Ua komo ka lāʻau lapaʻau hou i ka hoʻohana ʻana i ʻelua mau ʻano o ka insulin: e uhi i nā pono kumu a e uku hou i ka honi ma hope o ka ʻai ʻana. I waena o nā lāʻau lapaʻau me ka hana hoʻoweliweli a i waena paha, ʻo ka lālani mua o ka mana i noho ʻia e ka insulin Protafan, ʻo ia ka mākeke ma kahi o 30%
ʻO ka mea hana, ʻoihana Novo Nordisk, kaulana i ka honua i ka hakakā i ka maʻi maʻi. Mahalo i kā lākou noiʻi, ʻike ʻia ka insulin ma kahi mamao loa me ka hana lōʻihi, ka mea i hiki ai i ka hoʻomaʻamaʻa nui ʻana i ke ola o nā maʻi. He kiʻekiʻe kiʻekiʻe o ka hoʻomaʻemaʻe ʻana ʻo Protafan, paʻa a ʻike ʻia.
ʻ .lelo pōkole
Kuhi ʻia ʻo Protafan ma kahi ʻano biosynthetic. ʻO ka DNA e pono ai no ke kāpili ʻana i ka insulin e hoʻokomo ʻia i loko o nā microorganism huehue, ma hope o lākou e hoʻomaka ai e hana i ka proinsulin. ʻO ka insulin i loaʻa ma hope o ka mālamaʻana i ka enzymatic e like like me ke kanaka. E hoʻolōʻihi i kāna hana, ua kāwili ʻia ka hormone me ka protamine, a ke kāhea ʻia nei lākou me ka hoʻohana ʻana i ʻenehana kūikawā. Hōʻike ka lāʻau lapaʻau i kēia ala me kahi pūnaehana maʻamau, hiki iā ʻoe ke maopopo inā ʻaʻole e hoʻopilikia ʻia ka loli i ka pahu. No ka poʻe maʻi, he mea nui kēia: ʻo ka mea liʻiliʻi e hoʻopili i ka hana o ka insulin, ʻoi ka uku ʻoi aku ka maikaʻi no ka maʻi diabetes.
| ʻO keʻano | ʻO Protafan, e like me nā insulins NPH āpau, e hoʻopili i kahi vial. Aia ma lalo kahi loaʻa i kahi keʻokeʻo keʻokeʻo, ma luna - kahi wai translucent. Ma hope o ke kāwili ʻana, lilo ke ʻano holoʻokoʻa i keʻokeʻo a keʻokeʻo. ʻO ka paʻa ʻana o ka hana ikaika he 100 mau pūʻulu no ka milliliter. |
| E hoʻokuʻu i nā palapala | Loaʻa ka Protafan NM i loko o nā pahu aniani me ka 10 ml o ka hoʻonā. I kēia palapala, loaʻa nā lāʻau lapaʻau e nā lāʻau lapaʻau a me nā maʻi maʻi i kaʻi ʻana i ka insulin me kahi syringe. I loko o kahi pahu pahu 1 pahu a me nā kauoha no ka hoʻohana. ʻO Protafan NM Penfill he 3 ml mau kāleka i hiki ke hoʻokomo i nā penikala syringe no NovoPen 4 (kahi mahele papa 1) a i ʻole NovoPen Echo (hana mahele. No ka hoʻouluuluʻana i ke kāwili ʻana i kēlā me kēia pahu kāwele i ka pōpoki aniani. ʻO ka pepa i ka 5 mau pahu pahu a me nā ʻōlelo aʻoaʻo. |
| Hōʻike | ʻO ka mea hoʻōla ikaika o ka insulin-isophan, kōkua: ka wai, protamine sulfate e hoʻolōʻihi i ka lōʻihi o ka hana, phenol, metacresol a me nā zinc ʻona e like me ke mālama i ka wai, nā mea e hoʻoponopono ai i ka acidity o ka hopena. |
