Nā papa kiʻi Amaryl - nā ʻōkuhi, nā loiloi kumu, kūʻai

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ʻO Amaryl i loko o kahi glimepiride, nona nā mea hou a ʻekolu, ka hanauna o ka derogatives sulfonylurea (PSM). ʻOi aku kēia lāʻau lapaʻau ma mua o ka glibenclamide (Maninil) a me ka glyclazide (Diabeton), akā ke kūlike ke kumukūʻai i ke kumukūʻai kiʻekiʻe, hana wikiwiki, hoʻohaʻahaʻa i ka pancreas, a me kahi haʻahaʻa haʻahaʻa o hypoglycemia.

Me Amaril, hemo lohi ana nā ʻōle o ka beta ma mua o nā hanauna o ka wā o ka sulfonylureas, no laila e lohi ana ka hoʻomohala o ka maʻi diabetes a e makemake ʻia ka hana maʻi insulin ma hope.

Hōʻikeʻike ka ʻikepili i ka lāʻau lapaʻau: E hoʻemi maikaʻi ia i ka kō, ua maʻalahi ka hoʻohana ʻana, inu lākou i nā papa i hoʻokahi lā i ka lā, me ka ʻaʻa o ka nui. Ma kahi o ka glimepiride maʻemaʻe, ua hui pū me kona metformin - Amaril M.

ʻ .lelo pōkole

HoʻolahaHoʻēmi i ke kō koko, pili i kona pae ma nā ʻaoʻao ʻelua:

  1. Hoʻokomo i ka synthesis o ka insulin, a hoʻihoʻi i ka hapa mua, wikiwiki wikiwiki o kāna hilo. ʻO ke koena ʻo PSM ka pau i kēia hana a hana i ka lua, no laila e emi iki ka nui o ka meli.
  2. Hoʻemi i ka pale ʻana o ka insulin i ka ikaika ma mua o nā PSM ʻē aʻe.

Eia kekahi, ʻo ka lāʻau lapaʻau e hōʻemi i ka hopena o ka trombosis, hoʻōla i ka cholesterol, a hoʻēmi i ka hoʻonaninani oxidative.

Hoʻopili ʻia ʻo Amaryl ma ka ʻāpana i ka urine, mahele ma waena o ke kaomi ʻana o ka wahie, no laila hiki ke hoʻohana ʻia i ka poʻe maʻi me ka hiki ʻana o ka hana, inā ua mālama ʻia nā hana o ka pūpū.

Nā HōʻikeHoʻopili wale ʻia nā maʻi maʻi maʻi 2 ʻano. ʻO kahi mea mua no ka hoʻohana ʻana i mālama ʻia i nā ʻāpana beta mau, ke koena syntact o kā lākou iho ponoʻī. Inā ua hoʻōki ka pancreas e hana i ka hormone, ʻaʻole i kuhikuhi ʻia ʻo Amaril. Wahi a nā ʻōlelo kuhikuhi, hiki ke lawe ʻia ka lāʻau lapaʻau me ka metformin a me ka lāʻau maʻi insulin.
ʻĀnō

Hana ʻia ʻo Amaryl i ke ʻano o nā papa i pili i ka 4 mg o ka glimepiride. No ka maʻalahi o ka hoʻohana, kau ʻia kēlā me kēia kala.

ʻO ka lā hoʻomaka e 1 mg. Lawe ʻia no 10 mau lā, ma hope o ka hoʻomaka ʻana e hoʻonui lohi a hiki i ke kaulike ʻana i ke kō. ʻO ka palena ʻokoʻa loa ka 6 mg. Inā ʻaʻole e hāʻawi i ka uku no ka maʻi diabetes, ua hoʻohui ʻia nā lāʻau mai nā hui ʻē aʻe a i ʻole i ka insulin i ka regimen mālama.

