ʻO Gabapentin 300 kahi pūnaehana kemika e loaʻa kahi hopena anticonvulsant. ʻO ka waihona ʻāpana o ka lāʻau a kūʻai ʻia ma lalo o nā inoa inoa: Neurontin a me Gabagamma. Hoʻohana ʻia ka papa hana no ka mālama ʻana i nā manawa epileptic i loko o nā keiki mai 3 mau makahiki a hemo no ka hōʻeha ʻana o ka maʻi neuropathic ma nā maʻi maʻi. ʻAʻole ʻae ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana ma ke ʻano o nā injections.
Inoa Kūʻai ʻole honua
Gabapentin.
ʻO Gabapentin 300 kahi pūnaehana kemika e loaʻa kahi hopena anticonvulsant.
ATX
N03AX12.
E hoʻokuʻu i nā palapala a me ka ʻano
Loaʻa ka lāʻau lapaʻau ma ka palapala dosage formage a ma ka pepa capsule no ka hoʻoponopono waha. ʻAʻole i paʻi ʻia ma ampoules no ka maʻi maʻi.
Nā Palaki
ʻO ka papa keʻokeʻo kahi ʻano elliptical a pani ʻia i ke kiʻi enteric. Aia nā pilikia a me nā kālai ʻana o ka ʻoihana hoʻoneʻe ma nā ʻaoʻao ʻelua o ka lāʻau lapaʻau. Aia ka 1 papa i ka 800 mg o ka mea ikaika - gabapentin a me nā mea hoʻohui hou, aia ka:
- crospovidone;
- ʻōpala palaoa;
- magnesium stearate;
- Poloxamer 407.
ʻO ka membrane kiʻi'ōpiopio e pili ana i ka candelila (herbal wax), talc a me hyprolose. Hoʻopili ʻia nā papa i loko o 10 mau hakahaka i nā wili. Hiki i kahi paila pahu ke loaʻa nā paʻi 2, 5 a 10 paha.
Nā ʻatikā
Hāpai ʻia nā kapili me kahi peʻa gelatin o ke kala ʻōmaʻomaʻo. I loko o kēia palapala dosage ka pauma keʻokeʻo, kahi mea i hui pū ʻia ai nā mea hoihoi a me ka hoʻohui mea - 300 mg o gabapentin. E like me nā mea hoʻohui i hoʻohana ʻia i ka hana ʻana o:
- macrogol 6000;
- magnesium stearate;
- kalaka ʻaʻa;
- Houlūlele kalaiʻiwele waihoma.
Kūkulu ʻia ke kino capsule me ka titanium dioxide a me ka gelatin. ʻO kahi kīʻaha o nā ʻāpana: quinoline melemele a me ka indigo carmine e hāʻawi i ka ʻōmaʻomaʻo o ka pua i ka ʻāpana.
Loaʻa ka Gabapentin i loko o ka capsule form.
Ka hana lāʻau lapaʻau
Hoʻopili ka mea hoʻohui gabapentin i ke ʻano morphological o ka gamma-aminobutyric acid (GABA), e hana ana me kahi neurotransmitter i loko o ke kino. I kēia hihia, ʻokoʻa ka ʻano ikaika o ka neʻe ʻana aku i ka neurotransmitter ma kahi hana lapaʻau. ʻAʻole nakipili ʻo Gabapentin i ka barbiturates, GABA aminotransferase blockers, valproic acid a me nā kumumea o ka γ-aminobutyric acid, a laila ʻaʻole ia e hoʻopiʻi i ka hune a me nā wāwahi o GABA.
