Tegretol CR - kahi lāʻau antiepileptic e hāpai nei i ka paepae o ka mākaukau e hōʻoiaʻiʻo, me ia e pale ai i ka loaʻa ʻana o nā kū kaua.
Inoa Kūʻai ʻole honua
Carbamazepine.
Tegretol CR - kahi lāʻau antiepileptic e hāpai i ka paepae o ka mākaukau e hōʻoiaʻiʻo ana.
ATX
ʻO ka helu ATX ʻo N03AF01.
E hoʻokuʻu i nā palapala a me ka ʻano
Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa pani. Aia nā papa i kahi bordvex oval.
ʻO ka hoʻolaha hua e pili ana i nā papa he 200 mg a i ʻole 400 mg. ʻO ka mea hana a ka caramazepine.
Loaʻa nā papa ʻelua 200 mg i nā kālena a me nā ʻāpana he 50 mau ʻāpana. I loko o kahi pūʻulu o nā 5 mau mauʻaoʻao he 10.
Loaʻa nā papa 400 mg i nā ʻāpana o 30 mau ʻāpana. Ma loko o nā pūpū 3 mau palaka he 10 mau ʻāpana.
Ka hana lāʻau lapaʻau
Hōʻike ʻia ka Carbamazepine no ka hoʻomaha ʻana i nā holo kikowaena. ʻO ka mea kumu nui o ka lāʻau lapaʻau ka mea hiki i ka dibenzoazepine derivative. Loaʻa ia kahi hopena antiepileptic pū me ka neurotropic a me ka psychotropic.
ʻAʻole aʻo ʻia ke ʻano lāʻau lapaʻau i ka lāʻau. Aia kekahi ʻike e pili ana ka hana ikaika i nā membran cell of neurons, e hoʻopaʻa ana iā lākou a pale aku i ka overexcitation. Hoʻopilikia ʻia kēia mea ma muli o ke kaohi ʻana o nā neʻe neuronal wikiwiki, no laila aia ka hyperactivation o nā hana nerve.
Hoʻohana ʻia ka hoʻohana ʻana o Tegretol i nā maʻi me ka epilepsy i ka hoʻowali ʻia o nā hōʻailona noʻonoʻo pono.
ʻO ka hana nui o ka hana o ka lāʻau lapaʻau e pani ana i ka hoʻihoʻi hou ʻana o nā neurons ma hope o ka depolarization. ʻO kēia ke kumu o ka hana ʻole ʻana o nā kaola ion e hāʻawi i ka halihali sodium.
Ua hōʻike ʻia nā haʻawina ʻo ka hoʻohana ʻana o Tegretol i nā mea maʻi me ka epilepsy i hele pū me ka hoʻomakeʻa ʻana i nā hōʻailona noʻonoʻo ponoʻeha: nā pilikia kaumaha, ka huhū a me ka hopohopo nui.
ʻAʻohe mea i maopopo i ke ʻano o ka carbamazepine e pili ana i ka helu o nā hopena psychomotor a me nā hiki ʻana aku i nā mea maʻi. I ka wā o kekahi mau noiʻi, ua loaʻa nā ʻikepili hakakā, ua hōʻike kekahi e hoʻomaikaʻi ka lāʻau lapaʻau i nā pono cognitive.
Hiki i ka hopena neurotropic o Tegretol ke hoʻohana iā ia no ka mālama ʻana i nā pathologies neurological. Ua kuhikuhi ia no nā maʻi me ka neuralgia n. trigeminus no ke kōkua o nā hōʻeha o nā hōʻeha e kū mai i ka ʻeha.
ʻO nā mea maʻi me ka hoʻohaʻahaʻa ʻawaʻawa ua kuhikuhi ʻia e hōʻemi i ka hopena o nā huhū.
ʻO nā mea maʻi me ka hoʻohaʻahaʻa ʻawaʻawa ua kuhikuhi ʻia e hōʻemi i ka hopena o nā huhū. Hoʻonui ʻia hoʻi i ka paʻakikī o nā hōʻike palaka o ka maʻi convulsive.
I ka poʻe me ka maʻi maʻi maʻi insipidus, hoʻohana ka hoʻohana ʻana i kēia lāʻau i ka diuresis.
Hoʻohana ʻia ka hopena psychotropic o tegretol e mālama i ka pilikia o ka noʻonoʻo. Hiki ke hoʻohana liʻiliʻi a hui pū me ka hoʻohui ʻana me nā antipsychotics, antidepressants. ʻO ka hoʻonui ʻia o nā hōʻailona manic e wehewehe ʻia e kahi hiki ke hoʻoneʻe i nā hana o ka dopamine a me norepinephrine.
