ʻO kahi Galvus kahi lāʻau lapaʻau e manaʻo ʻia ana kāna hana e mālama i ka maʻi maʻi 2. ʻO ka mea hana nui a ka lāʻau lapaʻau ʻo Vildagliptin. Loaʻa kēia lāʻau lapaʻau i ke ʻano o nā papa. He hopena maikaʻi nā lāʻau lapaʻau mai nā kauka a me nā mea maʻi.
Hoʻohana ʻia ka hana o vildagliptin i ka hoʻoulu ʻana o ka pancreas, ʻo ia kona lako ʻāpana. Ke alakaʻi aku nei kēia i kahi lohi i kahi koho o ka hoʻokumu i ka enzyme dipeptidyl peptidase-4.
ʻO ka hoʻohaʻahaʻa wikiwiki ʻana i kēia enzyme e hoʻoikaika ai i ka hoʻonui ʻana i ka mea huna o kahi pona o ka glucagon e like me ka peptide a me ka glucose i hilinaʻi i ka glucose.
Nā hōʻailona no ka hoʻohana ʻana
Hoʻohana ʻia ka lāʻau lapaʻau i ka mālama ʻana i ka maʻi type 2.
- ʻoiai ka lāʻau lapaʻau wale nō i hui pū me ka meaʻai a me ke ʻano hana kino Nā hōʻike ʻana e hōʻike nei i kēlā mau hana e hāʻawi i kahi hopena mau;
- i ka hui me metformin i ka hoʻomaka ʻana o ka lāʻau lapaʻau, me ka hopena ʻole o kaʻai ʻana a me ka hoʻoikaika kino kino;
- no nā poʻe e hoʻohana i nā analogues e pili ana i ka vildagliptin a me ka metformin, no ka laʻana o Galvus Met.
- no ka hoʻopiha ikaika ʻana o ka mākaukau e pili ana vildagliptin a me ka metformin, a me ka hoʻohui ʻana i nā lāʻau me ka sulfonylureas, thiazolidinedione, a i ʻole insulin. Hoʻohana ʻia ia i nā hihia o ka mālama ʻole me ka monotherapy, a me kaʻai ʻana a me ka hana kino;
- ma ke ʻano he triple therapy i ka waiho ʻole ʻana o ka hopena o ka hoʻohana ʻana i nā lāʻau lapaʻau e pili ana i nā derivatives sulfonylurea a me ka metformin, i hoʻohana mua i ke ʻano o ka ʻai a me ka hoʻoikaika kino kūlohelohe;
- ma ke ʻano he triple therapy i ka hala ʻole ʻana o ka hopena o ka hoʻohana ʻana i nā lāʻau lapaʻau e pili ana i ka insulin a me ka metformin, i hoʻohana mua ʻia, e kau ʻia ma ka meaʻai a me ka hoʻoikaika kino kino.
Nā ʻōpala a me nā ʻano kumu o ka hoʻohana ʻana i ka lāʻau
Kahi ʻia ka hopena o kēia lāʻau lapaʻau ʻokoʻa no kēlā me kēia maʻi e pili ana i ka nui o ka maʻi a me ka hoʻomanawanui i ka lāʻau o ka lāʻau. ʻO ka hāpai ʻana o Galvus i ka lā ʻaʻole e hilinaʻi i ka kō kai. Wahi a nā loiloi, i ka wā e hana ai i kahi maʻi maʻi, ua hoʻomaopopo koke ʻia kēia lāʻau lapaʻau.
ʻO kēia lāʻau lapaʻau me monotherapy a i hui pū paha me metformin, thiazolidinedione a i ʻole insulin i lawe ʻia mai 50 a 100 mg i kēlā me kēia lā. Inā hōʻike ʻia ke ʻano o ka mea maʻi me ka ikaika a hoʻohana ʻia ka insulin e hoʻomau i ka pae o ke kō i loko o ke kino, a laila ma ka helu o kēlā me kēia lā he 100 mg.
Ke hoʻohana nei i ʻekolu mau lāʻau, no ka laʻana, vildagliptin, derivatives sulfonylurea a me ka metformin, heʻano maʻamau ka hana o kēlā me kēia lā.
Hoʻomaopopo ʻia ka nui o nā memo o ka 50 mg i ka hoʻokahi i ke kakahiaka, pono ke hoʻokaʻawale ʻia kahi hapai o 100 mg i ʻelua inikua: 50 mg i ke kakahiaka a me ka huina like o ke ahiahi. Inā no kekahi kumu i hala ka lāʻau lapaʻau, pono e lawe koke ʻia, ʻoiai ʻaʻole eʻoi aku i kēlā me kēia lā i ka lā o ka lā.