I ka papa o nā noi lāʻau lapaʻau, ua hoʻomaopopo ʻia ka nui o nā mea hoʻoikaika i kahi paʻakikī me ka alpha2-delta subunit o nā kalima kalepa, kahi i pili ai i ka hoʻomohala ʻana o ka ʻeha neuropathic. Ma muli o ka hana a Gabapentin, hoʻoneʻe ka hoʻokuʻu ʻana o nā papa kalaiwa i loko o ka wahi intercellular, e hoʻonui ana ka hiʻona o ka waila gamma-aminobutyric, ka make ʻana o nā sela nerve mai ka hoʻolaha ʻana i ka waikawa glutamic, a emi mai ka hoʻokuʻu ʻana o ka hopena o ka neurotransmitters o ka hui amine. A ʻo kahi hopena, ʻaʻohe pilikia o ka neuropathic.
Lapaʻau lāʻau
I ka wā e lawelawe mua ai, hiki i ka pūhui ikaika ke kiʻekiʻe i loko o ka plasma i loko o 2-3 mau hola. ʻO Bioavailability 60%. Hoʻopau nā papa āpau a me nā capsules i kā lākou membranes i ka hapa kokoke i ka ʻōpū liʻiliʻi ma lalo o ka hana o nā enzymes kūikawā (esterases). Hoʻomoʻa ʻia ka mea e neʻe nei i loko o nā paia o ka pā o ka pūpū, mai kahi e hoʻopalike ai i loko o nā moku.
ʻAʻole hōʻemi ka lāʻau lapaʻau i nā loli i loko o nā puʻuwai o ke ake.
ʻAʻole hōʻemi nā meaʻai i ka momona i ka emi ʻana o ka lae a me ka bioavailability o ka lāʻau. I ka moena vascular, emi iho ma lalo o 3% o ka pūhui neʻe e paʻa ai i nā protein plasma. ʻAʻole hōʻemi ka lāʻau lapaʻau i nā loli i loko o nā puʻuwai o ke ake. ʻO ka hoʻopau hapa-hapalua ke ola ma ka awelika o 5-7 mau hola. Ke waiho nei ʻo Gabapentin i ke kino ma o ka urinary system ma kāna ʻano kumu.
He aha ia e hoʻohana ai i ka?
Hoʻohana ʻia ka lāʻau lapaʻau ma ka monotherapy i nā keiki mai 12 a 18 paha makahiki a kau ʻia i ka hana hoʻohui me nā pākeke. Pono ke pono o ka lāʻau lapaʻau e hoʻopau i nā kahiki ʻokoʻa ma ka ʻaoʻao o ka epilepsy. Hoʻohana ʻia nā mea maʻi ma mua o 12 mau makahiki, me ka ʻole o ka hele ʻana o ka generalization a i ʻole i ka hele. I nā hihia pilikia, i kuhikuhi ʻia ʻo gabapentin me kahi kūlana paʻa o ka epilepsy i nā maʻi maʻi ʻoi aku ka 3 mau makahiki keu.
Hoʻonohonoho ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana no ka hoʻopaʻa ʻana i ka ʻeha neuropathic ma nā maʻi nā maʻi mai 18 makahiki o kona mau makahiki.
Nā Hoʻohui
Hoʻole ʻia ʻo ia e lawe i nā papa a me nā capsules i mua o ka nui o ka hiki ʻana o nā umauma kino i nā hana ikaika a kōkua.
Me ka mālama pono
Pono e mālama ʻia ma ka hihia ʻo ka maʻi maʻamau.
Pono e mālama ʻia ma ka hihia ʻo ka maʻi maʻamau.
Pehea e lawe ai i ka gabapentin 300
Hoʻokumu ʻia nā palapala palapala no ka hoʻokele waha ʻole me ka moʻo ʻole. Kaʻai ʻana i ka mīkini e alakaʻi i kahi emi o ka hoʻopili ʻana o ka lāʻau. Ke ke hoʻololi nei i kekahi lāʻau lapaʻau hou, ʻaʻole pono ʻoe e hoʻōki i ka lawe ʻana iā Gabapentin. Hoʻopili ʻia ke kau ʻana me kahi hōʻemi o ka nui o ka dosage ma luna o 7 mau lā.
