ʻĀnō, ke koho nei i nā ala kūpono i hiki ai ke uku ʻia i ka maʻi maʻamau: eia kahi ʻenehana genetic a me nā insulins analog hou. ʻO Rinsulin wale nō ka lāʻau kūloko i hana i ka waiwai nui (ʻoi aʻe ma mua o 10%) o ka mākeke insulin ma Russia.
ʻO ka hoʻomohala ʻana o ka ʻona a me nā ʻenehana mua, ka hoʻomohala ʻana mai ka makahiki 2004, ua lawe ʻia e Geropharm. Loaʻa ka Rinsulin i nā puka 2 - Rinsulin P a me Rinsulin NPH, a ʻo ka lispro a me glargine insulin i ke ʻano o nā hoʻokolohua lapaʻau. Hōʻoia ʻia ka maikaʻi o ka waiwai e nā keʻena ʻokoʻa kūʻokoʻa ʻEulopa e hana nei. Wahi a lākou, ʻoi aku ka maikaʻi o kā mākou lāʻau lapaʻau ma mua o nā mea hoʻohui mai me nā mea like like.
Rinsulin P - wehewehe a hoʻokuʻu i nā palapala
Aia ma lalo kekahi mau ʻike e pili ana i ka lāʻau lapaʻau e hāʻawi i kahi kiʻi holoʻokoʻa o ka insulin.
ʻO ka maʻi maʻi a me nā hoʻohaʻahaʻa manaʻo e hana ia i ka wā ma mua
- Ka hana maʻamau o ke kō -95%
- Hoʻokuʻuina o ka pua thrombosis - 70%
- Hoʻopau i kahi puʻuwai ikaika -90%
- Hoʻopau i ke kiʻekiʻe o ke koko - 92%
- ʻO ka hoʻonuiʻana i ka ikehu i ka wā, hoʻomaikaʻi i ka hiamoe i ka pō -97%
Hoʻolaha
Hoʻopili koke ʻo Rinsulin P i ke koko mai ka subcutaneous tissue, e hoʻomaka ana kahi hopena hypoglycemic ma hope o ka hapalua hola. Hoʻopili ka hormone a hiki i nā ʻenehana receptor, kahi e hiki ai ke kahe aku o ka glucose mai nā kīʻaha koko i nā ʻāpana. Hiki i ko Rinsulin ke hoʻoulu i ka hana glycogen a hōʻemi i ka helu o ka synthesis o ka glucose i loko o ka ate e hoʻopili ai i ka hōʻemi glycemia.
Hoʻokū ʻia ka hopena o ka lāʻau i ka nui o ke kō, a, i ka huli ʻana, i ka mānoanoa a me ke kahe o ke koko ma ke kūloko i ka wahi i hōʻike ʻia. I ka awelika, ua like nā pharmacodynamics o Rinsulin P e like me nā insulins pōkole loa:
- hoʻomaka ka manawa 30 mau minuke
- piko - e pili ana i 2 mau hola
- ka hana nui he 5 mau hola,
- ka lōʻihi holoʻokoʻa o ka hana - a hiki i ka 8 hola.
Hiki ke wikiwiki i ka hana o ka insulin ma ke komo ʻana iā ia i loko o ka ʻōpū a i ʻole lima o luna, a hoʻoluliluli i ka ʻū ʻana ma mua o ka ʻūhā.
E uku ana no ka maʻi mellitus ma luna o Rinsulin, pono i ka mea maʻi i pili i 6 mau meaʻai i ka lā, e pono ka manawa ma waena o nā kīʻaha nui he 3 mau hola, ma waena o lākou mau kīmaha o 10-20 g o nā hāmeʻemā hoʻolāwa e koi ʻia.
Hōʻike
ʻO ka Rinsulin P hoʻokahi wale nō o nā mea kaha - nā hana like o ke kanaka. Hana ʻia ia e kahi hana recombinant, ʻo ia hoʻi, me ka hoʻohana ʻana i nā maʻi i hoʻololi ʻia genetically. Hoʻohana pinepine ʻia ʻo col col a i ʻole yeast no kēia mau kumu. I ka hoʻonohonoho ʻana a me ke ʻano, ʻaʻole ʻokoʻa ka like o kēia insulin me ka hormone o kā pancreas synthesizes.
