ʻO ka Blocktran GT kahi lāʻau lapaʻau pinepine i kauoha ʻia no ke koko kiʻekiʻe. ʻO ke koi nui no kēia lāʻau lapaʻau ma muli o ka maʻalahi kūpono a me ke ʻano haʻahaʻa.
Inoa Kūʻai ʻole honua
ʻO ka inoa inoa inoa holomua no ka lāʻau ʻo Losartan.
ʻO ka Blocktran GT kahi lāʻau lapaʻau pinepine i kauoha ʻia no ke koko kiʻekiʻe.
ATX
E like me ka helu o nā lāʻau, ATX: C09DA01.
Ua hui pū ʻia ʻo Losartan me nā diuretics.
E hoʻokuʻu i nā palapala a me ka ʻano
Hoʻokuʻu ʻia ka lāʻau lapaʻau ma ke ʻano o nā papa pōkole, kēlā me kēia me ka pākuʻi ʻia hoʻi. Hiki i ka kala o ke kinipula he ulaula, aia kahi ʻolō poni.
I ka hoʻonohonohoʻana o ka lāʻau lapaʻau, ka hana nui o ka mea ikaika i hana:
- pāhare pāpaho losartan;
- huinahui.
ʻO ka papa inoa o nā mea kōkua hoʻohui;
- mikulamulamina selulose;
- lactose monohala;
- kalaka ʻaʻa;
- povidone;
- magnesium stearate;
- sodium starch glycolate;
- colloidal sililikone.
ʻO ka paʻakikī o losartan a me ka hydrochlorothiazide e hoʻopuka i ka hoʻohaʻahaʻa i ke koko.
Nā ʻāpana papa ʻokoʻa ma ia mau ʻano:
- polydextrose;
- huki;
- talc;
- medium chain triglycerides;
- titanium dioxide;
- dextrin;
- dye carmine red-soluble red (E120).
Ka hana lāʻau lapaʻau
ʻO ka paʻakikī o losartan a me hydrochlorothiazide he waiwai hoʻohui hoʻohui antihypertensive. Ma muli o kēia, ua emi mai ka emi o ke kahe o ke koko ma mua o ka manawa e hoʻohana ai i kēlā me kēia kumuhana. ʻO ka heleʻana o kahi hopena diuretic e kōkua i:
- Hoʻoulu i ka hana o ald testosterone;
- hoʻonui hoʻonui i ka plasma retin;
- hoʻonui mahuahua o ka angiotensin II;
- hoʻemi ʻia ka nui o ka potum serum.
Ma muli o nā kiko o ka losartan, aia ka lāʻau i ka pūʻulu o ka alaiotensin 2 receptor antagonist. ʻAʻole ia e kāohi i ka kinase II (ʻo kēia enzyme ke kuleana no ka luku ʻana o ka bradykinin).
ʻAʻole hoʻokū ʻia ka lāʻau lapaʻau i ka pāpā ʻana i nā hormones a me nā kaila wai e hoʻopilikia i ka hana o ke ʻōnaehana cardiovascular.
ʻO ka mea hana he hoʻoikaika i nā hana i loko o ka ʻōnaehana koko a hiki i ka manawa hoʻokahi:
- hoʻohaʻahaʻa i ke koko a me ke kaomi ma ke kaomi pulmonary;
- ho'ēmi i ka paʻa o ka norepinephrine a me ald testosterone i loko o ke koko koko;
- hōʻemi i ka helu o OPSS;
- he hopena diuretic;
- hoʻemi ma hope o ke kaumaha;
- mea kōkua i ka hoʻonui ʻana i ka hoʻomanawanui o ka poʻe maʻi me ka hoʻomaʻamaʻa ʻana o ka puʻuwai naʻau i ka hoʻoikaika kino.
I kēia hihia, ʻaʻole ka mea o ka lāʻau i hoʻopaʻa ai i ka pani ʻia o nā hormones ʻē aʻe a me nā kaola wai e hoʻopilikia i ka hana o ke ʻōnaehana cardiovascular.
Loaʻa nā Hydrochlorothiazide i kahi mau antihypertensive a me diuretic. Hana ʻia kāna hana i ka reabsorption o nā electrolytes e loaʻa ana i loko o ka tubal distal distal. Hiki i ka hoʻonui ʻia ʻana o ka uric acid. Ma hope o ka lawelawe waha, hoʻomaka ka mea hana ma hope o 2 mau hola. Loaʻa ka hoʻokele kiʻekiʻe ma hope o 4 mau hola. Hiki ke loli ka wā i 6 a 12 mau hola.