ʻO ka maʻaʻana o kēlā me kēia lā o Galvus i ka mālamaʻana i ʻelua mau mea momona a 50 paha i kēlā me kēia lā. No ka mea i hoʻohana ʻia nā lāʻau lapaʻau i loko o ka hana paʻakikī me ka Galvus e hoʻonui i kona hopena, ʻo ka nui o kēlā me kēia lā o 50 mg e pili ana i 100 mg i kēlā me kēia lā me ka monotherapy me kēia lāʻau lapaʻau.
Inā ʻaʻole i hopena ka hopena o ka mālama ʻana, e pono e hoʻonui i ka lāʻau o ka lāʻau i ka 100 mg i kēlā me kēia lā, a kuhikuhi pū nō hoʻi i ka metformin, sulfonylureas, thiazolidinedione, a i ʻole insulin.
I nā mea maʻi me nā pilikia i ka hana ʻana o nā ʻiole kūloko, e like me nā pūpū a me ka ate, ʻo ka nui loa o ke kiʻekiʻe o Galvus ʻaʻole iʻoi aku i ka 100 mg i kēlā me kēia lā. I ka hihia o nā hemahema koʻikoʻi i ka hana o nā keiki, pono ke ʻano iki o kēlā me kēia lā ʻo 50 mg.
Nā meaʻala o kēia lāʻau lapaʻau, me kahi makana no ka pae pāʻālua ATX-4: Onglisa, Januvia. ʻO nā hui nui e pili ana i ka waiwai like ʻo Galvus Met a me Vildaglipmin.
Hoʻomaopopo nā mea maʻi e pili ana i kēia mau lāʻau, me nā hōʻike pū kekahi e hōʻike i ko lākou hoʻololi i ka mālama ʻana i ka maʻi maʻi maʻi.
ʻO ka wehewehe ʻana i ka lāʻau lapaʻau Galvus Met
Lawe ʻia ʻo Galvus Met ma ke alo aku, holoi ʻia me ka wai nui. Kuhi ʻia ka lā o kēlā me kēia lā ka nui no kēlā me kēia, akā, ke hāʻawi nei ʻo ka nui loa o ka lāʻau ʻaʻole e hoʻonui i ka 100 mg.
Ma ka hoʻomaka mua ʻana, ʻo ka nui o ka lāʻau i lawe ʻia e mālama i nā kaona o ka vildagliptin i lawe ʻia mua a me / a me ke metformin. I mea e hoʻopau ai i nā hopena ʻaoʻao mai ka ʻōnaehana hoʻoili, lawe ʻia ka lāʻau me ka meaʻai.
Inā hāʻawi ka hopena me ka vildagliptin e like me ka hopena i makemake ʻia, a laila e kuhikuhi ʻia ka hana ʻo Galvus Metom. No nā mea hoʻomaka, kahi paona o 50 mg ʻelua mau manawa i kahi lā a ma hope, hiki iā ʻoe ke hoʻonui i ka dosis a hiki ke hoʻokō ʻia ka hopena.
Inā ʻaʻole maikaʻi ka mālama ʻana me ka metformin, i hilinaʻi ʻia i ka lāʻau i kau ʻia ma mua, ua noi ʻia ʻo Galvus Met e lawe ʻia i ke kao i ka metformin ma ke ʻano o ka 50 mg / 500 mg, 50 mg / 850 mg, 50 mg / 1000 mg. Pono e hoʻokaʻawale ʻia ka nui o ka lāʻau i ʻelua mau wai.
Inā ʻōlelo ʻia ka vildagliptin a me ka metformin, i kēlā me kēia ma ke ʻano o nā papa hoʻokaʻawale, a laila hiki ke kuhikuhi ʻia ʻo Galvus Met e hoʻohui iā lākou, e like me ka hoʻouka hou ʻana i ka nui o 50 mg i kēlā me kēia lā.
I ka hui pū ʻana me nā lāʻau lapaʻau e pili ana i ka deronoma o ka olonylurea a i ʻole i ka insulin, ka nui o ka lāʻau lapaʻau i helu ʻia i loko o ka papa inoa iho: 50 mg 2 mau manawa i kahi lā e like me ka analog o vildagliptin a i me ka metformin, i ka nui o ka lawe i kēia lāʻau lapaʻau.
ʻO Galvus Met he contraindicated i nā maʻi nā mea i hana ʻole i ka hana renal a i ʻole ka hopena ʻole o ka pūpū. ʻO kēia ma muli o ka loaʻaʻana o Galvus Met a me kāna mau mea ikaika mai ke kino e hoʻohana ai i nā keiki. I ka poʻe me nā makahiki, e emi iki ka hana o kēia mau mea.
ʻO ka maʻamau ka mea maʻamau o nā maʻi i ʻoi aku ma mua o 65 mau makahiki. Ua kuhikuhi ʻia nā poʻe maʻi o kēia makahiki e Galvus Met ma kahi liʻiliʻi e mālama pono ai i ke kaʻe o ka glucose koko ma ke pae maʻamau.
