Long insulins lōʻihi: inoa, kumukūʻai, nā hoʻohālike o nā lāʻau lapaʻau

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ʻO ka insulin no ka maʻi maʻi o ka ʻano o ka ʻano mua, a emi ʻole hoʻi i ka lua, he lāʻau nui ia. Ua kūleʻa i ka insulin hormone, pono e hoʻoulu ʻia e ka pancreas i kekahi nui.

Kālai pinepine, nā maʻi maʻi e kuhikuhi wale i nā mea pōkole a me ka ultrashort insulin, nā injections o nā mea i hāʻawi ʻia ma hope o kahi pāʻina. Akā aia pū kekahi he mea hana lōʻihi ka hana insulin, aia kekahi mau koi i ka manawa o ka injection.

Ma lalo e noʻonoʻo mākou i nā inoa kālepa kalepa o nā insulins me ka hana lōʻihi, ko lākou mau lāʻau lapaʻau a me nā hihia inā pono nā injections, a me ka pane a ka maʻi maʻi maʻi maʻi e hoʻohana lōʻihi.

ʻO ka insulin hana lōʻihi

Kūkulu ʻia o ka maʻi ʻano mua o nā ʻano he insulins lōʻihi e like me ka insulin basal, a i ke ʻano lua me ka mono-therapy. ʻO ka manaʻo o ka insulin basal ʻo ke ʻano he insulin, pono e hana ʻia i ke kino i ka wā o ka lā, ʻaʻohe o ka meaʻai. Akā me ke ʻano maʻi diabetes type 1, ʻaʻole nā ​​maʻi āpau i kahi maʻi pancreas e hiki ai ke hōʻea i kēia hormone like i nā dosis liʻiliʻi loa.

I kēlā me kēia ala, hoʻohui ʻia ke ʻano o ka lāʻau me ka inika pōkole a i ʻole ka pōkole o ka inanā.

Nā kuʻuna i ka wā e pono ai ke kuhikuhi i ka insulin hana lōʻihi:

  • ke hoʻokaʻawale ʻana i ke kakahiaka o ke kakahiaka;
  • ka hoʻonohonoho ʻana o ke kō koko i ke kakahiaka ma kahi ʻōpū ʻole;
  • ka mālama ʻana i ke ʻano o ka maʻi maʻi lua, e pale i kona hoʻololi ʻana i ke ʻano mua;
  • i ke ʻano mua o ka maʻi maʻi, ka ʻoki ʻana i ka ketoacidosis a me ka mālama ʻana i ka mahele o nā hanana beta.

ʻO ka insulins lōʻihi lōʻihi i hana ʻia i ka koho, ua hāʻawi ʻia nā mea maʻi me ka NPH-insulin i kapa ʻia ʻo Protofan. He wai ʻula nāu nō, a ma mua o ka hoʻonā ʻia ʻana ka lūlū e pono ai ke neʻe ai. I kēia manawa, uaʻike maopopo ke kaiāulu o nā endocrinologists i ka manaʻo he kumu maikaʻi loa ʻo Protofan ma ka pale ʻana o ka pale mai o ka pale ʻana, e hoʻoulu ai i ka hoʻoulu ʻana i nā antibodies i ka insulin.

Ke hoʻomaka nei kēia mau mea i kahi ʻano i komo ai nā antibodies insulin, e hoʻohele ʻole ai ia. Eia nō hoʻi, hiki i ka nui o nā nīnū ke hana i ka nui i ka wā ʻaʻole pono kēia. Loaʻa kēia hopena i ka hiʻohiʻona me ka līlī liʻiliʻi i loko o ke kō, ma loko o 2-3 mmol / l.

ʻAʻoleʻike kēia ka manaʻo o ka mea maʻi, akā, ma ka laulā, lilo ka kiʻi ʻōmaʻomaʻo. ʻO kēia manawa hou, ua ulu ʻia nā lāʻau lapaʻau ʻē aʻe i loaʻa ka hopena i ke kino o ka mea maʻi. Nā kuʻina

  1. Lantus;
  2. Levemir.

He ʻāpana poloka lākou, ʻaʻole pono e lulu i mua o ka paʻi ʻana. Hiki ke maʻalahi ke kūʻai aku i ka analogue lōʻihi lōʻihi i kekahi lāʻau lapaʻau.

