ʻO Yanumet kahi hui o ka lāʻau hypoglycemic waha i hoʻohana ʻia i ka mālamaʻana i ka mellitus non-insulin-dependence. ʻO ka lawe ʻana i ka lāʻau lapaʻau e kōkua i ka mālama ʻana i ke kaʻe o ka glucose koko maʻamau, keʻae i ka holomua o ka maʻi a hoʻomaikaʻi i ke ʻano o ke ola no nā maʻi.
Inoa Kūʻai ʻole honua
Metformin + Sitagliptin.
ʻO Yanumet kahi hui o ka lāʻau hypoglycemic waha i hoʻohana ʻia i ka mālamaʻana i ka mellitus non-insulin-dependence.
ATX
A10BD07.
E hoʻokuʻu i nā palapala a me ka ʻano
Loaʻa ia ka lāʻau lapaʻau ma ke ʻano o nā papa oblong me kahi papa biconvex, i uhi ʻia me ke kiʻi enteric o ke aniani ʻulaʻula, a ʻulaʻula a i ʻole ʻulaʻula (hilinaʻi i nā kākā). Hoʻopaʻa ʻia ka lālani i nā pūʻulu blister o 14 mau ʻāpana. Aia kahi pepa o ka pepa mānoanoa mai ka 1 a hiki i ka 7 mau kāwili.
ʻO nā mea hana a Yanumet kahi sitagliptin ma ke ʻano o ka phosphate monohydrate a me ka metformin hydrochloride. ʻO nā mea o kahi sitagliptin i ka hoʻomākaukau hana mau - like me 50 mg. ʻO ka hapa iki o ka metformin hydrochloride e loli a 500, 850 a i ʻole 1000 mg i ka papa pā.
E like me nā mea kōkua, aia ʻo Yanumet ka lauryl sulfate a me ka sodium stearyl fumarate, povidone a me MCC. Hana ʻia ka papa pālani mai ka macrogol 3350, polyvinyl ka ʻona, titanium dioxide, ʻulaʻula a me ka ʻio hāhi kahe.
Hoʻopaʻa ʻia ka lālani i nā pūʻulu blister o 14 mau ʻāpana.
Ka hana lāʻau lapaʻau
ʻO ka lāʻau lapaʻau ka mea hoʻohui hui nona nā mea ikaika e hoʻohui i ka hopena hypoglycemic hoʻohui (kōkua) me ke kōkua ʻana i nā mea maʻi e pili ana i ka maʻi diabetes mellitus maʻamau.
ʻO Sitagliptin, kahi ʻāpana o ka lāʻau lapaʻau, he melepidyl peptidase-4 sambali ākea. Ke lawe ʻia i ka waha, hoʻonui i ka ʻike o ka ponaide-like peptide-1 a me ka peptide insulin-e hilinaʻi nei i ka glucose - nā hormones e hoʻonui i ka hana o ka insulin a hoʻonui i kāna nīnū i nā cell pancreatic ma o 2-3 mau manawa. Hāʻawi ka Sitagliptin iā ʻoe e mālama i ke kōpaʻa koko gula maʻamau i ke ao a pale i ka hoʻomohala ʻana o ka glycemia ma mua o ka ʻaina kakahiaka a ma hope o ka ʻai ʻana.
Hoʻohana ʻia ka hana o sitagliptin e ka metformin - he ʻano hypoglycemic pili i ka biguanides, kahi e hoʻemi ana i ke kahe o ke kō i loko o ke koko ma o ka hoʻokuʻi ʻana i ka 1/3 ke kaʻina o ka hana glucose i loko o ka ate. Eia kekahi, i ka wā e lawe ai i ka metformin i nā mea maʻi me ka diabetes type 2, aia ke emi ʻana i ka lalau ʻana o ka glucose mai ka digestive tract, kahi nui o ka hoʻonaninani ʻana i nā kinina a me ka hoʻonui ʻana o ke ʻano o ka hoʻowalewā momona o ka momona.
Lapaʻau lāʻau
ʻO ka paona plasma kiʻekiʻe loa o ka sitagliptin i ʻike ʻia i nā hola 1-4 ma hope o ka hoʻomoʻa waha ʻana i kekahi maʻa hoʻokahi, metformin - ma hope o 2 mau hola. ʻO ka bioavailability o nā mea hana ikaika ke hoʻohana nei iā Yanumet ma kahi ʻōpū ʻole he 87% a 50-60%, kēlā.
