ʻO nā contraindications, nā hopena ʻaoʻao a me nā loiloi koʻikoʻi no ka hoʻohana ʻana iā Fraxiparin

ʻO nā pilikia me ka hoʻopili koko, nā maʻi hoʻopiʻi thromboembolic he maʻi koʻikoʻi nā maʻi nui e pono ai ka mālama koke.

ʻO nā pinepine pinepine i nā hihia, kuhikuhi nā kauka i ka lāʻau Fraxiparin. Loaʻa nā hopena ʻaoʻao a me nā contraindications no kāna hoʻohana, a he mea nui e ʻike e pili ana iā lākou.

ʻO kēia mau pilikia, aʻo ka ʻike e pili ana i ka hoʻohana ʻana i ka lāʻau, kona hopena a me nā loiloi e kūkākūkā ma hope aʻe.

Ka hana lāʻau lapaʻau

ʻO Fraxiparin ka haʻahaʻa heparin haʻalulu haʻahaʻa, ʻo ka hana i lawe ʻia i loko o ke kaʻina o ka depolymerization. ʻO kahi hiʻohiʻona hiʻohiʻona o ka lāʻau e haʻi i ka hana me ka mahalo i ka hoʻopākaʻi ʻana i ke kumu Xa, a me nā hana haʻahaʻa o Pa.

ʻOi aku ka maikaʻi o ka hana anti-Xa ma mua o ka hopena o ka aihue ma ka manawa partial thrombotic plate time. Hōʻike kēia i ka hana antithrombotic.

Ke loaʻa nei kēia lāʻau lapaʻau i nā hopena anti-inflammatory a immunosuppressive. Eia kekahi, hiki ke ʻike wikiwiki ʻia ka hana a ka luna mea, a hiki lōʻihi loa ia. I loko o nā hola 3-4, e hoʻopili maikaʻi ʻia ka lāʻau lapaʻau. Hoʻopili ʻia ia me ka urine ma o nā keiki.

Nā hōʻailona no ka hoʻohana ʻana

Hoʻohana nui loa iā Fraxiparin i kēia mau pilikia:

• ka mālama ʻana i ka infarction myocardial;
• ka pale ʻana o nā hoʻopiʻi thromboembolic, no ka laʻana, ma hope o ka hoʻomaʻemaʻe ʻana, a me ka ʻole e hana;
• prophylaxis coagulation i ka wā o ka hemodialysis;
• ka mālama ʻana i nā hoʻopiʻi thromboembolic;
• ka mālama ʻana o ka pectoris angststable.

E hoʻokuʻu i ke ʻano, ka hoʻonohonoho ʻana

ʻO ka hoʻokuʻu i ka Fraxiparin i ke ʻano o ka hopena no ka hoʻonāukiuki ʻia, i waiho ʻia i loko o kahi syringe. Loaʻa ka syringe pono i kahi palaha, i hoʻopili ʻia i 2 a 10 paha mau ʻāpana i loko o ka pahu pepa.

Kūkulu ʻia ke ʻano mea waiwai i kapa ʻia ʻo calcium adroparin 5700-9500 IU. ʻO nā mea kōkua i eia eia: calcium hydroxide, wai maʻemaʻe, a me ka acid chloric.

Nā hopena hopena

E like me ka hapa nui o nā lāʻau lapaʻau, ʻo Fraxiparin i kekahi manawa ke hopena o ka hopena.

• thrombocytopenia;
• nā maʻi kūlohelohe (maʻa mau mai ka ʻeha ʻeha ʻo Fraxiparin), me ka edema Quincke;
• ka hookahe ana o na wahi like ole;
• ʻili kino;
• ʻike maoli;
• eosinophilia ma hope o ka haʻalele ʻana i ka lāʻau;
• hōʻano hou iā hyperkalemia;
• ke ʻano o ka hematoma liʻiliʻi ma ka pūnaewele injection, ʻike hou ʻia nā bruises mai Fraxiparin (kiʻi ma lalo);
• ka hoʻonui ʻana i nā ʻike o ka hoʻomehana hepatic.

Ua ʻike ʻia kekahi mau maʻi e hoʻohana iā Fraxiparin i kahi ʻāʻī wela koʻikoʻi ma hope o kahi maʻi maʻi.