No ka hoʻopau ʻana i ke kaʻina pathological i loko o kahi kinipōpō somatosensory e hōʻeha ai i ka maʻi neuropathic, pono ia e lawe i ka 900 mg i kēlā me kēia lā. Ua māhele ʻia ka nui o ka lā i kēlā me kēia lā i 3 pōkē. Me kahi hopena therapeutic haʻahaʻa, hiki ke hoʻonui mālie ka nui o ka nui a hiki i ka ʻae ʻia - 3.6 g i kēlā me kēia lā. Hoʻomaka ka lāʻau lapaʻau i ka 900 mg / lā a i ʻole ke hoʻoponopono ʻia ke ʻano lāʻau lapaʻau hou. I ka hopena hope loa, e hoʻonui pinepine ʻia ka nui o ka lā i kēlā me ka 0.9 g i koi ʻia ma luna o 3 mau lā.
- Ka lā 1 i lawe ʻia he 0.3 g;
- no nā lā 2, ʻo ka pinepine o ka hoʻohanaʻana he 2 mau manawa 300 mg;
- ma ka lā 3, 900 mg ka lawe ʻia, ka mahele ʻia i 3 iniha.
No ka hoʻokō ʻana i ka hopena antiepileptic, pono e lawe ʻia nā mea maʻi ma luna o 12 mau makahiki e lawe mai 900 a 3600 mg i kēlā me kēia lā. ʻO ka lōʻihi loa ma waena o nā pona i nā papa a i nā ʻōpona paha ʻaʻole eʻoi aku ma mua o 12 mau hola e pale ai i ka hoʻomohala ʻana o ka pī.
E kū'ē i ka papa o ka hikiʻole o ka renal, hoʻololi ke kauka i ka dosage i kēlā me kēia lā i kā Cl (clince clearance).
ʻO ka hoʻopukapukaʻana o Creinine, ml / min | Ka laʻenehana o kēlā me kēia lā, mg (pinepine o ka hoʻokele - 3 mau manawa i ka lā) |
oi aku ma 80 | Kapu pāʻālua |
mai 50 a hiki i ka 79 | 600-1800 |
30-49 | 300-900 |
oi aku a 29 | 300 mg i lawe ʻia me kahi pali o 24 mau hola. |
ʻAʻole pili ka mea ola i ka hana hana o nā mokupuni o Langerhans o nā pancreas.
Ma nā maʻi maʻi hemodialysis e hōʻike ʻia e lawe i ka 300-400 mg i ka lā mua o ke ʻano maʻi, ma hope nā hopena he 0.2-0.3 g 4 mau hola ma mua o ke kaʻina hana.
Me ka maʻi diabetes
ʻAʻole e hoʻopili ka mea ola i ka hana hana o nā mokupuni o Langerhans o ka pancreas a ʻole e hoʻopuka i ka hopena glycemic ma ke ʻano o ka glucose o ka glucose i loko o ke koko. No laila, ʻaʻole e pono i nā mea maʻi me ka maʻi maʻi maʻi hou e hoʻoponopono ʻia i ka lāʻau paipai ʻia.
Nā hopena hopena
ʻO nā hopena ʻaoʻao ka hopena me ka hewa kūpono o ka lāʻau lapaʻau. Ma ka hopena o nā hopena maikaʻiʻole i ka gabapentin, pono e hooki i ka lawe ʻana i ka lāʻau lapaʻau a ʻimi i nā ʻōlelo lapaʻau.
ʻŌpala Gastrointestinal
ʻO nā hoʻololi i ka ʻāpana kūwaho e hele pū me ka maʻi lemulewa, ka ʻeha o ka epigastric, ka ʻeha ʻana. E kūʻē i ke kua ʻana o nā hemahema o ke kūpaʻa, hiki i ka anorexia a i ʻole ka nui o ka makemake ʻana e ulu. Ma nā hanana lohi, loaʻa ka discoloration o ka enamel niho, puka nui ka waha, ulu nā pancreas a me nā leʻa i nā maʻi, ka piʻi o ka bilirubin a me ka hana o ka hepatocyte aminotransferases hoʻonui.
