ʻO ka poʻe i hoʻopili ʻia i nā inikini insulin ua lōʻihi ka manaʻo e puka koke mai nā peni insulin. Ua hana nā ʻepekema mai Australia, India, Russia, Israel a me Denemaka i kēia pilikia no nā makahiki he mau makahiki.
ʻAʻole e hana koke nā hana o ke alakaʻi ʻana i nā ʻepekema honua i kēia kahua.
ʻO ka mea kokoke loa i ka hana nui o ka insulin tablet i hele mai i nā mea hoʻomohala o India a me Russia.
Ke hana nei i kaormormorm
ʻEkolu mauʻano hoʻohālikelike o ka manuahi manu monomer
Ua pau nā noiʻi e nā ʻepekema Lūkini me ka hōʻike ʻana o ka hoʻomākaukau piha ʻana i ka insulin me ka inoa mua "Ransulin", kahi ia e hana nei i ka hoʻāʻo hou.
ʻO kahi haki o kēia wahi ʻo ka hana ʻana i nā kapuwai ʻokoʻa ʻole e nā ʻepekema ʻAmelika ma ke Kulanui o Kaleponi. Hoʻohālikelike lākou i kahi pālule kupaianaha me kahi pale pale, pale i nā manaʻo i nā hopena o nā wai kūmole a lawe mālie iā ia i loko o kahi ʻāpana liʻiliʻi.
Holo i loko o nā capsule he mau mucoadhesive kūikawā (polymers kūikawā hiki ke hoʻopaʻa i kekahi mea) "" pā "ʻūlū ʻia i ka insulin.
ʻO ka mea polimika mai kahi o ka lālani i hana ai ka hiki ke pili i ka paia o ka ʻōpū.
Hoʻopaʻa ʻia i ka paia o ka ʻōpū, pale iā ia i ka insulin mai nā pōʻino o nā hopena o nā huina o ka ʻaoʻao hoʻokahi, a hoʻihoʻi ʻia ka hormone ʻē aʻe mai kēlā ʻaoʻao mai ke kahawai.
ʻO ke kumu o ka hana
ʻO ka insulin ka hormone e hua ai ka pancreas. Ma o ke kahe koko, e hōʻea i nā ʻili a me nā ʻāpana a hoʻopaʻa i ka komo ʻana o nā hāmeʻe i loko o lākou.
I ka hoʻohālikelike ʻana o ka metabolic, ʻaʻole lawa ka nui o ka ʻauhau i kēia mau kumu. Aia ka maʻi maʻi. Aia kahi pono no ka inika insulin.
ʻO ke ala e ʻoi loa a hōʻoiaʻiʻo ʻia ka mālama ʻana i ke kō o ke koko ka hoʻomaka ʻana o kekahi, i koho ʻia no kēlā me kēia mea maʻi, ʻoi ʻia ka nui o ka hormone.
Kuhi ʻia nā mea maʻi i ka lāʻau lapaʻau i kekahi mau manawa i ka lā me kahi syringe kūikawā. ʻAʻole ia he mea kupanaha ko lākou moe a pau i ka manawa i hiki ai ke loaʻa i ka lāʻau lapaʻau.
Me he mea lā e kāohi i ka waihona ma ke ʻano papa - a ua hoʻopau ʻia ka pilikia. Akā ʻaʻole maʻalahi. ʻIke ka ʻōpū i ka insulin a me ke ʻano maʻamau ʻoi pono ke eli.
Ua ʻimi ikaika nā ʻepekema ʻepekema i kahi nīnau i ka nīnau - hiki anei i hiki ke hana ʻia ka huehue o loko.
Ua hana ʻia ka noiʻi i kekahi mau manawa.
ʻO ka mea mua, pono e ʻimi i kahi kinipona ʻaʻole e makaʻu i ka wai kūlana.
Hoʻoholo mākou e waiho i ka insulin i loko o ka mea i kapa ʻia ʻo liposome. He kapoma momona kēia i hana ʻia mai nā membranes e pale aku ai i ka hopena o nā waikawa o ka ʻōpū.