Heʻuʻuku nā mea kōkua o ka Rinsulin P ma mua o nā mea i hoʻokomo i nā kinohi. Ma kahi o ka insulin, aia ka wai wale nō, ʻo ka metacresol preservative a me ka glycerol stabilizer. Ma ka lima hoʻokahi, ma muli o kēia, ua hoʻohaʻahaʻa ka hopena o nā maʻi kūloko ma ka wahi ʻoi. Ma kahi ʻē aʻe, ʻo ka ʻili ʻana i loko o ke koko a me ka hopena o ke koikoi o Rinsulin e ʻokoʻa iki. No laila, ke hoʻololi nei i kekahi lāʻau lapaʻau me ka waiwai ikaika no paha i hala i kekahi mau lā, i ka manawa o ka uku o ka diabetes mellitus worsens.
E hoʻokuʻu i nā palapala
ʻO Rinsulin P kahi palaile kīwaha ʻole, ʻokoʻa loa, ma ka milliliter o 100 mau ʻāpana o ka hormone.
Kuhi puka:
- ʻO nā pahu me kahi hopena o ka 10 ml, he lāʻau lapaʻau mai lākou mai e hōʻeha ʻia me ka syringe insulin.
- 3 ml mau kāleka. Hiki iā lākou ke kau ʻia i loko o kekahi peni syringe i hoʻolālā ʻia no ka pahu maʻa: HumaPen, BiomaticPen, Autopen Classic. I mea e hiki ai ke komo i ka nui o ka dosis o ka insulin, pono ke hāʻawi ʻia i ka peniʻi ma nā ʻāpana syringe me ka nui o ka nui o ka uku. No ka laʻana, HumaPen Luxura hiki iā ʻoe ke helu 0.5 i nā ʻāpana.
- Nā ʻāpana syringe penens Rinastra 3 ml. ʻAʻole hiki ke hoʻololi i nā pahu pahu i loko o ia mau mea.
Nā ʻōkuhi no ka hoʻohana iā Rinsulin
| Nā Hōʻike | Kekahi ʻano hoʻohālikelike insulin-makemake āpau. Non-insulin-hilinaʻi nonoke i ka manawa o ka aelike hypoglycemic a i ole a i ole a paleia: ketoacidosis a me na mea hou hyperglycemic kūlana, interventions opala, hapai. ʻAʻole pono e hoʻohana ʻo Rinsulin i nā pamu insulin. |
| Nā Hoʻohui | ʻO nā maʻi kūloko o kēlā me kēia a me nā ʻāpana kōkua o ka hopena. ʻAʻole ʻae ʻia ka Insulin i ka wā ma lalo o ke kō. |
| Kahi alanui hoʻokele | Hoʻohālikelike ka lōʻihi o ka hana i hōʻike ʻia i nā ʻōlelo aʻo no ka hoʻohana ʻana. I nā keʻena olakino, ʻae ʻia nā inikini intravenous a me intramuscular. >> Pehea pehea e hoʻokaumaha ʻole ai i ka insulin |
| ʻĀnō | Koho ia no kēlā me kēia maʻi maʻi maʻi kū hoʻokahi, e pili ana i nā hiʻohiʻona o ka ʻai, ka nui o ka maʻi, ka nui o ka maʻi, ka maʻi o ka maʻi maʻi. ʻO ka maʻa mau o kēlā me kēia lā o Rinsulin ma ka 0.5-1 mau waihona o ka hormone i ka kg. |
| Ka helu o nā ʻōlelo kuhikuhi | ʻĀina aʻoaʻo: Rinsulin R - ʻekolu mau manawa i ka lā, 30 mau minuke ma mua o ka papaʻai maʻamau, Rinsulin NPH - ʻelua mau manawa, ma mua o ka ʻaina kakahiaka a ma mua o ka hiamoe. |
| Nā rula hoʻomaka | Koho ʻia ka lōʻihi o ka pono ma muli o ka mānoanoa o ka momona subcutaneous. ʻOi ka liʻiliʻi, ʻoi aku ka pōkole. Hoʻolahaʻili ʻia ka hopena o ka maʻa, ma hope o ke kaʻina o ka ineka. I mea e pale aku ai i ka lipodystrophy, hoʻohana ʻia ka lāʻau i ka mahana lumi, i kēlā me kēia manawa e lawe ʻia kahi kui hou a hoʻololi ʻia ka pūnaewele injection. |
| Laki | Pono ʻo Rinsulin i kahi mālama mālama kūikawā: i ka 2-8 ° C ke kū mau nei ia no 2 mau makahiki, ma 15-25 ° C - 4 mau pule. ʻO nā hōʻailona o ka luku ka peʻe, nā flakes a me nā ʻalā i loko o ka pahu pahu. ʻAʻole hiki ke hoʻokaʻawale ʻia ka lāʻau lapaʻau i nalowale i ka helehelena i ka helehelena, no laila, me ka kānalua iki ʻole, e pono ke hoʻololi ʻia ka maikaʻi o ka pahu o Rinsulin i kahi mea hou. Luku ʻia ka Insulin e ka radiation ultraviolet, no laila mālama ʻia nā hue ma nā pahu pepa, a pani ʻia nā penikala syringe me kahi pāpale ma hope o kēlā me kēia hoʻohana. >> Pehea e mālama ai i ka insulin |
Hiki paha nā hopena i makemake ʻole ʻia
ʻO ka haʻahaʻa o nā hopena ʻokoʻa o Rinsulin he haʻahaʻa loa, ʻo ka hapa nui o nā mea maʻi e loaʻa wale ana i ka hypoglycemia mālie.
