Ua kuhikuhi ʻia ʻo Atorvastatin a i ʻole Simvastatin e hoʻohaʻahaʻa i ka cholesterol a hoʻomaikaʻi i nā hana metabolic. Ua hoʻohana like nā lāʻau ʻelua no ka hoʻomaʻamaʻi ʻana, no laila, ua hōʻoiaʻiʻo lākou iā lākou iho no ke mālama ʻana a no ka pale ʻana o nā maʻi cardiovascular.
Hoʻohanohano Atorvastatin
ʻO Atorvastatin e pili ana i nā lāʻau lapaʻau lipid-hamina mai ka pae o statins. Atorvastatin calcium trihydrate (10.84 mg) kahi mea ikaika e hana i ka synthesis o kolamu. Hāʻawi kēia waiwai i ka hoʻohaʻahaʻa ʻana i ka nui o nā lipoproteins low density (LDL) a me ka density kiʻekiʻe (HDL), a laila e pale ai i ka hoʻokumu ʻana o nā kolamu pololi.
Ua kuhikuhi ʻia ʻo Atorvastatin a i ʻole Simvastatin e hoʻohaʻahaʻa i ka cholesterol a hoʻomaikaʻi i nā hana metabolic.
Ma hope o ka nānā ʻana, ua komo ka papa i ka ʻōpū liʻiliʻi, kahi e komo koke ai i ka ʻōnaehana ʻōnaehana ma o kona pā. ʻO ka bioavailability o ka mea hana ikaika he 60%. Mālama kekahi wahi o ka enzyatic i ke ʻano o ka lāʻau lapaʻau, a hoʻihoʻi ʻia nā koena mai ke kino me ka feces, ka urine a me ka humu.
Ka hānai o ke kolamu ma ka atherosclerosis, ke kaomi o nā poli i loko o nā capillaries nui a liʻiliʻi, nā hōʻailona nui no ka hoʻohana ʻana i Atorvastatin. Noi ʻia nō hoʻi ke kuhikuhi i ka lāʻau lapaʻau no ka pale ʻana i kēia mau maʻi:
- diabetes type 2;
- puʻuwai puʻuwai;
- he poho;
- haʻi maʻi
- angina pectoris;
- ischemia o ka puʻuwai.
ʻO Atorvastatin e pili ana i nā lāʻau lapaʻau lipid-hamina mai ka pae o statins.
Loaʻa i hiki i Atorvastatin ke hōʻuluʻulu i loko o ke kino me ka hoʻohana mau ʻana a me kekahi mau pathologies, no ka laʻana, inā he kīpona a pōpō paha ka lolo. I kēia hihia, ua nānā ʻia ka hopena o ka hopena o ka lāʻau. Hiki i ka mea maʻi ke hoʻopiʻi i ke maʻi, ke poʻo, ka nawaliwali ākea, a me ka hana wikiwiki. Inā ʻae ʻoe i kēia mau ʻōuli a pau, a laila ke kiʻekiʻe ka hopena o ka laʻala o ke kino.
Nā hiʻohiʻona o ka simvastatin
No ka lāʻau ʻo Simvastatin no ka pūʻulu o nā statins. ʻO ka hana ikaika o ka lāʻau ka simvastatin. Hoʻokomo nā mea hoihoi:
- titanium dioxide;
- lactose;
- povidone;
- citric acid;
- ascorbic acid;
- magnesium stearate, etc.
He kiʻekiʻe ke kūpaʻa o Simvastatin. Loaʻa ka lōʻihi o ke koina o ka waiwai ikaika i ke koko ma kahi o 1-1,5 mau hola ma hope o ka hoʻokele ʻana. Ma hope o nā hola 12, ua hoʻemi ʻia kēia kiʻekiʻe ma 90%. ʻO ke ala nui o ka excretion ma waena o nā ʻōpū, ma o nā keiki, ma o 10-15% o ka hana ikaika i excreted.
ʻO ke kumu nui o ka lāʻau lapaʻau e hoʻohaʻahaʻa i ka cholesterol i loko o nā maʻi cardiovascular. Hoʻoikaika ʻia ka lāʻau lapaʻau i loko o ia mau hihia:
- kiʻekiʻe ka piʻiʻana o ka atherosclerosis;
- ʻO ka hypercholesterolemia mua (ʻano II a me II b);
- hypercholesterolemia a me hypertriglyceridemia;
- no ka pale ʻana i ka hala ʻana o myocardial infarction, stroke, ischemic attack, atherosclerosis of the heart vessel.
ʻO ke kumu nui o ka hoʻohana ʻana iā Simvastatin he hoʻohaʻahaʻa i ka cholesterol i loko o nā maʻi maʻi cardiovascular.
Hoʻohālikelike o Atorvastatin a me Simvastatin
Kūkākūkā i kahi lāʻau lapaʻau a koho i ke hoʻoponopono ʻia dosage ka mea nui wale nō ka mea e mālama i ka manawa ʻaʻole o ka maʻi wale nō, akā ke ʻano ponoʻī o ke kino.
Hoʻohālike
ʻO nā lāʻau ʻelua e hoʻohana pū ʻia i ka cardiology no ka mālama ʻana a me ka pale ʻana i nā maʻi a me ka vascular.
ʻO Atorvastatin a me Simvastatin nā lāʻau lapaʻau maikaʻi a loaʻa hoʻokahi pahuhopu - e hoʻohaʻahaʻa ana i ke kolamu koko.
Hoʻohui pū ʻia nō hoʻi lākou e kēia mau hiʻohiʻona:
- ʻO nā lāʻau lapaʻau ke ʻano o nā ʻano wai like ʻole, akā aia ka lactose i nā mea ʻelua. No laila, pono e hoʻokaʻawale ʻia lākou me ka ʻike ʻana i kēia māhele kōkua.
- ʻO ka hopena hopena i ke ʻano o ka dizziness ka mea e hōʻike ai i nā lāʻau ʻelua. No kēia kumu, i ka wā o ka mālama ʻana, pono ʻoe e hōʻole i ka lele i kahi kaʻa a hana pū me nā hana kūpono.
- Hoʻopilikiaʻia ka lāʻau lapaʻau me nā lipid-hoʻohiolo ʻana i nā lāʻau, no ka mea e hoʻomohala ai myopathy. Inā, e kū'ē i ke ʻano o ke aʻoaʻo me ka Atorvastatin a i Simvastatin, kū mai ke mahana a me ka ʻeha o ka naʻau, a laila e haʻalele ʻia ka lāʻau lapaʻau, e hoʻololi iā lākou me nā analogues.
- ʻO ka ʻōpū a me ka lactation kahi hui hou ʻē aʻe. Pono nā wahine i ka wā hana e hoʻohana ai i ka contraception.
- Me ka hoʻohana lōʻihi a me ka overdose, ʻoi ka nui o ka hopena o nā ʻaoʻao. I ia mau pilikia, e ʻoi aku ana ka nui o ka pūpū a me ka ate. No laila, pāpā paʻa loa ʻia i ka nui o ke ʻano i kau ʻia e ke kauka.
ʻOkoʻa ka ʻokoʻa
ʻO ka mea nui ka hoʻohālikelike o ka mākaukau ʻana o ka mākaukau me ka like ʻole o ka hana ikaika. No laila, ʻo ka atorvastatin e pili ana i ka statins statins, aia ka lōʻihi o ka hopena therapeutic. ʻO Simvastatin kahi statin kūlohelohe me kahi hopena pōkole.
ʻO ka mea ikaika o Atorvastatin ka mea ikaika aku, no laila, ua loaʻa kēia lāʻau lapaʻau i nā contraindications. E pili ana kēia:
- hapai a lactation;
- makahiki a hiki i 10 mau makahiki;
- lāleʻa hemahema;
- hoʻonui nui o transaminases i ke koko;
- kahi maʻi kūlohelohe i ka lactose;
- maʻi maʻi lēpa
ʻAʻole ʻōlelo ʻo Simvastatin i hoʻohana no ka hoʻohana ʻana i nā hihia i lalo aʻe:
- hypersensitivity i nā māhele o ka lāʻau lapaʻau;
- maʻi ate
- makahiki liʻiliʻi;
- hapai a lactation;
- hōʻoki ʻia e ka ʻāʻī.