Hiki ke kuhikuhi ʻia ka lāʻau lapaʻau ma hope o ka hōʻoia ʻana i ka hana maʻamau o nā keiki. Pono ka nānā ʻana i nā hana luhi i ka poʻe maʻi ma mua.
Nā hopena hopena
Hiki i ka hoʻohana ʻana i nā lāʻau lapaʻau a me Galvus Met ka mea e hoʻopilikia i ka hana a nā kino o ke kino a me ke kūlana o ke kino holoʻokoʻa. ʻO nā hopena ʻokoʻa maʻamau i hōʻike ʻia:
- hoʻomāʻeha a me ke poʻo;
- kūwili lima;
- ka manaʻo ʻana o ke kolamu;
- holo pōpilikia e ukali ana;
- reflux gastroesophageal;
- ʻeha a me ka ʻehaʻeha i ka ʻōpū;
- ulia pōpilikia ʻūlū;
- nā huahuʻi, constipation a me nā maʻi;
- ka māla ʻana
- haʻahaʻa kino kino i nā maʻi a me nā hopena;
- nā hana haʻahaʻa haʻahaʻa a me ka wikiwiki wikiwiki;
- akeʻa a me ka maʻi pancreas, no ka laʻana, ka hepatitis a me ka pancreatitis;
- ʻano ikaika o ka ʻili;
- ke ʻano o nā huʻi.
Nā maʻi hoʻohālikelike i ka hoʻohana ʻia ʻana o ka lāʻau lapaʻau
ʻO nā mea kumu aʻe a me nā loiloi paha e hoʻohālike ʻia e mālama ʻia me kēia lāʻau lapaʻau.
- kahi hopena kūlohelohe a i ʻole keʻulepili pilikino i nā mea ikaika o ka lāʻau;
- maʻi pūpū, pale a me nā hana ʻole;
- nā kūlana e hiki ke hana i ka hana ʻole a like me ka lua, a me ka maʻi, ka maʻi a me ka maʻi maʻi;
- nā maʻi o ka ʻōnaehana cardiovascular, ka huhū puʻuwai, myocardial infarction;
- maʻi ʻeha;
- maʻi ketoacidosis maʻi 'ōhele ʻia e ka maʻi, kahi coma, a i kahi kūlana predomatous, me kahi hoʻopiʻi o ka maʻi diabetes. Eia kekahi ma kēia lāʻau, pono ka hoʻohana ʻana i ka insulin;
- ka hōʻiliʻili o ka waikena lactic i loko o ke kino, lactic acidosis;
- hapai a me ka umauma;
- ke ʻano mua o ka maʻi diabetes;
- ka ʻawaʻawa a i ʻole inu ʻia ka mea ʻawa;
- e hahai ana i kaʻai kīkē e pili ana i ka hana o ka calorie he nui aku ma mua o 1000 i kēlā me kēia lā;
- hoʻomanawanui. ʻAʻole makemake ʻia ke koho ʻana i nā mea lapaʻau no nā maʻi ma lalo o nā makahiki 18. Manaʻo ʻia nā poʻe ʻoi aku ma mua o 60 mau makahiki e lawe i ka lāʻau lapaʻau ma lalo o ka nānā o nā kauka;
- pau ka lāʻau i ke hala i ʻelua mau lā ma mua o nā hana hoʻokō i kuhikuhi ʻia, nā haʻawina radiographic a i ʻole ka hoʻomaka ʻana o ka hoʻohālikelike ʻana. Manaʻo ʻia ʻia e hōʻole i ka hoʻohana ʻana i ka lāʻau lapaʻau no 2 mau lā ma hope o nā kaʻina hana.
Mai ka wā e lawe ai iā Galvus a i Galvus Meta, ʻo kahi nui o nā contraindications he lactic acidosis, nā mea maʻi e hōʻeha nei i nā maʻi o ke akeʻa a me nā ʻōpio e hoʻohana i kēia mau lāʻau lapaʻau e mālama ai i ka maʻi diabetes type 2.
I loko o nā mea maʻi he 60 mau makahiki he nui ka nui o ka hopena o nā hoʻopiʻi o ka maʻi mellitus i nā manawa he nui, ka loaʻa ʻana o ka acidosis lactic e ala ʻia ka hoʻohui i ka lāʻau lapaʻau - metformin. No laila, pono e hoʻohana pono me ka makaʻala loa.
ʻO ka hoʻohana ʻana i ka lāʻau lapaʻau i ka wā o ka wā hāpai a me ka umauma
ʻAʻole i aʻo ʻia ka hopena o ka lāʻau i nā wāhine hāpai, no laila ʻaʻole ʻia ke alakaʻi ʻana no nā wahine hāpai.
