No ka maʻi type 2, ke kauka nei ke kauka i kahi kīʻaha haʻahaʻa-kiʻekiʻe, ke aʻo ʻana i nā haʻuki kūpono, a me nā paila haʻahaʻa.
I kēia manawa, aia kahi koho nui o nā ʻōpū o ka melemele o ka hou ka wai e pono ke lawe me ka lua o nā maʻi maʻi. Loaʻa lākou a pau i ka ʻenehana o ka hana, loaʻa i kā lākou mau ʻike a me nā contraindications, nā hopena maikaʻiʻole.
Koho ʻia nā papa ʻenehana hou he nui, ʻike ʻia nā mea he nui e like me ke ʻano o ka mea maʻi, "ʻike" ʻona, he maʻi a me nā hoʻopiʻi ʻānō.
E noʻonoʻo pono ʻia ka papa ʻaina kōkōlohi i hoʻolaʻa ʻia i hoʻohana ʻia no ke ʻano lāʻau type 1 a me ke ʻano 2. E ʻike i nā lāʻau lapaʻau hou āpau i ʻoi loa ka maikaʻi, a he aha ka hoʻomohala ʻia e pili ana?
Ka papa lāʻau
Hoʻomaopopo ia e kuhikuhi i nā papa haʻahaʻa kōlala inā loaʻa i ka mea maʻi i ka nui o ke kōpaʻa i loko o ke kino, a ma ka hopena o ka maʻi maʻi ma mua.
A i ʻole ʻole e pili ana i ka hemahema o nā hualoaʻa no ka manawa lōʻihi ma hope o ke papa lāʻau therapeutic, i hōʻike ʻia ma mua.
E hoʻomanaʻo e hoʻohana ʻole ʻia kēia mau lāʻau lapaʻau e mālama ai i ka maʻi maʻi type 1, a ua ʻōlelo ʻia me ka mālama kūikawā i ka wā hāpai.
Ka helu ʻana i nā lāʻau lapaʻau no nā maʻi maʻi type 2.
- Hāʻawi ka huaʻai o ka sulfonylureas i ka hōʻemi o ka pae o ka glycogen i loko o ka ate, hāʻawi i ka hoʻonui i ka hana o ka hormone (insulin) me nā pahuhopu hou aʻe o ka hoʻihoʻi ʻana i nā cell pancreatic.
- ʻO Biguanides a me thiazolidinediones nā lāʻau lapaʻau e hoʻonui ai i ka hikiwawe o nā kopa i loko o ke kino i ka hormone, aʻo lākou e hoʻolohi ana i ka lilo ʻana o ke kō i loko o nā mea kani.
- Loaʻa i nā Meglitinides ka hoʻonui i ka hana insulin pancreatic.
- Hoʻomaopopo ʻia nā mea paʻa o ka glucosidase e hōʻemi i ka kō i loko o ke kino, hoʻonui i ka hana o ke kāwili ʻana o nā pona i ka ʻōpū, a me ka hoʻemi ʻana i ke kaupaona kino ma ka hoʻemi ʻana i ka huina o nā huamona.
I ka ʻoiaʻiʻo, ʻoi ke kaʻina o nā lāʻau lapaʻau hoʻohaʻahaʻa mai ka nui ma mua. I kēia manawa, hiki ke hoʻohui ʻia i ka papa inoa me nā lāʻau lapaʻau ʻehā mau hua - Galvus, Januvia.
Me ka hui pū ʻana o kēia mau lāʻau me nā lāʻau lapaʻau ʻē aʻe, hiki i ka hoʻonui iki ʻana i ke kao o ka glucose i ke kino.
Sulfonylureas
Ua hoʻohana ʻia nā lāʻau lapaʻau o kēia ʻano i loko o nā hana lapaʻau no ka hapalua o hoʻokahi haneli, a ʻoluʻolu hoʻi i kahi inoa maikaʻi ma muli o ko lākou hopena. Ua loaʻa iā lākou ka hopena o ka hilo i ke kō, no ka mea ke hoʻopili pololei nei lākou i nā peka pancreatic.
ʻO nā hopena biochemical e hele mai ana i ke kino o ke kanaka ka mea i ka "hoʻokuʻu" i ka insulin, ma muli o ke ʻano o ka ulu ʻana o ka hormone i ka ʻōnaehana kaila nui o kekahi kanaka.