Lapaʻau lāʻau
ʻO ka hopena antihypertensive ma hope o hoʻokahi ka wai o ka lāʻau lapaʻau i hōʻea i kona kiʻekiʻe ma hope o 6 mau hola. Ma luna o nā hola 24 e hala, ua emi iki ka hopena. ʻO ka wehe ʻana o ka plasma i ka lāʻau a me kāna metabolite he 600 ml / min a me 50 ml / min, ma kēlā.
ʻO ka huki ʻana o ka hana ikaika e hele mai ana ma o nā pūpū a me nā ʻōpū (a me ke bile).
ʻO ka huki ʻana o ka hana ikaika e hele mai ana ma o nā pūpū a me nā ʻōpū (a me ke bile).
Nā hōʻailona no ka hoʻohana ʻana
Kau ʻia ka lāʻau lapaʻau no nā maʻi penei:
- He maʻi haole. Hoʻohana ʻia ka lāʻau lapaʻau no nā kumu therapeutic a me prophylactic.
- Hypertrophy o ka ventricle hema. Hoʻomaopopo ʻia ka lāʻau lapaʻau no ka pale ʻana o nā maʻi cardiovascular.
Nā Hoʻohui
Hoʻohana nui ka hoʻohana ʻana i ka lāʻau lapaʻau me ka loaʻa ʻole o ke kauka. Nui kekahi mau contraindications:
- hypersensitivity i hoʻokahi a i ʻole he mau mea i ka hoʻonohonoho ʻana;
- mai nā keiki a hiki i ka 18 mau makahiki (ʻo ka hopena o ka hana ikaika ma ke kino o nā keiki ʻaʻole i aʻo ʻia);
- ka heleʻana o ka maʻi kalabsorption glucose-galactose, ka maʻi lactase a ʻole intolerance lactose;
- ka wā hāpai a me ka manawa o nā umauma;
- ka moʻolelo koʻikoʻi o nā maʻi pūpū, cholestasis;
- ʻO ka maʻi Addison;
- huki;
- hypotension koʻikoʻi;
- kidney pathology (inā he hana hōʻemi ma lalo iho o 30 ml / min);
- anuria
- hypokalemia refractory;
- hyperkalemia
- He paʻakikī ke kāohi mellitus.
Me ka mālama pono
Ma mua o kekahi mau maʻi i laila e pono ai no ka koho koho ʻia ʻana ma kahi maʻi. Ma ka manawa like, ʻike pinepine ʻia ke kauka no ke kūlana o ka mea maʻi. Me ka mālama akaʻa, ua kau ʻia nā papa i kēia mau hihia:
- stenosis (mitral a aortic);
- hoʻōla ʻia ma hope o ka hoʻololi ʻana i ka keiki;
- nee, he hana i ka maʻi hypertrophic cardiomyopathy;
- ka hele ʻana o ka paʻakikī o ka puʻuwai koʻikoʻi;
- hyperaldosteronism kumu mua;
- maʻi maʻi cerebrovascular;
- angioedema.
Pehea e lawe ai iā Blocktran GT
Loaʻa nā papa papa no ka hoʻokele waha. ʻAʻole hoʻopilikia ka ʻai i ka pharmacokinetics, no laila, ua hoʻopau ʻia ka lāʻau lapaʻau i kēlā me kēia manawa kūpono: ma mua o ka ʻai, i ka wā eʻai ai, a ma hope o kēlā.
Manaʻo ʻia ka laʻana maʻamau o kēlā me kēia lā he 1 papa, ka lawe ʻia hoʻokahi. Kūʻai - 1 mau manawa i kēlā me kēia lā.
I kekahi mau manawa, ʻaʻole e lawe mai kēia laula i ka hopena therapeutic i makemake ʻia, a laila, ma lalo o ke alakaʻi o ke kauka, hiki ke hoʻonui i ka maʻi i nā papa ʻelua i kēlā me kēia lā. Pono e helu ʻia kēia nui i ka 2 ana. Hoʻomaʻamaʻa pinepine, nā mea maʻi me ka haole hypertension i ke ʻano o ke ʻano o ka maʻi.
Me ka maʻi diabetes
I ka mālamaʻana i nā maʻi me ka maʻi maʻi e kiaʻi mau i ke kūlana o ka mea maʻi.
