ʻO Rosuvastatin SZ (North Star) nā lālā o nā statins e loaʻa kahi hopena lipid-lowing.
Hoʻohana maikaʻi ʻia ka lāʻau lapaʻau i nā maʻi e pili ana i ka hoʻoliʻi lipid metabolism, a no ka pale ʻana i kekahi mau palaka cardiovascular. Hiki i ka ʻike e pili ana i ka lāʻau lapaʻau i kēia kumuhana.
Ma ka mākeke lāʻau lapaʻau, hiki iā ʻoe ke loaʻa i nā lāʻau he nui i loaʻa iā rosuvastatin ka mea i lalo o nā hōʻailona. Hāpai ʻia ʻo Rosuvastatin SZ e ka mea hoʻokumu hale ʻĀlana North Star.
Aia ka papa i ka 5, 10, 20, a i ʻole 40 mg o ka calcium rosuvastatin. ʻO kona kumu nui ka ihi gula wai, povidone, sodium stearyl fumarate, primellose, MCC, aerosil a me ka calcium hydrophosphate dihydrate. ʻO nā papa ʻo Rosuvastatin SZ he biconvex, he pānaʻi a i uhi ʻia a uhi ʻia me ka uhi ʻulaʻula.
ʻO ka mea hana i ka mea pale mai HMG-CoA reductase. Hoʻolālā kāna hana i ka hoʻonui ʻana i ka nui o nā enzyme hepatic LDL, e hoʻonui ana i ka dissimilation o LDL a hōʻemi i kā lākou helu.
I ka hopena o ke hoʻohana ʻana i ka lāʻau lapaʻau, mālama ka mea maʻi i ka hōʻemi i ka pae o ka koloka "" maikaʻi "a hoʻonui i ke kaila o ka" maikaʻi ". Hiki ke mālama ʻia kahi hopena maikaʻi i 7 mau lā ma hope o ka hoʻomaka ʻana o ka mālama ʻana, a ma hope o nā lā 14 hiki ke hoʻokō ʻo 90% o ka hopena kiʻekiʻe. Ma hope o 28 mau lā, hoʻi ka lipid metabolism i ka maʻamau, ma hope o ka hana pono ʻia o ka lāʻau mālama.
ʻO ka ʻike kiʻekiʻe loa o ka rosuvastatin i nānā mau hola 5 ma hope o ka lawelawe waha.
Ma kahi kokoke o 90% o ka hana ikaika e hoʻopili ai i ka albumin. Lawe ʻia kona kāpae ʻia ʻana mai ke kino e nā ʻōpū a me nā ʻili.
Nā hōʻailona a me nā contraindications no ke hoʻohana
Ua kuhikuhi ʻia ʻo Rosuvastatin-SZ no ka maʻi lipid metabolism no ka pale ʻana o nā maʻi cardiovascular.
Ma ke ʻano he kānāwai, pono ka hoʻohana ʻana o kēia mau papa i ka pili ʻana i ka meaʻai a me ka haʻuki hyp hypololesterol.
Aia nā hōʻike hōʻike aʻoaʻo i kēia mau hōʻike aʻe no ka hoʻohana ʻana:
- ka mua, homozygous a i ʻole a i hui ʻia ka hypercholesterolemia (he hoʻohui i nā lāʻau lapaʻau ʻole);
- hypertriglyceridemia (IV) i kahi hoʻohui i ka meaʻai kūikawā;
- atherosclerosis (e pale i ka hoʻohemo ʻana o nā palaki kolesterol a me ka hoʻoponopono i ke kiʻekiʻe o ka nui o ka kolamu a me LDL);
- ka pale ʻana i ka hōʻeha hōʻeha, ka arterial revascularization a me ka hoʻopiʻi ʻana i ka naʻau (inā aia nā mea e like me ka wā kahiko, ke kiʻekiʻe o ka C-reactive protein, ka ulaula, nā genetics a me ke koko kiʻekiʻe).
