I ka papa inoa o nā lāʻau lapaʻau hypoglycemic maikaʻi loa, e haʻi ʻia ana ʻo Janumet. ʻO kāna hiʻohiʻona ka hui pū ʻana, hiki iā ia ke hoʻokō i nā hopena kiʻekiʻe ma ke kumukūʻai haʻahaʻa.
Inoa Kūʻai ʻole honua
INN lāʻau - Metformin + Sitagliptin.
I ka papa inoa o nā lāʻau lapaʻau hypoglycemic maikaʻi loa, e haʻi ʻia ana ʻo Janumet.
ATX
ʻO ka helu ATX ʻo A10BD07.
E hoʻokuʻu i nā palapala a me ka ʻano
ʻO kahi papa kiʻi wale nō o Janumet 50 nā papa, akā naʻe, heʻokoʻa ka ʻano ʻē aʻe.
ʻO ka mea nui ka lāʻau lapaʻau e loaʻa i kēia mau mea ikaika:
- sitagliptin phosphate monohydrate - ma kahi o 64.25 mg (ua ʻike kēia ʻike i ka 50 mg o ka sitagliptin);
- metformin hydrochloride - hiki i ka nui o kēia kumuhana ke hiki i 500, 850 a i ʻole 1000 mg (e like me ka nui o ka hōʻike ma ka lāʻau).
ʻO nā mea kōkua
- sodium fumarate;
- povidone;
- wai maʻemaʻe;
- sodium lauryl sulfate.
ʻO nā papa Biconvex, kāwili ʻia nā kiʻi ʻoniʻoni, maʻa ma ka ʻaoʻao a he paʻakikī ma kekahi. Kūlike ka ʻili i ke kala ʻana: ka ʻulaʻula kukui (50/500 mg), ka pink (50/850 mg) a me ka ʻulaʻula (50/1000 mg).
Hoʻokomo ʻia nā papa i loko o nā pani o 14 pcs. Aia paha i kahi pahu pepa mai ka 1 a 7 mau papa.
Ka hana lāʻau lapaʻau
ʻO nā papa Yanumet - kahi lāʻau lapaʻau i hui pū ʻia. Loaʻa iā 2 mau lāʻau hypoglycemic hoʻomaikaʻi maikaʻi i kēlā me kēia hana. ʻO ka lawe ʻana i nā paila e kōkua i ka hoʻokō ʻana i ka mana hypoglycemia i nā maʻi me ka maʻi II.
ʻO ka lawe ʻana i nā paila e kōkua i ka hoʻokō ʻana i ka mana hypoglycemia i nā maʻi me ka maʻi II.
Sitagliptin
Loaʻa i kēia māhele nā waiwai o kahi inhibitor enzyme selly maikaʻi loa (DPP-4). Hoʻohana pinepine ia ma ka mālama kino ʻana o ka maʻi II mellitus type II.
Hoʻololi ka DPP-4 inhibitors ma o ka hoʻopohapū i nā incretins. Ke hoʻokaʻawale nei i ka hana o DPP-4, hoʻonui ka sitagliptin i ka ke ʻano o ka glucose-dependotio glucose-hilinaʻi i ka polypeptide (HIP) a me ka pebide like-glucagon 1 (GLP-1). ʻO kēia mau mea hāmeʻa he mau wikiō ikaika mai ka ʻohana incretin. ʻO kā lākou hana, ʻo ia ke komo i ka hoʻoponopono o ka homeostasis glucose.
Me nā glucose koko maʻamau a kiʻekiʻe paha, ʻo ka HIP a me GLP-1 ke koi i ka synthesis o ka insulin e nā puna o ka pancreas. Hiki nō hoʻi i ka GLP-1 ke hana i ka hana o ka glucagon i ka pancreas, e hōʻemi ana i ka hoʻohuʻohu o ka glucose i loko o ke akea.
ʻO ka meaʻokoʻa o ka sitagliptin ka mea i hoʻopaʻa ʻia ai i nā dosis therapeutic i manaʻo ʻia, ʻaʻole kēia mea i pale i ka hana o nā enme pili, me ka DPP-8 a me DPP-9.
Metformin
ʻO kēia ʻāpana pū kekahi i nā waiwai hypoglycemic. Ma lalo o kona mana, hoʻopilikia ʻia ka poʻe e kaʻi ʻana i ke ʻano diabetes mellitus type II. ʻO kēia ka mea i hoʻākāka ʻia e ka hōʻemi ma nā pae o ka glucose o ka glucose a postprandial a me basal.
