Ma ka maʻi mellitus o ka lua o ke ʻano, ke kauka, ma ke ʻano he kānāwai, e kuhikuhi ana ʻaʻole wale nō ka mālama ʻana i ka mālama ʻana i ka lāʻau, ʻohi kino kūlohelohe, akā pū kekahi pū me nā hypoglycemic kūikawā i nā papa o nā papa, e ʻae ana e mālama i ke kiʻekiʻe o ka glucose i loko o ke koko. Ua koho ʻia nā lāʻau lapaʻau e pili ana i ke kūlana maʻamau o ke kino o ka mea maʻi, ka glucose i ke koko a me ka urine, nā ʻano o ka maʻi a me ka hele ʻana o nā maʻi liʻiliʻi.
I kēia lā i loko o nā hale kūʻai ʻike hiki ke loaʻa i kahi papa inoa nui o nā lālani hanauna hou i lawe ʻia no ka maʻi diabetes type 2. Eia nō naʻe, pono e koho i nā lāʻau lapaʻau haʻahaʻa ma hope o ka nīnau ʻana i ke kauka, no ka mea, ʻaʻole pono e noʻonoʻo pono i nā ʻano āpau o nā maʻi, contraindications, akā, ʻo ka ʻano pono hoʻi. Ma muli o ka hoʻohana ʻole ʻana me ka ʻōlelo lapaʻau e hiki ke hōʻeha i kou olakino.
He mea nui ia e noʻonoʻo pono ʻaʻole hoʻohana ʻia nā lāʻau lapaʻau i ka mālama ʻana i ka maʻi maʻi type 1 i nā keiki a ua koho kūikawā ʻia no ka maʻi maʻi ma nā wahine hāpai.
Hoʻokaʻawale ʻia nā koina loi o ka wai o ka wā kahiko a me ka wā hou i nā ʻano ʻekolu, ʻokoʻa lākou i ka ʻaila kemika a ma ke ʻano e pili ai i ke kino.
Hoʻohana ʻia ka Sulfonamide
- E like me nā ʻaihue hypoglycemic like i ka maʻi diabetes e kōkua hou i ka hoʻoulu hou ʻana a hāʻawi i ka insulin i ka koko.
- Hoʻonui pū kekahi lāʻau lapaʻau i ka hoʻonaninani ʻana i nā ʻili o nā kino, e hiki ai iā ʻoe ke kiʻi i ka nui e pono ai o ka insulin.
- Hoʻonui ʻo Sulfanilamides i ka nui o nā mea i nānā i ka insulin i nā mea puna.
- Ke kōkua nei ka hoʻoliʻi ʻana i ka Sugar a hōʻemi i ka hoʻokumu ʻana o ka glucose i ka ate.
No ka manawa lōʻihi, ua hoʻohana ka maʻi maʻi ma mua o nā lāʻau lapaʻau mua. I mea e hana ai i ka pono o kēlā me kēia lā no ka lāʻau lapaʻau, pono e lawe nā mea maʻi mai ka 0.5 a 2 mau grika o ka sulfonamides, he ʻano haʻahaʻa nui loa. I kēia mau lā, ua hoʻokumu ʻia nā lāʻau lapaʻau lua aku i mea e ʻoi aku ka maikaʻi.
ʻOi aku ka liʻiliʻi o kā lākou dosage, ka mea e liʻiliʻi ai ka liʻiliʻi.
Ma ke kānāwai, he hopena nā lāʻau lapaʻau i ke kino no nā hola 6-12. Lawe ʻia lākou i ka papa ʻaina 0,5 ma mua a i ʻole maʻa o ka papa ʻaina ʻelua i ka lā.
I kekahi mau manawa, ke kauka nei ke kauka i ka lāʻau i ʻekolu mau manawa i ka lā e hiki ai ke hōʻemi iki i ka kaila koko.
