ʻO kekahi o ke kumu o ka maʻi maʻi i ka maʻi maʻi viral. ʻAʻole i aʻo pono ʻia kēia ʻano etiological, akā ke ʻano o ke kāohi o nā hihia hou o ka maʻi type o ka maʻi type 1 ma hope o nā maʻi o nā maʻi viral e ʻike ʻia e ka hapa nui o nā poʻe endocrinologists.
ʻO ka paʻakikī o ka hoʻoholo pololei ʻana i ka pilina kumu-hiki ke paʻakikī i ka pane ʻana i ka nīnau: aʻae ʻo virus mellitus virus, he aha ia e hiki ai i nā microorganism i mea e hoʻonā ai i nā pūnaʻi pancreatic.
ʻOiai ʻo ka hōʻike ʻana o ka maʻi mellitus type 1 i ka manawa o ka maʻi o ka maʻi, i ka wā e pau nā poʻe āpau e hōʻino ai i ka insulin, e mau ʻia ka lōʻihi o nā manawa a mai nā hebedoma a hiki i ka makahiki. I ka nui o nā manawa, he paʻakikī ke hoʻokumu i kahi mea e hōʻino ʻole ai.
ʻO ke kuleana o nā maʻi i ka maʻi diabetes
No ka diabetes-hilinaʻi-makemake, a ʻano hiʻohiʻona ka wā o ka ʻike maka. ʻO ka hapa nui o nā hihia hou ua hoʻopaʻa ʻia i ka hāʻule a me ka hoʻoilo, hoʻoili pinepine ʻia ka maʻi diabetes i nā lā ʻokakopa a me Ianuali, a ʻo ka mālama liʻiliʻi loa e nānā ʻia i nā mahina o ke kauwela. He ʻano like me ka like ʻole o ka nalu ʻano like ʻole o nā maʻi like ʻole.
Ma kēia hihia, pili ka maʻi i nā kānaka āpau, akā ʻo ka poʻe wale nō he predisposition genetic ke maʻi i ka maʻi ma hope o nā maʻi maʻi maʻi.
No laila, i mea e hōʻike pono ai i ka maʻi diabetes, pono pono e hoʻololi i ke ʻano o nā chromosome a me ka mana o kahi mea hōʻino. Hoʻopili i nā maʻi, hiki i ke kumu o ke diabetes type 1 ke mau lāʻau lapaʻau, nā mea kanu, nā mea kanu meaʻai (ka waiū waiū o nā pipi, nā nitro pūpū o nā huahana ulaula).
ʻO nā maʻi e pili paha i ka hoʻomaka ʻana o nā maʻi maʻi i ka:
- ʻOkiō ka huila o ka rubella.
- ʻO ka maʻi ʻo Encephalomyocarditis.
- Reovirus ʻano 3.
- ʻŌpō.
- Koksaki V.
- Cytomegalovirus.
- ʻO ka maʻi Hepatitis C
Ua manaʻo ʻia aia i loko o hoʻokahi makahiki ma hope o ka nui o ka huhū, nui ka nui o nā maʻi o ka maʻi o ka maʻi i nā keiki, ke loaʻa nei kekahi mau mea maʻi i ka metabolism hōʻeha a hiki i ka hyperglycemia a me ke ketoacidosis i ka manawa o ka maʻi.
ʻO ke ʻano o ka adenoviruses a me ka maʻi influenza i ka hoʻomohala ʻana o ka hana ʻino i nā cell beta i kēlā me kēia me ka predisposition i loaʻa i ka maʻi diabetes.
No laila, no nā mea maʻi i ka pilikia, pono ke pale aku i nā maluhia o nā pō i ke manawa e pono ai.
ʻO ka hoʻokūkū o nā hopena hōʻino o nā maʻi i ka maʻi diabetes
Inā komo ka maʻi i loko o ke kino, hiki iā ia ke loaʻa ka hopena make hewa i nā cell beta, e hoʻokau ana i ko lākou make. ʻO ka mea ʻelua e alakaʻi i ka luku ʻana i ka islet islet is the development of indirect immune response. I ka manawa like, e loli ka waiwai o nā membranes ma hope o lākou e ʻike ʻia e ke kino e like me nā antigens a nā haole.
I ka paneʻana i nā hiʻohiʻona o kēlā mau antigens, hoʻomaka ka hana ʻana o nā antibodies i ka membrane, e alakaʻi ana i kahi kaʻina maʻi a hahai ʻia e ka luku kino ʻana. Ke loli nei ka hana o ka ʻōnaehana pale piha ʻana, ka nāwaliwali o ka pale mai nāwaliwali, a e hoʻonui ʻia nā ʻano pono i nā pūnaʻi ponoʻī.
Ke hōʻike ikaika nei ka hana i nā mea maʻi me ka luku koke ʻana i nā pū i nā mea make - nitrates, nā lāʻau lapaʻau, nā mea hoʻonaninani, nā pehu, inā loaʻa ka maʻi ʻeha.
ʻO ka luku ʻia ʻana o nā cell pancreatic a me nā hōʻike like me nā maʻi ākea e pili ana i ka maʻi diabetes i nā manawa he nui:
- Kūlana preclinical: ʻaʻohe ʻike o ka maʻi maʻi, ka hoʻokaʻa o ke koko, ke ʻano o ka antibodies i nā peka beta pancreatic i loko o ke koko.
