ʻO ka hoʻohanaʻana i ka inhibitor protease no ka mālamaʻana o pancreas

Me ka pancreatitis, ʻo ka hoʻolaʻaʻana o nā proteases e alakaʻi i ka maʻi o ke kino a me ka hoʻomohala ʻana o nā pūnaewele necrotic.

I mea e pale ai i nā kaʻina holokeʻo, ua kuhikuhi ka poʻe loea i nā Contrical, Trasilol, Gordoks a me Antagozan. ʻO ka hoʻohana ʻana i kēia mau lāʻau lapaʻau no ka hoʻokō intravenous mea nui loa i ka lā mua o ke pancreatitis aila.

Nā ʻano o Enzymes pancreatic

ʻO ka hana nui o ka pancreas ke hana i ka hana endocrine (i loko) a me nā exocrine (waho). Hoʻokomo ka hana endocrine i ka hana ʻana i nā hormones - insulin, e hoʻohaʻahaʻa i ka glucose, a me ka glucagon, e hoʻoikaika ana i ka ka haʻalele ʻana o nā glucose i loko o ka ate.

ʻO ka hana exocrine o ka pancreas ka hana ʻana i nā enzyme kūikawā (enzymes) no ka hoʻokaʻawale ʻana i nā meaʻai. Pono e hoʻokaʻawale i nā pūʻulu - lipolytic, amylolytic a me proteolytic enzim. E noʻonoʻo pono i kā mākou kikoʻī o kēlā me kēia mahele.

Nā ʻōmaʻomaʻo lipolytic. No kēia hui ke kuleana o ka haki ʻana i nā momona i nā momona momona a me nā glycerol. ʻO Prolipase kahi enzyme lipase kaheʻe ʻole, i ka wā e komo ai i ka duodenum, hui pū me ka colipase.

Hoʻohana ʻia ka lipase me ka nui o nā paʻakai bile a me ka trypsin. Hoʻomaʻamaʻa ke kahe ʻana o nā māhele lipolytic i nā hola 7-14. Kuhi ka glomeruli Renal no kā lākou kānana: hoʻolaha lākou i ka hoʻopili ʻana o ka lipase i ka hoʻopili ʻana o nā mea kiko, no laila ʻaʻole i loaʻa nā māhele o nā lipolytic i ka urine. Hoʻonui ʻia nā mea like e like me nā lipase e ka ʻāʻī, nā ʻōpū a me nā ʻāpana.

Nā ʻōmole amylolytic. Nui nā ʻanoʻokoʻa - alpha, beta a me gamma amylase. Ua kapa ʻia kēia ʻano o nā enzyme i ke ʻano aliʻi. I loko o ke kaʻina hana ʻana, hoʻopili wale ʻia ʻo alpha-amylase.

Hoʻokuʻu ʻia kekahi i nā mea liʻiliʻi na nā kalepona salivary, ʻoi loa ke kipi ʻana i ka meaʻai. No laila, manaʻo mākou i kahi mea momona a ʻoi hoʻi ka ʻuala i nā meaʻai-ʻai mea i waiho ʻia ʻai - nā māla a i ʻole a i kaleta ʻia. Mahalo i amylase, ke kaʻina o ka assimilation o ke kō a me nā mea paʻakikī ʻē aʻe e maʻalahi.

Nā kinipōpō protein. ʻO ka hana nui o kēia hui ka wāwahi ʻana i nā protein. Hoʻopuka ka huina protein protocol i ka wāwahi o ka waikawa amino i paʻa i nā peptides a me nā protein. ʻElua ʻanoʻokoʻa o ka protease ma ka wai pancreatic:

1. ʻO Peptidase, a i ʻole exopeptidase, kuleana no ka hydrolysis o nā pulu koʻo o nā peptides.
2. ʻO ka protein, a i ʻole endopeptidase e wāwahi i ka hoʻohui kino o nā peptides.

No laila, lipase, amylase a me ka protease ka hua ʻana i ka wai pancreatic, kahi, i ka wā e komo ana i ka duodenum, e wāwahi ʻo ia i nā molekiola paʻakikī i loko o nā mea maʻalahi maʻalahi.