Ma ka hoʻohaʻahaʻa i ke kō koko koko, loaʻa kēia mau lāʻau maikaʻi i nā kīʻaha koko, hoʻomaikaʻi i ko lākou kahe koko a pale i ka hōʻeha ʻana i nā moku liʻiliʻi. Ke komo pū nei i nā papa e hoʻemi i ka kōkē lua no nā lua ʻelua, ke hoʻopau koke nei lākou i ke kino a ʻaʻole i ka hoʻolalelima ʻana i nā lolo, pale i nā ʻāpana o ke kino mai ka hoʻomohala ʻana i nā ʻōmole ma muli o ke ʻano maʻi type 2.
I kēia wā, ʻo nā lāʻau hōʻemi haʻahaʻa e like me sulfonamides aia i kā lākou drawbacks:
- ʻAʻole kūpono kēia lāʻau lapaʻau i nā maʻi āpau.
- Ke hoʻāʻo nei lākou e kahakaha ʻana i nā poʻe ʻelemakule e hoʻohemo mālie nei i nā lāʻau mai ke kino. Inā ʻaʻole, hiki i ka lāʻau ke hōʻiliʻili i ke kino, ke alakaʻi pinepine nei i kahi kūlana hypoglycemic a me ka coma.
- Hiki i ke Sulfanilamides ke hoʻohui i hope ma hope o kekahi manawa ma muli o ka elima mau makahiki ma hope o ka hoʻohana ʻana i ka lāʻau, hōʻemi ka manaʻo o nā receptors kiko i ko lākou mau hopena. ʻO ka hopena, nalowale nā mea hoʻoponopono.
Ke komo pū nei i nā hiʻohiʻona maikaʻi ʻole o ka lāʻau ʻo ka ʻoiaʻiʻo o ka sulfonamides koi i hōʻemi i ka pae o ka glucose i loko o ke koko, e hiki ai i ka hopena hypoglycemic. ʻO ka maʻi koʻikoʻi o ka hypoglycemia e hoʻoulu ʻia e nā lāʻau lapaʻau o nā pūʻulu chlorpropamide a me nā glibenclamide. No kēia kumu, pono e nānā pono ʻia ka lāʻau i kauoha ʻia e ke kauka a ʻaʻole lapaʻau ʻia pono.
He mea nui e hoʻomanaʻo e pili pinepine ana i ka ʻaina inu, ka hoʻohana ʻana i nā mea inu wai, ikaika kino kino, a me ka aspirin hiki i ka glycemia. No laila, ma mua o ka hoʻomaka ʻana i ka hoʻohana ʻana i ka lāʻau lapaʻau, pono ʻoe e nīnau i kāu kauka e pili ana i ka hele ʻana o nā contraindications.
ʻO wai e hōʻike ʻia no ka lawe ʻana i nā lāʻau sulfa?
ʻO nā laikini hoʻohaʻahaʻa hilahila o kēia ʻano i ʻōlelo ʻia i loko o kēia mau hihia.
- Ma ka mālama ʻana i ka maʻi mellitus o ka maʻi mua, inā ʻaʻole ʻae ʻia ka mālama ʻana i ka pae o ka glucose i loko o ke koko, ʻaʻole nui ka mea maʻi.
- Me ka mellitus o ka maʻi mellitus o ke ʻano mua, inā he maʻi nui ka mea maʻi.
- Me ka mellitus maʻamau diabetes mellitus o ke ʻano mua.
- Inā ʻaʻole manaʻo ka mea maʻi i ka hopena o ka hōʻemiʻana i ka insulin no ka maʻi type 1.
I kekahi mau hihia, ua kuhikuhi ʻia ʻo sulfonamides me ka hoʻohui pū me ka insulin. Pono kēia e hoʻomaikaʻi i ka hopena o ka insulin i ke kino a unuhi i ka maʻi maʻamau i loko o kahi ʻano paʻa.
Hiki i ka hanauna sulfanilamides mua ke lawe ʻia ma mua, i ka wā a ma hope o ka ʻaina. I kēia hihia, ua kuhikuhi ʻia ke ʻano o ka mea hoʻonaninani. Ma mua o ka hoʻomaka ʻana i ka lawe ʻana i ka lāʻau lapaʻau, pono ʻoe e noʻonoʻo pono i nā ʻōkuhi.