Hematopoietic mau hui
Hiki i ka thrombocytopenic purpura, hiki i ka leukocytopenia me ke kīpē o ka platelet.
Pūnaehana pīhoihoi waena
Hōʻike ʻia ka hoʻonāukiuki o ka ʻōnaehana ma nā hōʻailona e like me:
- ʻʻAla
- nele i nā pōkole i nā tendons;
- maʻi;
- lilo ka ʻuhane o ke kuhi (hoʻomāʻeha, hopohopo);
- nā hana hoʻonaninani;
- hiamoe
- nunui o nā wāwae;
- nāwaliwali laulā.
I nā hihia lohi, ataxia, nystagmus, choreoathetosis i loaʻa.
Mai ka papa huhū
Me ka hoʻohana mau ʻana o ka lāʻau lapaʻau, kahi uʻi maloʻo, lūlū o ka hanu, kū ʻana o ka ihu, a me ka maʻi o ka ʻōpū o ka hanu.
Ma ka ʻāpana o ka ʻili
Hoʻopuka i nā ʻili: keʻa, huehue, rashes, pruritus, a me ka maʻi Stevens-Johnson.
Mai ka pūnaehana cardiovascular
Hoʻomaʻemae ka nui o nā pālahalaha o ka vascular, piʻi aʻe ke koko a piʻi aʻe ka nui o ka naʻau.
Allergies
Inā loaʻa i ka mea maʻi ka predisposition i ka hōʻike ʻana i kahi hopena alaka, hiki i ka hoʻomohala ʻana o ka angioedema o ke kuʻopihi a me ka larynx, bronchospasm a me kahi hoʻihoʻi anaphylactic hiki. Me nā alakino e hōʻemi i ka paʻakikī, hiki i ka hoʻomohala ʻana o ka hōʻiliʻili o ka ʻili a me ka hōʻili ʻana o ka maka.
Nā ʻōlelo kikoʻī
I loko o nā hoʻokolohua hoʻokolohua o ka lāʻau lapaʻau, ʻaʻohe hōʻailona o ka haʻalele hānai ʻana me kahi koi koi o ka hoʻokō lāʻau. ʻO ka hōʻemi ʻana i ka dosage ka mea e pono ai e hōʻemi i ka hopena o ka lawe ʻana i ka epileptic a me ka hoʻokele waiwai i ka wa e pau ai ka lāʻau antiepileptic.
ʻAʻole kuhikuhi ʻia ka lāʻau lapaʻau no ka epilepsy me nā paroxysms convulsive.
Hiki i kahi urinalysis maʻamau ke hōʻike i kahi kūpono maikaʻi no ka proteinuria. I mea e pale aku ai i nā hoʻokolohua pinepine e ʻike i ka protein i ka urine, pono e paipai i nā limahana limahana e pili ana i ka lawe ʻana iā Gabapentin. E hana nā poʻe loea i kahi noiʻi me ka hoʻohana ʻana i ka acid sulfosalicylic.
Hiki i kahi urinalysis maʻamau ke hōʻike i kahi kūpono maikaʻi no ka proteinuria i nā mea maʻi e lawe gabapentin.
Hoʻohana i ka wā kahiko
ʻAʻole pono nā poʻe i ʻoi aku ma mua o 65 mau makahiki e hoʻoponopono hou i ka regimen dosage.
Koho ʻana iā Gabapentin i nā keiki 300
No nā keiki ma mua o 12 mau makahiki, ua kau ʻia kahi ʻano maʻamau o 900 mg i kēlā me kēia lā no ka mālama ʻana i nā kuʻuna.