Nā kumu a me nā hōʻailona o ka pancreatitis

I loko o kahi kanaka olakino, hoʻōla ʻia ka hoʻouluulu o nā enzyme pancreatic i ka duodenum.

Inā he hana ia o ka amylase, hoʻomaka ka protease a me ka lipase i ka pancreas ponoʻī, hiki iā mākou ke kamaʻilio e pili ana i ka hāʻule ʻole o ka huelo.

Hoʻomaopopo ka pancreatitis me kahi paʻakikī o nā syndromes a me nā maʻi i hoʻopiʻi ʻia me ka hoʻōla o nā huina i loko o ka palaki, ka mea e alakaʻi ai i ke kaʻina o ka "pale kūʻokoʻa". I ka hopena, ʻaʻole lākou e komo i ka duodenum, a hoʻopau ʻia ka hoʻoneʻe ʻana.

Aia kekahi mau kumu e alakaʻi ai i kēia ʻano ʻōiwi:

• ka inu pinepine ana
• hiki ʻole ke hahai i kahi meaʻai kūpono;
• kaʻai nui ʻana i nā meaʻai a me nā momona;
• kaʻai ʻana i ka mea ʻai maikaʻi ma hope o ka ʻaina kūpono ʻole a ka wikiwiki paha;
• ka hana ole ana i kekahi o na laau maiau;
• pilikia hōʻeha o ka hoʻopili ʻana;
• kalaka o kahi ʻano maʻi.

Me ka hoʻōlaʻana o nā huina i ka pancreas, kū ka huhū: ua nui ka nui, a loaʻa nā wahi necrotic. ʻAʻole hiki ke ʻano he ʻano no ka manawa like me ka manawa, aia kekahi hewaʻole o ke keʻakeʻa gastrointestinal.

Me ka nele o nā enzyme pancreatic i loko o ka duodenum a me ka mumū o nā pancreas, ʻike ʻia nā hōʻailona like ʻole:

1. ʻEha i ka hypochondrium hema, pinepine kahi ʻano shingles.
2. ʻO ka hōʻemi nui loa i ka maʻi kīnā, ka maʻi maʻamau a me ka nāwaliwali.
3. ʻO ka maʻi Dyspeptic - bloating, nausea a luaʻi paha, nele i ka makemake, ka lāʻau staired.

Hiki i nā ʻōmole o ke maʻi ke ʻano ma ka hemahema o kekahi enzim:

• ʻO ka hapa nui o Amylase e alakaʻi i ka maʻi puhaka, ka nui o ka hōʻemi, ka nui o ke kaumaha. Loaʻa nā mīkī me ka waiū, ʻaila unigested o ka meaʻai ma loko.
• ʻAʻole ka hapa o ka lipase e wāwahi i nā momona nā kumu steatorrhea - hoʻonui iki i ka nui o ka momona i ka papa. Me ka pancreatitis, e ʻeleʻele a ʻulaʻula paha ka neʻe ʻana i loko o ka iwi ʻolipani, ʻike ʻia kahi mālohu o ka māpala i loko o lākou.
• Me ka nele o ka protease, ua loaʻa nā ʻōmole protein undigested i loaʻa i nā feces. ʻO kahi hiʻohiʻona maʻamau ka hoʻomohalaʻana i ka anemia.

Inā ʻike kekahi i kēlā mau ʻōuli, pono ʻo ia e ʻimi i ke kōkua olakino i ka hiki. E kuhikuhi ke kauka i nā hana o nā hoʻokolohua a me nā pono kūpono.

Nā mea hoʻomaʻi Enzyme pancreatic maoli

Hoʻokomo wale ke kino i nā mea enzymatic i komo i ka hoʻopau ʻana o nā molekō paʻakikī, akā ke pale pū kekahi i ka mea paʻa pancreatic, i.e. nā mea e pale ai i ka hoʻoulu ʻana o ka wai pancreatic.

Hoʻopili ka poli o ka maikaʻi ma ka pancreatic polypeptide (PPP), YY peptide, somatostatin, pancreatic glucagon, pancreastatin a me neuropeptides.