I loko o nā hihia o ka hoʻonui ʻana i ke kaila o ka nui o ke kaila o nā wahine hāpai, aia nō ka loaʻa ʻana o nā mau mākaʻi congenital i loko o ke keiki, me ka loaʻa ʻana o nā maʻi like ʻole a me ka make ʻoiai paha. I nā hihia i hoʻonui ʻia i ke kō, ua ʻōlelo ʻia e hoʻohana i ka insulin e hoʻomaʻamaʻa iā ia.
Ma ke kaʻina hana e ʻike nei i ka hopena o ka lāʻau lapaʻau ma ke kino o ka wahine hāpai, kahi dosis iʻoi aku ma mua o ka 200 manawa i hoʻolilo ʻia. I kēia hihia, ʻaʻole i loaʻa kahi mea i hōʻino ʻia i ka hoʻoulu ʻia ʻana o ka pūpū a i ʻole kekahi mau hanana kōmaka. Me ka hoʻomaka ʻana o ka vildagliptin i hui pū me ka metformin ma kahi hapa o 1:10, ʻaʻole i kākau ʻia nā kue i ka hoʻomohala ʻana i ka wahine.
Eia kekahi, ʻaʻohe mau mea hilinaʻi hilinaʻi i nā mea i loaʻa i ka lāʻau i ka wā o ka hoʻoulu ʻana me ka waiū. Ma kēia mau mea, ʻaʻole i ʻōlelo ʻia nā makuahine hānai e lawe i kēia mau lāʻau.
ʻAʻole ia e hōʻike ʻia ka hopena o ka hoʻohana ʻana i ka lāʻau ma nā kānaka ma lalo o 18 makahiki. ʻAʻole ʻike ʻia nā ʻano ʻino ʻino loa mai ka hoʻohana ʻana i ka lāʻau e nā poʻe maʻi o kēia ʻano makahiki.
Lilo i ka lāʻau lapaʻau e nā mea maʻi ma mua o 60 mau makahiki
ʻO nā mea maʻi ma mua o 60 mau makahiki no ka hiki ʻana i nā hoʻopiʻi a i nā hopena paha e pili ana i ka lawe ʻana i kēia mau lāʻau, pono e kiaʻi pono i kāna hōʻeha a lawe i ka lāʻau lapaʻau ma lalo o ka mākaʻi o kahi kauka.
Nā manaʻo loea
ʻOiai ke kūpono nei kēia mau lāʻau lapaʻau e hoʻomaʻamaʻa i ke kōpaʻa i ka maʻi diabetes type 2, ʻaʻole kēia nā analog o ka insulin. Ke hoʻohana ʻia nei iā lākou, aʻo nā kauka i ka hoʻoholo pinepine ʻana i nā hana biochemical o ka ate.
ʻO kēia ma muli o ka vildagliptin, ʻo ia kahi o ka lāʻau lapaʻau, e alakaʻi ana i ka hoʻonui i ka hana o aminotransferases. ʻAʻole ʻike kēia ʻike i kekahi mau ʻōuli, akā ke alakaʻi nei i ka hōʻino ʻana o ka ate. Loaʻa kēia hiʻohiʻona i ka hapa nui o nā poʻe maʻi mai ka hui kaohi.
ʻO nā mea maʻi e lawe nei i kēia mau lāʻau lapaʻau no ka manawa lōʻihi a ʻaʻole hoʻohana i kā lākou analogues e noi ʻia e lawe i ke kaila koko ākea ma kahi o hoʻokahi makahiki. ʻO ke kumu o kēia noiʻi e maopopo ana i kekahi mau ʻahi a me nā hopena paha ma ka papa mua a me ka hoʻokomo ʻana i nā manawa kūpono e hoʻopau ai iā lākou.
Me ka pīhoihoi kūloko, ke kaumaha, ka palaualelo, ka hopena o ka lāʻau lapaʻau ma ka mea maʻi e hiki ke hoʻemi ʻia. Hoʻomaopopo nā loiloi hoʻomanawanui i nā hopena like o ka lāʻau lapaʻau e like me ka nausea a me ka maʻi maʻi. Me kēlā mau ʻōlapa, ʻōkuhi ia e pale i ka hoʻokele a i ka hana ʻana i nā hana i hoʻonui ʻia.
Nui! ʻO 48 mau hola ma mua o kekahi ʻano maʻi a me ka hoʻohana ʻana o kahi mea kū'ē, e pono ai ke kāpae i ka lawe ʻana i kēia mau lāʻau. ʻO kēia ke kumu o ka hoʻohālikelike ʻana o ka iodine, i ka pū me nā hua o ka lāʻau, hiki ke piʻi i ka maʻi kino i ka hana o ka aʻalā a me nā hana ate. E kūʻē i kēia kiʻi, hiki i ka mea maʻi ke hoʻomohala i ka acidosis lactic.