Hoʻonui ka lāʻau lapaʻau o kēia pūʻulu i ka hikiʻole o nā palupalu palupalu i ke kō, kōkua i ka hoʻomau i ka hana piha o nā kuhi a hōʻemi i ka hopena o ka hoʻomohala ʻana i nā pathologies cardiovascular.
Eia nō naʻe, e kūlike ana i ka maikaʻi o nā pono o nā derivatives o ka sulfonylurea, hiki ke hoʻomaopopo i ka hopena maikaʻi mai kā lākou hoʻohana.
- ʻO ka waiho ʻana o nā hana beta o ka iʻa.
- Allergic mau hopena o ke kino.
- ʻO ka loaʻa kālā.
- Hōʻino iā i ka hana kaʻi ʻana o ka ʻōpuhi.
- Hoʻonuiʻia ka hopena o ka hypoglycemia.
I ka wā e mālama ai me kēia mau lāʻau, pono ka mea maʻi e hahai i ka pāʻai haʻahaʻa, a me ka hoʻopili ʻana i nā papa i ka ʻai ʻana i ka ʻai. ʻAʻole kuhikuhi ʻia nā hua o nā sulfonylureas no ka mālama ʻana i ka maʻi pancreatic, ma ka wā hāpai a me ka lactation.
ʻO nā lāʻau lapaʻau nui e hoʻohaʻahaʻa ai i ka maʻi diabetes i kēia hui:
- ʻO Maninil kahi papa papa me nā pae like ʻole o ka mea hana ikaika i ka dosage, hiki ke hānai ʻia i nā manawa a pau o ka hoʻomohala ʻana o nā pathology. Ke hoʻolako nei ka lāʻau lapaʻau i ka hōʻemi o ka honi mai 10 a 24 mau hola, ke komo.
- Hōʻike ʻia ka Glycvidone e kahi liʻiliʻi o nā contraindications, a ua noi ʻia no nā maʻi maʻi, a me ka poʻe i kōkua ʻole i ka meaʻai kūpono. Ua kau ʻia ka lāʻau lapaʻau i loko o ka hana like ʻole o ka pūmaʻomaʻo, no ka mea ʻaʻole lākou i hana i kona kāpae ʻia mai ke kino.
- ʻO Amaryl kekahi o nā lāʻau lapaʻau maikaʻi loa no ka lua o ka maʻi. ʻAʻole ia e hoʻonāukiuki i ka hoʻonui ʻana i ke kaumaha o ke kino, a ʻaʻole ia e hāʻawi i ka maikaʻi i ka ʻōnaehana cardiovascular.
- Hōʻike ka Diabeton i ka hana kiʻekiʻe ma ka mua o ka hana o ka hormone hana. A hāʻawi pū kekahi i ka mālama i nā kīʻaha koko mai nā hopena maikaʻi o ka glucose kiʻekiʻe i ke kino.
Kūloko ke kumukūʻai o nā papa Maninil mai 150 a 200 mau rubles, ke kumukūʻai ʻo Amaril 300 mau rubles no nā hapa 30, a e kūʻai ʻia ʻo Glycvidon ma kahi o 450 mau rubles. ʻO ke kumu kūʻai o Diabeton he 320 mau rubles.
Hāʻawi ʻo Meglithinide
ʻO ka hana o ke ʻano o kēia 'o nā mea lapaʻau ka mea e hoʻoulu ai i ka hana ʻana o ka hormone e nā kīlo. ʻO ka maikaʻi o ka lāʻau lapaʻau e pili koke me ka neʻe o ke kō. ʻO ke kiʻekiʻe ke kiʻekiʻe, e hana ʻia ka nui o ka hormone.
ʻO nā luna nui o kēia hui ʻo NovoNorm a me Starlix, e pili ana i nā papa o ka hanauna hou, a hōʻike ʻia e ka hopena pōkole. Pono ʻoe e lawe i ka lāʻau lapaʻau i kekahi mau minuke ma mua o ka ʻai ʻana.
Ma ke kānāwai, i ka hapa nui o nā hihia, ua hōʻike ʻia kēia mau lāʻau ma ke ʻano he nui loa o ka mālama ʻana. Loaʻa iā lākou nā hopena liʻiliʻi e like me ka ʻeha o ka ʻōpū, ke kahakaha, nā hopena maʻi.