ʻO ka papa inoa o nā hopena i makemake ʻole ʻia e like me nā ʻōlelo aʻoaʻo:
- Hiki paha ke hypoglycemia inā ua hewa pono ka nui o ka nui o ka lāʻau a ua ʻoi aku ka nui o ka maʻi o ka physiological no ka hormone. ʻO ka hoʻokō ʻole ʻana i nā ʻōkuhi no ka hoʻohana ʻana hiki ke hoʻolilo i ka kahe o ke kō: ka hana ʻona (ʻaʻole i hiki i ka pūnaka) ka hōʻuluʻulu ʻana o ka pūnaewele injection (high air high, compress, friction), faulty syringe pen, hana pilikino ʻole. Pono e hoʻopau ʻia ka hypoglycemia i kona wā i ʻike ʻia ai kāna mau hōʻailona mua: malaise, pā nui, pōloli, hōʻeha. Mālama pinepine ʻia he g g ka nui o nā mea momona o 10-15 no kēia: ke kō, kōlā, nā papa ʻaila. ʻO ka hypoglycemia koʻikoʻi hiki ke alakaʻi i ka hoʻōmi ʻole ʻana i ka hoʻopili o ka nupepa, ma muli o ke koma.
- ʻO ka hopena ʻokoʻa maʻamau ka maʻi maʻamau. ʻO ka pinepine, hōʻike ʻia lākou i kahi ʻaka a i ʻole ʻulaʻula paha i ka wahi i ʻōlelo ʻia a nalowale i kekahi mau pule ma hope o ka manawa i koho ʻia ai ka maʻi insulin. Inā hele ka wā huki, hiki ke lawe i nā antihistamines. Inā ua lilo ke kaila i kahi ʻano maʻamau, i ka maʻi urticaria a i ʻole ke edema o Quincke, pono e hoʻololi ʻia Rinsulin R.
- Inā hele ka lōʻihi ma ka maʻi maʻi maʻi hyperglycemia, ua helu ʻia ka nui o ka inikua o ka insulin a no ka emi ʻana o ke kō o ke koko ma mua o hoʻokahi mahina. Me kahi hoʻoliʻekuʻe nui i ka glucose i ka maʻamau, hiki i kahi hōʻemi i ka manawa maʻamau i ka maikaʻi.
Hoʻokomo i kekahi mau mea kūpono i ka hana o ka insulin, no laila nā mea maʻi me ka maʻi maʻi i ka maʻi insulin e hoʻonohonoho pono me ke kauka i nā lāʻau āpau, nā hōʻola kanaka a me nā mea hoʻolako i ka meaʻai a lākou e hoʻolālā ai e hoʻohana.
Paipai ʻia ke aʻo e mālama pono i nā pūʻulu o nā lāʻau lapaʻau e hiki mai ana.
- nā lāʻau lapaʻau hormonal: contraceptives, hormone thyroid, glucocorticosteroids;
- nā hopena no ka hypertension: diuretics of the thiazide subgroup, nā lāʻau āpau e pau i -pril a me -sartan, lazartan;
- waiora B3;
- hoʻomākaukau ka lithium;
- pilikipuna;
- kekahi mau puʻuwai hypoglycemic;
- acetylsalicylic acid;
- kekahi mau antidepresants.
Ka uku o ka maʻi mellitus maʻi a me nā mea āpau a me nā mea inu nona ka waiʻona e hiki ke piʻi i ka hypoglycemia koʻikoʻi - e nānā i ke ʻano o ka decompensated diabetes i alakaʻi. ʻO nā lāʻau Beta-blocker i hoʻohana ʻia no nā maʻi naʻau e hōʻoluʻolu i nā hōʻailona o ka hypoglycemia a pale i ka ʻike ʻole ʻana i ka manawa.