ʻO ka papa lāʻau lapaʻau o ka hana o ka metformin ka mea ʻokoʻa kū like o ka hana a ka poʻe hypoglycemic agents, ka poʻe i nā hui o ka lāʻau lapaʻau. Ke kōkua nei ka hoʻohana ʻana i ka lāʻau lapaʻau e hiki ke hoʻokō i kēia mau kuhikuhi aʻe:
- hoʻemi ka hana glucose i loko o ka ate;
- ua emi ka nui o ke kōpona o nā glucose i nā loko;
- wikiwiki ka hopu peripheral a me ka pau ʻana o ka glucose i loko o ke koko ke hoʻoikaika nei i ka hoʻololi ʻana i ka insulin i hoʻopaʻa ʻia.
ʻO ka pōmaikaʻi o kēia māhele (hoʻohālikelike me ka sulfonylurea) ʻo ka nele o ka hoʻomohala ʻana o ka hypoglycemia a me ka hyperinsulinemia.
Lapaʻau lāʻau
ʻO ka nui o ka lāʻau ʻo Yanumet e pili pono ana i ka hoʻoponopono o ka metformin a me ka sitagliptin i hoʻokaʻawale. ʻO ka bioavailability o metformin kahi hōʻailona o 87%, sitagliptin - 60%.
Hoʻāʻe ʻia nā mea koʻikoʻi o ka mana i loko o nā keiki.
ʻO ka hana nui loa o sitagliptin e loaʻa ai i ka hola 1-4 ma hope o ka hoʻokō waha. ʻAʻole pili ka ʻai i ka meaʻai i ka helu a me ka nui o ka pā ʻana. Hoʻomaka ka hana Metformin ma hope o 2 mau hola. Me ka loaʻa o ka meaʻaiʻai nui, ua hoʻemi ʻia ka helu kōpili.
Hoʻāʻe ʻia nā mea koʻikoʻi o ka mana i loko o nā keiki.
Nā hōʻailona no ka hoʻohana ʻana
Hoʻolālā ʻo Yanumet e hoʻokau i ka mana hypoglycemia i nā maʻi me nā maʻi maʻi type 2. Kuhi nā kauka i nā lāʻau lapaʻau i kekahi mau hihia:
- I ka haʻalele ʻana o ka hopena i makemake ʻia mai ka lapaʻau me ka Metformin. I kēia hihia, hoʻomaikaʻi ʻia ka hoʻomākaukau ʻana i ka glycemic profile a me ke ʻano o ke ola o ka maʻi maʻi.
- I ka hui pū me nā gamagon reseptor gamma.
- Me ka uku uku kōpiha piha mai nā inikini insulin.
Nā Hoʻohui
ʻAʻole ikaika e lawe i ka lāʻau me ka:
- ka naʻau o kēlā me nā mea i ka hana o nā papa;
- maʻi diabetes type II;
- maʻi koma maʻi;
- nā maʻi maʻi āpau;
- ʻano haunaele;
- pilikia hooili;
- ka lawe ʻana i ka lāʻau i loko o ka iodine;
- uha kapili āpau;
- nā maʻi i hele pū me ka nele o oxygen;
- huapoʻi, pōkole;
- hapai a me ka umauma;
- malalo o na makahiki he 18.
Me ka mālama pono
Wahi a nā ʻōlelo kuhikuhi, ua kuhikuhi ʻia ka lāʻau lapaʻau i nā poʻe maʻi me ka nui o ka makaʻala.
Pehea e lawe ai iā Janumet 50?
Lawe ʻia nā papa i ke kakahiaka ma kahi ʻōpū ʻole me nā meaʻai. Me kahi komo o ka manawa ʻelua, lawe ʻia ka lāʻau lapaʻau i ke kakahiaka a i ke ahiahi. Kūkulu ke kauka i ka dosis hoʻokahi, ʻoiai ke nānā nei i ke kūlana o ka mea maʻi, ʻo kona makahiki a me ka hoʻoponopono regimen ʻokoʻa.
- Inā ʻaʻohe mana o ka glycemic me ka metformin i ka nui loa i kā ʻia. Kuhi ʻia nā mea maʻi iā Janumet 2 mau manawa i ka lā. ʻAʻole pono ka nui o ka sitagliptin i luna o 100 mg i kēlā me kēia lā, koho ʻia ke ʻano o ka metformin i kēia manawa.
