ʻO ka formmetin ka lāʻau lapaʻau ikaika o ka metformin hydrochloride. Kāleka: 0,5 g; 0.85 g a i ʻole g g Analogs: Gliformin, Metadiene, Nova Met, NovoFormin, Siofor, Sofamet.
Nā huakaʻi kōkua: criumarmellose sodium; povidone momona molopole (polyvinylpyrrolidone), magnesium stearate no ka ʻoihana lāʻau lapaʻau.
E hoʻokuʻu i nā palapala: puni nā papa keʻokeʻo-cylindrical keʻokeʻo me ka facet a me kahi kuono (ke ʻano o ka 0.5 g) a me nā papa keʻokeʻo bvallex keʻokeʻo me ka pilikia o kekahi ʻaoʻao (ka dosage o 0.85 g a me 1.0 g).
Nā hōʻailona lapaʻau
Hoʻopau ka formethine i ka hoʻopili ʻana o ka glucose mai ka ʻōpū, pale i ke kaʻina o ka gluconeogenesis ma loko o ka ate, hoʻomaikaʻi i ka huapalapala huakaʻi peripheral, hoʻonui i ka ʻike ʻana o nā io i ka hoʻomākaukau ʻana i ka insulin.
I kēia hihia, formethine:
- ʻAʻole pili i ka hana ʻana o ka insulin e nā cell beta i loaʻa i ka pancreas.
- ʻAʻole ia e hoʻonāukiuki i ka hoʻolālā ʻana o kahi kūlana hypoglycemic.
- Hoʻemi i ka nui o nā lipoproteins haʻahaʻa haʻahaʻa a me ka triglycerides i ke koko.
- Hoʻemi i ka momona nui, hoʻopaʻa i ka paona maʻamau.
- Loaʻa ia he hopena fibrinolytic ma muli o ka kaohi o ka iwi plasminogen activator.
ʻO Formaline, ma hope o ka lawelawe waha, ua hoʻohemo iki ʻia mai ka gastrointestinal tract. ʻO ka nui o nā mea bioavailable ma hope o ka hoʻohana ʻana i kahi ʻano maʻamau ma kahi o 60%.
ʻO ka piʻi ʻana o ka hopena o ka lāʻau ma ke koko e loaʻa i nā hola 2.5 i hala o ka hoʻohana ʻana i loko.
ʻAʻole kokoke nā moloka i nā protein plasma; hōʻiliʻili i nā leʻaleʻa, nā pūpū, nā mākala, nā kelepa o ka salivary; ua hoʻopiʻi ʻia e nā ʻōpū ma kahi puka ʻole. ʻO ka hapalua wale o ka waiwai o ka 1.5 - 4.5 hola.
E makaʻala! Inā hana ka mea maʻi i ka hana renal, hiki ke hōʻiliʻili i ka lāʻau i ke kino.
Nā hōʻailona no ka hoʻohana ʻana
Ua hōʻike ʻia ka lāʻau lapaʻau no ka maʻi mellitus type 2, i ka wā ʻaʻole i lawe mai ka hānai meaʻai i nā hopena kūpono (i nā mea maʻi me ka huelo), hōʻike ʻia kēia mau mea a pau i nā ʻōlelo a ka lāʻau lapaʻau.
Hoʻolaha ʻia ka nui o ka lāʻau e ke kauka ponoʻī no kēlā me kēia maʻi. ʻO ka ʻokoʻa ma ka dosage ma muli o ke kaili ʻana o ka glucose i loko o ke koko. Pono e kiʻi ʻia nā papa formethine i ka manawa a ma hope iho o ka ʻai ʻana o ka mea maʻi i ka ʻai, me ka ʻaʻa ʻole a inu i ka nui o ka wai.
I ka hana mua o ka hoʻōla, pono ka ʻona he 0.85g. Ka manawa 1 i ka lā a i ka 0.5g paha. 1-2 mau lā i ka lā. E hoʻonui mālie i ka nui i 3g. i ka la.
Nui! No nā poʻe maʻi maʻi, ʻaʻole pono nā lula o kēlā me kēia lā e 1g. Ma muli o ke kūlana koʻikoʻi o ka acidosis lactic, me nā pathology metabolism koʻikoʻi, pono e hōʻemi ʻia ka ʻona.
Nā ʻōlelo kūikawā no ka hoʻohana ʻana
Nānā: i ka wā o ka mālama ʻana, pono ʻoe e hoʻomaʻamaʻa kūpono i ka hana ʻoi. I kēlā me kēia mahina ʻeono a me ka hoʻolālā ʻana o myalgia, pono ia e hoʻoholo i ka nui o ka lactate i ka plasma.
Hiki ke hoʻohana pū ʻia ʻo Formmetin i ka hui ʻana me nā derivatives o sulfonylurea. I kēia hihia, pono ka mālama ʻana i ka hoʻoliʻiliʻi o ke kō.
ʻAʻole hoʻopilikia ka pepa maʻamau i ka wā monotherapy e hiki ai ke hana me nā hana paʻakikī a hoʻokele i nā kaʻa. Inā hui pū ʻia ka lāʻau lapaʻau me nā lāʻau lapaʻau hypoglycemic ʻē aʻe, e pili ana paha ka hoʻomohala ʻana o ka hypoglycemia, i ʻole e hiki ke kaʻa i kahi kaʻa a hana pū me nā hana paʻakikī e koi nui i ka makaʻala.
