ʻO nā lāʻau lapaʻau Rosuvastin a me Atorvastatin he mau mea āpau hypolipidemic. Hoʻopili i nā mea hiki ke hoʻohaʻahaʻa i ka kolamu koko, loaʻa lākou nā mea antioxidant a me ka hoʻokaʻawale i ka ulu a me ka hoʻokaʻawale i nā cell tumor. Hoʻopuka ʻia e nā ʻano lāʻau lapaʻau Lūkini a ʻo ia i waena o nā lāʻau lapaʻau.
Nā hiʻohiʻona o rosuvastatin
ʻO ka lāʻau lapaʻau he papa biconvex keʻokeʻo e loaʻa ana i nā mea kaha rosuvastatin, i loko o nā kaʻe aʻe nei:
- 5 mg;
- 10 mg;
- 20 mg;
- 40 mg
ʻO nā lāʻau lapaʻau Rosuvastin a me Atorvastatin haʻahaʻa haʻahaʻa koko, loaʻa nā mea antioxidant a pale i ka ulu ʻana o nā cell tumor.
Hoʻololi ʻia nā papa i nā pahu. ʻO ka nui loa i nā helu he 7 pcs., ʻO ke kaulike he 300 mau ʻō.
ʻO ka bioavailability o ka lāʻau e pili ana i ka 20%. ʻO ka pae kiʻekiʻe loa o ke koko a hiki i ka hola 5 ma hope o ka hoʻokele ʻana. ʻO ka pau hoʻopau hapa-ola he 19 mau hola.
ʻO ka ʻōmato i ʻōlelo ʻia i ka lāʻau, ʻo 10 mg (no nā poʻe maʻi o ka lāhui Mongoloid - 5 mg), i lawe ʻia i hoʻokahi lā. Inā pono, hiki ke hoʻonui ʻia i 20 mg hoʻokahi i ka lā, akā ʻaʻole ia ma mua o hoʻokahi mahina o ka hoʻokele. ʻO ka hoʻohana ʻana o kahi hoʻomākaʻa ʻia o 40 mg hiki ke loaʻa i nā maʻi koʻikoʻi wale nō ka maʻi a kūlike ʻia ma lalo o ka nānā ʻana o kekahi kauka.
Hoʻohanohano Atorvastatin
ʻO ka hana ikaika o ka lāʻau lapaʻau ka huakaʻi like, hiki ke waiho ʻia i loko o kahi papa i loko o kēia nāʻaina hou aʻe:
- 10 mg;
- 20 mg;
- 40 mg;
- 80 mg
Aia i ka mea hana, hiki i nā ʻaka a puni a oval paha, i loaʻa kahi palapala i kekahi o nā ʻaoʻao. Hoʻololi ʻia ka lāʻau lapaʻau ma nā pahu pepa. ʻO ka hapa liʻiliʻi o nā papa i loko o ka pākeke he 10 mau ʻāpana, ʻo ka lōʻihi ka nui o 300 ʻāpana.
Pono ka lawe ʻana i ka Atorvastatin ma kahi ʻōpū ʻole, no ka mea hui me ka meaʻai e hoʻopiʻi ai i ka make ʻana o ka mea ikaika.
Hōʻike ʻia ka lāʻau lapaʻau e ka bioavailability haʻahaʻa (12%). Loaʻa ka ʻike kiʻekiʻe piha i nā hola 1-2 ma hope o ka hoʻokele ʻana. ʻO ka hapalua-ola kahi 13 hola.
Hoʻoholo ʻia ka nui o ka lāʻau i ka hoʻomaka mua o ke kolamu a pono e koho pilikino ʻia no kēlā me kēia maʻi. ʻO ka inumapa mua ʻia he 10 mg hoʻokahi i ka lā. ʻO ka dosis ʻokoʻa loa i kēlā me kēia lā he 80 mg. Pono ka lāʻau ʻuma i ka ʻōpū ʻole. ʻO ka hoʻohui me ka meaʻai ka mea e hoʻonā ai i ka lilo ʻana o ka mea hana.