Nā Hoʻohui

Nā Fraxiparin kakau ʻōlelo iā:

• thrombocytopenia;
• makahiki a hiki i ke 18 mau makahiki;
• nā maʻi pilikino o nā kino me ka makemake i ke koko;
• hoʻolilo kikilaʻi;
• ka hopena o nā mea iʻoi aku ma o ka maʻamau;
• ʻeha a hōʻeha ʻole i nā maka, ka lolo a me ka spinal cord;
• ka huhū a he pilikia koʻikoʻi paha i kona neʻe ʻana i ka heʻe ʻana o ka hemostasis;
• pilikia hālepa hopena i hopena mai ka myocardial infarction, unstable angina, mālama ʻana i ka thromboembolism.

Me ka hoʻonui nui o ke kahe, e lawe ʻia ʻo Fraxiparin me ka makaʻala. Eia nā ʻano:

• pūpū hema;
• nā pilikia helehelena i ka retina a me ka choroid;
• hoʻomohala hana lōʻihi ma mua o ka mea i hōʻike ʻia aʻe;
• kaupaona o ke kino a hiki i 40 kg;
• ka manawa ma hope o nā hana ma nā maka, nā mākio spinal, noʻonoʻo;
• hypertension koʻikoʻi;
• kūlike ʻole me nā kūlana hana;
• ʻāhā peptic;
• lawe i nā lāʻau lapaʻau i ka manawa like hiki ke loaʻa i ke koko.

Nā ʻōkuhi no ka hoʻohana

Hoʻokomo ʻia ka Fraxiparin i loko o ka ʻōpū ma ka kiko subutanutan. Pono ka mālama ʻia o ka paʻu i nā manawa a pau e lawelawe ʻia ana ka hoʻonā.

Pono ka hoʻomanawanui. He mea nui ia e pili pono ana ka nira, ʻaʻole ma ke kihi.

Ma ka ʻoihana nui no ka pale ʻana i nā hoʻopiʻi thromboembolic, e mālama ʻia ana ka hoʻonā i loko o kahi waihona o 0.3 ml i hoʻokahi lā i ka lā. Lawe ʻia ka lāʻau no ka liʻiliʻi ma kahi hebedoma a hiki i ka wā i waiho ʻia ai ka hopena o ka pilikia.

Hoʻoponopono ʻia ka lāʻau mua ma mua o nā hana ma 2-4 mau hola. Ma ka hihia o ka orthopedic surgery, mālama ʻia ka lāʻau i nā hola 12 ma mua o ka hana a me 12 mau hola ma hope o kona hōʻea ʻana. ʻOi aku, lawe ʻia ka lāʻau lapaʻau ma nā liʻiliʻi he 10 a hiki i ka hopena o ka manawa pilikia.

Hoʻomaopopo ʻia ka dosage no ka pale ʻana ma muli o ke kaumaha o ke kino o ka mea maʻi:

• 40-55 kg - hoʻokahi manawa no ka 0.5 ml;
• 60-70 kg - hoʻokahi lā no 0.6 ml;
• 70-80 kg - ʻelua mau manawa i ka lā, 0.7 ml kēlā me kēia;
• 85-100 kg - ʻelua mau manawa i kahi lā no 0.8 ml.

No ka mālamaʻana i nā hoʻopiʻi thromboembolic, mālama ʻia ka lāʻau lapaʻau ma waena o 12 mau hola ʻelua i ka lā no 10 mau lā.

I ka mālamaʻana i nā hoʻopiʻi thromboembolic, ʻo ka paona o ke kanaka e hana i ka hana e hoʻoholo ai i ka ʻōpū:

• a i ka 50 kg - 0.4 mg;
• 50-59 kg - 0,5 mg;
• 60-69 kg - 0.6 mg;
• 70-79 kg - 0.7 mg;
• 80-89 kg - 0.8 mg;
• 90-99 kg - 0,9 mg.

I ka pale ʻana o ka ʻaila koko, pono e hoʻokaʻawale ʻia ke ʻano ma luna o nā ʻano loea o ka dialysis. ʻO ka maʻamau, ʻo ka wā e pale ʻia ai ka coagulation, ʻo ka wahi e hōʻemi ai i ka hoʻomaka mua loa o 0.3 mg no nā poʻe a hiki i ka 50 kg, 0.4 mg a 60 kg, 0.6 mg ma mua o 70 kg.