ʻO ka hoʻohana ʻana o ka sitagliptin ma hope o ka ʻaina ʻaʻole i hoʻopilikia i ka hana ʻia ʻana mai ka papa hana ʻana o ka pā. ʻO ka hoʻohana like ʻana o ka metformin me ka meaʻai e hoʻemi ana i ka helu o ka hoʻoulu ʻana a hōʻemi i ka hoʻoliʻelima ʻana i ka plasma e 40%.
Ka hele ʻana o ka sitagliptin e hele nui me ka urine. ʻO kahi ʻāpana liʻiliʻi o ia mea (ma kahi o 13%) e waiho i ke kino me nā mea i hoʻopili i ka ʻōpū. Hoʻopau piha ʻia ʻo Metformin e nā keiki.
Hoʻopau piha ʻia ʻo Metformin e nā keiki.
Nā hōʻailona no ka hoʻohana ʻana
Ua kuhikuhi ʻia kahi lāʻau lapaʻau no ka maʻi maʻamau o ka lā 2. Hōʻike ʻia ka hoʻohui ʻia ʻana o ka meaʻai a me ka hoʻomaʻamaʻa ʻana i nā maʻi i:
- ʻaʻole hiki ke kāohi i nā pae glucose me nā kiʻekiʻe kiʻekiʻe o ka metformin;
- Ua lawe ʻē ʻia nā lāʻau lapaʻau e pili ana i nā hana ikaika e kūkulu ʻia ai ka Yanumet, a me ka hopena ua lawe ʻia ka hopena maikaʻi;
- pono hui e hui pū ai me nā derivatives sulfonylurea, nā PPARγ agonists, a i ʻole insulin, ʻoiai ke lawe ʻana i ka metformin i hui pū ʻia me nā lāʻau i kākau inoa ʻaʻole ia e ʻae i ka pono o ka mana o ka glycemia.
Nā Hoʻohui
ʻAʻole hoʻohana ʻia ka lāʻau lapaʻau i ka mālama ʻana i nā maʻi i loaʻa i kēia mau maʻi a i ʻole nā ʻano:
- ʻ Ilelo diabetes Mellitus;
- ketoacidosis, hele pū me kahi coma maʻi maʻi ʻole a ʻole ia;
- lactic acidosis;
- hana aho pili ole;
- pilikia ʻole, ma kahi hana hoʻopihapiha ma lalo o 60 ml mau minuke;
- hana huehue o ke kino;
- nā papa maʻi koʻikoʻi o nā hele mai ka huakaʻi maʻi;
- haunaele kūlana;
- loea me ka iodine e loaʻa nā mea kūlike;
- nā ala e alakaʻi ai i kahi haʻahaʻa haʻahaʻa haʻahaʻa o ke kino (ka palaualelo o ka naʻau, ka myocardial infarction, ka ʻole ʻana o ka ea, a pēlā aku);
- ke kaumaha o ka kaumaha me ka haʻahaʻa-calorieʻaiʻai (a hiki i 1 tausani kcal i ka lā);
- waiʻona wai;
- mea ʻona make kino;
- lactation
- hapai
- makahiki liʻiliʻi;
- ka mālama ʻana o kēlā me kēia ma nā ʻāpana i kau ʻia i ka hoʻonohonoho ʻana o nā papa.
Me ka mālama pono
Ke hoʻohana nei iā Yanumet, e makaʻala e hoʻomaʻamaʻa e ka poʻe elemakule a me kēlā mau mea e hōʻeha nei i ka hoʻomaʻamaʻa ʻana o ka pale.
Pehea e lawe ai iā Yanumet
Hoʻomaʻa ʻia ka lāʻau lapa ʻelua ʻelua i ka lā me ka meaʻai, holoi ʻia me nā wai o ka wai o ka wai. No ka hoʻēmi ʻana i ka hopena o ka hoʻopiʻi ʻana mai ka digestive tract, hoʻomaka ka mālama ʻana me ka liʻiliʻi liʻiliʻi, e hoʻonui pinepine a hiki i ka hopena therapeutic makemake ʻia.