| Hoʻolaha | ʻO ka hoʻemi ʻana i ke kōpaʻa koko ma ke kaʻa ʻana aku i nā ʻili, hoʻonui i ka synthesis glycogen i nā musina a me ka puʻuwai. Hoʻokomo ia i ka hoʻokumuʻana o nā protein a me nā momona, no laila ke hāʻawi nei i ka loaʻa kālā. Hoʻohana ʻia ka mālama ʻana i ke kō mauʻai maʻamau: ma ka pō a ma waena o ka pāʻina. ʻAʻole hiki ke hoʻohana ʻia ʻo Protafan e hoʻoponopono i ka glycemia, nā insulins pōkole e pono no kēia mau kumu. |
| Nā Hōʻike | ʻO ka maʻi diabetes mellitus i nā maʻi e koi ana i ka hoʻomehanaʻana o ka insulin, ʻaʻohe o nā makahiki. Me nā maʻi type 1 - mai ka hoʻomaka ʻana o nā pilikia o ka paʻakai, me ka ʻano 2 - i ka manawa ʻaʻole i lawa nā pulu haʻahaʻa a me ke kō, a ʻo ka hemoglobin glycated iʻoi aku ma mua o 9%. ʻO ka maʻi diabetes gestational i nā wahine hāpai. |
| Koho koho | ʻAʻole i nā ʻōkuhi ka dosage i ʻōlelo ʻia ʻia, ʻoiai ka nui o ka insulin i koi ʻia no nā maʻi maʻi like ʻole e ʻokoʻa. Hoʻonohonoho ʻia ia ma ke kumu o ka wikiwiki o ka ʻike glycemia. Koho ʻia ka make ʻana o ka inehina no ke kakahiaka a me ke ahiahi - ka helu ʻana o ka maʻi o ka insulin no nā ʻano ʻelua. |
| Hoʻoponopono i ka helu | Hoʻonui ka pono i ka insulin me ka pīhoihoi o ke kino, ke kino a me ka noʻonoʻo, ka ʻeha, a me nā maʻi maʻi maʻi. ʻAʻole pono ke hoʻohana ʻana i ka waiʻona i ka maʻi diabetes, me ka hoʻomaikaʻi ʻana i ka hoʻēmi ʻana o ka maʻi a hiki ke hoʻonāukiuki i ka hypoglycemia koʻikoʻi. Pono ʻia ka hoʻoponopono ʻia ʻana ma ka wā e lawe ai i kekahi lāʻau lapaʻau. Hoʻonui - me ka hoʻohana ʻana o ka diuretics a me kekahi mau lāʻau lāʻau hormonal. ʻO ka hōʻemi - i ka ʻoi o ka hoʻokō i ka hui me nā papa hoʻohaʻahaʻa i ke kō, nā tetracycline, aspirin, nā lāʻau lapaʻau antihypertensive mai nā pūʻulu o nā mea pale aku o AT1 a me nā mea hoʻouluhua ACE. |
| Nā hopena hopena | ʻO ka hopena maʻamau e pili ana i ka insulin i ka hypoglycemia. Ke hoʻohana nei i nā lāʻau lapaʻau NPH, ʻoi aʻe ka nui o ka hāʻule o ke kō i ka pō, ʻoiai ua kiʻekiʻe lākou i ka hana. ʻO ka hypoglycemia Nocturnal e pōʻino loa i ka maʻi mellitus, no ka mea, ʻaʻole hiki i ka mea maʻi ke maʻi a hoʻonele iā lākou iho. ʻO ka haʻahaʻa haʻahaʻa i ka pō, ʻo ia ka hopena o kahi nui i koho ʻia ʻole a i ʻole kahi ʻano metabola kū hoʻokahi. ʻOi aku ka liʻiliʻi o 1% o nā maʻi maʻi, ka insulin Protafan e hoʻohālikelike i ka maʻi kūloko kūloko kūlike i ke ʻano o kahi hōʻeha, kahe, a me ka pupuhi i ka pūnaewele i hoʻopaʻa ʻia. ʻO ka hopena o nā maʻi maʻi maʻamau ākea hoʻi ma lalo o 0.01%. ʻO nā loli i ka momona subcutaneous, lipodystrophy, hiki paha i nā hanana. Ke kiʻekiʻe ko lākou lamina inā ʻaʻole i hahai ʻia ke ʻōkuhi. |