Ke keuKe hōʻike nei i ka nui o ka nui o ka nui e alakaʻi i ka hypoglycemia lōʻihi. Ma hope o ka normalization o ke kō, hiki iā ia ke hāʻule pinepine no kekahi 3 mau lā. I kēia manawa āpau, aia ka mea maʻi ma lalo o ka nānā ʻana o nā hoahānau, me kahi overdose ikaika - i loko o ka hale hoʻomaha.
Nā Hoʻohui
  1. ʻO ka maʻi hypersensitivity i ka glimepiride a me nā PSM, nā mea kōkua o ka lāʻau.
  2. Kuhiʻole i ka insulin intrinsic (type 1 diabetes, pancreatic resection).
  3. ʻO kahi pale hoʻokū maikaʻi. ʻO ka hiki ʻana o ka lawe ʻana iā Amaril no nā maʻi o ka maʻi ma hope ma hope o kahi loiloi o ke kino.
  4. Hoʻopili ʻia ka Glimepiride i loko o ka ʻai, no laila, hoʻopili ʻia ka puʻuwai i nā ʻōlelo a like me kahi contraindication.

Hoʻololi iki ʻia ʻo Amaryl a hoʻololi ʻia me ka inikini insulin i ka wā hapai a me ka lactation, nā hopena hoʻonāukiuki o ka maʻi maʻi, mai ka ketoacidosis a hyperglycemic coma. Me nā maʻi maʻi hopohopo, nā hōʻeha, nā kaumaha hoʻonaninani, ʻaʻole lawa paha ʻo Amaril e hoʻomaʻamaʻa i ke kōpaʻa, no laila e hoʻopili ʻia ka mālama ʻana me ka insulin, e maʻamau loa.

Ka hopena o ka hypoglycemia

Holo ke kō o ke koko inā hoʻopoina ka mea maʻi i ka ʻai a ʻaʻole i hoʻoulu hou i ka glucose i hoʻokaʻina i ka wā o ka hoʻomaʻamaʻa. No ka hana maʻamau i ka glycemia, pono ʻoe e lawe i nā kīhai wikiwiki, maʻamau ʻo ia kahi ʻāpana gula, kahi kīʻaha o kaʻaila a i ʻole kaʻaēmi e lawa.

Inā ua hoʻonui ʻia ka nui o ka make ʻana o Amaril, hiki i ka hypoglycemia ke hoʻi hou i nā manawa he nui i ka manawa o ka lāʻau. I kēia hihia, ma hope o ka hoʻokaʻa mua ʻana o ke kō, hoʻāʻo lākou e hoʻokaʻawale i ka glimepiride mai ka huina o ka huina: e hoʻonāukiuki lākou i ka luaʻi, inu i nā adsorbents a i ʻole laxative. Ua make ka overdose koʻikoʻi; ʻo ka mālama ʻana no ka hypoglycemia koʻikoʻi e loaʻa i ka glucose intravenous mandatory.

Nā hopena hopenaHoʻohui hou aku i ka hypoglycemia, i ka wā e lawe ai iā Amaril, ʻike ʻia nā pilikia o ka kū ʻana (ma ka haʻahaʻa o ka 1% o nā maʻi), nā maʻi kūlohelohe, mai ka ʻāʻī a me ka hōʻaiʻe i ka anaphylactic shock (<1%), nā hopena kūloko mai ka puʻuwai, hoʻololi i ka hui koko (<0.1%) . ^ E Ha yM.
ʻLelo ʻia a me GVKaki kikowaena papaʻi i ka mālama ʻana me Amaril i ka wā hāpai a me HBV. ^ E Ha yM. E hele ana ka lāʻau lapaʻau i ka pale o ka placental a komo i ke koko o ka hapalua, ke komo i ka waiū umauma. Inā he hapai a lactating a maʻi maʻi maʻi paha e hoʻoki ʻole i ka lawe ʻana i ka lāʻau lapaʻau, mālama nui ke keiki i ka hypoglycemia.
Hoʻohui nūhouHiki ke loli paha ka hopena o Amaril me ka hoʻohana pinepine ʻana i nā lāʻau ʻē aʻe: nā hana hormonal, antihypertensive, kekahi mau antibiotics a me nā ʻaila antifungal. Aia ka papa inoa piha i nā kuhikuhi no ka hoʻohana.
HōʻikeʻO ka mea hoʻonaninani he glimepiride (ʻo Amaril M he glimepiride a me ka metformin), nā mea kōkua no ka hoʻokumu ʻana i ka papa a hoʻonui i kona nohona papa: sodium glycolate, lactose, cellulose, polyvidone, magnesium stearate, ʻele.
Mea hanaHana ʻia ʻo Sanofi Corporation, i hana ʻia ka glimepiride i Kelemania, nā papa a me nā ʻāpana i Italia.
Kūʻai

Amaryl: 335-1220 rub. no nā papa he 30, hilinaʻi ke kumukūʻai ma ka waihona. ʻO ka pākī nui loa - 90 mau papa o 4 mg kēlā me kēia kumukūʻai e pili ana i 2700 mau rubles.

Amaril M: 750 ʻōpala. no 30 papa.

Laki3 mau makahiki Pono e mālama ʻia ka lāʻau lapaʻau ma waho o ka hiki ʻana i nā keiki, me ka hoʻohana ʻole ʻana ma Amaril i hiki ʻole ke hōʻeha i ka olakino.

Nā Mana Kūʻai

Ua hōʻike ʻia nā papa ʻaina Amaryl i ʻelua mau hihia:

  1. Inā ʻaʻole e hoʻomau ka maʻi diabetes i ka makahiki mua, ʻaʻole lawa ka metformin e uku ai iā ia.
  2. I ka hoʻomaka ʻana o ka hoʻōla, me ka metformin a me ka meaʻai, inā ua ʻike ʻia ka hemoglobin glycated kiʻekiʻe (> 8%). Ma hope o ka hoʻopiʻi ʻana i ka maʻi, ua emi ka pono no ka lāʻau hypoglycemic, a hoʻopau ʻia ʻo Amaryl.

Lawe ʻia ka lāʻau me ka meaʻai.. ^ E Ha yM. ʻAʻole hiki ke wāwahi ʻia ka papa, akā hiki ke hoʻokaʻawale i ka hapalua. Pono ke hoʻomaʻemaʻe Amaril e hoʻoponopono i kaʻai.

ʻO ka maʻi maʻi a me nā hoʻohaʻahaʻa manaʻo e hana ia i ka wā ma mua

  • Ka hana maʻamau o ke kō -95%
  • Hoʻokuʻuina o ka pua thrombosis - 70%
  • Hoʻopau i kahi puʻuwai ikaika -90%
  • Hoʻopau i ke kiʻekiʻe o ke koko - 92%
  • ʻO ka hoʻonuiʻana i ka ikehu i ka wā, hoʻomaikaʻi i ka hiamoe i ka pō -97%
  • ka ʻai ʻana a lākou e lawe ai i ka paila;
  • I ka pau ʻana āu e hele ai i ka ʻai. Inā hiki ʻole e loaʻa ka ʻaina kakahiaka, ua hoʻohuli ʻia ka hoʻokipa ʻana a Amaril i ka ʻaina ʻaina;
  • pono ia e hoʻonohonoho i kahi hoʻokomo o nā hāmeʻene pale i ke koko. Loaʻa kēia pahuhopu e ka ʻai mau (ma hope o 4 mau hola), ka hoʻoili ʻana o nā mea kālaiʻai i nā kīʻaha āpau. ʻO ka haʻahaʻa o ka huaʻōlelo glycemic o ka meaʻai, ʻoi aku ka maʻalahi e loaʻa ai ka hoʻopaʻi ʻana i ka maʻi diabetes.

Ua inu nui ʻo Amaril no nā makahiki ʻole me ka ʻole o ka haki. Inā ua kāpae ka palena kiʻekiʻe e hoʻemi i ke kō, hiki pono ke huli i loko o ka ʻohi ʻana i ka insulin.

He manawa hana

Loaʻa i ka Amaryl piha bioavailability, 100% o ka lāʻau lapaʻau e hōʻea i kahi o nā hana. E like me nā kuhikuhi, ua hoʻokumu ʻia ke kāʻei nui o ka glimepiride i ke koko ma hope o 2 mau hola. ʻO ka lōʻihi o ka lōʻihi o ka hana he 24 mau hola, ʻoi aku ke kiʻekiʻe o ke kau, ʻoi aku ka lōʻihi o nā papa Amaril.

Ma muli o kona lōʻihi lōʻihi, ke ʻae ʻia ka lāʻau lapaʻau i hoʻokahi manawa i ka lā. ʻAʻole makemake i 60% o nā maʻi maʻi e koi ikaika i nā ʻōlelo a ke kauka, hiki i ka lāʻau hoʻokahi ke hōʻemi i ka hōʻemi ʻana o nā lāʻau lapaʻau ma 30%, no laila e hoʻomaikaʻi ai i ke ala o ka maʻi maʻi.

Hoʻolaha ka waipuna

Hoʻopilikia ka ʻawaʻawa ʻawa iā Amaryl hiki ʻole ke hāpai hou iā lākou a hoʻomaikaʻi i kāna hopena. Hōʻihi ka pilikia o ka pilikia me ka haole hypoglycemia, hoʻomaka me kahi pae hoʻemi haʻahaʻa. Wahi a nā maʻi maʻi, he palekana palekana ka wai o ka wai ʻaʻole iʻoi aku i kahi aniani o ka vodka a i kahi aniani paha o ka waina.

Nā mea hoʻohālikelike o Amaril

ʻO ka lāʻau lapaʻau he nui o nā analogue eʻoi aku me ka waiwai o nā mea like a me nā wai, nā mea i kapa ʻia ʻo nā mea kikoʻī. ʻO ka maʻamau, eia nā papa o ka hoʻopili hale, mai nā huahana i hiki ke kūʻai iā ʻoe ke kūʻai wale i ka Croatian Glimepirid-Teva. Wahi a nā loiloi, ʻaʻoleʻoi aku ka hewa o nā mea kikowaena Lūkini ma mua o ka lawe ʻana iā Amaril.

Nā mea hoʻohālikelike o AmarilAupuni kūkuluMea hanaKūʻai no ka palena liʻiliʻi, hoʻomoʻa.
GlimepirideLūkia

Kauʻai

Alanui

Lapaʻau

Laau-Leksredstva,

110
Canon GlimepirideHoʻolaha Canonfarm.155
HaipuleAkrikhin180
Glimepiride-tevaKroasiaPliva o Khrvatsk135
GlemazʻApenekiaKimika Montpellierloaʻa i loko o nā hale kūʻai

Amaryl or Diabeton

I kēia manawa, ʻo glimepiride a me ke ʻano o ka glyclazide (Diabeton MV a me nā analogues) i manaʻo ʻia ʻo ia ka PSM hou a palekana. Ua emi iki nā lāʻau ʻelua ma mua o ko lākou mau kūpuna e hana i ka hypoglycemia koʻikoʻi.

A ʻoi, ʻoi aku ka makemake o nā papa Amaryl no ka maʻi diabetes.

  • pili ka luhi i nā maʻi o nā mea maʻi;
  • ʻaʻole i hoʻopiʻi ʻia kahi hopena maikaʻi ʻole i ka ʻōnaehana cardiovascular;
  • koi aku nā maʻi maʻi i ka haʻahaʻa o ka lāʻau (ʻo ke kiʻekiʻe loa o Diabeton e like me 3 mg o Amaril);
  • ʻO ka hoemi ʻana o ke kō i ka wā e lawe ana iā Amaril e ka hui pū me ka piʻi haʻahaʻa o nā pae insulin. No Diabeton, ʻo kēia māhele he 0,07, no Amaril - 0,03. I ke koena PSM ke koe, ua hewa ka ʻike: 0.11 no glipizide, 0.16 no glibenclamide.

Amaryl a i ʻole Glucophage

Ke ʻōlelo wiwo ʻole nei, ʻaʻole paha e hoʻopiʻi ʻia ka nīnau iā Amaril a i ʻole Glucophage (metformin). Hoʻololi mau ʻia ka Glucophage a me nā mea hoʻohālikelike no ka maʻi type 2 like ʻole, no ka mea i ʻoi aku ka maikaʻi ma mua o nā lāʻau ʻē aʻe e hana ana i ke kumu nui o ka maʻi - ke kūʻē ʻana i ka insulin. Inā ʻōlelo wale ke kauka i nā papa ʻelua o Amaryl, he mea kūlike kona hoʻokūkū.

ʻOiai ka hoʻohālikelike hoʻohālikelike, pili pono kēia lāʻau lapaʻau i ka pancreas, ʻo ia ka mea o ka pōkole i ka synthesis o kāu insulin ponoʻī. Hoʻolaha wale ʻia ʻo PSM inā ʻike maikaʻi ʻole ka metformin a i ʻole ka nui o kona nui kiʻekiʻe no ka glycemia maʻamau. Ma ke ʻano he kānāwai, he hoʻonaninua loa kēia o ka maʻi maʻi maʻi, a i kahi maʻi lōʻihi.

ʻO Amaril a ʻo Yanumet

ʻO Yanumet, e like me Amaryl, pili pono i nā kiʻekiʻe o ka insulin a me ka pale ʻana i ka insulin. ʻOkoʻa nā lāʻau'ōnaehana i ka ʻoihana o ka hana a me ka ʻōnaehana kemika, no laila hiki ke lawe pū ʻia. ʻO Yanumet kahi lāʻau lapaʻau hou hou, no laila e kūʻai ʻia mai ka 1800 rubles. no ka ami uuku. Ma Lūkia, ua hoʻopaʻa inoa ʻia kona mauʻatikala: Combogliz a me Velmetia, ʻaʻohe haʻahaʻa ma mua o ka mea maʻamau.

I ka nui o nā hihia, hiki ke loaʻa i ka uku hoʻolaʻa ma ka hui ʻana o ka metformin maʻalahi, kaʻai, ka hoʻolaʻa, hoʻomaʻamaʻa, manawa i kekahi manawa ke koi nei ka maʻi PSM. Pono ke kūʻai wale ʻo Yanumet inā ʻaʻole nui ia ke kumukūʻai o ke kālā.

Amaril M

ʻO ka hoʻokō ʻole ʻana e nā maʻi maʻi me ka ʻoihana i kuhikuhi ʻia i ke kumu nui no ka hoʻēmi ʻana o ka maʻi maʻi. ʻO ka hōʻoluʻolu ʻana o ka lāʻau lapaʻau lāʻau no kekahi maʻi maʻi mau e hoʻomaikaʻi mau i kona mau hopena, no laila, no nā mea maʻi koho, ʻoi aku ka makemake o nā lāʻau lapaʻau. Loaʻa i ka Amaryl M ka maʻamau o ka hui like ʻole o ka wai hoʻohaʻahaʻa i ka hoʻōla: metformin a me PSM. Aia kēlā me kēia papa i 500 mg o ka metformin a me 2 mg o ka glimepiride.

ʻAʻole hiki ke hoʻoponopono kaulike i nā mea ikaika i ka papa hoʻokahi no nā maʻi like ʻole. Ma ke kikowaena o ka maʻi maʻi, ʻoi aku ka nui o ka metformin, he emi iho ka glimepiride. ʻAʻole iʻoi aku ma mua o 1000 mg o metformin e ʻae ʻia i ka manawa, nā mea maʻi e loaʻa ana i kahi maʻi koʻikoʻi e inu iā Amaril M ʻekolu mau manawa i ka lā. No ke koho ʻana i ka nui o ka wai, pono ʻia no nā maʻi aʻo ʻia e lawe iā Amaril e hoʻokaʻawale ana i ka ʻaina kakahiaka a me Glucofage ʻekolu o ka lā.

Hoike Mai

Hōʻike ʻia e Maxim, 56 makahiki. ^ E Ha yM. Ua kauoha ʻia ʻo Amaril i koʻu makuahine ma mua o Glibenclamide e hoʻopau i ka hypoglycemia pinepine. ʻOi aku ka palaki haʻahaʻa ma ka nui o ka hilo, ʻaʻole nā ​​mea liʻiliʻi wale nō i nā hopena i nā ʻōlelo aʻoaʻo. I kēia manawa e lawe iā ia i 3 mg, paʻa ka paʻakai i ka 7-8. Makau mākou e hoʻēmi me ia, ʻoiai he 80 mau makahiki ʻo ka makuahine, ʻaʻole ʻo ia e ʻike mau i nā hōʻailona o ka hypoglycemia.
Hana ʻia e Elena, 44 makahiki. ^ E Ha yM. Ua ʻōmole ʻo Amaril e kahi endocrinologist a ua ao mai iaʻu e lawe i ka lāʻau lapaʻau Kelemania, ʻaʻole i nā mea kikowaena maʻalahi. E mālama aku, ua kūʻai au i ka ʻāpana nui, no laila ʻo ka uku o nā huahelu o ka papa ʻaina 1 ma lalo. Loaʻa iaʻu i nā paʻu piha no 3 mau mahina. He liʻiliʻi nā papa papa, ʻōmaʻomaʻo, o kahi ʻano ʻē ʻole. ʻO ka molumela, he mea maʻalahi ia e hoʻokaʻawale iā ia i nā māhele. ʻO nā ʻōkuhi no ka hoʻohana ʻana he nui wale nō - 4 mau ʻaoʻao i nā leka liʻiliʻi. ʻO ke kaona palaoa i kēia manawa 5.7, kahi kiko o 2 mg.
Hōʻike ʻia e Catherine, 51. ^ E Ha yM. Ua maʻi wau i ka maʻi maʻi no nā makahiki 15, i kēlā manawa ua hoʻololi au i nā lāʻau lapaʻau ma kahi o ka umi. ʻĀnō nei wau e lawe nei i nā papa Amaryl wale nō a me Kolya insulin Protafan. Ua kāpae ʻia ʻo Metformin, ʻōlelo lākou he mea ʻole, mai ka inehina wikiwiki oʻu ʻike ʻino. ʻO ka Sugar, ʻoiaʻiʻo, ʻaʻole maikaʻi loa, akā aia ka liʻiliʻi ma nā hoʻopiʻi.
ʻIke ʻia e Alexander, 39 makahiki. ^ E Ha yM. Ua koho ʻia nā lāʻau hoʻomohala haʻahaʻa noʻu i ka manawa lōʻihi a paʻakikī. ʻAʻole i hele a Metformin i kekahi ʻano, ʻaʻole hiki ke haʻalele i ka hopena i nā hopena ʻokoʻa. Ma muli o kēia, ua noho mākou ma Amaril a me Glukobay. Lawe maikaʻi lākou i ke kō, ua hiki ke hypoglycemia wale nō inā ʻaʻole ʻoe e ʻai i ka manawa. He kūpono loa nā mea āpau a hiki ke wānana, ʻaʻohe makaʻu e ala i ke kakahiaka. ʻO ka manawa hoʻokahi, ma mua o Amaril, hāʻawi lākou i ka Lūkini Glimepirid Lūkini. ʻAʻole au i ʻike i kekahi mau mea ʻē aʻe, koe wale nō ka nani o ka pale.

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