Lawe lākou i nā lāʻau hoʻohiolo haʻahaʻa o kēia ʻano me ka mālama nui loa i ka mālama ʻana i ke ʻano nui, ʻo ka lawe ʻana i ka hala hewa o ka lāʻau hiki ke piʻi i ka kahe ʻana o ke kōʻai, ke ʻano kuʻuna, maʻi, ka luaʻi, ka ʻōpū o ka ʻōpū a me ka ʻāʻī, a me ka hoʻēmi ʻana i ka nui o nā kō ke koko keʻokeʻo a me ka hemoglobin.
Hoʻomalu Biguanide
ʻO nā lāʻau lapaʻau like haʻahaʻa like me ka hopena ʻē aʻe i ke kino, ma muli o ke kō e hiki ke komo koke ʻia ai ka hilo e nā ʻōpala kiko. Hoʻohālikelike ʻia nā mea ʻike nui i ka biguanides i kahi hopena i nā mea kūleʻa o ka cell, e hoʻomaikaʻi i ka hana o ka insulin a kōkua i ke ʻano o ke kō koko.
He nui nā pono o kēia mau lāʻau haʻahaʻa kālā.
- Hoʻemi i ka glucose koko.
- Hoʻemi i ka komoʻana o ka glucose i loko o ka pākaukau a me kona hoʻokuʻu i ka ate.
- ʻAʻole hiki i nā lāʻau lapaʻau ke hana i ka glucose i loko o ke akea.
- Hoʻonui ka lāʻau i ka nui o nā mea taliaina e nānā i ka insulin.
- Ke kōkua nei nā lāʻau lapaʻau e wāwahi a puhi i ka momona o ka kino i makemake ʻole ʻia.
- Ma lalo o ka hopena o ka lāʻau, nā wai koko.
- Hoʻemi ka momona o ka mea maʻi, hiki iā ʻoe ke lilo i ka momona.
ʻAʻole pā ka Biguanides i ka hana o ka insulin, kōkua i ka hoʻohana ʻana o ka glucose i nā kiko, hoʻonui i ka hopena o ka insulin i hoʻokomo ʻia a i ʻole i loko o ke kino. Hōʻole kēia i ka mea i hoʻolaʻa ʻole nā cell i ko lākou mālama.
Ma muli o ke ʻano maʻamau o ka hana ʻana i ka insulin i ka mea maʻi, hoʻemi ka nui o ka momona, kahi mea pono loa ia no ka maʻi maʻi a me ka poʻe e momona a i ke kaumaha paha ke kino. Ma muli o ka emi ʻana o ke kao o ka glucose i loko o ka ʻōpū, hoʻomaʻamaʻa ka pae o nā huaʻōlelo lipid i ke koko, ka mea e pale ai i ka hoʻomohala ʻana o ka atherosclerosis.
Eia naʻe, loaʻa nā biguanides. Hāʻawi i kēia mau lāʻau i nā huahana waikawa e hōʻiliʻili i loko o ke kino, e alakaʻi ana i ka hypoxia tissue a i ka pōloli oxygen.
Pono e hoʻohana pono ʻia ka lāʻau lapaʻau me ka maʻi maʻi maʻi o ka poʻe makua a me kēlā poʻe e loaʻa nā maʻi o ka pūpū, nā lewa a me ka puʻuwai. Inā ʻaʻole, ʻike paha nā mea maʻi i ka luaʻi, nilo, nā kīwaha, hōʻeha o ka ʻōpū, a me nā maʻi.
ʻAi ʻia ka Biguanides e hoʻohana:
- ʻO nā maʻi i ʻoi aku ma mua o 60 mau makahiki;
- i ka mua o kēlā me kēia ʻano o ka hypoxia;
- e pili ana i ka puʻuwai a me nā maʻi maʻi;
- i ke alo o kēlā me kēia maʻi mākaʻi, maʻi nui a me nā maʻi.