Nā hiʻohiʻona o ka hoʻohana ʻana a me nā ʻano o ka lāʻau lapaʻau:
- Ua koho paʻa ʻia ka hewa o ka NovoNorm. Kuhi pinepine ʻia e lawe i 3 a 4 mau manawa i ka lā, ma mua o kahi pāʻina. E holo maikaʻi ana ka lāʻau lapaʻau, no laila ʻo ka hopena o kahi hāʻule iʻa i ka glucose i hōʻemi ia i ka nolino.
- ʻO ka palena ka nui o ka waiwai ikaika o Starlix i mālama ʻia i ke koko 1 hola ma hope o ka lawe ʻana i nā papa. I kēia manawa, ua hoʻomaopopo ʻia ka hopena o ka hopena o ka lāʻau i ka wana.
ʻAʻole kōkua ʻo Starlix i ka loaʻa ʻana o ka paona momona, ʻaʻole ia e hoʻopilikia i ka hana a me ke ʻano o nā pūpū, a ʻaʻole pū nō hoʻi i ke ate. ʻO ka hoʻohālikelike o nā lāʻau lapaʻau e hilinaʻi i nā hiʻohiʻona pilikino o ka mea maʻi a me kāna mōʻaukala olakino.
Kūlike ke kumukūʻai o NovoNorm mai 180 a 200 rubles, he lāʻau lapaʻau nui loa ʻo Starlix, a ma nā papa he 120 he kumukūʻai ʻo 15,000 rubles.
Hoʻohana ʻia me ka biguanides a me thiazolidinediones
ʻO nā lāʻau lapaʻau o kēia pūʻulu, inā loaʻa i nā biguanides, ʻaʻole e ʻae i ka glucose ka mea e hoʻokuʻu ʻia mai ka ate, ʻoiai e hāʻawi ana i ka hoʻemi ʻana a me ka lawe ʻana i ke kō i ka hakahaka o ka cellular a i loko o nā ʻāpana malū o ke kino kanaka.
ʻAʻole kuhikuhi ʻia kēia mau lāʻau no ka mālama ʻana i ka mellitus type type 2 i nā mea maʻi i loaʻa ka mōʻaukala o ka renal a i ʻole pohō.
Hoʻololi ka lōʻihi o ka hana o nā lāʻau lapaʻau mai 6 a 16 mau hola, a i ka manawa like ʻaʻole lākou e hāʻawi i ka loli koke ʻana o ka glucose i loko o ke kino. ʻO ka hopena maʻamau ka hopena o ka nausea, nā pilikia o ka digestive, a me nā loli i nā ʻāpana momona.
Mai ka hui o nā biguanides, nā waiʻaila e hoʻohaʻahaʻa i ka wai no ka maʻi maʻamau ʻo 2, penei ka papa inoa.
- ʻO Siofor ka lāʻau lapaʻau mua loa i hōʻike ʻia no nā mea maʻi me kekahi ʻalihi o ka momona a i ʻole ka nui kino o ke kino, no ka mea e hoʻolako ai i ka hoʻolilo ʻana. ʻO ka nui loa ka nui o ka pākahi i kēlā me kēia lā he ʻekolu mau pālaha, a pono e mahele ʻia i hoʻokahi mau pona.
- Kōkua ʻo Metformin e hoʻolohi i ka hoʻopio ʻana o ke kō i loko o ka wahī, a me ka hoʻoulu ʻana i kona hoʻohana ʻana i nā kōpili peripheral. Nā maʻi: impalired renal function, hana hoʻoponopono hou ma hope o ka ʻoihana.
Kūpaʻa ke kumukūʻai o ke kālā ma ka mea hana, ka nui o nā papa i loko o ka pānaʻi a ʻokoʻa mai 200 a 300 mau rubles.
Ke hana nei ʻo Thiazolidinediones i ke kumumanaʻo e like me nā biguanides. Akā, ʻo ka mea i hōʻike ʻia, ʻoi aku lākou iʻoi aku kaʻoi aʻe o ka uku, ʻoiai lākou he papa inoa nui o nā hopena maikaʻiʻole.
