ʻO Microalbuminuria (MAU) ka hōʻailona mua o ka hana renal impaired, ka mea i hōʻike ʻia e ka nui o ka nui o ka protein i loko o ka iomi. ʻO nā protein e like me ka albumin a me nā immunoglobulins e kōkua i ka hoʻopio ʻana i ke koko, ke kaupaona ʻana i nā kahe wai i loko o ke kino a kaua i ka maʻi ʻana.
Lawe ke kauka i nā mea makemake ʻole mai ke koko ma o nā miliona o ka kānana glomeruli. He nui loa ka hapa nui e pale i kēia pā. Eia ka mea e haki ai ka glomeruli, hele ka protena i loko o lākou a komo i ka urine, a hōʻike kēia i kahi loiloi no microalbumin. ʻOi aku ka pilikia o ka poʻe me ka maʻi maʻi a i ʻole ka maʻi hypertension.
He aha ka microalbumin?
ʻO Microalbumin kahi protein i pili i ka hui o albumin. Aia ia i loko o ke akea a laila lele i ka koko. ʻO ka palu kahi kānana no ka ʻōnaehana kao, hoʻoneʻe i nā mea ʻeha (nā waihona nitrous), nā mea i hoʻouna ʻia i ka wahi ʻino i ke ʻano o ka urine.
Kuhi pinepine kahi kanaka olakino i kahi kaila liʻiliʻi loa i loko o ka pāʻai, ma ka kikoʻī i hōʻike ʻia e hōʻike ana i kahi helu (0,033 g) a i ʻole ka huaʻōlelo ʻo "he wahi o ka protein ka mea i loaʻa" i kākau ʻia.
Inā ua hōʻino ʻia nā kīʻaha koko o nā keiki, a laila nalowale hou ka nui o ka protein. Ke alakaʻi aku nei kēia i ka hōʻiliʻiliʻana o ka wai i loko o ka lumi intercellular - edema. ʻO Microalbuminuria kahi hōʻailona i ka wā mua o kēia hana ma mua o ka hoʻomohala ʻana i nā hōʻike lapaʻau.
Nā hōʻailona noiʻi - nūpepa a me nā patology
I ka poʻe me ka maʻi maʻi, ʻike pinepine ʻia ka UIA ma ka hōʻike lāʻau lapaʻau maʻamau. ʻO ka hana maʻalahi o ke aʻoʻana ka hoʻohālikelike o ka ratio o ka albumin a me ka mea hana i ka iomi.
ʻO ka papa ʻaina o nā hōʻailona maʻamau a me nā kulekele helu:
Kakauolelo | Kāne lāʻau | Kukuluʻala |
---|---|---|
Kau kāne | ʻOi aku a emi a like me 2,5 mg / μmol | > 2.5 mg / mol |
Wahine wahine | ʻOi aku a emi a like me 3,5 mg / μmol | > 3,5 mg / μmol |
ʻO ka hōʻailona o ka albumin i ka urine, ʻaʻole pono e kiʻekiʻe aʻe ma mua o 30 mg.
No ka hoʻokaʻawaleʻana o nā maʻi o ka pūpū a me ka nephropathy diabetes, ʻelua hana hōʻike. No ka mea mua, hoʻohana ʻia kahi tauira urine a ʻike ʻia kahi pae o ka protein. No ka lua, lawe lākou i ke koko a nānā i ka helu filtration glomerular o nā keiki.
ʻO ka nephropathy Diabetic kekahi o nā hoʻopiʻi pinepine ʻana o ka maʻi diabetes, no laila he mea nui ia e hoʻokau ʻia ma ka liʻiliʻi ma mua o hoʻokahi makahiki. ʻO ka wikiwiki koke ʻia, ʻoi aku ka maʻalahi o ka mālama ʻana ma hope.
Nā kumu kumu o ka maʻi
ʻO Microalbuminuria kahi hoʻopiʻi kūpono i ka ʻano 1 a i ʻole ka type 2 diabetes mellitus, ʻoiai ke kāohi maikaʻi ʻia. Ma kahi o kahi i ʻelima mau kānaka me ka maʻi o ka maʻi hānai e ulu ana i ka UIA i loko o 15 mau makahiki.