Ua pāpā ke kauka i ka lāʻau lapaʻau Rosuvastatin SZ 10mg, 20mg a 40mg inā ua ʻike ʻia ma ka mea maʻi.
- ʻO ka hypersensitivity pilikino i nā ʻāpana.
- Hōʻea hōʻeha maikaʻi ʻole (me CC <30 ml / min).
- Glabose-galactose malabsorption, nele o ka lactase a i ʻole intolerance lactose.
- 18 makahiki;
- ʻO ka maʻi ʻōlohelohe o ka ate.
- ʻO ka hoʻopulapula nui o ka protein protease a me nā mākeke cyclosporin.
- Hoʻonui i ka pae CPK i ka 5 mau manawa a i ʻole e ʻoi aku i ka palena maʻamau.
- E hoʻolōʻihi i ka hoʻopiʻi myotoxic.
- ʻŌpū a me ka wā lactation.
- ʻO ka haʻahaʻa o ka ʻāʻī o nā wahine.
E hoʻohui i nā contraindications i ka hoʻohana ʻana o Rosuvastatin SZ me kahi waihona he 40 mg o ka hoʻohui i nā mea i luna aʻe.
- hōʻino ʻole i ke ake ʻole;
- hypothyroidism;
- no ka ʻohana Mongoloid;
- ke kīleʻomaʻi waiʻona;
- nā kūlana e hoʻonui ai i nā pae rosuvastatin.
Pēlā nō hoʻi kahi contraindication ma ka pilikino pilikino pilikino a pili ʻana i nā ʻōkuhi o nā ʻiʻo.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
E hoʻopau ʻia nā papa me ka wai inu. Lawe ʻia lākou ma kahi o ke kau ʻana i kēlā me kēia manawa o ka lā.
Ma mua o ka hoʻomaka ʻana a ma ka wā o ka lāʻau lapaʻau, hōʻole ka mea maʻi i nā huahana e like me nā huaʻala (nā ʻōpū, nā naʻau), ka ʻolika hua moa, ka puaʻa, ka lard, nā meaʻai momona ʻē aʻe, nā huahana i kā ʻia mai ka palaoa laʻa, ka ʻokala a me nā ʻala.
Ke hoʻoholo nei ke kauka i ka dosis o ka lāʻau lapaʻau e pili ana i ka pae o ka cholesterol, nā pahuhopu mālama a me nā hiʻohiʻona pilikino o ka mea maʻi.
ʻO ka maʻa mua o rosuvastatin he 5-10 mg i kēlā me kēia lā. Inā ʻaʻole hiki ke hoʻokō i ka hopena i makemake ʻia, ua hoʻonui ʻia ka nui ma 20 mg ma lalo o ka mākaʻikaʻi koʻikoʻi o kahi loea. Pono pono ke nānā pono ʻana i ka wā i kuhikuhi ai i ka 40 mg o ka lāʻau, i ka wā e hōʻike ai ka mea maʻi i ka maʻi koʻikoʻi o ka hypercholesterolemia a me nā manawa kiʻekiʻe o nā hihia cardiovascular.
14-28 mau lā ma hope o ka hoʻomaka ʻana o ka lāʻau lapaʻau, pono e nānā i nā lipid metabolism.
ʻAʻole pono e hoʻoponopono i ke ʻano o ka lāʻau lapaʻau i nā mea maʻi a me nā mea e maʻi nei i ka hana renal. Me ka polyformism genetic, kahiʻano i ka myopathy a i ʻole ai i ka lāhui Mongoloid, ʻaʻole ka nui o ka nui o ke ana o ka lipid-hoʻemi i ka 20 mg.
ʻO ka palena o ka mālama ʻana o ka mālama ʻana i ka pōpō lapaʻau ʻaʻoleʻoi aku ma mua o 25 degrees Celsius. ʻO 3 mau makahiki kahi ola. Mālama i ka pale i kahi wahi i pale ʻia mai ka umu a me ka lā.