ʻO ke kumukūʻai kūpono o Lantus i ka Lūkini Lūkini mai 3335 - 3650 mau rubles, a me Protofan - 890-970 rubles. Hōʻike nā loiloi o ka maʻi maʻi e loaʻa ka hopena o Lantus i ka kō koko koko i ke ao holoʻokoʻa.

Ma mua o ka hoʻonohonoho ʻana i ka insulin hana lōʻihi, pono ka endocrinologist e koi i ka mea maʻi e hoʻopaʻa me ka kāohi o ke kō koko, i hana ʻia mai kahi a i ʻekolu mau pule i kēlā me kēia lā. Hōʻike kēia i kahi kiʻi piha o nā hiʻi i loko o ke kō o ke koko a me ka pono o, a i ʻole ke hoʻopau ʻia o ka koho ʻana i kēia ʻano insulin.

Inā koho ke kauka i ka lāʻau lapaʻau me ka ʻole e noʻonoʻo i ke kiʻi o nā lāʻau lapaʻau o ke kōpaʻa koko, a laila ʻoi aku ka maikaʻi o ka hoʻokaʻa ʻana me kekahi endocrinologist.

Ka hana o ka hana o ka insulin lōʻihi

Hoʻohui i nā lāʻau lapaʻau lōʻihi i ka hoʻomākaukau me ka lōʻihi o ka hoʻomākaukauʻana i nā insulin. Eia hou, hoʻomaka ka hana mua i ke kino ma loko o hoʻokahi - ʻelua mau hola, hiki ke piʻi i kona kiʻekiʻe loa i ka manawa 4 - 11 mau hola, ʻo ka lōʻihi o 9 - 12 mau hola.

Hoʻopili maikaʻi ʻia nā lāʻau lapaʻau o ka wā lōʻihi, a loaʻa i kahi hopena lōʻihi. Loaʻa kēia i ka mahalo no kahi lōʻihi lōʻihi - protamine a i ʻole zinc. Hoʻokomo ʻia ka NPH-insulin i loko o kāna palapala hana protamine i loaʻa mai i ka waiū iʻa ma kahi stoichiometric ratio.

Ma ka mākeke farmacological no ka maʻi maʻi maʻi maʻi, ua hōʻike ʻia nā ʻano like insulin i nā lōʻihi manawa.

  • ʻO ke insulin engineer genetic, ke inoa kālepa Protafan XM, Humulin NPH, Biosulin, Gansulin.
  • ʻO nā insulin semi-synthetic kanaka - Humador, Biogulin.
  • Pūnaewele ʻo Pork mono - Protafan MS;
  • Insulin i ka pulu hoʻohui hoʻohui - Monotard MS.

Hoʻomaka ka lāʻau lapaʻau lōʻihi i kāna hana i loko o 1,5 mau hola ma hope o ke kau ʻana, ʻo ka nui o ka lōʻihi he 20 - 28 mau hola. Eia kekahi, ke kīhū nei nā lāʻau lapaʻau i ka insulin i ke kino o ka mea maʻi, e hoʻomaikaʻi i ke kiʻi ʻoihana maʻi a ʻaʻole hoʻonāukiuki i nā loli pinepine i ka nui o ka hoʻonāʻana i ka insulin a pōkole a pōkole.

ʻO nā lāʻau lapaʻau lōʻihi e komo i ka glargine insulin, e like me ka insulin kanaka. ʻAʻole ia he hana poʻokela nui, ʻoiai ua hoʻokuʻu ʻia i ke koko i ka manawa maʻamau mau. He koena ʻo Glargin ka pāpaona pH acid. ʻAʻohe kēia i ka hoʻopili pū ʻana me nā insulins pōkole a me ka ultrashort, no ka mea he mau pōkole pH ko kēia mau lāʻau.

ʻIke pinepine ʻia kēia mau lāʻau lapaʻau i ke kali ʻana a hoʻokele ʻia ma ka subcutaneously a i ʻole intramuscularly. Nā inoa:

  1. Insulin Glargine Lantus.
  2. Insem detemir

Aia nā ʻōmaʻomaʻo no nā injections o ka glargine o ka insulin a me ka detemir - maʻi coma maʻi, pre-coma.

