ʻO ka lāʻau Baeta he waiwai hypoglycemic a hoʻohana ʻia i ka wā o ka mālama ʻana i ka maʻi mellitus type 2. ʻO kēia mea hana he exenatide, ka mea i manaʻo ʻia he amidopeptide amino acid.
Hoʻonui ka lāʻau lapaʻau i ka mea huna o ka honi haʻahaʻa o ke kō a kōkua i ka mālama ʻana i ka glycemia. Ma ka manawa like, e hoʻolei ana i ka hakahaka o ka ʻōpū a hoʻoikaika i ka hana o nā poli beta o ka pancreas.
E kōkua kēia moʻolelo e hoʻomaopopo iā ʻoe i nā hihia e pono ai ʻoe e lawe i ka lāʻau lapaʻau, a ma loko e hiki ai ke hōʻeha i ka mea maʻi me ka maʻi maʻi maʻi maʻi.
ʻO nā hiʻohiʻona maʻamau o ka lāʻau
ʻO ka lāʻau lapaʻau ʻo Baeta he hana kuhi ʻole no ka subcutaneous infusion. ʻO ka mea hana a ka mea lapaʻau he exenatide, loaʻa nō hoʻi i kahi mea liʻiliʻi o ka sodium acetate trihydrate, metacresol, mannitol, acetic acid, ka wai aʻa. Hoʻokuʻu lākou i ka lāʻau lapaʻau i ke ʻano o nā ampoules (250 mg), loaʻa kēlā me kēia peni syringe kūikawā me ka nui o ka 1,2 a me ka 2.4 ml.
ʻO ka poʻe maʻi e lawe nei i kēia lāʻau lapaʻau e nānā i ka emi ʻana o ke kō o ke koko ma muli o kēia ʻano hana:
- Hoʻonui ʻo Byeta i ka hoʻokuʻu ʻana o ka insulin mai ka parenchyma me ka hoʻonui nui o ka glucose i ke kahe koko o kekahi kanaka.
- Ua pau ka huna ʻana o Insulin i ka manawa e hāʻule ai nā pae o ke kō.
- ʻO ka hana hope loa e hoʻomau i nā kaila koko.
I ka poʻe e ʻeha ana i ka lua o ke ʻano o ka maʻi maʻi, ka hoʻohana ʻana o ka lāʻau lapaʻau i kēlā mau loli.
- Kāohi ʻana i ka hana o ka momonaagonagon nui, ka mea e pale ai i ka insulin.
- Ke hoʻonani o ka huila o ka gastric motility.
- Hoʻemi i ka momona.
Ke lawelawe ʻia nei ka lāʻau lapaʻau e ka subcutaneously, hoʻomaka ke hana ikaika e hana koke a hiki i kona kūlana kiʻekiʻe ma hope o ʻelua mau hola.
Hoʻopau kūʻokoʻa ka hopena o ka lāʻau i hope o kahi lā.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
ʻO ke kauka hele wale nō e hiki ke kuhikuhi i ka lāʻau lapaʻau, ʻaʻohe hihia e hoʻōla pono iā ʻoe iho. Ma hope o ka loaʻa ʻana o ka lāʻau lapaʻau Baeta, pono e ʻike pono ʻia nā ʻōkuhi no ka hoʻohana ʻana.
Ke hōʻike nei no ka hoʻohana ʻana i kēia lāʻau lapaʻau type 2 ʻano maʻi me ka mono- a i ʻole lāʻau lapaʻau hou. Hoʻohana ʻia ia i ka wā hiki ʻole ke hoʻokele kūpono i ka pae o ka glycemia. Hiki i ka lāʻau lapaʻau ke hoʻohui pū me ia mau ʻano:
- Metformin;
- Thiazolidinedione;
- kumuliiu aoli;
- ka hui pū ʻana o ka metformin, sulfonylurea;
- nā hui ʻana o ka metformin a me thiazolidinedione.
ʻO ka hopena o ka hopena o 5 μg ʻelua mau manawa i ka lā no kahi hola ma mua o ka lawe ʻana i ka ipu nui. Ke hoʻohālikelike ʻia ia i loko o ka palupalu, ʻāha a me ka ʻōpū paha. Ma hope o kahi mahina o ka hoʻokō kūleʻa, e hoʻonui ʻia ka dosage i 10 mcg ʻelua i ka lā hoʻokahi. Inā hoʻohana ʻia ka lāʻau lapaʻau i hui pū me ka derivatives sulfonylurea, pono e hoʻemi ʻia ka nui o ka hopena e pale ai i ke kūlana hypoglycemic maʻi.
Pono e nānā ʻia nā lula no ka lawelawe ʻana i ka lāʻau.