| Nā Hoʻohui | ʻAʻole pāpā ʻo Protafan e hoʻohana i loko o ka poʻe maʻi me ka mōʻaukala o allergy a me ka edema Quincke no kēia insulin. Ma kahi e koho ai, ʻoi aku ka maikaʻi o ka hoʻohana ʻole ʻana o nā insulins NPH me kahi māhele like, akā hui pūhia insulin - Lantus a i Levemir paha. ʻAʻole pono e hoʻohana ʻo Protafan e nā maʻi maʻi maʻi me ka makemake i ka hypoglycemia, a inā i hoʻokaʻawale paha kāna mau hōʻailona. Ua ʻike ʻia he mea palekana loa nā analog analog i kēia hihia. |
| Laki | Pono i ka pale mai ka māmā, ka wela wela a me ka mahana (> 30 ° C). Pono e mālama i nā kīʻaha i loko o kahi pahu, insulin i loko o nā ʻāpana syringe pono e pale ʻia me ka pāpale. I ka wā wela, e hoʻohana ʻia nā mea hoʻonaninani kūikawā e halihali ai iā Protafan. ʻO nā kūlana maikaʻi loa no ka mālama lōʻihi (a hiki i 30 mau pule) he hale papa paha a i ʻole kahi pahu friji. I ka lumi lumi, ʻo Protafan i loko o ke ʻano hoʻomaka i mau no 6 mau pule. |
ʻOikepili hou e pili ana iā Protafan
Aia ma lalo iho nā ʻike pili āpau e pili ana i ka lāʻau lapaʻau.
He manawa hana
ʻO ka helu o ke komo ʻana o ka Protafan mai ka subcutaneous tissue i loko o ke kahe koko i loko o nā mea maʻi me ka maʻi maʻi ʻokoʻa, no laila hiki ʻole ke kikoʻī pololei i ka wā e hoʻomaka ai ka hana o ka insulin. ʻIkepili pane
ʻO ka maʻi maʻi a me nā hoʻohaʻahaʻa manaʻo e hana ia i ka wā ma mua
- Ka hana maʻamau o ke kō -95%
- Hoʻokuʻuina o ka pua thrombosis - 70%
- Hoʻopau i kahi puʻuwai ikaika -90%
- Hoʻopau i ke kiʻekiʻe o ke koko - 92%
- ʻO ka hoʻonuiʻana i ka ikehu i ka wā, hoʻomaikaʻi i ka hiamoe i ka pō -97%
- Mai ka hōʻike i ke ʻano o ka hormone i loko o ke koko, e pili ana i nā hola 1,5.
- He hana koʻikoʻi ʻo Protafan, ma ka hapa nui o nā maʻi maʻi i loaʻa i nā hola 4 mai ka manawa o ka hoʻokele.
- Loaʻa ka lōʻihi o ka lōʻihi o ka hana 24 mau hola. I kēia hihia, ʻike ʻia ka hilinaʻi o ka lōʻihi o ka hana ma ke ʻano. Me ka hoʻomakaʻana o 10 mau pūʻulu o ka Protafan insulin, e nānā ʻia ka hopena o ke kōpaeʻai ma kahi o 14 mau hola, he 20 mau hola no ka mau hola 18.
Iā ke hoʻoponopono hoʻonā
I ka hapanui o nā maʻi me ka maʻi diabetes, ua lawa kekahi manawa ʻelua ʻo Protafan: i ke kakahiaka a ma mua o ka hiamoe ʻana. Pono e hoʻolako i kahi kōkau ʻia no ka mālama ʻana i ka glycemia a puni ka pō.
Nā paila no ka inika kūpono:
- ʻO ke kōʻai i ke kakahiaka e like me ka mea e moe ai;
- ʻaʻohe hypoglycemia i ka pō.