Ke hoʻohālikelike huakaʻi
ʻO nā lāʻau ʻelua e noʻonoʻo ʻia ana ka pūʻulu o nā statins synthetic. Hoʻohālikelike ʻia me nā mea ʻē aʻe o kēia papa, ʻike ʻia lākou i ka hoʻohaʻahaʻa ʻana i ka pae o TG. Eia naʻe, ʻaʻole like nā mea kanu a lākou.
Hoʻohālike
ʻO ke mau lāʻau nei ke kumu like o ka lawe ʻana - e hoʻohaʻahaʻa i ka cholesterol. Hoʻemi ʻia ko lākou hopena lāʻau lapaʻau i ka hoʻopau ʻana i ka hoʻoneʻe ʻia o HMG-CoA. ʻO ka hopena o kēia mau hopena, he hōʻemi ia o ka cholesterol i loko o nā hana a me ka hoʻōla ʻana o ka catabolism LDL cholesterol. ʻO ke ʻano o ka hōʻemi ʻana i kona neʻe 'ana i ka exponentially ma muli o ka nui o ka lāʻau lapaʻau.
E loaʻa nā hopena maikaʻi hou mai ka lawe ʻana iā Rosuvastatin a i Atorvastatin:
- ka holomua o ka endothelium me kāna kahakaha;
- ka hoʻōla maʻamau o nā kūlana rheological o ke koko;
- ka hoʻomaikaʻiʻana i ka kūlana o nā pā vascular a me ka atheroma.
ʻO nā ʻōkuhi no kā lākou hoʻohana ʻana i kēia mau maʻi:
- ʻO ka hypercholesterolemia o nā kumu mua, me ka homozygous hypercholesterolemia homozygous;
- hyperlipidemia type IIa a me IIb;
- III ʻano ʻano o ka dysbetalipoproteinemia;
- endogenous hypertriglyceridemia (ʻano IV).
Eia kekahi, ʻo nā lāʻau lapaʻau e hoʻohana ʻia no ka prophylaxis e nā mea maʻi me nā mea he nui no ka hoʻomohala ʻana o ka maʻi naʻau coronary, e like me:
- makahiki mamua o 55 makahiki;
- ulaula
- diabetes mellitus;
- haʻi maʻi
- haʻahaʻa kino (HDL) i ke koko;
- hoʻohui genetic.
Ua kau ʻia nō lākou i kēlā poʻe i ʻike ʻia i ka ischemia, i mea e hōʻemi ai i ka hopena o ka hoʻomā ʻana ʻana i ka angina pectoris, hōʻeha ʻana i ka puʻuwai a i ʻole hōʻeha.
Ke loaʻa nā lāʻau lapaʻau like contraindications. ʻAʻole i kuhikuhi ʻia ʻo Rosuvastatin a i Atorvastatin:
- me nā maʻi maʻi ma ka ʻaoʻao ikaika;
- i ka wā hāpai a me ka lactation;
- keiki a opio.
Me ka mālama aka, pono e hoʻohana ʻia nā lāʻau lapaʻau me:
- waiʻona wai;
- predisposition i myopathy;
- pilikia kaumaha ʻole.
ʻO nā hōʻike o ka hopena maikaʻi ʻole o ke kino e hoʻohālikelike ai i kēia mau lāʻau lapaʻau. Ke lawe ʻia lākou, ʻo ka hoʻomohala ʻana o nā ʻaoʻao like ʻole:
- nā hana ʻeha a me ka hoʻāhu ʻia, a me nā hopena ʻē aʻe mai ka pūnaehana neʻe i waena;
- nā hana kūpono ʻole, e like me ka nalowale o ka ʻono a i ʻole tinnitus paha;
- ʻeha ka ʻōpū, arrhythmia, angina pectoris;
- anemia, ke kala kala ʻole;
- bronchitis, pneumonia, bronchial asthma, nosebleeds;
- nausea a me na maemae e ae;
- ʻōpū, hōʻiliʻili i ka gout;
- ka māla ʻana
- ka hoʻomohala ʻana o nā maʻi urogenital;
- nā hopena dermatological;
- kahi hoʻololi i nā helu koko helu;
- ʻo ka waiwai kaumaha;
- ulu umauma;
- nā hōʻike hoʻohālikelike.