Hoʻohana i ka wā hāpai a me ka lactation
ʻO ka lawe ʻana i ka lāʻau lapaʻau i ka wā hapai ʻaʻole ʻia. ʻO ke aʻo ʻana i nā haʻawina kūpono i ka hiki ʻana o Gabapentin e hele i ka pale o ka placental, ʻaʻole i mālama ʻia, no laila e loaʻa ka hopena i ka hanana ʻana o ka iwi i ka wā e ulu ana i ka lāʻau lapaʻau.
I ka wā mālama me ka gabapentin, pono e hoʻōki ka mālama umauma.
Ke keu
Me ka hōʻino ʻana o ka lāʻau lapaʻau, ka hoʻomohala ʻana:
- ʻʻAla
- hiamoe
- nā hana ʻino o ka ʻōlelo;
- makehewa;
- diplopia.
Pono ka mea pepehi ma ka ʻōpū o ka ʻōpū a hāʻawi i kahi adsorbent. No ka hoʻopauʻana i nā hōʻailona o kahi overdose, hana ke ʻano hōʻailona maʻi.
I kahi hihia o ka overdose, pono e holoi i ka mea ʻai i ka ʻōpū.
Hoʻopili pū me nā lāʻau ʻē aʻe
Me ka hoʻohana ʻana o ka gabapentin me nā lāʻau lapaʻau ʻē aʻe, ua ʻike ʻia kēia mau hopena penei:
- ʻAʻole paʻa ka mea ola i ka parakiʻi pharmacokinetic o nā ʻōlelo ulu i loko o ka wahine wahine a me ka ethinyl estradiol.
- Lawe ʻia ka Morphine i 2 mau hola ma mua o ka hoʻohana ʻana iā Gabapentin, no ka mea ke lawe ʻia nā lāʻau ʻelua i ka manawa like, ua hoʻonui ʻia ka AUC o ka gabapentin e 43%. Ua hoʻonui ʻia ka paepae hōʻeha. ʻO nā waiwai hapalua a me ka loaʻa ʻana o ke koʻo plasma kiʻekiʻe e loli, no laila, ma ka hoʻomaʻamaʻa ʻana i ka maʻi, ʻaʻole i pili kēia hopena i ka mālama pono o ka mea maʻi.
- Phenobarbital, Mexidol, Valproic acid a me nā lāʻau antiepileptic ʻē aʻe i ka hopena o ka lāʻau lapaʻau o Gabapentin.
- Me ka hoʻokele kūlike o nā antacids a me nā nā mea e pili ana i ka paʻakai konane a me nā paʻakai magnesium, kahi i hoʻokaʻawale i nā bioavailability o Gabapentin e 22% i hoʻopaʻa ʻia. I ka hopena, ua lawe ʻia ka anticonvulsant i 2 mau hola ma hope o ka lawe ʻana i ka antacids.
- ʻAʻole pili ʻo Probenecid i ka hoʻomaʻemaʻe kino o Gabapentin.
I ka wā o ka mālama ʻana me Gabapentin, pāpā paʻa ʻia ia i ka inu ʻawa. Hoʻonui ka Ethyl alkohol i ka hopena o ke kaumaha o ka pīhoihoi o ka nūna o ka neʻe, a hoʻonui i ka ulu ʻana o nā hopena ʻokoʻa. Ke kūʻē nei i ka hopena o ka hopena maikaʻiʻole o ka ekanan ma ka hana o ka ʻōnaehana kao, ka nāwaliwali ʻana o ka hopena therapeutic o Gabapentin e nānā.
Nā kuʻina
ʻO nā lāʻau lapaʻau e hiki ke hoʻololi iā Gabapentin e ka hana o ka hana a me ka ʻōmole hana:
- Katena
- Convalis;
- Neurontin;
- Tebantin;
- Gabagamma
Ke hoʻohuli nei i kekahi lāʻau lapaʻau e lawe ʻia ma lalo o ka mākaʻi loea koʻikoʻi ma muli o ka hopena o ka hana kuʻi.