Lapaʻau lāʻau
Hoʻopuka wale ʻia ka hana ikaika ma o ka mucosa ʻawa. Ke hoʻolōʻihi nei kona hoʻokuʻu ʻana mai i nā papa, hiki i kahi hopena lōʻihi. Loaʻa ka pae kiʻekiʻe loa o kahi mea i loko o ke koko ma kahi o 24 mau hola. ʻOi ka haʻahaʻa o ka haʻahaʻa ma mua o ka neʻe ʻana i ka hana maʻamau o ka lāʻau.
Ma muli o ka lohi ka wikiwiki o ka mea ikaika, flultuations i loko o kona hoʻomoʻa ʻana i ka plasma he mea waiwai ʻole. ʻO ka bioavailability o ka carbamazepine ke lawe nei i nā papa pālahalaha e hōʻemi ʻia e 15%.
Ke komo nei i ke kahe, hiki i ka mea hana ke kau aku i nā peptides e 70-80%. E kāʻei i ka placenta a i loko o ka waiū umauma. Hiki i ka ʻike o ka lāʻau lapaʻau i nā lā hope aʻe ma mua o 50% o ka hōʻailona like i ke koko.
ʻO ka bioavailability o ka carbamazepine ke lawe nei i nā papa pālahalaha e hōʻemi ʻia e 15%.
Hoʻomau ka metabolism o ka hana ikaika ma lalo o ke ʻano o ka pehu o nā huina o ka huina. I ka hopena o ka hoʻohuli ʻana i ka kemika, ua hoʻokumu ʻia nā metabolite ikaika o ka carbamazepine a me kāna pūhui me ka waika glucuronic Eia kekahi, ʻokoʻa kekahi unuhi o ka metabolite hana ʻole.
Aia kekahi ala metabolic i pili ʻole i ka cytochrome P450. Pēlā ke kūkulu ʻia nei nā pūhui monohydroxylated o ka carbamazepine.
ʻO ka hapalua hapalua o ka hana ikaika he 16-36 hola. Hoʻohana ʻia ka lōʻihi o ke kau ʻana. Me ka hana o nā enzyme o nā pēpē e nā lāʻau ʻē aʻe, e hoʻēmi paha kahi hapalua.
2/3 o ka lāʻau lapaʻau e hoʻopili ʻia ma o nā keiki, 1/3 - ma o nā ʻōpū. Hoʻokuʻu piha ʻia ka lāʻau lapaʻau i ke ʻano o nā metabolites.
Nā hōʻailona no ka hoʻohana ʻana
Ke hōʻike nei ka hoʻohana ʻana i kēia pono mea:
- epilepsy (i kuhikuhi ʻia no nā mākaʻi ʻokoʻa a me ka hoʻokaʻawale ʻana a me nā ʻōhumu āpau.
- maʻi bipolar afili;
- maʻiʻo manic psychosis;
- neuralgia trigeminal;
- neuropathy maʻi maʻi, hele pū ʻia e ka ʻeha;
- diabetes insipidus me ka nui o ka diuresis a me polydipsia.
Nā Hoʻohui
Hoʻopili ʻia ka hoʻohana ʻana o Tegretol i kēia mau pilikia:
- ka maʻi kūlohelohe o kēlā me kēia mea ikaika a me nā mea ʻē aʻe o ka lāʻau;
- poloka atrioventricular;
- hali palapala hoʻoweliweli;
- nā kuhi hewa ʻana o ka hana hematopoietic o ka momona o ka iwi;
- Pālani penu palu;
- ka hui pū ʻana o ka lāʻau me nā monoamine oxidase inhibitors.
Pehea e lawe ai iā Tegretol CR
ʻAʻole pili ka ʻai i ka hopena o ka lāʻau lapaʻau. Lawe ʻia ka papa ʻaina a holoi ʻia me ka nui o ka wai e pono ai.
Hiki i ka Monotherapy me Tegretol, me ka hoʻohui pū ʻia me nā mea hana ʻē aʻe.
ʻO ka hoʻoponopono maʻamau no ka hoʻohana ʻana i ka lāʻau e pili ana i ka hoʻokō ʻelua o nā papa o nā papa. Ma muli o nā hopena hopena o ka lāʻau lapaʻau me ka hopena lōʻihi, pono paha ke koi i ka nui o kēlā me kēia lā.
Lawe ʻia ka papa ʻaina a holoi ʻia me ka nui o ka wai e pono ai.
