Hoʻohana ʻia ka mālama ʻana i ka maʻi diabetes me ka hoʻohana ʻana i nā lāʻau lapaʻau, inā ʻole ka hana ʻana o ko lākou iho pono iho (insulin), hiki ke hoʻohaʻahaʻa i ka glycemia kiʻekiʻe a pale i nā hōʻeha o ka maʻi.
Hiki ke hoʻokaʻawale ʻia nā lāʻau āpau i ʻelua mau pūʻulu: insulins o nā ʻano like ʻole o ka hana a me nā lāʻau papa tableted. Ma ke ʻano mua o ke ʻano maʻi maʻi, pono i nā mea maʻi ke insulin, ka mālama ʻana o nā mea maʻi me ka maʻi diabetes type 2 e pili ana i kona hoʻopili ʻana i ka hui pū ʻana i mua o nā hōʻailona kūʻokoʻa.
Ke mālama nei i ka hoʻōla insulin me ka hōʻola i ka kūlohelohe kūlohelohe o ka hana a hoʻokuʻu i ka hormone mai nā pulela islet o ka pancreas, no laila, nā lāʻau lapaʻau me kahi hana pōkole, lōʻihi a lōʻihi e pono ai.
Pehea e hana ai ka insulin me ka protamine?
Hoʻohui ʻia kahi mea kūikawā i kapa ʻia ka protamine i nā insulins medium-hana e hoʻolohi i ka hoʻopoʻi ʻana o ka lāʻau mai ka pūnaewele injection. Mahalo i ka protamine, ʻo ka hoʻomaka ʻana o ka emi ʻana o ke kō koko koko hoʻomaka i ʻelua a ʻehā mau hola ma hope o ka hoʻokele ʻana.
Loaʻa ka hopena kiʻekiʻe ma hope o nā hola 4-9, a ʻo ka lōʻihi holoʻokoʻa mai 10 a 16 mau hola. ʻO kēlā mau hiʻohiʻona o ka helu o ka hoʻomaka ʻana o ka hopena hypoglycemic e hiki ai i nā insulins ke hoʻololi i ka hana o ka pilikino pilikino.
ʻO ka Protamine ke kumu o ka hoʻomohala ʻana i nā ʻenemi insulin i ke ʻano o nā mea o nā flakes, no laila ke ao nei ke ʻano o ka protamine insulin, a ua palaka nā mākaukau o nā insulins pōkole. Kūkulu ʻia ka ʻano o ka lāʻau i ka zinc chloride, sodium phosphate, fenol (preservative) a me ka glycerin. Hoʻokahi milliliter o ka hana hoʻōki i ka protamine-zinc-insulin e loaʻa i kahi 40 PIECES o ka hormone.
ʻO ka hoʻomākaukau ʻana no ka insulin protamine i hana ʻia e RUE Belmedpreparaty ka inoa pāʻoihana ʻo Protamine-Insulin ChS. ʻO ka ʻano hana o kēia lāʻau lapaʻau e wehewehe ʻia e nā hopena like ʻole:
- Hoʻopili ʻia me ka ʻili o ka membrane kelepona.
- ʻO ka hoʻokumuʻana o kahi paʻakikī receptor complex.
- I loko o nā pūlima o nā ate, nā ʻili a me nā kiko adipose, hoʻomaka ʻia ke ʻano o ka hoʻouka ʻana o nā enzyme.
- Hoʻopili ʻia nā kolo a hoʻopili ʻia e nā ʻili.
- Hoʻokokoke ʻia ka halihali o Intracellular.
- Hoʻokumu ʻia ka hoʻohālikelike ʻana o nā momona, protein a me glycogen.
- Ma nā puʻu, e emi ana ka weheʻana o nā molekena glucose hou.