Lawe i ka lāʻau lapaʻau no ka maʻi maʻi maʻi
Koho ʻia ka ʻano o Yanumet no kēlā me kēia maʻi i kēlā me kēia kanaka, e noʻonoʻo ana i ka hopena o ka lāʻau lapaʻau a me ka hiki ʻana o ka lāʻau lapaʻau. ʻAʻole pono ka nui o ka nui o ka lā ma mua o 100 mg.
Nā hopena hopena o Yanumet
I ka wā e lawe ai i ka lāʻau lapaʻau, hiki i ka mea maʻi ke hōʻeha i nā hopena maikaʻi ʻole e hoʻonāukiuki ʻia e ka sitagliptin a me ka metformin. Inā hele lākou, pono ia e pale iki aku i ka lāʻau hou a kipa i ke kauka i ka hiki koke.
I ka hihia o nā hopena hopena, pono e pale i ka lāʻau hou a kipa aku i ke kauka i ka hiki koke.
ʻŌpala Gastrointestinal
ʻO nā hopena ʻino loa mai ka ʻōnaehana o ka digestive e ʻike pinepine ʻia i ka hoʻomaka mua o ka maʻi. Hoʻopili kēia i ka ʻeha ma ka gastrointestinal tract kiʻekiʻe, nausea, ka luaʻi, ka hoʻonui ʻana i ka mīkini i loko o nā ʻōpū, ʻīwī, a maʻi constipation. ʻO ka lawe ʻana i nā paila me ka meaʻai e hiki ke hōʻemi i kā lākou hopena maikaʻi ʻole ma ka papa hana o ka kūnaʻi ʻana.
I ka poʻe maʻi e loaʻa ana ka mālama ʻana me Yanumet, ʻo ka hoʻomohala ʻana o ka pancreatitis (hemorrhagic a necrotizing paha), kahi e hiki ai ke make, ʻaʻole i haʻalele ʻia.
Mai ka ʻaoʻao o ka metabolism
Inā koho ʻole ʻia ka dosage, hiki i ka mea maʻi ke loaʻa i ka hypoglycemia, kahi i ka emi nui o ke kō o ke koko. ʻO ka manawa, ka lawe ʻana i ka lāʻau lapaʻau hiki ke alakaʻi i ka lactic acidosis, ka mea e hōʻike ana iā ia iho i loko o ke ʻano o ka hoʻemi ʻana o ke kaomi a me ke ʻano o ke kino, ʻeha ma ka ʻōpū a me nā ʻōpū, nā maʻi ʻālunu, nāwaliwali a me ka hiamoe.
Ma ka ʻāpana o ka ʻili
I nā hihia kaʻawale, i nā mea maʻi e lawe ana i ka lāʻau lapaʻau hypoglycemic, hōʻike ka poʻe loea i ka vasculitis ʻili, pemphigoid bullous, toxic epidermal necrolysis.
Mai ka pūnaehana cardiovascular
Hoʻomaʻamaʻa maikaʻi ʻia ka lāʻau e nā poʻe e loaʻa ana i nā maʻi o ka puʻuwai a me nā kīʻaha koko. I kekahi manawa, ʻike paha lākou i ka emi ʻana o ka puʻuwai puʻuwai, e ala ana ma ka hopena o ka maʻi lactic acidosis.
Hoʻomaʻamaʻa maikaʻi ʻia ka lāʻau e nā poʻe e loaʻa ana i nā maʻi o ka puʻuwai a me nā kīʻaha koko.
Allergies
Me ka hoʻomanawanui ʻole o nā kūloko i nā mea i kūkulu ʻia i ka lāʻau lapaʻau, hiki i ke kanaka ke hoʻomohala i nā hopena kūlohelohe i ke ʻano o ka urticaria, kaʻeha a me ka rashes ma ka ʻili. I ka wā o ka mālama ʻana me Yanumet, ʻaʻole hiki ke ʻae ʻia ka hopena o ka edema o ka ʻili, ka membrane mucous a me ka kiko o subcutaneous, ʻo ia hoʻi ka mea e ola nei.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
Hiki i ka lāʻau lapaʻau ke hōʻeha i ka hiamoe, no laila i ka manawa o kāna hoʻokele ʻana e pono ai ke hōʻole i ka kaʻa o ka kaʻa a hana me nā hana hoʻokūkū ʻē aʻe.
Nā ʻōlelo kikoʻī
I ka wā o ka mālama ʻana me Yanumet, pono ka poʻe maʻi e hahai i ka papaʻai me ka kahele like ʻana o nā hāmeʻakāka i ka lā a me ka ʻōnaehana kaohi ʻana i ka metabolism kila i loko o ke kino.