Hoʻokomo mua ʻia ʻo Biguanides i nā maʻi me ka maʻi maʻi o ka maʻi mellitus type 2, me ke kaumaha o ke kino maʻamau a me ka hemahema o ka ketoacidosis. Eia nō hoʻi, ua hoʻohana ʻia kēia mau lāʻau lapaʻau i ka mālama ʻana i nā maʻi maʻi maʻi, ka ʻuhane o ke kino ʻaʻole i ʻae i ka sulfonamides a i ʻole ka hoʻohui i kēia lāʻau lapaʻau.
ʻO Biguanides, ka mea i loaʻa i ka mua "retard" ma ka inoa, e hoʻopili i ke kino ma mua o nā lāʻau lapaʻau maʻamau. Pono ʻoe e lawe i ka lāʻau lapaʻau ma hope wale nō o ka ʻai ʻana, kahi hana maʻalahi - ʻekolu mau manawa i ka lā, ka hana lōʻihi - ʻelua mau manawa i ka lā, kakahiaka a me ke ahiahi.
ʻO kēia ʻano lāʻau lapaʻau e komo pū i nā lāʻau like e like me ka adebit a me ka glyformin. Eia nō kekahi, ʻo kēia mau lāʻau lapaʻau e hoʻohana ʻia e nā kānaka olakino e hōʻemi i ka nui o ke kino momona.
Nā lāʻau lapaʻau e hoʻopili ai i ka lawe ʻana o ka glucose i loko o nā pā
I kēia mau lā, ʻaʻole i hoʻolaha nui nā lāʻau like i loko o Rūsia, no ka mea he uku nui lākou. Eia naʻe, aia i waho, ua kaulana loa kēia mau lāʻau i waena o nā mea maʻi ma muli o ka hana kiʻekiʻe. ʻO ka mea kaulana loa ka glucobai laola.
ʻO Glucobai a i ʻole acarbose, hiki iā ʻoe ke hoʻolohi i ke kaʻina o ke kaʻohi ʻana o ka glucose i loko o ka ʻōpū a me kona komo i loko o nā kīʻaha koko. E kōkua ana kēia i ka pae haʻahaʻa ma nā ʻano maʻi like ʻole. Eia kekahi, ʻo kēia lāʻau lapaʻau e hōʻemi i ka nui o nā triglycerides i loko o ke koko, e hoʻomohala i kahi hilinaʻi i ka insulin i nā poʻe maʻi me ka diabetes mellitus type 2, e alakaʻi pinepine ana i ka atherosclerosis.
ʻO ka pinepine, ʻo ka glucobai i kuhikuhi ʻia no ka maʻi mellitus type 2 i ke kumu ʻo ka mālama koʻikoʻi a i ʻole me ka sulfonamides. I ke ʻano type type 1, hoʻohana ʻia kēia lāʻau lapaʻau me ka hoʻopuka ʻana o ka insulin i ke kino. I kēia hihia, ua hoʻemi ʻia ka nui o ka hoʻomehana ʻana o ka insulin.
No ka mea ʻaʻole kēia lāʻau lapaʻau i ka hopena hypoglycemic, ua kuhikuhi pinepine ʻia ka glucobai no ka poʻe elemakule. Eia nō naʻe, he hopena paha ka hopena o ka lāʻau, e like me ka palaka a me ka pua ʻana.
ʻAʻole e lawe ʻia ka Glucobai e nā mea maʻi ma lalo o ka makahiki 18, me nā maʻi o ka pēpē o ka gastrointestinal, i ka wā hapai a me ka ʻōpiopio. Hoʻokomo ʻia ka lāʻau lapaʻau ʻole ʻia no ka hoʻohana ʻana i ka gastroparesis e kumu ʻana i ka neuropathy maʻi maʻi.
