic.
Ma ka ʻāpana o ka ate a me ka pāpaʻi biliary
I nā hihia kūʻokoʻa wale nō, ulu ka maʻi cytolytic o ka ate me ka hopena e hiki ai i ka hopena hōʻeha. Aia ka hoʻonuiʻana o ka pae o ka bilirubin i loko o ke koko a me ka loaʻaʻana o ka cholecystitis calculous.
Allergies
Hōʻike ka maʻi maʻi maʻi maʻi e ka hiʻohiʻona o nā hopena ʻili.
Hōʻike ka maʻi maʻi maʻi maʻi e ka hiʻohiʻona o nā hopena ʻili.
Mai ka ʻōnaehana musculoskeletal a me nā ʻaoʻao pili
Hiki i ke kanaka ke hōʻeha i ka ʻeha a me ka nāwaliwali o nā ʻili.
Mai ka ʻaoʻao o ka metabolism
I nā kūlana kūikawā, aia ka emi ʻana o ke kāhea ʻana o ke kiko i ka glucose, ma muli o ke ʻano o ka hoʻonui ʻana o ke kō koko. I ka haʻaleleʻana o ka metabolism holoʻokoʻa, e hoʻonui ka nui o ka urea i ka plasma koko, hoʻonui i ka gout a me nā anorexia. I nā pilikia pinepine, ulu nā hypokalemia a me ka metabolic acidosis.
Mai ka pā kūlohelohe
ʻOi paha ka hoʻomohala ʻana o nā hopena anaphylactic i pili me ka hoʻonui i ka ʻumiʻumi o nā antibodies antinuclear. Hiki i ka Tritace ke hoʻonāukiuki i ka angededema o ka maka, ka puʻupuʻu liʻiliʻi, nā wāwae a me ka alelo.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
Ma muli o ka emi ʻana o ka ʻike maka a me ka nalowale o ka ʻike, pono e makaʻala ka mea maʻi i ka wā e hoʻolalelale ana i nā mea paʻakikī a i ʻole nā kaʻaahi e koi ai i ka wikiwiki o ka hopena psychomotor a me ka piʻi nui ʻana.
Ma muli o ka emi ʻana o ke aniani a me ka nalowale o ka ʻike, pono ka mea maʻi e makaʻala i ka wā e hoʻokele ana i nā ʻiliahi a i ʻole nā kaʻa.
Nā ʻōlelo kikoʻī
Ma mua o kahi lilo o kahi mea maʻi i hoʻolālā ʻia, pono e hōʻike i ka ʻoihana lapaʻau a me ka mea hana hakahaka ma ke ʻano e pili ana i ka mālama ʻana me kahi inhibitor ACE. Pono kēia e pale i kahi hāʻule o ke koko i ka wā o ka hana.
Hoʻohana i ka wā hāpai a me ka lactation
Ma muli o nā hopena teratogenic a me nā hopena fetotoxic, ʻaʻole i kuhikuhi ʻia ka lāʻau lapaʻau no nā wahine hāpai. Aia ke komo hewa o ka neʻeʻana o ka intrauterine i loko o ka pūpū.
I ka wā mālama, pono ʻoe e hooki i ka hana umauma.
Hoʻohui Tritace Plus no nā keiki
Ma muli o ka hapa ʻole o nā data i ka hopena o Tritace i ke kino o ke kanaka i ka manawa hoʻomohala, ua contraindicated ka lāʻau i nā keiki ma lalo o ka makahiki 18.
Hoʻohana i ka wā kahiko
ʻAʻole pono nā poʻe kahiko e hana i nā loli i ka ʻano hoʻohālike.
ʻAʻole pono nā poʻe kahiko e hana i nā loli i ka ʻano hoʻohālike.
Ke noi no ka hana renal haukapole
ʻO ka poʻe maʻi e hōʻeha nei i ka maʻi o ke kino e mālama ai i ka hana hana a nā mea kino i ka wā o ka mālama ʻana.