ʻO nā mokupuni o Langerhans, i loaʻa nui i ka lālaki o ka pancreas, e hoʻoulu i kahi hormone kūikawā, ʻo PPP, ka mea i pale i ka hana o ka pancreatic wai, nā enzyme a me nā bicarbonates. Mālama pū kekahi i ka hana o acetylcholine.

Hoʻonui ʻia ka mea huna o ka PPP i kēlā mau kūlana:

1. me ka mea noʻonoʻo e ʻai nei a i ʻole ka ʻai;
2. ma hope o ka hoʻoulu ʻana o ka nerve vagus;
3. me ka acidification o ka duodenum;
4. i ka wā e hoʻolaha ai i ka gastrin a me ka gastrin-hoʻokuʻu i ka peptide;
5. i ka wā e hōʻike aku ai i ka pilikino, cholecystokinin a me VIP.

Hoʻopuka ka distum ileum a me kahi ākea i ka peptide YY i ka wā e komo ai nā momona i ka ʻalihi. Kōkua kēia peptide i ka hoʻēmi ʻana i ka hiki o ka kelepona i nā hopena o ka cholecystokinin a me nā mea huna.

ʻO nā cell pancreatic D a me ka membrane mucous o ka digestive tract e loaʻa ana i ka somatostatin. Hoʻopili kēia hormonale i ka hana o nā enzyme a me nā bicarbonates. Hoʻokomo ka pūnaehana autonomic i ka hana o somatostatin, ma hope koke iho mai nā momona a me nā waikawa amino mai ka meaʻai.

ʻO nā inhibitoratic pancreatic kekahi e hōʻike ʻia e nā hormones like:

• ʻO ka glucagon pancreatic, kahi e kāpae ai i nā hana o nā wai, nā bicarbonates a me nā enzymes.
• ʻO ka pancreatin, ka pale ʻana i ka hoʻokuʻu ʻana o ka acetylcholine. Hana ʻia ia ma nā hopena efferent o ka wahī waha.
• ʻO ka neuropeptides, ka mea i loaʻa i ka peptide e pili ana i ka calcitonin (hoʻoulu i ka somatostatin) a me nā enkephalins (e hōʻemi i ka hana o acetylcholine).

Me nā hana ʻino i loko o ka hoʻopīpī, hiki ke hoʻōla i ka hoʻoweliweli ʻana o ka pancreatic enzyme, no laila, pono e lawe ʻia nā lāʻau lapaʻau.

Nā lula o ka mālamaʻana no ka maʻi pancreatitis

ʻO nā mea nui ʻelua o ka mālama ola no ka maʻi maʻi he meaʻai a me ka lāʻau lapaʻau. Hoʻokumu ʻia ka regimen lapaʻa pilikino e pili ana i ka nui o ka maʻi a me ka hana ʻino i ka pancreas.

Hoʻokumu ʻia ka meaʻai kūikawā no ka pancreatitis ma ka helu helu 5 e like me ke Pevzner. Hoʻopau i ka hoʻohana nui ʻana i nā mea momona a me nā momona, a ke manaʻo nei nō hoʻi e ʻai i ka ʻai o ka protein.

Me ka hoʻomaka ʻana o ka pancreatitis kūlohelohe, ua hoʻokaʻawale ʻia nā lā 3-4 o ka hoʻokē ʻai. I kēia manawa, pono ʻoe e hōʻole loa i ka ʻai a inu i nā wai hoʻoluʻu mahana, no ka laʻana, ʻo Borjomi.

Ma hope o ka pololi me ka pancreatitis, ua hoʻokomo ʻia nā meaʻai i ka mālama ʻia i loko o ka meaʻai i lawe ʻole i ke kaomi ʻana o ka ʻōpala. ʻO nā mea maʻi me ka pancreatitis e ʻae ʻia e:

• ke ʻano ʻai o nā ʻai a me ka iʻa;
• mau mea ʻupena a inaina ʻia i nā kalapu;
• berena a inehinei
• nā huahana wai kīnā;
• nā huaʻai nui, nā mea kanu a me nā lau;
• cereals i loko o ka wai a i ʻole skim waiū;
• hua ma nā helu ʻeha;
• rosehip hupa, meli a iʻa paha (palena).