Lawe ʻia ka lāʻau lapaʻau i nā lā mua o 0,05 mau grika ʻekolu mau manawa i ka lā. Inā kūpono, hoʻonui pinepine ʻia ka pākana e 0.1, 0.2 a i ʻole 0.3 kākolu mau manawa ʻekolu i ka lā. ʻAʻole ʻōlelo ʻia ka nui o nā lāʻau lapaʻau. Pono e hoʻonui pinepine ʻia ka nui dosage, i kekahi manawa i hoʻokahi a ʻelua mau pule.
Lawe ʻia ka Glucobay ma mua o ka ʻai ʻole me ka ʻaina ʻole. Pono ka holoi i ka lāʻau lapaʻau me ka liʻiliʻi liʻiliʻi o ka wai. Hoʻomaka koke ka hana o ka lāʻau lapaʻau ma hope o ke komo ʻana i ka ʻōpū.
Pehea e lawe ai i nā lāʻau lapaʻau haʻahaʻa
ʻO ka lāʻau lapaʻau e like me Manilin no ka maʻi hānai, lawe ʻia ka hapalua hola ma mua o kahi pāʻina. Lawe ʻia ʻo Glucobai ma mua o ka ʻai ʻana, hiki ke ʻai ʻia me nā ʻāpana mua o ka meaʻai. Inā poina ka mea maʻi e lawe i ka lāʻau lapaʻau ma mua o ka papaʻaina, ʻae ʻia ia e lawe i ka lāʻau lapaʻau ma hope o ka ʻai ʻana, akā, ʻaʻole i hala ma mua o 15 mau minuke i hala.
I kekahi hihia, i ka manawa e poina ai ka mea maʻi e lawe i ka lāʻau hoʻokaʻa gula, ua papa ʻia i ka hoʻonui ʻana i ke ʻano o ka lāʻau lapaʻau i ka wā e hiki mai ana. Pono ʻoe e inu i ka maʻi wale nō o ka lāʻau lapaʻau i kuhikuhi ʻia e kāu kauka.
ʻO ka lawe ʻana i nā lāʻau lapaʻau haʻahaʻa i ka wā hāpai
I ka wā hapai, ua contraindicated ka hoʻohana ʻana o nā lāʻau i ke kō. No ka mea hiki iā lākou ke komo i ka plasenta i ka ʻōpū a loaʻa kahi hopena maikaʻi loa i ka hoʻolālā ʻana o ke keiki hānau ʻole. No kēia kumu, mālama ʻia ka maʻi diabetes i nā wahine hāpai e ka lawelawe ʻana i ka insulin a me ka hoʻohana ʻana i kahi ʻai therapeutic.
Inā loaʻa i ka wahine nā maʻi diabetes type 2 a ua mālama mua ʻia ia me nā lāʻau hypoglycemic ma mua, ua hoʻololi pinepine ia i ka insulin. Ma ka manawa like, hoʻokele ke kauka i ka mālama pono ʻana i ka mea maʻi; nā hoʻokolohua o ke koko a me nā wai paʻila e hana maʻamau. Kahi ʻia ka Insulin i loko o kēlā meā i lawe ʻia ai nā lāʻau lapaʻau haʻahaʻa.
Eia naʻe, ʻo ka mea nui ka hoʻomaʻamaʻa nui e hoʻoponopono i nā meaʻai a hoʻoponopono i ka papa hana.
ʻO kahi wahine hānai e maʻi ana i nā maʻi maʻi e hoʻopau i nā mea hou aʻe o 35 Kcal i ke kilokilo pākahi i kēlā me kēia lā. ʻO ka nui o ka Palekana i kēlā me kēia lā o ke kaupaona o ke kaumaha hiki ke piʻi i ʻelua grama, hōʻoki - 200-240 grama. ʻOi - 60-70 gram.
Pono pono e haʻalele piha i ka hoʻokomo o nā kalapika hoihoi wikiwiki, ʻo ia ka huahana o ka palaoa, semolina, confectionery, nā ʻeuʻeu. Ma kahi o ka pono, pono ʻoe e ʻai i nā meaʻai i loaʻa nā huaora o nā hui A, B, C, D, E, nā minelala a me nā mea kanu fib.