Mai ka pīhoihoi o ka naʻau a me ka ʻōpū, ua hiki ke hoʻonui ʻia.
Nā hopena ʻaoʻao o Blocktran GT
ʻO nā hopena kūpono mai ka hoʻohana ʻana i ka lāʻau lapaʻau e hiki ke hoʻopili i nā ʻōnaehana kino like ʻole. Hōʻike nā haneli i nā lā mua o ka lawe ʻana i nā papa, hoʻopau koke ʻia lākou.
ʻŌpala Gastrointestinal
ʻO ka ʻeha he mau constipation a me ke ʻeha i ka ʻōpū. Hiki i ka flatulence, waha maloʻo, gastritis, sialadenitis, pancreatitis, hyponatremia.
Hematopoietic mau hui
Mai nā pae uila a me ka lymphatic system, nānā pinepine ʻia ka anemia i nā maʻi. E hele pinepine ʻia ka Leukopenia, agranulocytosis, thrombocytopenia, a me ka purpura.
Pūnaehana pīhoihoi waena
Mai ka pūnao a me ka hoʻonaninani, hiki ke hoʻonui ʻia i ka momona, asthenia, haki, ʻeha a me nā hōʻeha.
ʻO ka hapa maʻamau, ke hiamoe nei, nā nāwaliwali, nā hopohopo, nā neuropathy peripheral, nā pilikia hoʻomanaʻo, ka nui o nā hopena, ke kaumaha, nā haunaele i ka sono, ke kani ʻana a me ka tinnitus, conjunctivitis, a me ka nalowale o ka ʻike.
I waena o nā hopena maʻamau e pili ana i ka ʻōnaehana urinary, kāhea ʻia nā maʻi ʻo ka urinary.
Mai ka pūnaehana urinary
I waena o nā hopena maʻamau e pili pono ana i ka ʻōnaehana urinary, ua kapa ʻia nā maʻi urinary tract, hōʻemi ʻia ka potency i nā kāne, hana koʻikoʻi o ka renal, a me ka helehelena o ka peremptory urination. ʻO ka Hydrochlorothiazide i kekahi mau hihia ke kumu i ka glucosuria, neʻritis interstitial.
Mai ka papa huhū
ʻO kekahi mau mea maʻi e hoʻopiʻi nei i ka ulu ʻana o ka ihu, ka pipi a me nā hōʻailona o nā maʻi e hoʻopili ai i ka ʻōpū o ka ʻaoʻao mākaukau (me ka sinusitis a me ka pharyngitis). ʻO kēlā mau hiʻohiʻona e hōʻike pinepine ʻia e ke kuni.
ʻOi aku ka maʻamau o ka rhinitis, bronchitis, pōkole o ka hanu, ka edema pulmonary, nā wahi maʻi.
Ma ka ʻāpana o ka ʻili
ʻO ka lawe ʻana i ka lāʻau lapaʻau hiki i ka lāʻau maloʻo, photosensitivity, hyperemia, ka momona nui o ke kino, ke kino necrolysis epidermal, ka ʻili o ka ʻano o ka lupus erythematosus systemic.
Mai ka ʻōnaehana musculoskeletal
Loaʻa ka hopu ʻana, nā ʻeha hope, myalgia, ʻeha ma nā wāwae a me ka umauma. Ua manaʻo ʻia ʻo Arthralgia, fibromyalgia a me ka hoʻohuihui hōʻike ʻike ʻia.
Mai ka ʻōnaehana musculoskeletal ma hope o ka lawe ʻana i ka lāʻau lapaʻau, ʻike pinepine ʻia nā hoʻopaʻapaʻa.
Mai ka pūnaehana cardiovascular
ʻO nā hopena kūpono i ka wā mālama e hiki ke:
- hoʻonui ulu naʻau;
- orthostatic hypotension;
- arrhythmia;
- angina pectoris;
- bradycardia;
- ʻōpala kūloko
- ʻeha i ka naʻau.
Allergies
Allergy he hopena hypersensitivity i kahi hapa o ka lāʻau. Ua hui pū ʻia me ka minamina, urticaria, rash, angioedema.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
I ka wā o ka mālama ʻana me ka lāʻau lapaʻau, hiki i nā mea maʻi ke loaʻa nā hopena o ka hopena e like me ka lohi, ka hoʻohaʻahaʻa ʻana i ka ʻike a me ka ʻike ʻike ʻana o ka hupa a me ka nalowale o ka ʻike. No kēia kumu, pono e mālama ʻia i ka wā e holo ai a hoʻokomo i nā haʻuki hoʻokūkū ikaika.