Nā Kūlana ʻaoʻao a me ka hoʻohālike
ʻO ka papa inoa holoʻokoʻa o nā hopena hopena e hiki mai ana i ka wā e hoʻohana ai i ka lāʻau lapaʻau i wehewehe ʻia i nā ʻōkuhi no ka hoʻohana.
Ma ke ʻano he kānāwai, ʻokoʻa loa ka hopena o ka wā ke lawe nei i kēia lāʻau lapaʻau.
ʻOiai ke ʻano o nā hiʻohiʻona maikaʻi ʻole, ʻōmaʻomaʻo lākou a haʻalele iā lākou iho.
I nā ʻōlelo ʻōlelo no ka hoʻohana ʻana, e hōʻike ʻia nei ka papa inoa o nā hopena ʻaoʻao.
- Pūnaehana Endocrine: kahi hoʻomohala o ka non-insulin-dependant diabetes mellitus (type 2).
- Pūnaehana immune: Quincke edema a me nā ʻano hopena hypersensitivity.
- CNS: hōʻeha a me ka migraine.
- ʻŌnaehana urinary: proteinuria.
- ʻO ka maʻi Gastrointestinal: maʻi dyspeptic, ʻeha o ka epigastric.
- ʻŌnaehana musculoskeletal: myalgia, myositis, myopathy, rhabdomyolysis.
- ʻIli: kala, hina, a hoʻi ʻole.
- Pūnaehana Biliary: pancreatitis, hana kiʻekiʻe o nā transaminases hepatic.
- Nā hōʻailona Laboratory: hyperglycemia, kiʻekiʻe kiʻekiʻe o ka bilirubin, ka phosphatase alkaline, ka hana GGT, ka hana thyroid.
Ma ka hopena o ka noiʻi ʻana ma hope o ka noiʻi ʻana, ua hōʻike ʻia nā hopena maikaʻi ʻole:
- thrombocytopenia;
- jaundice a me ka hepatitis;
- Maʻiʻo Stevens-Johnson;
- nā hana hoʻomanaʻo hoʻomanaʻo;
- pulu;
- polyneuropathy diabetic;
- kekahikecia;
- hematuria;
- ka pōkole o ka hanu a maloʻo maloʻo;
- aolaila.
I kekahi mau hihia, hiki i ka hoʻohanaʻana o Rosuvastatin SZ me nā lāʻau lapaʻau hiki ke alakaʻi i nā hopena hiki ʻole ke kiʻi ʻia. Aia ma lalo aʻe nā hiʻohiʻona o ka lawelawe o ka lāʻau lapaʻau i ka nīnau ʻana me nā poʻe ʻē aʻe:
- Ke halihali ka palaka protein transport - he hoʻonui i ka nui o ka myopathy a me ka hoʻonui i ka nui o ka rosuvastatin.
- ʻO nā blockers HIV protease - hoʻonui ʻia i ka hōʻike o ka mea ikaika.
- Cyclosporine - he hoʻonui i ka nui o ka rosuvastatin ma mua o 7 mau manawa.
- ʻO Gemfibrozil, fenofibrate a me nā fibrates ʻē aʻe, waikawa nikotinic - ke kiʻekiʻe o ka hana ikaika a me ka hopena o ka myopathy.
- Erythromycin a me nā antacids e loaʻa ana i ka alumini a me ka magnesium hydroxide - kahi e hoʻemi ana i ka manaʻo o ka rosuvastatin.
- Ezetimibe - he hoʻonui nui o ka neʻe ʻana o ka mea hana.
I mea e pale ai i ka hoʻomohala ʻana o nā hopena maikaʻi ʻole ma muli o ka hoʻohana like ʻana o nā lāʻau kūpono ʻole, pono ia e hōʻike i ke kauka e pili ana i nā maʻi āpau.