Ke hoʻohālikelike nei kēia kaʻina hana āpau i ka hoʻohaʻahaʻa i ka pae o ka glucose i ke koko a me ka hoʻohana ʻana iā ia e hana i ka ikehu i loko o ka pūnaehana. ʻO ka uku o ka hoʻomaka ʻana a me ka lōʻihi o ka hana o ka Protamine insulin ES ma ka mea i hoʻopaʻa ʻia, ʻĀina a me nā wahi o ka injection.
I ka mea like, ʻokoʻa paha kēia mau ʻōhua i nā lā ʻokoʻa.
Nā hōʻike no ka hoʻohana a me ka helu ʻana o ka lāʻau lapaʻau
Hōʻike ʻia ka hoʻomākaukau ʻana ʻo Protamine-zinc-insulin no nā mea maʻi me ka maʻi diabetes mellitus mua loa, a hiki ke hōʻike ʻia no ka glucose koko kiʻekiʻe ma ke ʻano o ka maʻi ʻelua.
Hiki i kēia ke pale i nā papa i hōʻemi i ke kō koko koko, me ka hoʻohui o nā maʻi hopohopo a me nā mea ʻē aʻe e like ai me ka wā hāpai. ʻO nā mea maʻi me ka maʻi diabetes mellitus type 2 e hoʻoneʻe ʻia i ka therapy insulin inā i hui pū ʻia ka maʻi maʻi me nā maʻi ʻehaʻehā.
Hōʻike ʻia nā lāʻau like ʻole e like me ka protamine-zinc-insulin inā pono ke hana inā loaʻa mua ke maʻi maʻi a nānā mua ʻia nā helu glycemic a i ʻole he contraindications i nā papa.
Hoʻokomo ka protocol-insulin i ka subcutaneously, ʻo kona ʻano ʻona i hilinaʻi i kēlā me kēia hōʻailona indahi hyperglycemia a ua helu ʻia ʻo ia ma kēlā me kēia 1 kg o ke kaumaha o ke kino. Hoʻolaha ka hana i kēlā me kēia lā i ka 0.5 a 1 hui.
Nā hiʻohiʻona o ka lāʻau lapaʻau:
- Hoʻohana wale ʻia ʻo ia wale nō subcutaneously. Hoʻowahāwahā ʻia ʻo ka hoʻokele ʻia ʻana o ka insulin.
- Mālama ʻia ka hūpī paʻa ʻia i loko o ka friji, a i ka wa i hoʻohana ai i ka mahana a hiki i ka 25 degere a hiki i 6 wiki.
- E mālama i ke kīwī i hoʻohana ʻia o ka insulin i ka mahana o ka lumi (a hiki i 25 ° C) no 6 mau pule.
- ʻO ka mahana o ka insulin me ka hoʻopuka e pono ke ʻano o ka lumi lumi.
- Ma lalo o ka hopena o ka wela, kūlohelohe i ka lā, ka manuahi, ua pau ka insulin i kona waiwai.
- Ma mua o ka lawelawe ʻana i ka protamine, pono e ʻili ʻia ka insulin zinc i loko o nā kuʻekuʻe a hiki i kona ʻano a me ke ao. Inā hiki ʻole kēia e hana, a laila ʻaʻole lawelawe ʻia ka lāʻau.
Hiki ke koho ʻia ka paena i ka maʻi maʻi e pili ana i ka makemake o ka mea maʻi, akā pono e hoʻomau ʻia i loko o ka noʻonoʻo a komo ʻia ka lewa a me ka lohi o ka ʻūhā. ʻO ka lua ʻona e ʻōlelo ʻia ai, ʻo ia ka ʻūhā poʻohiwi (deltoid muscle). I kēlā me kēia manawa kou pono e koho i kahi wahi hou ma loko o ke ʻano anatomical like i mea e pale ai i ka luku ʻana i ke kiko subcutaneous.
Inā hoʻoholo ʻia ka mea maʻi i ka ulu ʻana i ka insulin, a laila mālama ʻia ka protamine zinc i ke kakahiaka a i ke ahiahi paha, a hōʻike ʻia, ʻelua (kakahiaka a me ke ahiahi). Ma mua o ka ʻai ʻana, e hoʻohana ʻia kahi ʻano pōkole o ka insulin.