ʻO nā poʻe me ka epilepsy i kono ʻia me ka monotherapy tegretol. Kahi mua ʻia, nā ʻōkuhi liʻiliʻi haʻahaʻa, e hoʻonui ana i ka maʻamau. ʻO ka dosent i hoʻomaka ʻia e ka lāʻau no 100 mg 1 a i 2 mau manawa paha i ka lā. ʻO ka hōʻano maikaʻi loa ʻo ka 400 mg 2-3 mau manawa i kahi lā. I kekahi mau hihia, makemake paha ʻoe e hoʻonui i kēlā me kēia lā i 2000 mg.
Me ka neuralgia n. trigeminus o ka pākōkē mua o nā lā a hiki i ka 400 mg. E hoʻonui hou aʻe i 600-800 mg. Loaʻa i nā poʻe maʻi nā 200 mg o ka lāʻau lapaʻau i kēlā me kēia lā.
ʻO ka poʻe me ka hoʻoneʻe ʻawaʻawa ua kuhikuhi ʻia mai 600 a 1200 mg / lā. Ma nā hopena hōʻemi hōʻemi nui, ua hui pū ʻia ka lāʻau me nā lāʻau lapaʻau sedative.
ʻO nā mea maʻi me ka maʻi manic psychosis e kuhikuhi ʻia mai 400 a 1600 mg o Tegretol i kēlā me kēia lā. Hoʻomaka ka lāʻau lapaʻau me nā haʻahaʻa haʻahaʻa, a laila e hoʻonui iki.
Me ka maʻi diabetes
Hōʻike ʻia ka Carbamazepine no nā maʻi me ka neuropathy maʻi maʻi. Hoʻomaʻa ʻia ka lāʻau lapaʻau i ka hōʻeha e hōʻeha i ka hopena o ka hopena o ka metabolic i nā kiko nīnū. ʻO ka dosage i kēlā me kēia lā i ʻōlelo ʻia no ka neuropathy diabetes maʻi he 400 i ka 800 mg.
Hōʻike ʻia ka Carbamazepine no nā maʻi me ka neuropathy maʻi maʻi.
Nā hopena hopena o Tegretol CR
Ma ka ʻāpana o ka io o ka hihiʻo
Hiki:
- nā hana ʻino i ka ʻono ʻana;
- hui kūlohelohe;
- tinnitus;
- hypo-hyperacusia;
- ʻōpua o nā kīʻaha.
Mai ka musculoskeletal a me ka hoʻopili pili
Hiki i nā hopena ʻae loa aʻe:
- ʻāʻā naʻau
- ʻāwili eha.
ʻŌpala Gastrointestinal
Hiki ke ola ʻia o ia ʻano kūlike:
- ninini
- utuka
- ka mumū o nā ʻili o ka waha;
- ke hoʻololi ʻana i ke ʻano o ka noho;
- maʻi hana maʻi palakeke;
- hoʻololi i ka pae o ka hana o nā kinohi ati.
Hematopoietic mau hui
Hiki iā lākou ke pane i ka lapaʻau me ke ʻano o:
- leukopenia;
- thrombocytopenia;
- agranulocytosis;
- anemia
- hōʻemi i nā pae waikawa folic.
Hiki i nā organ Hematopoietic ke pane i ka mālama ʻana me thrombocytopenia.
Pūnaehana pīhoihoi waena
Hiki i ʻĀina e pane i nā maʻi me nā ʻano ʻino pili ʻole i kēia:
- ʻʻAla
- poʻomanaʻo
- maʻiila neuropathy;
- paresis;
- haunaele ʻōlelo;
- nāwaliwali o ke kino;
- hiamoe
- hallucinatory syndrome;
- hoʻonui ulu irritability;
- nā maʻi kaumaha;
- ʻike wua
- nā maʻi hana;
- nā maʻi kūlike;
- mea momona.
Hiki i ka ʻōnaehana sentral pokole ke pane aku i ka therapy me ka ʻike pālua.
Mai ka pūnaehana urinary
Nānā ʻia:
- jade;
- pollakiuria;
- mālama urinary.
Mai ka papa huhū
Hiki i nā hanana:
- ʻaʻano pōkole
- wahi maʻi pneumonia.
Ma ka ʻāpana o ka ʻili
Nānā ʻia:
- haaheo;
- dermatitis;
- huu
- erythema;
- Hoʻolimalima;
- nā mākaʻi;
- rashes;
- hipogekisisis.
Mai ka pūnaehana genitourinary
Hiki paha ke kala ