ʻO Clopidogrel-Teva kahi lāʻau lapaʻau e kāpae i ka hōʻuluʻulu ʻana o ka platelet a hoʻomoʻa i nā moku coronary. Hoʻohana ʻia ka mea hana no ka mālama ʻana a me ka pale ʻana i nā pathologies cardiovascular.
Inoa Kūʻai ʻole honua
INN - Clopidogrel.
ʻO Clopidogrel-Teva kahi lāʻau lapaʻau e kāpae i ka hōʻuluʻulu ʻana o ka platelet a hoʻomoʻa i nā moku coronary.
ATX
Manaʻo ATX: B01AC04.
E hoʻokuʻu i nā palapala a me ka ʻano
ʻO ka lāʻau lapaʻau ke ʻano ma nā papa elongated o kahi kala ʻulaʻula māmā. ʻO ka mea hana e pili ana i ka clopidogrel hydrosulfate (ma ka nui o 75 mg).
Nā mea hoʻoweliweli:
- lactose monohala;
- mikulamulamina selulose;
- huki maʻi;
- crospovidone;
- hydrogenated aila ʻaila o kaʻu I;
- sodium lauryl sulfate.
Nā ʻāpana ʻāpana o nā kiʻi ʻoniʻoni penei:
- lactose monohala;
- hypromellose 15 cP;
- titanium dioxide;
- macrogol;
- ʻulaʻula a me ka melemele (ʻaila hao);
- indigo carmine.
Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa.
Ka hana lāʻau lapaʻau
ʻO ka mea ikaika o ka lāʻau lapaʻau e hōʻemi i ka hoʻohui platelet. Nā ADP nucleotides (adenosine diphosphates) pili i ka hoʻoulu houʻana i ka mea paʻa glycoprotein a hoʻopaʻa pū i nā platelets. Ma lalo o ka hopena o clopidogrel, ua hoʻohuli ʻia kēia mau kaʻina a no laila e hōʻemi ʻia ka hui platelet (hui pū). ʻAʻole hoʻololi ka hana (PDE) o ka phosphodiesterase i ka hana.
ʻO ka hopena antiplatelet o ka lāʻau lapaʻau ka lōʻihi o ke alahou o ke ola o nā platelets (ma kahi o 7 mau lā).
Lapaʻau lāʻau
Ke lawe ʻia ma ka ʻōlelo maʻamau, e hoʻopili koke ʻia nā papa i loko o ka digestive tract. Loaʻa i ka Clopidogrel kahi bioavailability kiʻekiʻe, akā i loli ʻole ia he mea pono ʻole (ʻo ia hoʻi kahi huao hua) Aia i ke koko no kahi pōkole a hoʻāla koke ia i loko o ke akea me ka hoʻolālā ʻana o nā metabolites ikaika a me ka hana. A laila hoʻopili nā clopidogrel a me ka metabolite ikaika e pili loa i nā protein koko.
I hoʻokahi hola ma hope o ka lawe ʻana i ka lāʻau lapaʻau i loko o ke koko, ʻike ʻia ka nui o ka metabolite kūlohelohe o ka clopidogrel i loko o ka plasma, kahi huaʻai o ka waikawa carboxylic.
Kuhi ʻia ka lāʻau i loko o ka kuki a me nā feces i loko o 5 mau lā. Hoʻokomo ʻia ka metabolite hoʻoikaika i loko o 16 mau hola.
Nā hōʻailona no ka hoʻohana ʻana
Ua kuhikuhi ʻia ka lāʻau lapaʻau no ka pale ʻana o nā hoʻopiʻi cardiovascular ma nā hopena aʻe:
- Myocardial infarction.
- ʻEha puhipī Ischemic.
- Ka maʻi coronary e pili ana i ka piʻi ʻole o ka mahele ST.
- ʻO thrombosis (i hoʻohana pū me ka acetylsalicylic acid).
- Hōʻaloʻolelo.
- Hoʻopili ʻo Atrial.
- I mua o nā contraindications no ka hoʻohana ʻana i nā anticoagulants o nā hana ʻole.
Nā Hoʻohui
Lā ʻia nā papa e lawe i nā mea maʻi me ka nele o ka ate (ma ke ʻano koʻikoʻi), ka hypersensitivity i ka lāʻau lapaʻau a i ʻole ke koko hoʻowalewale.
ʻO nā hoʻohalike nā hapai hoʻi, lactation a me nā keiki ma lalo o nā makahiki 18.
Me ka mālama pono
Me ka makaʻala, ʻōlelo ʻia ka lāʻau lapaʻau no ka hana ʻana i ka maʻi hakahaka (insufficiency me ka hōʻoki ʻana me ka creatinine clearance o 5-15 ml / min), hoʻonui nui ʻia (hematuria, menorrhagia), me ke ʻano ʻana o ka hōʻoki ʻana, nā hōʻeha a me nā hemahema o ka ʻōnaehana hemostatic.
I ka hoʻomaʻamaʻa ʻana o nā mea maʻi me nā maʻi pāpaʻi, hana pinepine ʻia kahi coagulogram a nānā ʻia ka hana ʻana o ke ate.