Me ka hoʻowalewale o ka pancreas, pono ia e hōʻole i ka meaʻai e hoʻonāukiuki i ke kaʻina hana ʻana:

1. Nā huahana Chocolate, nā pastries, nā kuki.
2. Nāʻaina hou.
3. Nā meaʻai iʻaʻa.
4. Mālama, puaa i nā ʻoli a me nā pickles.
5. ʻO ka mea momona a me ka iʻa.
6. ʻO nā huahana momona.
7. Nā meaʻai ʻona.
8. Nā kuʻuna.
9. ʻO nā mau momona.
10. Nui ka nui o nāʻano.
11. Kālā ikaika a me ke kofe.
12. Nā Loʻi.
13. ʻO ka ʻōpala a me nā kamato.

Me ka exacerbation o ka pancreatitis maʻamau, pono ia e hoʻomau i nā hoʻomaha hoʻomaha o kahi moe.

ʻO ka lāʻau lapaʻau no ka pancreas e pili ana i ka hoʻohana ʻana o:

• hoʻoweliweli enzyme e hōʻemi i ka hoʻōla o ka protere pancreatic (proteinases);
• nā mea hoʻonāukiuki e pale aku i nā kaʻina maʻi o ka ʻōpū o ka ʻōpū, ka hoʻomaʻemaʻe ʻana o ka ʻōpū omental bursa, ka hoʻomohala ʻana o ka necrosis pancreatic a me ka ʻololi cellulitis cellulose o ka wahi ma hope o ka peritoneum;
• H2 blockers e hōʻemi i ka hana o ka waikila hydrochloric;
• nā aniani e hoʻoliʻalohi i ka hoʻōla hydrochloric ma loko o ka ʻāpana;
• antispasmodics no ka hōʻoia ʻana o nā uaua palupalu e pili pū ana i ka hana sphincter impaired i ka papa pancreatic;
• nā lāʻau anticholinergic e pale ai i nā kaʻina maʻamau i loko o ka ganglia a me ka cortex cerebral;

Hoʻopili, e hoʻohana ʻia nā mea hoʻomehana enzymatic i ka hoʻomaikaʻi ʻana i ke kaʻina hana a kāpae i ka maʻi dyspeptic.

ʻO nā lāʻau kūpono

I ka lā mua o ka hoʻonāukiuki o ka ʻano maʻamau, ʻo ka hoʻohana ʻana i nā inhibitor protease no ka mālama ʻana o ka pancreatitis. Ke hoʻopau nei kēia mau lāʻau i ke kumu o ka puka ʻana o ka foci me ka hoʻolaha o nā pūnaewele necrotic.

Loaʻa nā lāʻau lapaʻau mai ka parenchyma pulmonary a me nā pancreas pipi.

Ma lalo aʻe nā mea e hoʻohana pono ai ka lāʻau lapaʻau, ʻo ka nui o nā maʻi i hoʻoholo ʻia e kekahi e ke kauka e hele ana. ʻAʻole lākou i loaʻa i ke ʻano o nā papa, akā ma ke ʻano o ka noʻonoʻo a me ka lyophilisate no ka hoʻopuʻe ʻana.

Hoʻomaopopo ʻia ka mālama ʻana o ka pancreatitis me nā mea paʻa me ka hoʻokele intravenous ma kahi kūlana wale nō. Eia kekahi, pono e mālama pono ke kahu a me ke kauka i ke ʻano o ka mea maʻi. Pono pono ʻia he Diet No. 5, ʻo ia, i ka hui pū ʻana me ka lāʻau lapaʻau, e hōʻoia i ka kūleʻa o ka mea maʻi me ke hoʻopiʻi ʻole ʻia.

Pehea e mālama ai i ka pancreatitis e wehewehe ʻia e nā poʻe loea i ke wikiō ma kēia ʻatikala.