Nā ʻōlelo kikoʻī
Hiki i ka blocktran ke hoʻonui i ka paʻa o ka serum creatinine a me nā koko urea. Hoʻololi pinepine kēia mau loli i nā mea maʻi e loaʻa ana i ka stenosis o nā palaka a i ʻole nā aʻa.
Allergy he hopena hypersensitivity i kahi hapa o ka lāʻau.
Hoʻohana i ka wā hāpai a me ka lactation
I ka lāʻau lapaʻau, ʻaʻohe ʻikepili e pili ana i ka hopena o kēia lāʻau lapaʻau i ke olakino a me ke ʻano o ka pēpē. I kēia hihia, e pili ana ka lāʻau lapaʻau iā RAAS, ma ka mōʻī hiki ke alakaʻi i ka hoʻomohala ʻana a me ka make o ka fetal i ka wā e lawe ai i ka lāʻau lapaʻau i ka lā 2 a me 3th trimester o ka hāpai ʻana.
Inā pono e hoʻohana i ka lāʻau lapaʻau i ka mālama ʻana o nā wahine lactating, ʻōlelo mau aku nā kauka i ka hōʻoki ʻana i ka lactation, ʻo ka waiū umauma e loaʻa ka mea liʻiliʻi o ka losartan.
Wahi Hoʻohui Blocktran GT keiki
ʻAʻole ʻike nā ʻikepili e pili ana i ka hopena o ka lāʻau i ke wā kamaliʻi. No kēia kumu, ʻaʻole i kuhikuhi ʻia nā keiki i ka lāʻau lapaʻau.
Hoʻohana i ka wā kahiko
ʻO ka hopena o nā hoʻokolohua lapaʻau, ʻaʻohe pilikia inā ka lawe ʻana i kahi mana maʻamau o ka lāʻau lapaʻau. ʻAʻohe hāpai ʻia ka hoʻonui ʻana i ke ʻano.
Lā nā poʻe loea i ka hoʻohana ʻana i kēia lāʻau lapaʻau i ka wā o ka umauma.
Ke noi no ka hana renal haukapole
I kekahi mau hihia, lawe i ka lāʻau lapaʻau i hana ʻia i ka pōʻino i loko o nā keiki. ʻO kēia ka mea i wehewehe ʻia e ka pale o RAAS, e loaʻa ana ma hope o ka lawe ʻana i ka paila. Kahi ala ʻaila a paʻa me ka pau ʻana o ka lāʻau hoʻokipa.
Me ke akahele, pono ke kau i ka lāʻau i nā mea e loaʻa ana i ka stenosis arela ʻoiau.
Ke noi no ka hana lawelawe lēʻaleʻa
I ka hopena o nā noiʻi pharmacological, ua hōʻike ʻia kahi piʻi koʻikoʻi i loko o ka losartan i ke koko o nā poʻe maʻi me ka cirrhosis o ka ate. No kēia kumu, ua hōʻemi ʻia ka dosage no ka hana naʻau lēwa.
Ka helu o Blocktran GT
ʻO ka wehe ʻana i ke ʻano a i kau ʻia e ke kauka ke alakaʻi i ka overdose o ka lāʻau. Hoʻohālikelike ia me ke ʻano o ke koko haʻahaʻa, tachycardia, bradycardia. ʻO ka hydrochlorothiazide ka hopena i ka hypochloremia, hypokalemia, hyponatremia. Malia paha i hoʻonui i ka arrhythmias.
I ka hopena o nā noiʻi pharmacological, ua hōʻike ʻia kahi piʻi koʻikoʻi i loko o ka losartan i ke koko o nā poʻe maʻi me ka cirrhosis o ka ate.
Ke hoʻokuʻi i ke kūlana o ka mea maʻi, hana nā kauka i nā diuresis paʻa a hoʻokō i ka mālama maʻi. I kēia hihia, ʻaʻole maikaʻi ka hemodialysis.
Hoʻopili pū me nā lāʻau ʻē aʻe
Ua hoʻohālikelike ʻia ʻo Angiotensin II mea hoʻohālikelike i kekahi mau mea i ka hanana o ka hoʻomaʻamaʻa paʻakikī. I kēia hihia, ʻokoʻa ke ʻano o ka waiwai losartan me nā lāʻau ʻē aʻe.