Loaʻa ka hopena therapeutic kiʻekiʻe loa ma hope o 4 mau wiki o ke ʻano me kēia mau lāʻau.
Ke lawe nei i kēia mau lāʻau lapaʻau, pono nā wahine o ka hānau ʻana ke hoʻohana i nā ala kūpono o ka contraception.
He aha nāʻokoʻa
ʻOiai nā mea like, like kēia mau lāʻau i nā hanauna o nā statins. ʻO Rosuvastatin kahi hana hou hou e hiki ai iā ʻoe ke hōʻemi i ka awelika a me ka nui loa o ka dosage o ka waiwai ikaika ma muli o ka hana ʻoi aku ka maikaʻi.
ʻO nā lāʻau lapaʻau i nīnau ʻia he mau ala like ʻole o ka hoʻopau ʻana:
- ua hoʻokaʻawale ʻia ka atorvastatin mai ke kino me ka hua bile ma ke ʻano o nā metabolites i loko e hoʻohuli ʻia e nā ʻenehana ate;
- rosuvastatin - i loli ʻole me ka moa.
ʻO Rosuvastatin kahi hana hydrophilic, a he waihona hoʻoheheʻe ʻia ʻo Atorvastatin i nā lem.
Ma ke ʻano 2 diabetes mellitus, ʻoi aku ka maikaʻi ma ke koho rosuvastatin, no ka mea, ʻaʻole i emi ka hopena i ke metabolism.
ʻOi ka mea palekana
Hōʻike nā hōʻike e like me ka ulu ʻana o nā hopena maikaʻiʻole i nā lāʻau ʻelua.
Ua hōʻike ʻia me ka maʻi maʻamau o ka lā 2, ʻoi aku ka maikaʻi o ke koho ʻana i nā statins hydrophilic, nona ka Rosuvastatin, no ka mea, he liʻiliʻi ka hopena o ka mauʻu i ka hopena o ka ʻaoli.
ʻOi ka uku
ʻO nā kumukūʻai o Rosuvastatin a me Atorvastatin i hilinaʻi i kekahi mau kumu:
- helu papa o kēlā me kēia pā;
- mea hana huahana;
- kulekele pili kumukūʻai;
- ka ʻāina o ke kūʻai ʻana i ka lāʻau.
Hāʻawi kekahi ʻoihana kūʻai pūnaewele kūʻai e kūʻai iā Rosuvastatin i nā kumukūʻai aʻe:
- 30 mau pā o 10 mg i hoʻolālā ʻia e Izvarino Pharma - 545.7 rubles;
- 30 mau pā o 10 mg i hoʻolālā ʻia e Vertex - 349.3 rubles;
- 60 papa o 20 mg, hana ʻia e Canonpharm Production LLC, - 830.5 mau rubles ;;
- 90 papa o 20 mg i haku ʻia e ka ʻoihana "North Star" - 1010.8 rubles.
Hiki ke kūʻai ʻia ʻo Atorvastatin ma ke kumukūʻai penei:
- 30 mau pā o 10 mg i hoʻolālā ʻia e ka hui ʻo ka North Star - 138 rubles;
- 30 mau papa o 10 mg i hoʻolālā ʻia e Ozone LLC - 65.4 rubles;
- 60 papa o 40 mg i hoʻohana ʻia e ka hui ʻo ka North Star - 361.4 rubles;
- 90 papa o 20 mg o ka hōʻailona Vertex - 799 mau rubles.