Me ka mālama aka, ua kuhikuhi ʻia ka lāʻau lapaʻau no ka hana renal impaired.
Pehea e lawe ai i ka clopidogrel-teva?
ʻO nā mea maʻi i loaʻa i ka infarction myocardial e kuhikuhi ʻia he 75 mg o ka lāʻau (1 papa) i kēlā me kēia lā no 7-35. Ma hope o kahi hahau, lawe ʻia ka lāʻau lapaʻau i loko o ka papa like like, akā ke hoʻomau ʻia ke papa lāʻau lapaʻau a hiki i nā mahina ʻeono.
ʻO nā mea maʻi me ka maʻi coronary syndrome me ka piʻi ʻole o ka mahele o ka ST kahi e mālama ʻia ai ʻo 300 mg i kēlā me kēia lā ma ke ʻano he dosis mua. A laila e hōʻemi ʻia ka nui o ka make ma 75 mg i kēlā me kēia lā, akā e hui pū ʻia ka hui ʻana o antiplatelet me ka acetylsalicylic acid. Hoʻolaha ʻia ka Therapy no 1 makahiki.
Me ka maʻi diabetes
I ka poʻe maʻi me ka maʻi mellitus, ʻike pinepine ʻia ka platelet aggregation. No ka pale ʻana i ka maʻi coronary a me ka maʻi coronary, 75 mg o clopidogrel-Teva i ʻōlelo ʻia i kēlā me kēia lā.
Pono ka lōʻihi o ka hoʻokele ʻana a me ka ʻokoʻa o nā Insulin e ke kauka, e pili ana i ke ʻano o ka mea maʻi.
Nā ʻāpana ʻaoʻao o ka clopidogrel-Teva
Ma ka ʻāpana o nā lālā o ka hihiʻo
Ma ke ʻano o ka lawe ʻana i ka lāʻau lapaʻau, hiki i ka hemorrhages ocular (retinal a me conjunctival) hiki mai paha.
Mai ka musculoskeletal a me ka hoʻopili pili
Loaʻa kekahi hopena maikaʻi aʻe ma ka musculoskeletal system. Hiki i ka ʻeha, ka arthralgia a me myalgia.
Hiki i ka lāʻau lapaʻau ke alakaʻi i ke kūkuluʻana o colitis.
ʻŌpala Gastrointestinal
Hōʻike ʻia ka hopena ma ka gastrointestinal tract e like me kēia:
- ʻeha ka ʻōpū;
- kahe ʻana o ka hoʻowalewale ʻana;
- ninaki a me ka luaʻi
- nā ninia
- nā leʻaleʻa maʻi;
- gastritis;
- lāʻau lāʻau;
- hepatitis;
- lōkohu
- stomatitis
- pūpū hema.
Hematopoietic mau hui
Mai ka ʻaoʻao mai o kēia ʻōnaehana:
- thrombocytopenia;
- leukocytopenia;
- eosinophilia.
Pūnaehana pīhoihoi waena
ʻAʻole pili ka lāʻau lapaʻau i ka ʻōnaehana piopio. Ma nā hanana pinepine, nā hōʻeha, nā hōʻeha, a me ka hilahila.
Mai ka pūnaehana urinary
Nā hopena hopena mai nā ʻāpana o ka urinary:
- hematuria;
- glomerulonephritis;
- hoʻonui i hana i loko o ke koko.
Mai ka papa huhū
Nā hopena i ka ʻōnaehana hanu:
- nā ʻoliʻoli;
- hemorrhage pulmonary;
- bronchospasm;
- pyronitis interstitial.
Mai ka pūnaehana genitourinary
ʻAʻole paʻa nā hopena.
Mai ka pūnaehana cardiovascular
Mai ka ʻōnaehana kikoo nānā i ʻike ʻia:
- kahe koko
- hypotension arterial;
- vasculitis.
Allergies
Hiki i kēia ʻano mea pili ʻia:
- ʻO ka makeʻe o Quincke;
- maʻi Serum;
- urticaria;
- huu
E pale aku i ke ʻano o ka lawe ʻana i ka lāʻau lapaʻau, hiki i kahi hopena alerine ke hiki.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
ʻIke kekahi mau maʻi i ka hōʻeha a me ka dizziness i ka wā e lawe ai i ka Clopidogrel-Teva. Pono e mālama ʻia ka nānā ʻana i ka wā e kāohi ana i nā mīkini a i ʻole e hana i nā hana e koi ana i ka pīhoihoi kiʻekiʻe.
Nā ʻōlelo kikoʻī
Ma mua o ka wehe ʻana, pono e hoʻoneʻe i ka lāʻau (5-7 mau lā ma mua o ka hōʻino) ma muli o ke koʻikoʻi o ke kahe.
Hoʻohana i ka wā kahiko
Hoʻohana ʻia ka lāʻau lapaʻau e mālama i nā mea maʻi maʻi. Akā i kēia hihia, lawe ʻia ke ala ʻole me kahi ukana hāmeʻa (hoʻokahi hāmeʻa e like me 300 mg) ma ka hoʻomaka ʻana o ka hopena.