Ma ka lua o nā maʻi maʻi maʻi, ʻae pinepine ʻia ka Protamine-insulin ES e hui pū me nā lāʻau glypoglycemic, i kuhikuhi ʻia no ka lawelawe waha, i mea e hoʻomaikaʻi ai i ko lākou hopena.
ʻO nā hoʻohālikelike o ka Insulin Treatment
ʻO ka mea pinepine ka hoʻopiʻi pinepine ʻana i ka hauola insulin o ka emi ʻana o ke koena o ka glucose o lalo o ka pae ma lalo o nā pae maʻamau. Hoʻolomo ʻia kēia i ka maʻi palaka me ka liʻiliʻi haʻahaʻa me ka wai kiʻekiʻe o ka insulin, ke ʻoki ʻana i ka ʻai, ke kaumaha kino, hoʻololi i ka pūnaewele hōʻona.
Hoʻopilikia ʻia ka hypoglycemia e nā maʻi concomitant, ʻoi aku ka poʻe me ka maʻi kiʻekiʻe, ke nānā ʻana, ka luaʻi ʻana, a me ka hoʻohui ʻana o nā lāʻau e hoʻoikaika ai i ka hana o ka insulin.
ʻO ka hoʻomaka koke ʻana o nā hōʻailona o ka hypoglycemia maʻamau no ka mālama ʻana i ka insulin. ʻO ka hapa pinepine, nā mea maʻi e manaʻo i kahi hopohopo, nā kaumaha, ke anu anuanu, nā lima haʻalulu, nāwaliwali maʻamau, nā hōʻeha a me nā palpitations.
Hōʻalo ka ʻili, piʻi ka pōloli i ka manawa like e like me ka maʻi neʻe. A laila huhū kahi ʻike a hāʻule ka mea maʻi i kahi coma. Hoʻopilikia ka hopena i ke kōʻai koko i mea palupalu i ka lolo a inā ʻaʻole i hoʻomaʻamaʻa ʻia, ʻike nui ka poʻe maʻi i ka make.
Inā ʻike ka mea maʻi me ka maʻi maʻi maʻi, a laila hiki iā ʻoe ke hōʻoluʻolu i ka mea e hoʻohana ana i ke kō a me ka wai momona, nā kuki. Me kahi kiʻekiʻe kiʻekiʻe o ka hypoglycemia, ke kūpaʻa nei ka hopena o ka glucose a me ka glagon intramuscular intravenously. Ma hope o ka hoʻomaikaʻi maikaʻi ʻana i ka pōmaikaʻi, pono nui ka mea maʻi e ʻai ʻana no ka mea ʻole ka hoʻopaʻi hou ʻana.
Hiki i kahi koho dosis kūpono ʻole a i ʻole hoʻokele hoʻomalu ke hana i kahi hōʻeha o ka hyperglycemia i nā maʻi maʻi insulin. Hoʻonui pinepine ʻia kāna mau hōʻailona, ʻo ka hiʻohiʻona maʻamau o ko lākou helehelena i loko o kekahi mau hola, i kekahi manawa a hala ʻelua mau lā. Hoʻonui ka wai, hoʻonui ka wai i ka urine, hoʻoemi ka momona.
A laila aia he nausea, luaʻi, ka honi o ka acetone mai ka waha. I ka hala ʻole o nā insulin, e hāʻule ana ka mea maʻi i ka coma maʻi. Pono ka mālama kuhi no ka coma coma a kahi hui ambulance e koi ʻia.
No ka koho pono o ka ʻona, pono e noʻonoʻo i ka manawa e loli ai ke ʻano o ka mea maʻi a i ʻole nā mea e hui ai nā maʻi, pono ke hoʻoponopono ʻia. Hōʻike ʻia i ia mau hihia:
- Nā maʻi hōʻeha o ka gland thyroid.