Hoʻohana i ka wā hāpai a me ka lactation
ʻAʻole ʻawaʻī ka lāʻau lapaʻau i ka wā e lawe ana i kahi keiki, ʻo ka ʻike ma o kona palekana i kēia manawa ʻaʻole ʻike. Inā he wahine hāpai i ka mālama ʻana iā Yanumet a lilo paha i hoʻolālā, e pono hoʻi iā ia e kāpae i ka lawe ʻana i ka insulin.
ʻAʻohe kūpono o ka hoʻohana ʻana i ka lāʻau me ka umauma.
ʻAʻohe kūpono o ka hoʻohana ʻana i ka lāʻau me ka umauma.
Koho o Yanumet i na keiki
ʻO nā noiʻi e hōʻoia ana i ka palekana o ka lāʻau lapaʻau i nā keiki a me nā ʻōpio ʻaʻole i lawe ʻia, no laila, ʻaʻole pono e kuhikuhi ʻia i nā poʻe maʻi ma lalo o ka makahiki o 18.
Hoʻohana i ka wā kahiko
No ka mea ua hoʻōla ʻia nā mea ikaika o Yanumet i loko o ka mimi, a ma ka wā kahiko, ua emi ka hana excretory o nā pēpē, pono e kuhikuhi ʻia ka lāʻau lapaʻau i nā kānaka ma mua o 60 mau makahiki he nui.
Ke noi no ka hana renal haukapole
Hoʻokomo ʻia ka lāʻau i nā maʻi e hōʻeha ʻia ana i ke ʻano paʻakikī a hōʻemi paha o ka maikaʻi ʻole. ʻO nā poʻe me ka hoʻemi ʻana o ke kaupaʻa e hana i nā lāʻau lapaʻau ma lalo o ka mālama ʻana o kahi loea.
Hoʻohana no ka hana lawelawe lēwa
Kuhi ʻia ke koho ʻia.
ʻO ka poʻe maʻi me ka hana lēʻaleʻa pale ʻole i kuhikuhi ʻia i nā lāʻau lapaʻau.
ʻOukiā o Yanumet
Inā nui ka nui o kēia maʻa, hiki i ka mea hoʻomohala ke hoʻomohala i ka waikawa lactic. No ka hoʻokō ʻana i ke ʻano, hana ʻia ʻo ia i ke ʻano maʻi lapaʻau i hui pū me nā hana e hoʻomaʻemaʻe i ka hoʻomaʻemaʻe ʻana i ke koko.
Hoʻopili pū me nā lāʻau ʻē aʻe
ʻO ka hui pū ʻana o ka lāʻau me nā diuretics, glucagon, contraceptives waha, phenothiazines, corticosteroids, isoniazid, calcium antagonists, nicotinic acid a me ka hormone thyroid alakaʻi i kahi nāwaliwali o kāna hana.
Hoʻonui ka hopena hypoglycemic o ka lāʻau ke hoʻohana pū ia me nā lāʻau anti-inflammatory non-steroidal, MAO a me ACE inhibitors, insulin, sulfonylurea, oxytetracycline, clofibrate, acarbose, beta-blockers a me cyclophosphamide.
Hoʻolaha ka waipuna
Lā ʻia ka inu ʻawaʻī i ka wā o ka mālama ʻana me Yanumet.
Nā kuʻina
ʻO ka hōʻailona kikoʻī o ka lāʻau lapaʻau ka Valmetia. ʻO kēia lāʻau lapaʻau e hana ʻia i ka puka papa a he ʻano mana a me ka dosage e like me Yanumet. Eia kekahi, ʻo ka lāʻau lapaʻau ke koho ikaika aku - Yanumet Long, aia ka 100 mg o sitagliptin.
Ma ka haʻalele ʻana i kahi hopena therapeutic mai Yanumet, hiki i ke kauka ke kuhikuhi i nā kumuhana hypoglycemic i ka mea maʻi, i hui pū ai ka metformin me nā mea maʻi hypoglycemic ʻē aʻe. Aia kēia mau lāʻau lapaʻau:
- Avandamet;
- Amaryl M;
- Douglimax;
- Galvus;
- Vokanamet;
- ʻO nā Glucovans, etc.
Waihue huaʻōlelo waiho nā huaʻōlelo
Ma ke alo o kahi papa inoa.
Hiki iaʻu ke kūʻai me ke kī ʻole
Hiki iā ʻoe ke kūʻai i ka lāʻau me ke kumu kūʻai ole aia i loko o nā mea lapaʻau pūnaewele.
Kumukuai no Yanumet
Kālai ʻia ke kumukūʻai o ka lāʻau lapaʻau ma muli o kāna maʻi a me ka helu o nā papa i loko o kahi pā. I Rusia, hiki ke kūʻai ʻia no 300-4250 mau rubles.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Pono ʻia ka lāʻau e mālama ʻia i kahi wahi i pale ʻia mai ka lā a i hiki ʻole i nā keiki liʻiliʻi. ʻAʻole pono nā kahu mālama i nā papa ma mua o + 25 ° C.
I loko o nā lāʻauʻai, hiki ke kūʻai wale ʻia ka lāʻau lapaʻau me kahi papa inoa.
ʻO ka lā kau
24 mahina mai ka lā o ka hana.
Mea hana
ʻOihana lāʻau lapaʻau Merck Sharp & Dohme B.V. (Netherlands).
ʻLelo a nā kauka e pili ana iā Yanumet
Sergey, 47 makahiki, endocrinologist, Vologda
No ka poʻe maʻi me ka non-insulin-dependant dependence, kuhikuhi pinepine wau i kēia lāʻau lapaʻau, ʻoiai ua hōʻoia ʻia kā kona hopena i kēia lā. Kāohi ʻo ia i ka glucose a hoʻomaʻamaʻa ʻaʻole ia i hopena i ka hopena, ʻoiai me ka hoʻomohala lōʻihi.
ʻO Anna Anatolyevna, he 53, mau makahiki endocrinologist, Moscow
Manaʻo wau i ka mālama ʻana me Janumet no nā poʻe maʻi hiki ʻole i hiki ke hoʻololi i kā lākou koko koko me Metformin wale nō. ʻO ka hoʻohui paʻakikī o ka lāʻau lapaʻau e kōkua i ka maikaʻi o ka hoʻomohala ʻana i nā ʻōuli glucose. Ke makaʻu nei kekahi poʻe maʻi e lawe i ka lāʻau lapaʻau ma muli o ka loaʻa mai o ka hypoglycemia, akā ua hōʻike mua nā noiʻi like ʻole ka like o ka mea e hiki mai ana ma waena o ka poʻe i loaʻa i nā paila a me ka placebo. A ʻo kēia ke ʻano ka hopena o ka lāʻau lapaʻau ma ka hoʻomohala ʻana i ka maʻi hypoglycemic syndrome. ʻO ka mea nui, ʻo ke koho i ke ʻano kūpono.
Pono e mālama ʻia ka lāʻau lapaʻau i nā kānaka ma luna o 60 mau makahiki he nui.
Nā Hōʻike Hoʻomaʻi
Lyudmila, 37 makahiki, Kemerovo
Ua hoʻomaka wau e hana me Janomat no hoʻokahi makahiki. Lawe au i ka palena haʻahaʻa o 50/500 mg i ke kakahiaka a me ke ahiahi. No nā mahina 3 mua o ka mālama ʻana, ʻaʻole hiki wale nō ke kaʻi aku i ka maʻi ma lalo o ka kaohi, akā, e nalowale hoʻi he 12 kg o ka nui o ke kaumaha. Hoʻohui wau i ka lāʻau lapaʻau me ka meaʻai a me ka hana kino. I kēia manawa uaʻoi aku ka maikaʻi ma mua o ka mālama ʻana.
Nikolay, 61 makahiki, Penza
Ua hoʻomaʻa ʻo ia no ka inu ʻana iā Metformin no ka maʻi diabetes, akā ua lohi iki ʻo ia i ke kōkua ʻana. Ua ʻōlelo ka poʻe endocrinologist e mālama iā Yanumet a ʻōlelo aku ʻo ia nei ka lāʻau lapaʻau ʻoi aku ka ikaika ikaika o ka mea aʻu i lawe ai ma mua. Ua lawe wau iā ia i mau mahina 2 mau, akā ua hoʻonui ʻia ke kō. ʻAʻole wau i ʻike i kahi hopena maikaʻi mai ka mālama ʻana.