ʻAʻole pono ke hoʻohana pū ʻia ʻo Atorvastatin i nā manawa like me nā loea antibacterial a me antimicrobial. ʻAʻole hiki ke hoʻohui pū ʻia ka Simvastatin me nā proteamine inhibitor a me nā anticoagulants. Mai ʻai i ka ʻōpala ʻai a inu ʻole i ka wai ʻona i ka wā e mālama ai me nā papa. hiki i kēia hui ke hiki ke keu i ka kahe ʻana o ka hana ikaika ma ke koko.
Hiki i nā hopena ʻokoʻa ke hoʻoiho iā Simvastatin:
- pilikia hāwili;
- ʻōpala
- poʻomanaʻo
- ka hōʻino ʻana i ka hoʻāʻo a me ka ʻike (jarang);
- hoʻonui ka ESR, kahi hoʻemi i loko o nā platelets a me nā ʻoka koko ʻulaʻula.
I ka wā maʻi me ka Atorvastatin, hiki i nā mea maʻi ke ʻike i ka tinnitus, nā pilikia hoʻomanaʻo, a me kahi manaʻo o ka mau ʻana o ka mauʻu.
E kūʻē i ke kua mua o ka lawe ʻana iā Simvastatin, hiki i nā poʻo ke hōʻeha.
Hōʻike ʻia ka Hemodialysis i nā hihia o kahi overdose o simvastatin. A he mea waiwai ʻole kēia hana i ka wā like me Atorvastatin.
ʻOi ka uku
Kūʻai ke kumukūʻai o nā lāʻau lapaʻau ma ka ʻāina o ka hana a me ka dosage.
ʻO Simvastatin i hua ʻia i nā ʻāina he nui, ʻo ia hoʻi ʻo Russia, Farani, Serbia, Hungary a me ka Czech Republic. ʻO ke kumu kūʻai o kahi pākahi o 30 mau papa o 20 mg e 50-100 mau rubles. ʻO ke kumukūʻai no ka ʻaʻa i kahi lāʻau lapaʻau.
Hiki ke kūʻai ʻia ʻo Atorvastatin o ka hana Lūkini ma nā lāʻau lapaʻau ma kēia kumukūʻai.
- 110 ka ʻōpala - 30 pcs. 10 mg pākahi;
- 190 ʻōpala - 30 pcs. 20 mg pākahi;
- 610 rub - 90 pcs. 20 mg i kēlā me kēia.
ʻO kahi maikaʻi loa - atorvastatin a simvastatin
ʻO ka kauka hele wale nō e hiki ke haʻi aku i ka lāʻau a ka maikaʻi ma hope o ka hoʻopaʻa ʻana i ka mea maʻi, akā aia kekahi mau mea nui o nā lāʻau lapaʻau.
- Hiki ke loaʻa kahi hopena kūpono kūpono me ka Atorvastatin, ʻo loaʻa ia i kahi mea ikaika me kahi hopena ikaika loa.
- Hoʻokomo ʻo Simvastatin i nā hopena liʻiliʻi liʻiliʻi, ʻo ia ka mea o ka pono o kēia lāʻau lapaʻau. I ka wā e hoʻohana pololei ai, ʻaʻole e hōʻiliʻili nā mea make i loko o ke kino.
- I ka hopena o nā noiʻi maʻi lapaʻau o nā lāʻau lapaʻau, ua hōʻoia ʻia e hoʻohemo nui ʻia ʻo Simvastatin i ka kolesteroli hōʻino ʻia ma 25%, a me Atorvastatin - e 50%.
No laila, no ka lōʻihi o ka mālamaʻana i nā pathologies, pono ʻo Atorvastatin, a no ka pale ʻana i nā maʻi vascular, ʻoi aku ka maikaʻi o ka hoʻohana ʻana iā Simvastatin.