ʻO nā kūlana hoʻomaha ʻo Gabapentina 300 mai ka lāʻau lapaʻau
ʻAʻole kūʻai ʻia ka lāʻau lapaʻau me ka loaʻa ʻole o kahi lāʻau lapaʻau i ka ʻōlelo Latin.
Hiki iaʻu ke kūʻai me ke kī ʻole
ʻAʻole hiki ke kūʻai aku i kahi lāʻau lapaʻau anticonvulsant me ke aʻo ʻole ʻana i ka lāʻau lapaʻau, no ka mea inā lawe maikaʻi ʻoe iā Gabapentin, hiki iā ʻoe ke ʻike i ka hoʻoweliweli ʻana i ka hana ʻoiau, ka helehelena o ka mamae neuropathic a me nā hopena hopena.
Ehia ka gabapentin 300
Hoʻololi ʻia ke kumukūʻai kūpono o kahi lāʻau mai 349 a 464 mau rubles.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Ke hāpai ʻia nei e mālama ʻia nā papa papa a me Gabapentin 300 i kahi ma ka haʻahaʻa haʻahaʻa a i nā pae a hiki i + 25 ° C.
ʻO ka lā kau
3 mau makahiki
Gabapentin 300
CJSC Canonfarm Production, Rūsia.
Hoike ʻia ma Gabapentin 300
Ma nā kūkākūkā lapaʻau he mau manaʻo maikaʻi mai nā mea maʻi e pili ana i ka lāʻau lapaʻau a me nā ʻōlelo aʻoaʻo o nā neurologists.
Kauka
Ramil Dzhumabaev, neurologist, 44 makahiki, Omsk
Loaʻa ka hopena therapeutic i ka wikiwiki. Manaʻo wau ʻo Gabapentin kekahi o nā lāʻau lapaʻau loa loa no ka hoʻomaha ʻana o ka maʻi neuropathic a loaʻa i nā hopena anticonvulsant. Akā i ka nui o nā manawa, ʻike wau i ka hopena o ka hopena o ka hopena: myalgia, pain back, fractures, i nā hihia koʻikoʻi, ulu nā amnesia.
ʻO Ivan Tikhonov, neurologist, 51 makahiki, Krasnoyarsk
Maikaʻi ʻo Gabapentin i ka hōʻeha o ka maʻi neuropathic o kekahi ʻano kūloko, ʻaʻole i ʻae ʻia e hoʻopaʻa ʻia e nā lāʻau anti-inflammatory non-steroidal. Me ka hoʻohana ʻana i ka lōʻihi, pono ʻoe e makaʻala. Hoʻomaopopo ka poʻe maʻi i ka hoʻopiʻi a me nā kaumaha. Pono e hoʻomoe ʻia nā dosages a me nā pinepine o ka hoʻokele e nā kauka komo.
ʻO nā maʻi maʻi
Anastasia Koshkina, 34 makahiki, Moscow
Lawe wau i ka gabapentin me ka hoʻokolohua o ka maʻi neuropathy maʻi sensory-motor. Ke lawe nei, he hopena analgesic, akā nāwaliwali. Ma hope o koʻu inu ʻana i nā papa, ʻike wau i ka nahalike, nalowale ka koina o nā neʻe, huina ʻole. Manaʻo wau e moe ana ma hope o nā papa no hoʻokahi hola.
Lilia Alekseeva, 42 makahiki, Tomsk
Kōkua nui ka lāʻau lapaʻau me ka epilepsy. Hoʻolohe loa au e like me nā kauoha. Loaʻa iā ia kahi hopena anticonvulsant malū. ʻAʻohe mea i hōʻeha ʻia i ka wā e lawe nei i ka lāʻau. I koʻu lawe ʻana i ka hoʻomaha, hoʻomaka lākou e hoʻomaka hou. ʻO nā hopena hopena, hiki iaʻu ke hōʻike i ka dizziness, ka mea e hoʻonui ai i ke kakahiaka.