ʻO kekahi mea ʻē aʻe o kahi papa o nā molekala polyelectrolyte i lilo i ka pale antienzyme. Ua kapa ʻia ʻo ia he "ʻāpana". Pono ʻo ia e ʻuwī, a paʻa ka lāʻau. Akā ʻaʻole i ʻike ʻia ka maʻa. Ua nui ka hana a me ka manawa e hoʻokō ai i kahi hopena maikaʻi.
Ua noi aku nā kānaka ʻepekema Lūkini i kahi hydrogel no kēia mau kumu. Ua hoʻohui ʻia kekahi polysaccharide, ke kumu o ka hoʻoulu ʻana i ka hana o nā mea ʻona e kū ana ma nā paia o ka pūpū liʻiliʻi. Ua mālama ʻia kahi lāʻau lapaʻau ma loko o ka hydrogel i hui pū ʻole ʻia me ka polysaccharide.
ʻO ka hana nanocoating o nā microparticles o ka insulin a i ka insulin a me ka chitosan i nā polysaccharide nanoengineered nanoengineered.
Ua hoʻohana ʻia ka momona folik (huaʻai B9) ma ke ʻano he polysaccharide, kahi waiwai i ʻike ʻia e ke pio koke i loko o kahi ʻāpana liʻiliʻi. He waiwai nui kēia waiwai ma aneʻi.
ʻO nā koena a pau o nā gels a me nā polymers i hele mālie mai ka hopena me nā huahana decay. A ua hoʻokomo maikaʻi ʻia ka insulin i loko o ke koko. Noho mau ia no ke helu ʻana a me ka helu ʻana i ka pele i makemake ʻia.
Ua hoʻokolohua ʻia e hoʻonui ʻia ka ʻike ʻana o ka insulin i nā papa.
ʻO ka maikaʻi o ka lāʻau lapaʻau i nā papa
Loaʻa ka pono o ka lawe ʻana i ka lāʻau lapaʻau.
Huhu nā poʻe maʻi i nā ʻōlelo mau ʻana.
ʻO ka hopena hōʻeha ʻole o ka lāʻau i nā papa e hāʻawi:
- kāohi i nā kīʻaha mau me nā syringes;
- ka mālama ʻole ʻana i nā pono ponoʻī
- nele i kahi kaʻina hana no ka koho ʻana i ka pūnaewele wae kūpono;
- ka hoʻopau ʻana o ka hoihoi nui i ka wā e hoʻolauna ana i ka pono ma kahi kihi.
Hiki iā ʻoe ke kanu i kahi papa i ka manawa kūpono a ma nā wahi āpau. ʻAʻole pono e nānā i nā lumi kūikawā. Hiki iā ʻoe ke mālama a lawe pū me ʻoe ʻole kahi hana hou. E maʻalahi ke kiʻi i kahi keiki e ale i kahi paʻi ma mua o ka hōʻeha ʻole ʻana me nā hōʻeha.
Ma nā hoʻokolohua hoʻokolohua, ua ʻike ʻia: ʻo ka nui o ka nui o nā papa i kūpono no ka mea maʻi, pono e hoʻonui ʻia e pili ana iā 4 mau manawa. Eia nō hoʻi ua nānā ʻia i ke kaʻina waha o ka insulin no ka manawa lōʻihi ke kākoʻo i kahi hopena hypoglycemic.
E hauʻoli ka hakahaka o ka honua holoʻokoʻa e hoʻololi i ka insulin i nā papa. ʻAʻole nō i hoʻolaha ʻia i loko o nā hana lehulehu, ʻaʻohe inoa. Aneane hiki ʻole ke kiʻi i ka hoʻomākaukau ʻana i ka insulin i nā papa - ʻoi aku ka kiʻekiʻe o kā lākou kumukūʻai.
Akā ua manaʻo ka manaʻolana e hōʻemi i nā injections hōʻeha.