Akā aia kekahi mau mea kūpono e hiki ai i ke microalbuminuria:
- haʻi maʻi
- kaumaha nā moʻolelo ʻohana o ka hoʻomohala ʻana i ka nephropathy maʻi;
- ulaula;
- momona;
- nā maʻi o ka pūnaehana cardiovascular;
- gestosis hopena i nā wahine hāpai;
- nā hana hōʻeuʻeu o nā keiki;
- pyelonephritis;
- glomerulonephritis;
- amyloidosis;
- Hoʻopiʻi ʻo IgA.
Nā hōʻailona o ka microalbuminuria
I nā wā mua, ʻaʻohe hōʻailona ʻole. I nā wā ma hope, a i ʻole ka hana ʻana o nā keiki me ka hana me ka hoʻomaʻamaʻa, hiki iā ʻoe ke ʻike i nā loli i ka urine a hoʻomaopopo i ka nānā ʻana o ka edema.
Ma keʻano holoʻokoʻa, hiki ke hoʻomaopopo ʻia i nā hōʻailona koʻikoʻi:
- Hoʻololi i loko o ka urine: ma muli o ka hoʻonui i ka protein excretion, hiki i ka mehameha ka mea hana.
- ʻO ka maʻi Edema - kahi hoʻohaʻahaʻa i ka pae o ka albumin i ke koko ke kumu o ka mālamaʻana i nā wai a me ka pupuhi, kahi i ʻike nui ʻia i nā lima a me nā wāwae. I nā hihia koʻikoʻi ʻoi aku paha, piʻi a piʻi paha ke ʻano o ka maka.
- Ka hoʻonui ʻana i ke koko - aia ka nalowale ʻana o ke kahe mai ke kahe ana o ke kahawai a, ma muli o kēia, ke kūwi nui ʻia ke koko.
Hōʻikeʻike Physiological
Hoʻokumu nā hōʻailona phologicalological i ke kumu o microalbuminuria.
E pili ana kēia:
- ʻeha i ka hapa hema o ka umauma;
- ʻeha i ka ʻāina lumbar;
- hana ʻino o ke olakino maʻamau;
- tinnitus;
- lie kanikela
- nāwaliwali o ke kino;
- makewai
- ka lele ana e kailua ana i mua o na maka;
- maloʻo maloʻo;
- mea kaumaha
- ʻilihune maikaʻi ʻole ʻole;
- anemia
- ʻeha hōʻeha a me nā mea ʻē aʻe.
Pehea e hōʻiliʻili ai i ka nānā ʻana?
Pehea e kau ai i ka urine no ka nānā ʻana kekahi o nā nīnau nīnau pinepine i kahi kauka.
Hiki i kahi hōʻike albumin ke hana ma kahi palapala he aihue e ʻohi ʻia:
- ma ka laiki, maʻamau i ke kakahiaka;
- ma luna o kahi 24 hola;
- i ka manawa o kekahi manawa, no ka manawa he 16.00 pm.
No ka hoʻoiliʻana, pono ʻia kahi hapa o ka urine. Hāʻawi ke kakahiaka i ka ʻike maikaʻi loa e pili ana i ka pae o ka albumin.
He hōʻike maʻalahi ka hōʻike UIA. ʻAʻole pono ka hoʻomaʻamaʻa kūikawā no ia. Hiki iā ʻoe ke ʻai a inu hoʻi e like me ka maʻamau.
ʻĀina no ka ʻohi ʻana i ka wī kakahiaka kakahiaka:
- Holoi i kou mau lima.
- Hoʻopau i ka pale mai ka pahu hopu, e kau i ka ʻaoʻao o luna. Mai hoʻopili i kou ʻāpana me kou mau manamana lima.
- E hoʻomaka i ka uring i ka lua, a laila hoʻomau i loko o ka ipu hōʻike. E hōʻiliʻili e pili ana i 60 ml o ka urine medium.
- I loko o hoʻokahi hola a i ʻole ʻelua, pono e hāʻawi ʻia ka nānā ʻana i ka ʻenehana no ka noiʻi.
E hōʻiliʻili i ka urine ma luna o kahi 24-hola, mai hoʻopakele i ka hapa mua o ka urine kakahiaka. Ma kahi o 24 mau hola e hiki mai ana, e hōʻiliʻili i ka urine a pau i kahi pahu kīʻaha kūikawā e pono ai ke mālama i ka pahu i loko o kahi lā.
Ke kau nei i nā hopena:
- ʻOi aku ma mua o 30 mg o ke ʻano.
- Mai 30 a 300 mg - microalbuminuria.
- ʻOi aku ma mua o 300 mg - macroalbuminuria.