- Inā hele mai kahi hoʻololi mai ka mālama ʻana me ka metformin + sitagliptin complex. ʻO ke ʻano kumu mua o Yanumet i kēia hihia ke koho like ʻia ma mua.
- I ka haʻalele ʻana o ka hopena e pono ai e lawe i kahi hui o ka metformin a me ka sulfonylurea. ʻO ka nui o ka ʻōlelo o Yanumet e pono me ka nui o ka nui o ka sitagliptin i kēlā me kēia lā (100 mg) a me nā kaila o ka metformin o kēia manawa. I kekahi mau hihia, ua ʻōlelo ʻia ka lāʻau lapaʻau e hui pū me ka sulfonylurea, a laila e hōʻemi ʻia ka dosage o ka hopena. Inā ʻaʻole, aia kahi hopena o ka hypoglycemia.
- I ka haʻalele ʻana o ka hopena i makemake ʻia mai ka lawe ʻana i ka metformin a me kahi agonist PPAR-y. Kuhi aku nā kauka i nā papa i loko o Yanumet e loaʻa ana i kēia lā o ka metformin i kēlā me kēia lā a me 100 mg o ka sitagliptin.
- Hoʻohui i kahi paʻakikī o ka metmorphine a me ka insulin i ka lā maʻamau i kēlā me kēia lā o nā papa i loaʻa iā 100 mg o ka sitagliptin a me kahi pānaʻi no ka metformin. Pono e hoʻemi ʻia ka nui o ka insulin.
Me ka maʻi diabetes
Hoʻolālā kū maoli nā papa i nā maʻi me ka maʻi maʻamau 2. Hoʻopilikia ka poʻe i loaʻa ʻana i ka maʻi type 1.
Nā hopena hopena o Yanumet 50
He nui nā hopena ʻaoʻao o kēia hypoglycemic agent. Pono ke kauka e hoʻomaʻamaʻa i ka mea maʻi me lākou, ʻoiai inā i hōʻike ʻia kekahi a me kekahi mau hōʻailona, pono ʻoe e hōʻole i ka lawe ʻana i ka lāʻau lapaʻau. Ma hope koke o kēia, pono e kamaʻilio i kahi kauka, kahi e nānā ai i nā helu koko a me ka ʻike ʻana o ka lactate.
ʻŌpala Gastrointestinal
Mai ka gastrointestinal tract, ʻike pinepine ʻia ka ʻaha metallic i loko o ka waha. ʻOi aku ka maʻamau o ka paila a me ka luaʻi. Flatulence a me ka hoʻomohala ʻana o ke ʻano maʻi i hiki ke hoʻomaka i ka hoʻomaka. Hoʻomaopopo kekahi mau maʻi i ka hōʻeha o ka ʻōpū.
ʻO ka wili kekahi o nā hopena ʻaoʻao o ka lāʻau lapaʻau.
Mai ka ʻaoʻao o ka metabolism
Nui nā poʻe maʻi i kahi maʻi metabolic i loko o ke kino. Hoʻopili ʻia kēia me hypoglycemia. I nā hihia pinepine, ʻike ʻia ka hypothermia, ke kūkulu ʻia ʻana o ka pilikia o ka hanu, ke ʻano o ka hiamoe, ka ʻeha o ka ʻōpū, a me ke hypotension.
Ma ka ʻāpana o ka ʻili
Hōʻike pinepine ka ʻeha o ka ʻeha i ka hana ʻana i nā papa i hana ʻia i nā papa. I kēia mea, hele mai ka dermatitis, ke kō a me ka ʻeha. ʻOi aku ka maʻamau o ka maʻi Stevens-Johnson a me ka vasculitis cutaneous.
Mai ka pūnaehana cardiovascular
I nā hihia pinepine, hiki mai ka anemia megaloblastic ma muli o ka malabsorption o ka vitamin B12 a me ka folic acid.
Allergies
Hōʻike ʻia ka maʻi āpau e ka ʻeha a me nā ʻūlū.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
ʻAʻole loaʻa ka hopena lāʻau i ka wikiwiki o ka hopena psychomotor a me ka nānā. Eia naʻe, ʻo ka lawe ʻana i ka sitagliptin hiki i ka hiamoe a me ka nāwaliwali. No kēia kumu, pono i ka hana ʻana i ke kaʻa a me nā ʻano hana ʻē aʻe e hana me ka akahele loa.