Hoʻohana no ka hana lawelawe lēwa
Lā ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana e nā kānaka me ka nū lūlū.
Ka palena o Tritace Plus
Hōʻike ka kiʻi o ke kikowaena o kahi overdose iā ia iho i ka hōʻino ʻia o kahi mea hypotensive a hoʻohālikelike ʻia e ke ʻano o nā hōʻailona penei:
- ka polyuria, i nā mea maʻi me ka adenoma prostatic benign a i ʻole nā mea i hoʻopuka i ka maʻi urine e hoʻonāukiuki i ka hoʻokumu ʻana o ka stagnation o ka urination me ka haʻalele ʻana o kahi ʻāpana;
- bradycardia, arrhythmia;
- vasodilation peripheral;
- ka haʻalele ʻana o ka metabol-electrolyte metabolism;
- hilahila a me ka nalowale o ka ike ana me ka hoouluia o ka coma;
- nā wahī pilipila;
- pepelu kahi pōʻeha wahī.
Inā emi ma lalo o 30-90 mau minuke mai ka wā i lawe ʻia aku ai ka paila, a laila pono ʻia ka mea i hōʻuluʻulu i ka luaʻi ʻana a hoʻomoʻa i ka ʻōpū. Ma hope o ke kaʻina hana, pono ka mea maʻi e lawe i kahi adsorbent e hoʻolohi i ka lilo ʻana o nā mea ikaika. Me ka bradycardia koʻikoʻi, pono ia e hoʻopuka i ka intravenously 1-2 mg o adrenaline a hoʻonohonoho i kahi pacemaker pōkole. I ka hihia o kahi overdose, pono ia e kāohi i ka pae serum creatinine a me ke koko o ka wā i ka wā hōʻailona.
Me kahi overdose o ka lālani, ʻike ʻia nā ʻūhā o nā iwi.
Hoʻopili pū me nā lāʻau ʻē aʻe
Me ka hoʻomohala pinepine ʻana o Tritace me nā thiazides, hiki i ka nui o ke kolamu o ka kolamu ma ka serum koko.
Hoʻohui hui like ʻole
Pono ka lāʻau lapaʻau e pili ana me ka hoʻohana 'ana i ka aliskiren a me ka angiotensin II antagonist receptor. I ka hopena hope loa, ua hoʻonele ʻia ka hoʻomalu ma nā maʻi me ka polyneuropathy maʻi maʻi. ʻAʻole i kuhikuhi ʻia ʻo Aliskiren no ke hoʻololi ʻana i ke ake o ka pilikia nui ʻole.
ʻAʻole i hāʻawi ʻia
ʻAʻole e kuhikuhi ʻia i kahi hui antihypertensive hui pū me nā lāʻau hiamoe, lithium salts, tacrolimus me sulfamethoxazole.
ʻO nā hui e koi ana i ka mālama
Pono e nānā i nā kaulike palekana i nā ʻōhua like:
- tricyclic antidepressants;
- nā lāʻau lapaʻau antihypertensive ʻē aʻe;
- barvaluric acid derivatives;
- nā kālā kālā ma ka anesthesia aoao;
- kahi pāʻina sodium klorida;
- nā lāʻau lapaʻau diuretic;
- nā vasopressor sympathomimetics;
- allopurinol, nā mānoʻi immunomodulatory, glucocorticosteroids, cytostatics;
- estramustine, heparin, vildagliptin;
- nā mea lawelawe hypoglycemic.
I ka wā mālama, pono e hoʻohana pono nā mākaukau e pili ana i ka ethanol.
Pono e ho'ōla i ka lawe ʻana i ka ethanol.
Hoʻolaha ka waipuna
I ka wā mālama, pono e hoʻohana pono nā mākaukau e pili ana i ka ethanol. Ke lawe nei i ke Tritace me ka ethanol i mea like, aia paha kahi hopena o ka hoʻokupu.