- ʻO nā maʻi o ka ate a me nā ʻōpū paha, keu i ka wā kahiko.
- Nā maʻi maʻi maʻi.
- ʻO ka hana pilikino.
- Ke hoʻololi ʻana i kekahi meaʻai.
- ʻO ka hoʻololi o nā ʻano o ka insulin, ka hana, hoʻololi mai ka holoholona a i ke kanaka.
ʻO ka hoʻohanaʻana o ka inulin a me nā lāʻau lapaʻau mai ka hui o thiazolidinediones (Aktos, Avandia) e hoʻonui i ka hōʻeha o ka puʻuwai puʻuwai. No laila, ua hāʻawi ʻia nā mea maʻi me ka puʻuwai naʻau hemahema e nānā i ka paona kino i mea e ʻike ai i ka edema latent.
Hiki i nā ʻōmaʻomaʻo ke pili i ka wahi ma ke ʻano o ka puhi, ʻulaʻula, a i ʻole ka ʻeha ʻili. ʻO ka maʻa mau ke manawa pōkole lākou a kau ma ke kaʻa. ʻO nā hōʻike maʻamau o nā alaka e hiki ai i kēlā mau hōʻailona: kahi hāmaki ma ke kino, nausea, angioedema, tachycardia, pōkole o ka hanu. I ka wā e loaʻa ai, hana ʻia ka lāʻau lapaʻau kūikawā.
Hoʻopilikia ka Protamine-insulin i ka hihia o kēlā me kēia hypersensitivity a me hypoglycemia.
Insulin Protamine i ka wā hāpai a me ka lactation
No ka mea ʻaʻole i hala ka insulin i ka plasenta, i ka wā hāpai a hiki ke hoʻohana ʻia e uku no ka maʻi diabetes. Ke hoʻolālā nei i ka wā hāpai, ua hōʻike ʻia kahi hōʻike ʻana o ka wahine me ka maʻi maʻi maʻi maʻi.
Hoʻomaka ka trimester mua e pili ana i ke kua o ka hoʻemi ʻana i ka pono o ka insulin, a me ka lua a me ke kolu me ka hoʻonui nui ʻana i ka lāʻau kūleʻa. ma hope o ka hānau keiki ʻana, lawe ʻia ka hana insulin ma nā ʻano maʻamau. I ka manawa hoʻokae, hiki ke loaʻa kahi hōʻemi nui i ka hopena o ka lāʻau lapaʻau i mālama ʻia.
Hiki ke hoʻohui ʻia ka lactation a me ke keʻena o ka insulin, no ka mea, ʻaʻole hiki i ka insulin ke komo i ka waiū umauma. Akā ʻo nā loli i ka hope o ka hormonal o ka wahine e koi pinepine i ka nui ʻana o ka pae o ka glycemia a me ke koho ʻana i nā kūpono kūpono.
ʻO ke kikowaena o ka insulin me nā lāʻau lapaʻau ʻē aʻe
Hoʻonui ʻia ka hana o ka insulin i ka wā i hoʻohana pū ʻia ai me nā papa kōnohi, nā beta-blockers, sulfonamides, tetracycline, ka hoʻomākaukau ʻana o lithium, ka bitamina B6.
Bromocriptine, nā anabolic steroid. Hiki i nā hypoglycemia me ka hui pū me ka insulin a me ka katingenazole, clofibrate, mebendazole, cyclophosphamide, a me ka waiʻona etil.
Makemake nui nā mea maʻi i ka nīnau pehea e hōʻemi ai i ka insulin i ke koko. Nikotine, morphine, clonidine, danazole, tablet contraceptives, heparin, thiazide diuretics, glucocorticosteroids, tricyclic antidepressants, thyroid hormone, sympathomimetics a calcium antagonists hiki ke hōʻemi i ka hana insulin.
E haʻi ke wikiō ma kēia ʻatikala i ka manawa e pono ai ka insulin a pehea e hoʻokomo ai.