Nā ʻōlelo kikoʻī
ʻO kahi papa lōʻihi o ka lawe ʻana i nā paila e pono ai ke nānā mau ʻana o nā keiki.
Inā loaʻa i ka mea maʻi ka diagnostic a therapeutic kaʻina hana me ka iodine e loaʻa ana i nā lāʻau, i pono ʻo Janumet e hoʻohana ʻia he 48 mau hola ma mua a ma hope.
I nā maʻi me ka pancreatitis a me nā maʻi pūpū, hiki i nā lāʻau ke hoʻonui i nā hōʻailona o ka maʻi. I mea e pale ai i kēia, pono e hoʻoponopono ke kauka i ka hewa a mālama pono i ka ʻano o ka mea maʻi.
I nā maʻi me ka pancreatitis, e hoʻonui paha nā papa i ka hōʻailona o ka maʻi.
Hoʻohana i ka wā hāpai a me ka lactation
ʻAʻole ʻōlelo ʻia nā wahine i ka wā hāpai a me ka lactation i kēia lāʻau lapaʻau hypoglycemic. I kēlā mau kūlana, ua hoʻokumu ʻia ka mālama ʻana i ka lawe ʻana i ka insulin.
Koho ana o Yanumea i na keiki he 50
ʻAʻohe data lapaʻau e pili ana i ka hopena o ka lāʻau hoʻohui i ke kino o nā keiki. No kēia kumu, ʻaʻole i kuhikuhi ʻia ʻo Janumet no nā maʻi ma lalo o nā makahiki 18.
Hoʻohana i ka wā kahiko
Ua ʻōlelo ʻia nā poʻe ʻōpio i kēia lāʻau lapaʻau, akā ma mua o kēia, e koi ʻia ke ʻano o ke ʻano o nā pūpū.
Ke noi no ka hana renal haukapole
ʻAʻole ʻōlelo ʻia ka lāʻau lapaʻau no nā poʻe me nā maʻi puʻupuʻu koʻikoʻi (me ka poʻe me ka clealce haneli haʻahaʻa).
Hoʻohana no ka hana lawelawe lēwa
I ka hihia o ka palaualelo koʻikoʻi, lawe ʻia ka Janumet ʻaʻole ʻōlelo ʻia. ʻO kēia ma muli o ka hopena o ka lactic acidosis.
ʻO ke kauā o Yanumet 50
Inā ʻoi aku ka mea hoʻomanawanui i ka hopena therapeutic o ka lāʻau lapaʻau, hoʻopili kēia i ka hoʻomohala ʻana o ka acidosis lactic. E hoʻopaʻa i ka kūlana, hana ʻia ka lavage gastric a ʻōlelo ʻia ʻo hemodialysis.
ʻO kekahi hōʻailona hou o kahi overdose ka hypoglycemia. Me ka hōʻike maʻalahi ʻana, e hōʻike ʻia ka mea maʻi e ʻai i nā meaʻai i kiʻekiʻe me nā ʻaina. Pono e hypoglycemia maʻalahi a i ʻole e ukali ʻia e Glucagon injection a ʻole Dextrose i ka hopena. Ma hope o ka hoʻomanawanui hou ʻana o ka mea maʻi, hāʻawi lākou i nā meaʻai momona.
E hoʻopaʻa i ke kūlana ma kahi o ka overdose, ua kuhikuhi ʻia nā hemodialysis.
Hoʻopili pū me nā lāʻau ʻē aʻe
Me ka mālama paʻakikī o ka mea maʻi, pono e noʻonoʻo ke kauka i ka hoʻohālikelike o nā papa me nā lāʻau ʻē aʻe.
ʻO ka hana a Yanumet e palupalu i mua o nā lāʻau i lalo nei.
- Phenothiazine;
- Glucagon;
- diuretics thiazide;
- nikolinic acid;
- nā kahalauna;
- o nā hormone thyroid
- Isoniazid;
- nā mea estrogen;
- paeʻāina
- nā antagonis kaluna;
- Phenytoin.
Hoʻohui ʻia ka hopena hypoglycemic i ka wā i hoʻohana pū ʻia me nā lāʻau aʻe:
- nā huahana-anti-inflammatory stidal;
- Insulin
- beta-blockers;
- kumuliiu aoli;
- Ookikaumaha;
- Acarbose;
- Cyclophosphamide;
- ACE a me MAO inhibitors;
- derivatives o clofibrate.