Hiki i kēia hui ke hōʻike ʻia e nā lāʻau lapaʻau i lalo mai:
- Hiki ke kuhikuhi iā Actos ma ke ʻano he monotherapy no ka mālama ʻana i kahi maʻi o ka lua. ʻO nā hemahema o ka lāʻau lapaʻau, ke piʻi nui nei ka nui o ke kino o ke kino i ka wā o kona hoʻokele ʻana.
- ʻO Avandia kahi lāʻau lapaʻau e hana ana i kāna hana e hoʻomaikaʻi i nā hana metabolic, e hoʻohaʻahaʻa ana i ke kaila o ke kō, a me ka hoʻonui ʻana i ka ʻāʻī o nā kaila o ka insulin.
I ka nui o nā hihia, ua kuhikuhi ʻia ʻo Avandia e like me ka ʻāpana o ka hui ʻana, a ʻehā hoʻi e like me ka lāʻau hoʻokahi. Hōʻai loa ia e hoʻohana i ka wā hānau keiki, i ka wā kamaliʻi, me nā pilikia me ka ʻōnaehana cardiovascular.
ʻO ka kumukūʻai kumukūʻai i nā lāʻau lapaʻau no Avandia ʻo 600-800 rubles. E kūʻai ʻia nā Actos i ka mea maʻi mai 3000 mau rubles.
Nā Kuhi Inoa o Alpha Glucosidase
Ke kōkua nei kēia mau lāʻau lapaʻau e kāpae i kahi nui o ka pūpū hāpū e hoʻohemo i nā hoʻokaʻina paʻakikī. No muli o kēia, ʻoi aku ka wikiwiki o ke kaʻina o ka hoʻopili ʻana o nā polysaccharides.
ʻO nā inhibitors o Alpha-glucosidase nā lāʻau lapaʻau hou e hōʻemi i ke kō koko, hoʻomaʻamaʻa ʻole i nā hopena maikaʻi ʻole, a ʻaʻole i hoʻonāukiuki i ka hana ʻana o ka digestive a me ka gastrointestinal tract.
Pono e lawe koke i nā papa me ka "kukahi mua o ka meaʻai." Hōʻike ka loiloi hoʻomanawanui i ka lāʻau lapaʻau e hoʻopiʻi pono me ka hana o ka hoʻohaʻahaʻa i ke kō koko koko, ʻoiai ʻaʻohe hopena i ka pancreas.
Hiki ke hoʻopōmaikaʻi ʻia nā lāʻau lapaʻau i loko o kēia ʻano me nā papaʻaila e hoʻohaʻahaʻa i ke kō, a me nā insulin. Eia naʻe, hoʻonui i ka loli o ka ulu ʻana o ka hypoglycemia.
ʻO nā mea kaulana a maikaʻi hoʻi o kēia hui.
- Hoʻomaopopo ʻia ʻo Glucobai i ka wā i poki ai ka pīpī i ke kōpono ma hope o ka ʻai ʻana. Hiki maikaʻi ʻia ka poʻe maʻi, ʻaʻole pili ia i ke kaumaha o ke kino. Hāʻawi ʻia nā pilila ma ke ʻano he hana hoʻoponopono koʻikoʻi e hoʻohui i kahi papa haʻahaʻa haʻahaʻa. ʻO ka nui loa ma kēlā me kēia lā he 300 mg, mahele ʻia i ʻekolu noi.
- ʻO Miglitol kahi lāʻau lapaʻau i kauoha ʻia no ka mālama ʻana i ke ʻano o ka maʻi type 2, i ka wā a ka meaʻai a me ka hana kino e hāʻawi aku ai i ka hopena therapeutic i makemake ʻia.
Koho ʻia ka helu o Miglitol, ma ke kānāwai, me ke ʻano o ka hoʻohana ʻana. ʻAʻole hiki ke kuhikuhi i ka manawa o ka hānau ʻana i kahi keiki, i ka wā kamaliʻi, me nā maʻi maʻi o ka ʻōpū gastrointestinal, me ka hiki ʻana i nā hernias nui.
Kūlike ke kumukūʻai o Glucobay mai 500 a 800 mau rubles, kūʻai ʻia ʻo Miglitol ma kahi o 600 rubles.