ʻO ka pinepine, ʻoi ka piʻi ʻana o ke kō o ke koko ma hope o 3 kakahiaka, i ka wā e ikaika ai ka hana o nā hormone contrainsular, a ua nāwaliwali ka hopena o ka insulin. Inā pau ka hopena o ka Protafan ma mua, he pōpilikia olakino ia ʻole: unrecognised hypoglycemia i ka pō a me ke kō o ka wai i ke kakahiaka. I mea e pale aku ai, pono ʻoe i ka nānā maʻamau i nā pae kō i ke kō he 12 a me 3 mau hola. Hiki ke hoʻololi ʻia ka manawa o ke kaʻina ahiahi.
Nā hiʻohiʻona o ka hana o nā liʻiliʻi liʻiliʻi
Me nā maʻi diabetes type 2, kahi maʻi maʻi gestational o nā wahine hāpai, i nā keiki, i nā pākeke ma kahi papaʻai haʻahaʻa-liʻiliʻi, liʻiliʻi ka pono o ka insulin NPH. Me kahi liʻiliʻi liʻiliʻi (a hiki i nā ʻāpana 7), hiki ke lōʻihi ka lōʻihi o ka hana a Protafan ma 8 mau hola. ʻO kāna kumu, ʻaʻole lawa ka nui o nā inikua ʻelua i hāʻawi ʻia ma ke ʻano, a ma waena o ka hoʻonui ʻana o ke kō koko.
Hiki ke pale i kēia ma ka ʻae ʻana i ka insulin Protafan 3 mau manawa i kēlā me kēia 8 mau hola: ke hāʻawi mua ʻia nei ka inikua mua ma hope o ke ala ʻana, ʻo ka lua i ka wā awakea me ka insulin pōkole, ʻo ʻekolu ka mea nui loa, ma mua o ka hiamoe ʻana.
ʻO nā loiloi maʻi maʻi, ʻaʻole kūleʻa nā mea a pau e hoʻokō ana i kahi uku hoʻonaninani no ka maʻi diabetes ma kēia ʻano. I kekahi manawa e oki ka hana ʻana o ka pō ma mua o ke ala ʻana, a kiʻekiʻe ke kō. ʻO ka hoʻonui ʻana i ka huakaʻi e alakaʻi ana i ka overdose o ka insulin a me ka hypoglycemia. ʻO ke ala wale nō i waho o kēia kūlana ke hoʻololi ʻana i nā analog analog me ka lōʻihi o ka hana.
Mea ʻai kai
Hoʻololi pinepine ʻia nā maʻi maʻamau i ka hui i ka insulin a i ka minamina a i ʻole ka pōkole. Pono pono kahi hoʻohaʻahaʻa i ka haʻahaʻa glucose e komo i ke kahe wai mai ka meaʻai. Hoʻohana ʻia nō hoʻi ia e hoʻoponopono i ka maʻi glycemia. I ʻoi aku me ka Protafan ʻoi aku ka maikaʻi e hoʻohana i kahi hoʻomākaukau pōkole o ka mea hana like - Actrapid, ʻo ia hoʻi i loaʻa i nā pahu kiki a i nā pahu penikala no nā syringe.
ʻO ka manawa o ka noho ʻana o ka insulin Protafan, ʻaʻole ia e hilinaʻi i nā mea ʻai ma kekahi ala, ma kahi o ke kīʻaha like ma waena o nā injections e lawa. Ke koho nei ʻoe i kahi manawa kūpono, pono ʻoe e kāhiko mau iā ia. Inā kūpono me ka meaʻai, hiki i ka Protafan ke hoʻohui ʻia me ka nui o ka insulin. Ma ka manawa like ke kāwele ʻana iā lākou i loko o nā syring like like ʻole i kūpono ʻole ʻia, no ka mea, he kuhi hewa paha me ka hoʻēmi ʻana a lohi i ka hana o ka hormone pōkole.