Me ka cimetidine, hiki i ka hopena o ka acidosis.
Me nā derivatives sulfonylurea a i ʻole insulin. Loaʻa pinepine i laila hypoglycemia i ka haʻalele ʻana o ka hoʻoponopono hoʻoponopono ʻia.
Hoʻolaha ka waipuna
I ka hui pū me ka waiʻona, hoʻonui ka hopena o nā hopena ʻaoʻao.
Nā kuʻina
I waena o nā metalae ua kapa ʻia:
- Amaryl M;
- Yanumet Long;
- Douglimax;
- Velmetia;
- Avandamet;
- Kūkākūkā;
- Glibomet;
- Kalepui Met;
- Kuʻunaʻi;
- Hōʻailona.
Waihue huaʻōlelo waiho nā huaʻōlelo
I loko o nā haleʻai, ua kuhikuhi ikaika ia.
Hiki iaʻu ke kūʻai me ka loaʻa ʻole o ka hōʻailona?
ʻAʻole hiki ke kūʻai ʻia ka lāʻau lapaʻau no kēia pūʻulu me ka ʻole o ka lāʻau lapaʻau.
Kumu kūʻai no Yanumet 50
ʻO ke kumukūʻai o ka lāʻau lapaʻau ma Ukraine, Lūkia a me nā ʻāina ʻē aʻe e hilinaʻi ana i ka nui o ka wai i hāʻawi ʻia i nā papa a me nā ʻāpana he nui i hāʻawi ʻia i loko o ka waihona. Ma nā hale kūʻai lāʻau ma Moscow, ʻo nā kumukūʻai no Yanumet penei:
- 500 mg + 50 mg (56 pcs.) - 2780-2820 mau rubles;
- 850 mg + 50 mg (56 pcs.) - 2780-2820 mau rubles;
- 1000 mg + 50 mg (28 pcs.) - 1750-1810 rubles;
- 1000 mg + 50 mg (56 pcs.) - 2780-2830 mau rubles.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Pono ke mālama i ka lāʻau lapaʻau ma kahi e mālama ai mai ka lā māmā a me ka māla. E pono ke ana o ka mahana a + 25 ° C.
ʻO ka lā kau
Hiki i ke lāʻau lapaʻau ke lilo no 2 mau makahiki.
Mea hana
Kuhi ʻia nā papa e ka hui lāʻau lapaʻau ʻo Patheon Puerto Rico Inc. i Kapalakiko. Hoʻopuka ʻia ka lāʻau lapaʻau e nā ʻoihana like ʻole:
- Merck Sharp & Dohme B.V, aia ma Netherlands;
- OJSC "Kahua lāʻau lapaʻau lāʻau" AKRIKHIN "ma Rūsia;
- ʻO Frosst Iberica ma Sepania.
Hoʻokuʻu ʻia ka lāʻau lapaʻau mai nā lāʻau lapaʻau e like me ke kumu lāʻau.
Hoike e pili ana iā Yanumet 50
Alexandra, ka mea endocrinologist, ʻike i ka lāʻau lapaʻau no 9 mau makahiki, ʻo Yaroslavl.
Ua hiki i ka lāʻau lapaʻau ke hōʻoia i kona pono i nā hoʻokolohua lapaʻau a hoʻomaʻamaʻa. Hoʻomaopopo pinepine wau i kēia mau kīleʻa no kaʻu mau maʻi me ka hilinaʻi i ka insulin. Loaʻa nā hopena ʻaoʻao. ʻO ke koi nui ka dosage kūpono.
Valery, endocrinologist, ʻike i loko o ka lāʻau lapaʻau no 16 mau makahiki, ʻo Moscow.
ʻAe ʻo Yanumet e hiki ai iā ʻoe ke hoʻokō i ka hopena i makemake ʻia i nā wā he nui i hiki ʻole ke hoʻomalu ʻia nā paʻakai gula me Metformin. Ua hopohopo kekahi poʻe maʻi e huli i kēia ʻano o ka mālama ʻana ma muli o nā hopena hopena a me ka hopena o ka hypoglycemia. Eia kekahi, ma ka hoʻomaʻamaʻa ʻia, hiki ke kapa ʻia nā hihia like ʻole i kahi ʻanilua, ʻoiai inā ʻike ʻia ka pona kūpono a me nā ʻōlelo loiloi a kekahi kauka.