- ʻaʻole hiki ke lawelawe ʻia ma hope o ka ʻai ʻana;
- ʻaʻole pono e hoʻokomo i ka intramuscularly a i ʻole intravenously;
- inā ua pouli ka loli a hoʻololi ʻia ke kala, ʻoi aku ka maikaʻi;
- inā i loaʻa nā lālā i ka hoʻonā, pono e hoʻopau ʻia ka lawelawe ʻana o ka lāʻau;
- i ka wā ʻo Bayeta therapy, hiki ke hoʻāla ʻia nā antibody.
Pono mālama ʻia ka lāʻau i kahi wahi i pale ʻia mai ka mālamalama a me nā keiki liʻiliʻi. Pono e mālama ʻia ke aniani o ka mālama mai i ka pae mai 2 a 8 mau kiʻekiʻe, no laila ʻoi aku ka maikaʻi o ka mālama ʻana i ka lāʻau lapaʻau i loko o ka friji, akā mai hoʻokaʻawale.
ʻO 2 mau makahiki ka ola o ka puʻina o ka huahana, a ʻo ka hoʻonā ʻana i nā syringe peni he 1 mau mahina ma ke kau ʻana ma mua o 25 mau kiʻekiʻe.
ʻO ke kumukūʻai o ka lāʻau lapaʻau a me nā loiloi
Hiki ke kūʻai ʻia ka lāʻau Baeta ma kekahi lāʻau lapaʻau a waiho i kahi kauoha i loko o kahi lāʻau lapaʻau pūnaewele. Pono e kūʻai ʻia ma ke kūʻai ʻana i ka lāʻau. Mai ka mea hana o kēia huahana ʻo Suetena, ma muli o kāna kumu ke kiʻekiʻe nui.
No laila, ʻaʻole nā kānaka maʻamau āpau i kahi maʻi o ka maʻi maʻi hiki ke kūʻai i kēlā lāʻau lapaʻau. Kūlike ke kumukūʻai ma ke ʻano o ka hoʻokuʻu ʻana o nā kālā.
- 1,2 ml syringe pen - mai 4246 a 6398 rubles;
- 2.4 ml penikala syringe - mai 5301 a 8430 mau rubles.
ʻO ka manawa nei i alakaʻi ʻia i ka noiʻi marketing, ka mea i mālama ʻia e nā poʻe maʻi i koho i ka lāʻau. E hōʻike ana i ka lāʻau lapaʻau Bayeta, nona nā loiloi e hōʻike nei i ke ʻano o nā hopena maikaʻi aʻe nei:
- ʻO ka hoʻonāukiuki o nā io o nā nūnū: nāwaliwali, ka huakaʻi a i ʻole ka hemahema o ka ʻono.
- Hoʻololi i ka metabolism a me kaʻai: kaumaha kaumaha, dehydration ma muli o ka luaʻi.
- ʻO kahi hanana koʻikoʻi nui ia o ka hopena anaphylactic.
- Nā maʻi a me nā ala o ke kahelehe kūwili: hoʻonui i ka hoʻomohala honua, constipation, pancreatitis maʻa (i kekahi manawa).
- ʻO nā loli i ka urination: impalired function renal, hoʻonui i nā kiʻekiʻe creatinine, renal failed a i ʻole kona hoʻohui.
- ʻO nā maʻi kūlohelohe ka ʻili: alopecia (hōʻemi i ka lauoho), kahakaha, urticaria, angioedema, maculopapular rashes.
ʻO kaʻoiaʻiʻo, ʻo ka manaʻo maikaʻi ke kumu kūʻai o nā laʻana, ʻo ia ke kumu no ka nui o nā mea maʻi me ka maʻi diabetes i kā lākou mau loiloi ma ka Pūnaewele. Akā, ʻoiai, ʻo ka lāʻau lapaʻau e hoʻōla maoli i ka pae o ka glucose i ke koko o ka mea maʻi a kōkua i ka hakakā nui ʻana.
Eia kekahi, ma muli o nā mea hoʻohālike o kona hopena therapeutic, ʻaʻole ia e hoʻokau i ka hōʻeha hypoglycemia.
Nā hiʻohiʻona a me nā hopena maikaʻiʻole
I kekahi mau hihia, lawe ʻia ka lāʻau lapaʻau ma muli o ka hele ʻana o contraindications i ka mea maʻi. Hiki iā ia:
- maʻi ketoacidosis maʻi 'ōpū - hana hewa i ka metabolism o nā kālaiʻu;
- insulin-puka puka o ka maʻi diabetes;
- pilikia ʻole ʻole a me CC ma mua o 30 ml / min;
- ke ʻano o ka huina a ke ʻole o ka gastroparesis;
- ka ʻana ʻole o kēlā me kēia ʻāpana o ka lāʻau;
- na keiki a me na opio malalo o na makahiki 18;
- ka manawa o ka hānau ʻana i kahi keiki a me ka umauma.
Me ka hoʻohana pono ʻole a i ʻole nā kumu ʻē aʻe, e loaʻa ai nā hopena ʻinoʻino.