Nā Hōʻike Hoʻomaʻi
Olga, 37 makahiki, ʻo Veliky Novgorod
Ma hope o ka hōʻeha ʻana o ka puʻuwai, ua kauoha ʻia ʻo Simvastatin e hoʻohaʻahaʻa i ka cholesterol. Ua mau ke mālama iā 4 mau mahina a i kēia manawa ʻaʻohe hopena o nā hopena. ʻO ka mea hiki ʻole ke hoʻowahāwahā ʻia, ʻo ia ke kumukūʻai, ka liʻiliʻi - ka hana haʻahaʻa. Hōʻike pinepine ʻia ka hōʻike ʻana o ke kiʻekiʻe o ka kolamu a maikaʻi. Ua huhū ʻo Papa, no ka mea ua manaʻo nui ʻo ia no ka lāʻau. Ke manaʻoʻiʻo nei wau e kōkua ana ka simvastatin i nā hihia haʻahaʻa, ʻaʻole hoʻi i mua. I kēia manawa ua mālama ʻia mākou me kekahi mea ʻē aʻe.
Maria Vasilievna, 57 makahiki, Murmansk
I ka hoʻokolokolo hou, ʻōlelo ke kauka i ka hoʻonui ʻia ʻana o ka cholesterol a ʻōlelo i nā statins e lawe. Lawe wau iā Simvastatin, hahai i kahi papaʻai a hoʻopili ʻia i ka hana pilikino pono ʻole. Ma hope o 2 mau mahina i lilo ai au i kahi loiloi lua, kahi i hoʻi hou ʻia ai nā hōʻailona āpau. ʻAʻole wau e minamina i ka inu ʻana i ka lāʻau lapaʻau, ʻoiai he nui ka mea e hoʻomaopopo i ka pōʻino a me ka lapuwale i koʻu ʻano koko. Ke hauʻoli nei au ua hoʻokō ʻia ka hopena. Ke manaʻo nei wau!
ʻO Galina, 50 makahiki, ʻo Moscow
Ua makaʻu wau i ka lohe ʻana mai ke kauka ua ʻoi aku ma mua o 8. Nā manaʻo i manaʻo lōʻihi e paʻakikī ka lōʻihi. Ua kuhikuhi ʻia ʻo Atorvastatin. ʻAʻole wau i pani i kekahi mau manaolana o ka lāʻau lapaʻau, akā me ka makehewa. Ma hope o 2 mau maʻi o ka lapaʻau, hāʻule ka cholesterol i 6. ʻAʻole wau i manaʻo i ka lāʻau lapaʻau e kōkua. Makemake wau e ʻike inā ua inu paʻa wau ma ka noi o ke kauka a ʻaʻohe hopena ʻē aʻe.
ʻO nā lāʻau ʻelua e hoʻohana pū ʻia i ka cardiology no ka mālama ʻana a me ka pale ʻana i nā maʻi a me ka vascular.
Hōʻike nā kauka e pili ana i nā kauka e pili ana i Atorvastatin a me Simvastatin
ʻO Egor Alexandrovich, 44 makahiki, Moscow
ʻAʻole paʻa wau iā Simvastatin, no ka mea Manaʻo wau ia he lāʻau lapaʻau o ka makahiki i hala. I kēia manawa he mau statins hou i ʻoi aku ka maikaʻi a me ka palekana. ʻO ka hiʻohiʻona, atorvastatin. ʻAʻole hiki i kēia lāʻau lapaʻau ke hoʻohaʻahaʻa i ka pae o ka cholesterol maikaʻi ʻole, akā e hōʻemi ana i ka hopena o ka hoʻoulu ʻana o ka naʻau a me ka puʻupuʻu. ʻO ke ʻano kūpono o ka hoʻokuʻu.
Lyubov Alekseevna, 50 makahiki, Khabarovsk
Ma ke kauka lapaʻau, hoʻāʻo wau e kuhikuhi i Atorvastatin i nā mea maʻi inā ʻaʻohe contraindications. Ke manaʻoʻiʻo nei au e hana mālie nei kēia lāʻau lapaʻau, me ka hoʻoluhi ʻole i ka hana o nā wahī a me nā ʻōnaehana kino. Hoʻopiʻi pinepine nā mea maʻi i nā hopena pili, he mea nui ia. Ma hope o nā mea āpau, ʻo ka hapanui o nā penikala ke hele mai me kahi pilikia like ʻole, ka poʻe i loaʻa nā maʻi maʻi.