Kuhi ʻana ʻo Clopidogrel-Teva no nā keiki
Kuʻi ʻia ka lāʻau lapaʻau no nā keiki ma lalo o 18 makahiki o kona makahiki.
Hoʻohana i ka wā hāpai a me ka lactation
ʻO ke ʻae a me ka umauma o nā maʻi nā contraindications i ka hoʻohana ʻana o kēia lāʻau lapaʻau.
ʻAʻole hiki iā ʻoe ke hoʻohana i ka lāʻau lapaʻau i ka wā hāpai.
Hoʻohana no ka hana lawelawe lēwa
ʻO nā mea maʻi me nā pathologies ate (cirrhosis, hōʻoki i ka noke) ua kauoha ʻia i ka lāʻau lapaʻau me ka mālama. I mea e pale aku ai i ka hemorrhage, pono e mālama ʻia ka mālama ʻana i ka hana o nā ate.
Clopidogrel-Teva Overdose
Me ka mālama waha hoʻokahi o nā wai nui o ka lāʻau (a hiki i ka 1050 mg), ʻaʻohe hopena koʻikoʻi no ke kino.
ʻO ka hoʻohana lōʻihi loa i nā puʻupuʻu nui e alakaʻi i ke koko.
Hoʻopili pū me nā lāʻau ʻē aʻe
Ma muli o ke kīnā o ke kahe, e pāpā i ka lāʻau e hui pū me nā lāʻau like ʻole e like me:
- Anticoagulants.
- Nā mea paʻa o Glycoprotein IIa / IIIb.
- Nā NSAID.
Pono e hoʻohui pū me ka heparin.
Pono e hoʻohui ʻia ka pale a me ka thrombolytics a me ka heparin. Me ka hoʻohana like pū me ka omeprazole, esomeprazole a me nā mea pale aku proton pump, kahi hoʻoemi o ka hopena antiplatelet.
Hoʻolaha ka waipuna
ʻAʻole hōʻike ʻia ka lāʻau e hoʻohui pū me ka hoʻohana ʻana i nā mea inu ʻawa. Hiki i ka hoʻonāukiuki ke ʻano o ke kino, i hōʻike ʻia e ka hāwau, ke nānā ʻana, ka hoʻāhewa, ka maʻi, ka ʻōpū o ka ea a me ka palpitations.
Nā kuʻina
ʻO nā lāʻau lapaʻau kaulana me nā hopena like:
- Lopirel.
- Plavix.
- Sylt.
- ʻAgrlelo Plagril.
- Aggregal.
- Egithromb.
ʻO ka hana ikaika o kēia mau analog kime a clopidogrel.
Waihue huaʻōlelo waiho nā huaʻōlelo
Hiki iaʻu ke kūʻai me ka loaʻa ʻole o ka hōʻailona?
Wahi a nā ʻōlelo kuhikuhi, e kau ʻia ka lāʻau lapaʻau i ka lāʻau lapaʻau.
Clopidogrel-Teva kumu
ʻO ke kumu kūʻai o kahi pā hale he 14 mau papa mai 290 a 340 mau rubles, 28 papa - 600-700 rubles.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Pono e mālama i kahi mālama i loko o kahi wahi pouli ma kahi mahana ʻaʻole iʻoi aku o + 25 ° C.
ʻO ka lā kau
Pono kūpono ka lāʻau lapaʻau no 2 mau makahiki.
Mea hana
Mea hana - Teva (Israel).
Hoʻokuʻu ʻia ka lāʻau lapaʻau e ka lāʻau lapaʻau.
Nā Hōʻikeʻike o clopidogrel-Teva
Irina, 42 makahiki, Moscow.
I koʻu lawe ʻana i ke ʻano koko, loaʻa iaʻu kahi kiʻekiʻe nui o nā platelets. Ua kuhikuhi aku ke kauka i ke clopidogrel. Lawe au i ka lāʻau lapaʻau no 3 hebedoma, a hoʻi hou ka helu platelet i ke koko.
Alexander, 56 makahiki, Izhevsk.
Hoʻomaka wau e lawe i kēia lāʻau lapaʻau ma ke kauoha ʻana o kekahi kauka ma hope o kahi kūhai. Ua lawe wau iā ia i 2 mau mahina a ʻaʻole wau e hoʻopiʻi nei no koʻu ola maikaʻi. ʻAʻole i hopena ʻokoʻa. ʻO ke kumukūʻai ka uku kālā.
Leonid, 63 makahiki, Volgograd.
Ua hoʻohana au i kēia mau peni no ka pale ʻana i nā hoʻopiʻi ma hope o ka pau ʻana o nā hana spinal. I ka wā hana, ua kōkua ke lāʻau lapaʻau i ka pale ʻana i nā māka koko. Ua ʻae maikaʻi ʻole wau i kona komo ʻana; ʻaʻole au i ʻike i kekahi mau hana maikaʻi ʻole.