- ʻAʻole i aʻo ʻia ʻo Aliskiren ma muli o ka loaʻa o ka hoʻomohala ʻana i nā mākau ma ka hana o nā keiki a me ka hypotension koʻikoʻi.
- Me nā pale o ACE. ʻO ka maʻamau pinepine kahi hiʻohiʻona o nā hana renal, syncope, hypotension koʻikoʻi a he hyperkalemia paha.
- Hoʻohana pinepine ʻia me ka sympatholytics a i ʻole nā antihypertensive e alakaʻi i ka hoʻonui like ʻana o ka hana a ka lāʻau lapaʻau.
- Me ka diuretics potassium-sparing, nui nā mea maʻi e hoʻomohala i nā kiʻekiʻe o ka potassium i loko o ke kino.
- Me ka fluconazole a me rifampicin, hōʻemi ʻia ka hopena o ka losartan.
- Me nā barbiturates a me nā analgesics narcotic. Aia ka pilikia nui o ka hypotension orthostatic.
- Me nā lāʻau lapaʻau hypoglycemic. Pono ke hoʻoponopono lōkahi, no ka mea ua hoʻemi ʻia ka maikaʻi o nā lāʻau lapaʻau.
Hoʻolaha ka waipuna
Lawe nui ʻia nā papa ʻaina e hoʻohui me ka hoʻohana ʻana i nā mea inu ʻona. Hiki i kēia mau hana ke alakaʻi i nā hopena maikaʻi loa. Hiki i ka Hydrochlorothiazide i mua o ka étanol e hiki i ke hypotension orthostatic.
Nā kuʻina
He loaʻa nā lāʻau lapaʻau kekahi mau analogues e hoʻohālikelike ʻia e nā hui Lūkini a me nā haole. I waena o lākou i nā mea maʻamau a me nā lāʻau lapaʻau me ka hopena like:
- Vazotens H;
- Lorista N;
- Gizaar Forte;
- Presartan H;
- Simartan-N;
- Gizortan.
Waihue huaʻōlelo waiho nā huaʻōlelo
Oe ke kuai i ka lāʻau lapaʻau ma ka papa lāʻau.
Hiki iaʻu ke kūʻai me ke kī ʻole
Loaʻa nā lāʻau lapaʻau mai ka pūʻulu o ka ʻāmaʻomaʻo reseptotin II receptor i loaʻa ma ka lāʻau lapaʻau.
Hoʻolaha Kūmaʻa ʻo Blocktran GT
ʻO ke kumukūʻai o ka lāʻau lapaʻau e hilinaʻi ana i ka nui o ka papa o nā papa. ʻO ke kumu hoʻohālikelike i nā lāʻau lapaʻau ma Moscow mai 220 mau rubles. mau pāleka (30 mau papa).
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Pono ka wahi e waiho ai i ka lāʻau i ka maloʻo, e pale ʻia mai ka lā pololei. He kūlana wela - ʻaʻole kiʻekiʻe ma mua o + 25 ° С.
ʻO ka lā kau
Kūpono i nā kūlana i mālama i ka lāʻau, hoʻopau ka ola o nā papa i nā mahina 24 mai ka lā o ka hoʻokuʻu. Ma hope o kēia manawa, pāpā paʻa ka lāʻau lapaʻau.
Mea hana
ʻO ka lāʻau lapaʻau e hana ʻia e Pharmstandard-Leksredstva OJSC. Aia ka hale kūʻai lāʻau lapaʻau ma Kursk ma ka helu: st. 2nd Aggregate, 1a / 18.
Hōʻike ʻo Blocktran GT
Alexander, 48 makahiki, Volgograd
Ua lawe ʻia ka lāʻau lapaʻau ma ke ʻano o ka mālama ʻana ma hope o ka loaʻa ʻana o kahi maʻi hypertensive. I ka wā mua, ua kū mai kaʻeha a me ka lohi. Kauka ke kaukaʻi ʻaʻole e hōʻole i ka loaʻa. I ka lua o ka pule, ua kū nā hopena hopena. Ua paʻa ke papa hana hoʻoponopono.
Tatyana, 39 makahiki, Khabarovsk
Ua nui wau i ka maʻi koko kiʻekiʻe no nā makahiki he nui. E hana wikiwiki ai ka lāʻau lapaʻau. Ma mua o kēlā, ua kauoha ke kauka i nā lāʻau ʻē aʻe, akā ʻaʻole lākou i lawe i kekahi hopena.