Nui kekahi mau hiʻohiʻona pili i ka hopena o ka hōʻike (pono lākou e noʻonoʻo).
- hematuria (koko i loko o ka urine);
- fiva
- hoʻoikaika kino hou;
- huki;
- maʻi maʻi maʻi urinary.
Hiki i kekahi mau lāʻau ke hoʻopilikia i nā pae albumin urinary:
- nā antibiotika, me ka aminoglycosides, cephalosporins, penicillins;
- antifungal lāʻau (Amphotericin B, Griseofulvin);
- Penicillamine;
- Phenazopyridine;
- salicylates;
- Tolbutamide.
Nā wikiō mai Kauka Malysheva e pili ana i nā hōʻailona o ka nānā ʻana i ka urine, kā lākou helu a me nā kumu o nā loli.
Hoʻohana ʻia
ʻO ka Microalbuminuria kahi hōʻailona i kau pilikia i ka hoʻomohala ʻana i nā kūlana koʻikoʻi e pili ana i ka ola, e like me ka maʻi maʻi a me ka maʻi ʻalā. ʻO ia ke kumu he mea nui loa ka hoʻoponopono ʻana i kēia pathology i kahi papa mua.
ʻO Microalbuminuria kekahi manawa i kapa ʻia "nephropathy mua", no ka mea hiki ke hoʻomaka o ka maʻi nephrotic.
Ma ka maʻi mellitus me ka UIA, pono ia e hoʻokau i nā hōʻike i hoʻokahi manawa i kēlā me kēia makahiki e nānā ai i kou kūlana.
Hiki i nā lāʻau lapaʻau a me nā loli ke ola e kōkua i ka pale ʻana o ka hōʻino hou o ka keiki. Hiki iā ia ke hōʻemi i ka hopena o nā maʻi o ka ʻōnaehana cardiovascular.
Nā manaʻo e hoʻololi ai i ka nohona.
- hana maʻamau (150 mau minuke i kēlā me kēia pule o ka ikaika);
- pipiʻi i kahi meaʻai;
- hele aku i ka ulaula (me nā hua kikowaena uila);
- ke ʻoki ʻana i ka ʻona;
- nānā i ke kō koko a inā ke hoʻokiʻekiʻe nui, e nīnau koke i kahi kauka.
Me ke koko o ke koko, ua kau ʻia nā hui like ʻole no ka hypertension, ʻoi aku ka nui o nā angiotensin-hoʻohuli o ka enzyme (ACE) inhibitors a me ka angiotensin II receptor blockers (ARBs). He mea nui ko lākou kumu no ka hoʻonui ʻana i ke koko kiʻekiʻe i ka hoʻomohala ʻana i ka maʻi ʻōpiopio.
Hiki ke hiki i ka microalbuminuria kahi hōʻailona o ka hōʻino i ka ʻōnaehana cardiovascular, no laila hiki i ke kauka hele hele aku ke kuhikuhi i nā statins (Rosuvastatin, Atorvastatin). Ke hōʻemi nei kēia mau lāʻau i ka kolesteroli, a laila e hōʻemi ai i ka hōʻeha ʻana o ka puʻuwai a i ʻole hōʻeha paha.
I mua o edema, diuretics, no ka laʻana, ʻo Veroshpiron, hiki ke kuhikuhi.
I nā kūlana koʻikoʻi me ka hoʻolālā ʻana o ka maʻi maʻamau, ʻo ka hemodialysis a i ʻole hoʻololi ʻia ke akeʻa. I kekahi hihia, pono e mālama i ka maʻi lalo e hōʻoli ana i ka proteinuria.
E kōkua ka ʻai momona i ka hoʻoluliluli i ka holomua o ka microalbuminuria a me nā pilikia o ka pōpilikia, ʻoiai inā e hoʻohaʻahaʻa ana i ke koko, a me ka pale ʻana i ka momona.
Ma keʻano kūikawā, he mea nui e hoʻemi i ka nui o:
- momona momona;
- paʻakai;
- nā meaʻai kiʻekiʻe i ka protein, sodium, potassium a me ka phosphorus.
Hiki iā ʻoe ke kiʻi i nā kūkākūkā kikoʻī loa i ka meaʻai mai kahi endocrinologist a i ʻole i ka mea iʻai olakino paha. ʻO kou mālama ka ala i hoʻohui ʻia a he mea nui loa ia e hilinaʻi ʻaʻole wale i nā lāʻau lapaʻau.