ʻĀlia nui loa
Ma ka maʻi mellitus, pono ʻoe e hoʻokomo i ka insulin e like me ka mea e pono ai no ka hoʻomaʻamaʻa i ka glucose. Ke aʻo ʻana no ka hoʻohana ʻana i ka palena kiʻekiʻe loa ʻaʻole i hoʻokumu. Inā e ulu pono ana ka nui kūpono o ka Protafan insulin, e hōʻike paha i kēia ke kū i ka insulin. Me kēia pilikia, pono e nīnau ʻoe i kāu kauka. Inā kūpono, e kākau ʻo ia i nā lāʻau e hoʻomaikaʻi i ka hana o ka hormone.
Hoʻohana ʻia
Inā me kahi maʻi maʻi gestational hiki ʻole ke hoʻokō kūlike i ka glycemia maʻamau ma o kaʻai ʻana i ka meaʻai, ua hāʻawi ʻia nā mea maʻi i ka insulin insulin. Ua koho pono ʻia ka lāʻau lapaʻau a me kāna ʻano momona, no ka mea, ua hoʻonui ʻia ka ʻelua o ka hyp- a me ka hyperglycemia i ka ʻike ʻana o ke kolohe ʻana o ke keiki. ʻAe ʻia ka Insulin Protafan no ka hoʻohana ʻana i ka wā hāpai, akā i ka hapa nui, e ʻoi aku ka lōʻihi o nā analogues.
Inā hele mai ka hapai me ka maʻi type 1, a hoʻopaʻi ka wahine i ka maʻi ʻo Protafan, ʻaʻole pono kahi loli o ka lāʻau lapaʻau.
E hele maikaʻi ka male ʻana me ka inika insulin. ʻAʻole e hana ʻo Protafan i ka pōʻino i ke olakino pēpē. Hoʻomoʻa ka Insulin i ka waiū i ka liʻiliʻi liʻiliʻi, ma hope o ka nahā i ka hoʻokaʻawale ʻana i ke keiki o ke keiki, e like me nā mea ʻē aʻe.
ʻO ka analogs Protafan, e hoʻohuli ana i kekahi insulin
ʻO nā mea kikoʻī piha o Protafan NM me nā mea like a me ka manawa hana kokoke e waiho:
- ʻO Humulin NPH, USA - ka mea hoʻokūkū nui, loaʻa i ka mahele o ke mākeke ma mua o 27%;
- Insuman Bazal, Farani;
- Biosulin N, RF;
- Rinsulin NPH, RF.
Mai ka nānā ʻana i ka lāʻau lapaʻau, ʻo ka loli o Protafan i kekahi lāʻau lapaʻau NPH ʻē aʻe, ʻaʻole ia he hoʻololi i kekahi insulin, a ʻoiai i loko o nā kiʻi i hōʻike ʻia i ke ʻano ikaika wale nō, ʻaʻole ia he hōʻailona kūikawā. Ma ka hoʻomaʻamaʻa, hiki i kahi mea hoʻonaninani ke hiki ke hōʻola wale i ka mālama glycemic pōkole a koi aku i ka hoʻoponopono ʻōpiopio, akā hoʻonāukiuki i nā maʻi allies. Inā he maʻamau ka glycated hemoglobin a ua nānā pinepine ʻia ka hypoglycemia, ʻaʻole ʻia ke kānana ʻana i ka insulin Protafan.
Nā ʻokoʻa o ka analogue insulin
ʻO nā analog analog lōʻihi, e like me Lantus a me Tujeo, ʻaʻohe ōpū, ʻoi aku ka maikaʻi o ka hoʻokaʻawale ʻana i nā mea maʻi. Inā he maʻi diabetes ka nogturnal hypoglycemia a me nā wai kōpaʻa no kekahi kumu, pono e hoʻohuli ʻo Protafan me nā insulins lōʻihi.
ʻO kā lākou hōʻino nui loa ka uku kiʻekiʻe. ʻO ke kumu o Protafan he 400 mau rubles. no kahi pahu a me 950 no ka hoʻopili ʻana i nā pahu kāwili no nā peni syringe. ʻO nā aneila Insulin ka aneane 3 mau manawa hou aku.