- nā kuʻikena, ʻo ia hoʻi urticaria, ʻiliʻā o ka ʻili, a me nā meaʻeha;
- hoʻoweliweli ʻōpana - nausea, luaʻi, flatulence, ʻeha, constipation, hoʻemi ʻia ke kaumaha o ke kino a me ka momona;
- nā hana ʻole o ka ʻōnaehana o ka hoʻopili, ʻo ia hoʻi ka puʻupuʻu, kūlohelohe, ʻeha;
- kōmona / kāpili hema ʻole;
- ka hoʻonui ʻana o ka manawa puʻuwai;
- ka hoʻomohala ʻana o ka hypoglycemia, pancreatitis, hyperhidrosis;
- he hoʻonui ma serum creatinine.
I nā hihia o nā hopena maikaʻiʻole, hiki i ka mea haipule ke komo i ka hoʻoponopono lāʻau lapaʻau me kēia lāʻau a hōʻoki paha i kona hoʻohana ʻana i ka nui.
Nā hiʻohiʻona o ka lāʻau
I ka hihia ʻaʻole hiki ke hoʻokele ʻia ka mea maʻi i kēlā mau pahuhopu a manaʻo paha ʻo ia i ka hopena maikaʻiʻole, hiki i ke kauka ke hele nei i hoʻololi i nā mea aʻoaʻo o ka mālama ʻana. Ua hana kēia i ʻelua ala nui - ma ka hoʻololi ʻana i ke ʻano o ka lāʻau a i ʻole e haʻalele iā ia. I ka lua o ka hihia, pono e koho i nā lāʻau lapaʻau ʻenehana e loaʻa iā ia ka hopena therapeutic a ʻaʻole ʻinoʻino i ke kino maʻi maʻi.
E like me kēia, ʻaʻohe ʻano like o Baeta. ʻO nā AstraZeneca lāuaʻo Bristol-Myers Squibb Co (BMS) wale nō nā mea hana 100% analogues o kēia lāʻau lapaʻau (generics). ʻElua mau ʻano o nā lāʻau lapaʻau ma ka mākeke lāʻau Lūkini, kahi i like like i ko lākou hopena therapeutic. E pili ana kēia:
- ʻO Victoza kahi lāʻau lapaʻau e like me Baeta, he mimetin mimetic. Hāʻawi ʻia ka lāʻau lapaʻau ma ke ʻano o nā ʻāpana syringe no nā infusion subcutaneous i ke ʻano maʻi type 2. ʻO ka hoʻohana mau ʻana i ka lāʻau lapaʻau e kōkua i ka hoʻemi ʻana i ka pae o ka hemoglobin glycated i 1,8% a nalowale i ka 4-5 kg ka manawa o ka makahiki o ka ʻoihana. Pono e hoʻomaopopo he kauka i hiki i ke kauka ke koho i ka kūpono o kekahi lāʻau lapaʻau. ʻO ka kumukūʻai maʻamau (2 peni syringe o 3 ml) he 10,300 mau rubles.
- ʻO kaviavia ka mea i hoʻohui i ka wai koko i ka mālama ʻana i ka maʻi maʻi 2. Loaʻa i nā palapala papa. ʻO ka kumukūʻai kūpono o kahi lāʻau lapaʻau (28 mau pūʻulu, 100 mg) ka 1672 rubles, ʻo ia ka mea haʻahaʻa loa i waena o nā lāʻau lapaʻau i nīnau ʻia. Akā ʻo ka nīnau a ka mea e hana i ka hopena e ʻoi aku ka maikaʻi o ka kauka.
A pēlā nō, ʻo ka lāʻau lapaʻau Bayeta he mea waiwai e hoʻomaʻamaʻa hypoglycemic maikaʻi. Aia kona hopena therapeutic kekahi mau hiʻohiʻona e kōkua i ka hoʻokō piha i ka mana glycemic. Akā naʻe, ʻaʻole hiki ke hoʻohana ʻia ka lāʻau lapaʻau i kekahi mau hihia, a hiki pū kekahi i nā hopena maikaʻi ʻole.
No laila, ʻaʻole pono nā mālama pilikino. Pono e hoʻokō i kahi huakaʻi i ke kauka nāna i kuhikuhi pololei i ka pono e hoʻohana i ka lāʻau lapaʻau, me ka noʻonoʻo ʻana i nā hiʻohiʻona o ke kino o kēlā me kēia maʻi. Me nā kūpono kūpono a me ka hahai ʻana i nā lula a pau no ka hoʻopuka o ka hopena, hiki iā ʻoe ke hōʻemi i ke kō i nā pae maʻamau a haʻalele i nā hōʻailona o ka hyperglycemia. ʻO ke wikiō ma kēia ʻatikala e kamaʻilio e pili ana i nā lāʻau lapaʻau maʻi.