Aia ma lalo iho kahi ʻōlelo kikoʻī no ka hoʻohana ʻana o Lantus insulin.

Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau

ʻO Lantus Solostar 1 ml ka mea i loaʻa i ka glargine insulin i ka nui o ka 3.63 mg, kahi kaulike e kūlike me ka 100 IU o ka insulin kanaka.

Pākoʻi pū ʻia nā poʻe punahele: glycerol, zinc chloride, sodium hydroxide, wai no ka ʻoki ʻana.

I ke nānā aku, he wai leʻaleʻa, ʻano ʻole no ka hōʻulu ʻia o ka subcutaneous i loko o ke kaila o ka pili adipose. He nui nā ʻano o ka lāʻau lapaʻau:

  • ʻO ka ʻōnaehana OpticClick, ka mea e loaʻa ai nā pahu he 3 ml. Elima mau pahu i hoʻokahi pahu.
  • 3 ml OptiSet Syringe Pen Ke pau ka insulin, pono ʻoe e kūʻai i kahi pahu hou a hoʻonohonoho i ka pahu syringe. I ka pahu pahu pahu ʻelima, ʻelima mau penikala syringe.
  • ʻO Lantus Solotar, 3 mau pahu pahu ml he mau huaʻehā. I loko o ka pahu paʻi pepa, ʻelima peni mau penikala, me nā huʻu ʻoki ʻole.

ʻO Lantus kahi lāʻau lapaʻau i ka hui o ka pharmacotherapeutic o nā lāʻau antidiabetic. ʻO ka hana ikaika o Lantus - insulin glargine he mea hoʻohālikelike o ka hana basal insulin o ke kanaka. Ua hoʻopau hoʻopau ʻia i ke kahe wai. Hoʻololi koke ka hana o ka insulin.

He hopena like ka lāʻau i ke kino o ka mea maʻi

  1. Hoʻēmi i ka glucose koko.
  2. Hoʻonui i ka uptake glucose a me ka hoʻohana ʻana e ka mākeke palupalu a me ka kiko adipose.
  3. E hoʻomoʻi i ka biotransformation o ka glucose i loko o ka glycogen i loko o ka ate.
  4. I ka wahī o ka ʻiʻo, hoʻonui i ka hana protein.
  5. Hoʻonui nā hana lipid.

Hoʻomaopopo ʻia e hana i nā inikini i hoʻokahi lā i ka lā, ʻo ka endocrinologist wale nō i ka maʻi, me ka noʻonoʻo ʻana i ka nui o nā maʻi. No nā mea maʻi me ke kō koko koko like ʻole, ʻokoʻa paha nā ʻano like, ma muli o nā hopena ʻokoʻa ma ke kino o ka mea maʻi a me kā lākou predispositions physiological.

Lantus e kuhikuhi wale no ka maʻi maʻi o ka mea mua a me ka lua, no nā pākeke a me nā keiki ma mua o ʻeono makahiki o ko lākou mau makahiki. ʻAʻole maikaʻi ʻia ka hopena o ka lāʻau lapaʻau no nā keiki ma lalo o ʻeono makahiki.

Hoʻokomo ʻia nā hopena ʻokoʻa o ka insulin i ka hihia o ke kāpena ʻana o ka nui hewahewa. ʻO nā mea nui:

  • Hypoglycemia.
  • Neuroglycopenia
  • Hoʻoponopono i nā mana Adrenergic counter.

Allergic reaksi ma ke ʻano o ka heching, puhi a me ka urticaria ma ka wahi i olana hiki ole. Hoʻohui kēia ʻōleka kūloko a hiki i ka ʻehiku mau lā a nalo iho ma luna ona.

ʻO nā ʻōlelo kikoʻī: ʻaʻole pono e kāwili ʻia ka lāʻau lapaʻau me nā ʻano ʻē aʻe o ka insulin, no ka mea he Lantus kahi ʻano pH acidic. Pono e hāʻawi ʻia nā ʻōkuhi i ka manawa like o ka lā, me ka ʻole o ka meaʻai. ʻO ke wikiō ma kēia ʻatikala e haʻi aku iā ʻoe ka mea i kuhikuhi i ka insulin.

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