Nā hiʻohiʻona noi
Ma hope o ka pau ʻana o ka hana, luku ʻia ka insulin i loko o ka aʻai a me nā ʻōpū. Inā loaʻa i kahi maʻi maʻi ka maʻi o kekahi o kēia mau mea, pono ke hoʻoponopono ʻia ka nui o ka make o Rinsulin. Ke nānā ʻia nei ka hoʻonui nui ʻana o ka insulin i nā manawa o nā loli o ka hormonal, me nā maʻi maʻi maʻi, ka laʻala, ka trauma, ke kaumaha, nā hana hōʻeha. ʻAʻole hewa paha ka make o ka lāʻau inā he maʻi maʻi maʻi maʻi a kaʻi ka mea maʻi, huʻi, a me ka ʻaihue i ka hana ʻana o ka ʻōpū.
ʻO nā analogues kaulana loa o Rinsulin R ʻo ka Danish Actrapid a me nā American Humulin Regular. Hōʻike nā hōʻike noiʻi ʻana i ka hōʻailona o ka pono o Rinsulin ma ka pae o nā kūlana kiʻekiʻe o ʻEulopa.
ʻAʻole like ka manaʻo o ka loiloi maʻi maʻi. ^ E Ha yM. Nui, i ka huli ʻana mai kahi mea halihali i lawe ʻia i kekahi kanaka home, ʻike i ka pono o ke loli i ka dosage, ka peke i ke kō, a me ke kiʻekiʻe o ka hana. Aia nā loiloi maikaʻi aʻe o ka rinsulin ma waena o nā poʻe maʻi e hoʻohana nei i ka insulin no ka manawa mua. Loaʻa lākou i ka uku uku no ka maʻi diabetes a pale i ka hypoglycemia koʻikoʻi.
Inā hele mai kahi māla e hoʻomau, e haʻalele ʻo Rinsulin. ʻO ka maʻamau, ʻo nā insulins kanaka ʻē aʻe i hoʻokau i ka hopena like, no laila ua hoʻohana lākou i ka ultrashort ka manaʻo - Humalog a i ʻole NovoRapid.
ʻO ke kumu kūʻai o Rinsulin P - mai i ka 400 rubles. pouia i 1150 no 5 mau syringe pens.
Nā ʻokoʻa ma waena o Rinsulin P a me NPH
ʻO Rinsulin NPH kahi lāʻau lapaʻau hana maʻalahi o ka mea hana. Wahi a nā ʻōkuhi, ua hana ia i ka hoʻāla ʻana i ke kō. He kumu like like ʻo Rinsulin NPH o ka hana, hoʻokuʻu i nā mea like, nā hoʻohālike like, nā contraindications a me nā hopena ʻaoʻao e like me Rinsulin R. Ma ke ʻano he alapine, ua hui pū ʻia nā ʻano like ʻole o ka insulin - ua puʻupuʻu a me ke ʻano. Inā mālama ʻia ka hūnā ʻia o kou pono iho i ke ʻano (type 2 a me ke ʻano maʻi gestational), hiki iā ʻoe ke hoʻohana i ka lāʻau hoʻokahi wale nō.
Nā hiʻohiʻona o Rinsulin NPH:
| He manawa hana | ʻO ka hoʻomaka ka 1,5 mau hola, ʻo ka pihi he 4-12 mau hola, ʻoi aku ka lōʻihi o 24 mau hola, e pili ana i ka ʻimi. |
| Hōʻike | Hoʻopili i nā insulin kanaka, loaʻa i ka lāʻau lapaʻau ka protamine sulfate. ʻO kēia hui hui kapa ʻia ʻo is-insulin. Hāʻawi ia iā ʻoe e hoʻolōʻihi i ka lilo o ka hormone a hoʻonui i kona lōʻihi. |
| ʻO ka hiʻohiʻona o ka hoʻonā | ʻO ka Rinsulin NPH he sediment ma lalo, no laila e hoʻopili ʻia ma mua o ka hoʻokele ʻana: ʻōwili i ka pahu kaʻa ma waena o nā pāwili a huli i ia mau manawa. ʻO ka pahuli hoʻonā ke ʻano he ʻula keʻokeʻo keʻokeʻo me ka loaʻa ʻole o ka pau ʻole. Inā ʻaʻole i maloʻo ka lulu, e noho mau nā clots i loko o ka pahu, pono e hoʻololi ʻia ka insulin me ka hou. |
| Kahi alanui hoʻokele | ʻAʻohe waleutanʻo wale nō. ʻAʻole hiki ke hiki ke hoʻohana e hoʻopau i ka hyperglycemia. |
ʻO ke kumukūʻai o ka hue Rinsulin NPH ~ 400 mau rubles., ʻElima mau pahu ʻaka ~ 1000 rubles., ʻElima mau penikala ~ 1200 mau rubles.