Mai nā kumukūʻai i ʻōlelo ʻia, ua maopopo leʻa ʻo Atorvastatin he lāʻau lapaʻau haʻahaʻa loa ma mua o Rosuvastatin.
ʻO wai ka mea maikaʻi - rosuvastatin a atorvastatin?
Loaʻa nā ʻikepili e pili ana i ka hoʻohālikelike ʻana i ka pono o kēia mau lāʻau lapaʻau ka hōʻike ʻana o ka lāʻau rosuvastatin he hopena hou aʻe i ka hoʻohaʻahaʻa ʻana i ka ʻike ʻana o ka cholesterol. Eia kekahi, aia kēia lāʻau lapaʻau i nā statins o 4 mau hanauna a hōʻike iā ia i ka hana pono e like me ka prophylactic no ka maʻi coronary artery.
Eia nō naʻe, ʻo ka koho i ka lāʻau lapaʻau e pono e hana e ke kauka komo i kēlā me kēia maʻi, e noʻonoʻo ana i kona ʻano pilikino, nā maʻi concomitant a me nā hiki kālā.
Hiki ke hoʻololi i ka rosuvastatin me ka atorvastatin?
ʻOiai ka mea o ka hoʻohālikelike o nā moʻo ʻana e hōʻike ana i ka mea ikaika o Rosuvastatin a me Atorvastatin, ʻaʻole ia ka mea like ʻole, he mau analogs a me ke hoʻololi ʻia. Eia nō naʻe, ma mua o ka neʻe ʻana mai i kekahi lāʻau i kekahi, pono e ʻimi mau i ke kauka, no ka mea, ua ʻokoʻa nā pharmacokinetics o nā mea ola, ma muli o kēia mau lāʻau e hoʻopili ʻia ai nā pūpū o ka puhiki a me nā ʻōpio i nā ala like ʻole, a me nā ala ʻē aʻe.
Hōʻike nā kauka i nā kauka
Grigory, 46 makahiki, Moscow: "ʻO ka mea nui e pono ai ka mea maʻi e ʻike i ka lawe ʻana i kēlā mau lāʻau lapaʻau ʻo ko lākou kumu ʻaʻole i kāpae i ka pono e pili i ka meaʻai i kauoha ʻia. ʻO ka mea mua, mahalo wau iā Rosuvastatin, no ka mea ua hōʻoia ʻia kona maikaʻi maikaʻi. . ^ E Ha yM.
ʻO Valentina, 34 makahiki, ʻo Novosibirsk: "Ke noʻonoʻo nei au e lawe i kēia mau lāʻau ma ke ʻano he prophylaxis maikaʻi o nā maʻi cardiovascular a me ka cerebral arteriosclerosis. Ke kuhikuhi nei au iā lākou i nā maʻi āpau i loaʻa ka cholesterol kiʻekiʻe."
Nā Hōʻike Mane no Rosuvastatin a me Atorvastatin
Nikolai: 52 mau makahiki ʻo Kazan: "ʻO ia wale nō ka maikaʻi o Atorvastatin ʻo ia ka uku haʻahaʻa. Noʻu, ua ukali ʻia kāna alakaʻi me ka nui o nā hopena ʻino: kūmau mau ke poʻo a me ke poʻo. Ma ka manawa like, hoʻomau ʻia ke kiʻekiʻe o ka cholesterol koko."
ʻO Svetlana, 45 mau makahiki, ʻo Murmansk: "Ma ke ʻōlelo a ke kauka, ua huli wau mai ka lawe ʻana i Atorvastatin i Rosuvastatin, no ka loaʻa pinepine o ka maʻi maʻi. Hiki iaʻu ke ʻōlelo ʻaʻole i ka lāʻau hou ke kumu e hoʻonā me kēlā ʻano.