Nā kuʻina
Ke lawe ʻia nei ka loli i kekahi lāʻau lapaʻau antihypertensive ma lalo o ka mākaʻi ʻana o ke kauka, nāna e kuhikuhi i kekahi o nā lāʻau lapaʻau e like me ke kahuli hou ʻana:
- Hartil-D;
- Amprilan NL;
- Amprilan ND;
- Wazolong H;
- Ramazid H.
Loaʻa nā maʻalahi i nā aniani i ka palena kumukūʻai - 210-358 rubles.
Waihue huaʻōlelo waiho nā huaʻōlelo
I kūʻai aku i nā kumu olakino.
Hiki iaʻu ke kūʻai me ke kī ʻole
Hiki i ka lāʻau lapaʻau ke kumu i ka hypthension orthostatic inā hoʻohana pono ʻole. No ka palekana o nā maʻi i nā lāʻau lapaʻau, hiki ke kūʻai wale ʻia ka lāʻau lapaʻau me kahi palapala hoʻolālā.
Kumukūʻai ma Tritac Plus
ʻO ke kumukūʻai maʻamau no nā papa he 5 mg ʻo 954-1212 rubles, me kahi paona o 10 mg - 1537 rubles.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Hiki ke mālama ʻia nā papa i ka mahana ma + 8 ... + 30 ° C ma kahi wahi i kaawale mai ka hana o ka lā.
ʻO ka lā kau
3 mau makahiki
Mea hana
Sanofi Aventis, Italia.
Hōʻikeʻike Tritac Plus
ʻO nā loiloi maikaʻi e pili ana i ka lāʻau lapaʻau e hōʻike ana ua hoʻokumu ke lāʻau iā ia iho i ka mākeke lāʻau lapaʻau.
Kauka
Svetlana Gorbacheva, cardiologist, Ryazan
He mea lawelawe e pili ana ka hydrochlorothiazide. Hoʻonui ka lāʻau i ka hopena antihypertensive. Ke kuhikuhi nei wau i ka lāʻau lapaʻau i kaʻu mau mea maʻi wale nō me ka hypertension arterial no hoʻokahi ʻano maʻi pākahi i kēlā me kēia lā. ʻO ka lōʻihi o ka lāʻau lapaʻau he kū hoʻokahi no kēlā me kēia maʻi. ʻAʻole i ʻike ʻia nā hopena ʻaoʻao. ʻAʻole ʻae ʻia ka poʻe me ka maʻi hōʻeha kino e lawe i ka lāʻau lapaʻau.
ʻO nā maʻi maʻi
Alexey Lebedev, 30 mau makahiki, ʻo Yaroslavl
Hoʻomaka ka makuahine i ka hōʻike ʻana i ka hypertension me ka makahiki. Ma muli o ke koko koko nui, pono pono nā lāʻau antihypertensive i kēlā me kēia lā. I ka wā i hala aku nei, he kōkua lōʻihi loa ʻo Tritace. Hoʻoponopono maikaʻi nā papa i ke ʻano o ke koko a ʻaʻole i ka hopena nā hopena. Me ka hoʻohana mau ʻana, pono ʻoe e lawe i nā hana wāwahi a hoʻonui paha i ka dosage, no ka mea, ʻaʻole pau ke kino ʻike i ka hopena o nā papa. ʻO ka hone wale nō ka momona ʻawaʻawa.
ʻO Elena Shashkina, 42 makahiki, Vladivostok
Ua hoʻokuʻuʻiaʻo Tritace i kona makuahine ma hope o kahi hōʻeha ma muli o ke koko kiʻekiʻe. Ua kōkua ka lāʻau lapaʻau - maikaʻi ka manaʻo momi, ua pau ka hoʻōki ikaika ikaika. Mālama ʻo Mom i ka helu haʻahaʻa ʻoi aku ka lōʻihi o ka lāʻau lapaʻau. Wahi a nā ʻōlelo a ke kauka, ma hope o ka malama o ke komo ʻana i ke ʻano he hoʻokahi mau pule. Pono kēia i nā ala ʻole a me nā mea pili i ka hoʻohui.