- ʻO ke ʻano o ka maʻi maʻamau: ʻo ka wikiwiki ka puasa glycemia, ke hōʻike nei ka hoʻohaʻahaʻa glucose i ka hoʻemi ʻana i ka mea huna o ka insulin, no ka mea he ʻelua hola ma hope o ka hoʻokomo ʻana o ka glucose i kona pae koko ma mua o ka maʻamau.
- Hoʻololi i ka maʻi mellitus maʻi maʻamau: aia kekahi mau hōʻailona mua o ka nui o ka nui o ke kō (koko, nui ka makemake, nui loa ka hopena i ka urine, glucosuria). Ua luku ʻia ma mua o 90% o nā ʻōleka beta.
Antibodies i nā cell antigens a me nā cytoplasm e ʻike ʻia i loko o nā malama mua o ka maʻi, a laila, ma ka hoʻomau ʻana o ka maʻi diabetes, e emi ana ko lākou helu.
ʻO kā lākou ʻike i ke koko ke hōʻike nei i ka hiki ke hoʻomohala ʻana i ka maʻi diabetes type 1.
Kāpae Kīwī maʻamau 1
I ke kahakaha iho, ʻo ke koho kūpono loa e hoʻopau i nā mea ʻino no ka poʻe i loaʻa i kahi predisposition hoʻoilina i ka maʻi maʻi maʻi. Ma ka hoʻomaʻamaʻa, pilikia loa kēia pilikia, ʻoiai nā mea maʻi, nā nitrates a me nā mea huakini e pili pono ana.
Hāʻawi ʻia i ka hana o nā maʻi i ka hoʻomohala ʻana i ke ʻano maʻi type 1, ka huakaʻi kūʻē ʻana i ka huehue aheaʻi, ʻōpala, Koksaki a me rubella. Akā i kēia manawa ʻaʻole i loaʻa ka laha ākea, no ka mea hiki ke hoʻomohala i kahi pane autoimmune i nā maʻi.
ʻO kahi ala paʻa i ka pale ʻana i ka maʻi hānai ma ke keiki e ʻōpiopio nei, me ka waiū o ka makuahine ka piha o nā immunoglobulins pale, a me ka waiū waiū o nā bipi i nā keiki predisposed genetically hoʻonui i ka hiki ke hoʻomohala ʻana i ka maʻi mellitus, e hōʻike ana iā ia iho i ka hoʻokūkū o ke kūlohelohe o ke kuʻuna, ka hoʻonui ʻana i ka ʻāpana o nā antibodies i nā cell beta a me ka insulin.
ʻO nā ʻano aʻoaʻo no ka pale ʻana i ka maʻi maʻi me nā ʻano e hiki ke hōʻole i ka hoʻomaka ʻana o ka hōʻike, ʻo ia hoʻi, ka maʻi kūlohelohe, a e hōʻemi paha i ka nui o kāna mau hōʻike maʻi. He nui nā ʻano aʻoaʻo i kēia:
- Ka hoʻohana ʻana o kahi immunosuppressor - Cyclosporin A. Ke hoʻomoe nei i ka make o nā cell beta. Hiki i ke kala ʻana i ka maʻi diabetes no hoʻokahi makahiki.
- Mālama ka Vitamin D i ka hoʻolālāʻana o ka luku autoimmune o ka pancreas. Loaʻa nā hopena maikaʻi i ka hoʻonoho ʻana i ka wā kamaliʻi.
- Nā Nicotianamide. ʻO ka loina Nicotinic i ke kōneʻi type 2 e hoʻolōʻihi i ka manawa o ke kala. Hiki i ka lāʻau ke hoʻohaʻahaʻa i ka pono o ka insulin.
- ʻO ka immunomodulator Linamide ma nā haʻahaʻa haʻahaʻa e pale i nā pū o nā beta i ka wā i hāʻawi ʻia i ke kūlana preclinical.
Hiki i ka paleʻana i ka insulin ke hoʻolōʻihi i ka hoʻomaka ʻana o ka maʻi diabetes i nā hoahānau aloha mua. ʻAʻohe manaʻo hōʻike inā hiki i ka hoʻokaʻawale ʻana o nā insulin e hiki ke hoʻolohi i ka hoʻomohala ʻana i ka maʻi diabetes i nā makahiki 2-3. ʻAʻole lawa kēia mau hōʻike hōʻike kumu.
Pēlā pū kekahi hoʻokolohua pū me ka hoʻomaʻamaʻa ʻana me nā lymphocytes palupalu, kahi i komo ai i ka autoimmune reaksi. Ke hana ʻia nei nā haʻawina o ka hoʻokele prophylactic o ka insulin i ka wā e lawelawe ai i ka waha a i ʻole ka intranasally ma ke ʻano o ka aerosol.
I mea e hōʻemi ai i ka hopena o ka hoʻomohala ʻana i ka maʻi maʻamau i nā keiki, koi ʻia ka prophylaxis maʻi i ka wā e hoʻolālā ana i ka wā hāpai, a i ka wā e kūkulu ʻia ai ka hānau ʻana. No laila, me ka predisposition heruli, he nānā ʻana i nā mākua ma mua a me nā nānā ʻana o ka wahine i ka wā o ka hānau ʻana.
ʻO kekahi loea mai ka wikiō ma kēia ʻatikala e kamaʻilio e pili ana i nā ala e pale ai i ka maʻi diabetes.