Kumukūʻai, nā loiloi a me nā hoʻohālike
Mai ka hopena o ka lāʻau lapaʻau Rosuvastatin e ka lāʻau lapaʻau ʻĀina "North Star", ʻaʻole kiʻekiʻe loa kona kumukūʻai. Hiki iā ʻoe ke kūʻai i ka lāʻau lapaʻau ma kekahi lāʻau lapaʻau ma ke kauhale.
ʻO ke kumu kūʻai o kahi pākahi i loaʻa iā 30 mau papa o 5 mg kēlā me kēia mea he 190 rubles; 10 mg kēlā me kēia - 320 ka rubles; 20 mg pākahi - 400 rubles; 40 mg pākahi - 740 mau rubles.
I waena o nā poʻe maʻi a me nā kauka, hiki iā ʻoe ke loaʻa nā loiloi maikaʻi e pili ana i ka lāʻau lapaʻau. ʻO ka mea nui he uku kūpono a kūpono hoʻi i ka hopena therapeutic ikaika. Eia nō naʻe, aia kekahi mau manaʻo maikaʻi ʻole e pili ana i ka hele ʻana o nā hopena ʻaoʻao.
Eugene: "Ua loaʻa iaʻu kahi manawa i ka lipid metabolism ma kahi lōʻihi aku. Ua hoʻāʻo wau i nā lāʻau lapaʻau pinepine no ka manawa holoʻokoʻa. Lawe wau iā Liprimar i ka wā mua, akā naʻe, no ka mea, ua kumukūʻai kona kumukūʻai. Akā, i kēlā me kēia makahiki koʻu pono e hana ai i ka poʻe ʻōpala e hoʻolako i nā moku utak. Ua kuhikuhi mai ʻo Krestor iaʻu, eia naʻe, ʻaʻole ia he lāʻau lapaʻau maʻalahi. Ua loaʻa iaʻu kahi kūlohelohe i nā kūmole, aia ʻo Rosuvastatin SZ.
Tatyana: "I ke kauwela, ua piʻi ka pae kolamu i ka 10, i ka manawa 5.8 ka mea i hele aku au i ka mea lapaʻau a ua kuhikuhi mai ʻo ia iaʻu iā Rosuvastatin. Ua ʻōlelo ke kauka ʻaʻole he hopena haʻahaʻa o kēia lāʻau ma ka palaka. akā hoʻokahi nō "akā" - ke kāuhi ʻole iā ʻoe ma kekahi manawa. "
Loaʻa ka hana mana o rosuvastatin i nā lāʻau lapaʻau he nui i hana ʻia e nā mea hana like. ʻ includelelo pū kekahi:
- Akorta;
- ʻOkaʻohana
- Mertenyl;
- Rosart
- Ro-Statin;
- Rosistark;
- Canu Rosuvastatin;
- Roxer;
- ʻĀpana.
Me nā hypersensitivity pilikino i ka rosuvastatin, koho ke kauka i kahi analogue kūponoʻole, i.e. kahi māka i loaʻa i kekahi ʻāpana ikaika, akā hana i ka hopena like ʻole. I loko o ke kalapona hiki ke kūʻai i nā lāʻau like ʻole:
- Atorvastatin.
- Nā mea kokoke.
- Vasilip.
- Vero-simvastatin.
- Zokor.
- ʻĀlelo Simgal.
ʻO ka mea nui ma ka mālama ʻana i ke kolamu kiʻekiʻe ʻo ka mālama ʻana i nā ʻōlelo a pau o ka mea hele ʻana i ka loea, hele i kahi kīʻai a alakaʻi i kahi ʻano hana. Pēlā, e hiki ai ke hoʻomalu i ka maʻi a pale i nā ʻōnaehana like ʻole.
ʻO ka hua lāʻau Rosuvastatin SZ i wehewehe kiʻi ʻia i ka wikiō ma kēia ʻatikala.