Hoʻolakoʻi ka mālama ʻia o ka infarction myocardial a me ka angina paʻa i ka hui pū ʻana me Aspirin no 6 lā. I ka mua, ua hoʻopaʻa ʻia ka lāʻau i loko o ka catheter venous. ʻO ka lāʻau i hoʻohana ʻia ʻo 86 ME anti-Xa / kg. ʻO ka manawa hou, ke mālama ʻia nei ka hoʻonā ʻālepana i ʻelua mau manawa i ka lā hoʻokahi.

Ke keu

I kahi hihia o kēlā lāʻau lapaʻau, ʻike ʻia ke koko o ke ʻano like ʻole. Inā he mea liʻiliʻiʻole lākou, a laila mai hopohopo. I kēia kūlana, pono ʻoe e hōʻemi i ka dosage, a i ʻole e hoʻonui ai i ka manawa ma waena o nā inikini. Inā nui ka nui o ke koko, a laila pono ʻoe e lawe i ka protamine sulfate, 0.6 mg kahi hiki iā ia ke hoʻohālikelike i ka 0.1 mg o Fraxiparin.

Hoʻohui nūhou

ʻO ka lawe ʻana i nā franksiparin i ka manawa like me kekahi mau lāʻau lapaʻau hiki ke alakaʻi i hyperkalemia.

Hoʻopili kēia i nā: paʻakai potasi, nā ACE inhibitors, heparins, NSAIDs, diuretics potassium-sparing, Trimethoprim, angiotensin II receptor blockers, Tacrolimus, Cyclosporin.

ʻO nā lāʻau hōʻeha e pili ana i ka hemostasis (kūlue i ka anticoagulants, acetylsalicylic acid, nā NSAIDs, fibrinolytics, dextran), me ka hoʻohana ʻana o kēia ʻāpana, hoʻonui i ka hopena o kēlā me kēia.

Hiki ke piʻi aʻe ka hopena o ke kaila inā he Abciximab, Beraprost, Iloprost, Eptifibatide, Tirofiban, Ticlopedin e lawe pū ʻia. Hiki i ka acetylsalicylic acid ke hana i kēia, akā aia wale nō i nā inikena antiplatelet, ʻo ia ka 50-300 mg.

Pono ka hoʻokaʻawale ʻana o Fraxiparin i ka wā e loaʻa ai ka poʻe maʻi i ka dextrans, nā kūlohelohe anticoagulants, a me nā corticosteroids systemic. I ka lawe ʻana o nā anticoagulants kūlike me kēia lāʻau lapaʻau, hoʻomau ʻia kona hoʻohana a hiki i ke ʻano o ka hōʻike INR.

Hoike Mai

E like me nā lāʻau'ē aʻe he nui, aia nā loiloi e pili ana no ka Fraxiparin. Aia nā mea āna i kōkua ai, a ua manaʻo ʻia ʻo ia he mau mea kūpono loa, akā ʻaʻole nā ​​mea i ʻoki ʻia nā mea maʻi e manaʻo nei he maikaʻi ʻole.

Hōʻike nā loiloi maikaʻi i ka loaʻa ʻana o ka nui o nā hopena o ka ʻaoʻao, contraindications. I ka manawa like, ʻoiai me nā ʻōlelo luhi i ka lawe ʻana i ka lāʻau lapaʻau i nā wahine hāpai, ʻaʻohe hopena i ke olakino a me ke kūkulu ʻana o ke keiki.

Nā wikiō pili

Pehea e hoʻokomo ai iā Fraxiparin:

No laila, ua hoʻākāka pinepine ʻia ʻo Fraxiparin no nā pilikia o ka hoʻopili ʻana i ke koko, ka pono no ka mālama ʻana a i ʻole pale ʻana i nā hoʻopiʻi thromboembolic. ʻO ka mea nui, ʻo ka hoʻokō pono i nā ʻōlelo aʻoaʻo o kekahi loea e hiki ke hoʻoholo i ka kūpono o kona hoʻohana a me ke ʻano kūpono. Inā ʻaʻole, i kekahi o ka loaʻa ʻole o ka hopena, hiki i kahi hopena maikaʻi ke pili me ka overdose, ka ulu ʻana o ke koko, a me ka hyperkalemia.