ʻO nā hopena ʻino
Mai ka pūnaehana kinai:
- paila ʻaila;
- hemo wale, he luaa
- pāwīlū, ʻeha;
- lilo ka momona
- ʻeha ka ʻōpū.
Mai nā maʻi hemopoietic, i kekahi mau hihia ua ʻike ʻia nā anemia megalobast.
E pili ana i ka metabolism:
- koi i ke oki ʻana o ka mālama ʻana, ʻaʻole lactic acidosis;
- me ka lōʻihi o ka mālama ʻana, kūkulu ʻia ka hypovitaminosis B12.
ʻO ka ʻōnaehana endocrine i nā hopena hiki ʻole ke pane me ka hypoglycemia.
Hōʻike Allergic: ʻili kino.
Hoʻopili pū me nā lāʻau ʻē aʻe
Hiki ke hoʻonui ʻia ka hopena hypoglycemic o ka metformin i ka wā i hoʻohana pū ʻia me:
- insulin;
- kumuliiu aoli;
- Leikeleʻalani;
- acarbose;
- nā huahana-anti-inflammatory stidal;
- ʻoiʻuki;
- ka hoʻohuli ʻana i ka hoʻōla ʻana o nā enzyme;
- monoamine oxidase inhibitors;
- β-blockers;
- derivatives o clofibrate.
ʻO ka emi ʻana o ka hopena hypoglycemic o ka metformin e nānā ʻia me ka hoʻohana like ʻana me:
- hika a thiazide diuretics;
- nā hana hoʻohālikelike waha ʻole;
- glucocorticosteroids;
- kekona;
- epinephrine;
- nā hopena deriviazine;
- paeʻāina
- nā kinikini momona nikotinic;
- ʻO nā hormones thyroid.
Nā Hoʻohui
Mai lawe i FORMETINE me:
- pilikia hooili;
- diabetes ketoacidosis, precoma, coma;
- ka hanu a me ka hemahema;
- huki;
- pilikia ulia cerebrovascular;
- maʻi kūlohelohe a me nā kūlana ʻē aʻe e kōkua i ka hoʻomohalaʻana i ka hoʻomehana lactic acid;
- i ka wā hāpai a me ka lactation;
- hypersensitivity i nā māhele o ka lāʻau lapaʻau;
- nā hōʻeha a me nā hana hōʻiliʻili koʻikoʻi;
- maʻi ʻino loa;
- lilo i ka palaka hoʻohuihā wai;
- lactic acidosis.
ʻO ka ʻōlelo a ke kau nei, ʻaʻole pono ka mua o ka hoʻohana ʻana o Formmetin e ka mea noiʻi o ka radiological a me nā radioisotope me ka hoʻomaka ʻana o nā mea i ʻike ʻia i ka iodine i loko o 2 mau lā.
ʻAʻole paipai ʻia ʻo Formethine no ka hoʻohana ʻia e nā poʻe ma luna o 60 e hana i ka hana kino kino. Inā ʻaʻole mālama ʻia kēia lula, hiki i nā mea maʻi ke hoʻomohala i ka acidosis lactic.
ʻO ka ʻōlelo a ka overdose e ʻōlelo ai
Hoʻomaopopo nā ʻōnaehana no ka lāʻau lapaʻau Formmetin me ka overdose, aia hiki ke hoʻomohala i ka acidosis lactic me kahi hopena momona. ʻO ke kumu o kēia kūlana ka mea e hōʻiliʻili i ka lāʻau i loko o ke kino ma muli o ka hana renal impaired.
ʻO nā hōʻailona ʻehā ka hōʻailona mau o ka lactic acidosis:
- La mualoa, haahaa.
- Nā huapō, nā ʻeha o ka ʻōpū.
- ʻO ka nāwaliwali, hypothermia.
- ʻʻAla
- ʻEha nā naʻau.
- Hōʻike i ka bradyarrhythmia.
- Ke hoʻohaʻahaʻa nei i ke koko.
- Hoʻohui a me ka hoʻomohala ʻana i ka coma
Inā loaʻa i ka mea maʻi ka hōʻailona maʻamau o ka lactic acidosis, haʻalele koke ʻia ʻo Formin mai nā lāʻau lapaʻau, pono e hoʻihoʻi koke ka mea maʻi i kahi haukapila kahi e hiki ai i ke kauka ke hoʻoholo i ke kūpaʻa o ka lactate a hana i kahi maʻi unmistakable.
Ke hopena maikaʻi loa e kāpae nei i ka metformin a me ka lactate mai ke kino aku ʻo ka hemodialysis, me ka mea e hoʻokō ʻia ai ka mālama maʻi.
Kūpono - kūʻai, kūʻai
ʻO ka hala o ke ola o ka lāʻau lapaʻau he 24 mau mahina, ma hope o ʻaʻole hiki ke hoʻohana ʻia iā Formula. Aia ka lāʻau i ka papa inoa B. Pono e mālama ʻia i kahi wahi pouli i hiki ʻole i ka poʻe keiki ke mālama i ka nui o ke kiʻekiʻe o 25 ° C
Mea hana - Pharmstandard.
E hoʻokuʻu i nā puka - nā papa o 850 mg. 60 ʻāpana.
Kūʻai - 177 mau rubles.
Mea hana - Pharmstandard.
Hoʻokuʻu i nā palapala - papa 1gr. 60 ʻāpana.
Kumukūʻai - 252 rub.
ʻOi aku nā kumukūʻai hou.