Nā lāʻau lapaʻau hou
ʻAʻole kū kū ka ʻoihana lapaʻau i kēlā me kēia makahiki, i kēlā me kēia makahiki nā lāʻau hou i synthesized no ka hakakā ʻana i ka maʻi diabetes 2 mau. ʻO ka mea i hala koke nei, ua puka ʻia nā mea i kapa ʻia ʻo dipeptidyl peptidase, nāna e kōkua i ka hoʻomaikaʻi ʻana i ka synthesis o ka insulin, akā i ka manawa like ua alakaʻi ʻia lākou e ka nui o ke kō i loko o ke koko.
I kekahi kino olakino, ʻoi aku ma mua o ka 75% o ka hormone ka mea i hana ʻia ma lalo o ke ʻano o nā hormones kikoʻī, i hui pū ʻia me ka papa o nā incretins.
Hoʻokomo ʻia ia mau mea i kahi kaʻina e kōkua ai i ka hoʻokuʻu ʻana i ka glucose mai ka paleka a me ka huki ʻana i ka hormone ma o nā puna o ke pancreas. Hiki i nā lāʻau lapaʻau hou ke lilo i monotherapy, a hiki ke hoʻokomo ʻia i ka mālama paʻakikī.
ʻO ka lāʻau lapaʻau e pono e lawe i ka wā o ka ʻai a ma hope paha. Ua hoʻomanawanui maikaʻi lākou e nā maʻi. ʻO nā ʻelele ʻauhau o kēia kulana mau papa:
- ʻO Januvia kahi lāʻau papa papa kuʻi. Lawe ʻia nā papa i hoʻokahi manawa i ka lā, ʻaʻole lākou e hoʻonāukiuki i ka hoʻonui ʻana i ke kaupaona ʻana o ke kino, e hāʻawi i ka mālama ʻana i ke kōʻai maoli ma loko o ka ʻōpū ʻole, a ma hope o ka ʻai ʻana. Hoʻomaopopo ia e pale aku i ka lāʻau i ka holomua o ka patolo, hōʻemi ka hopena o nā hoʻopiʻi.
- ʻO Galvus kahi lāʻau lapaʻau e hoʻoulu i ka hana o ka pancreas. Hōʻike ʻia ia e like me ka lāʻau monotherapeutic, hoʻohui ia i kahi meaʻai maikaʻi a me ka hana kino olakino. Hiki ke kuhikuhi ʻia i ka hui pū ʻana.
ʻO ke kumukūʻai o nā papa ovivius mai 3000 rubles, e hilinaʻi ana i ka mea hana a me ka nui o nā papa i loko o ka pākeke, māhuahua e hoʻonui ka uku. A ma Galvus ke kumukūʻai o 800-1600 rubles.
Nā pale a me ka hāpai ʻana
E like me ka hōʻike ʻana ma luna, hōʻike nui nā lāʻau lapaʻau contraindication ka manawa o ka hānau ʻana. A ʻo ka ʻoiaʻiʻo ke hiki i nā mea ikaika ke komo i ka plasenta, ma kēlā me kēia, pili i ka hoʻomohala ʻana o ka pēpē e hiki mai ana.
Inā hōʻike ka mea maʻi i ka diabetes mellitus type 2, a ua lawe ʻo ia i nā lāʻau lapaʻau hoʻolaʻa koko, a laila loaʻa ʻo ia i ke ʻano maʻi o ka insulin i ka wā hāpai. A e kūpaʻa kēia i ka hope o ka mālama mau ʻana e ke kauka hele mai, ʻāpono ʻia ke kō.
Ua kuhikuhi ʻia ka kauka e ke kauka i kahi kao ma kahi o kahi kaikamahine a i wahine paha ma mua i lawe ai i nā palaʻai e hoʻohaʻahaʻa i ke kōpī i loko o ke kino. ʻAʻole waiwai nui no ka ʻāina maʻamau ke mālama kai ʻana.
ʻO ka hoʻokō ʻana me nā ʻōlelo a pau a ke kauka e pale ai i nā hoʻopiʻi koʻikoʻi e hopena ana mai ka kiʻekiʻe o ke kō i loko o ke kino.
ʻO ke wikiō ma kēia ʻatikala e hāʻawi i kahi ʻike o ka wai kōkōlolo hoʻohuhinu i ke kō.
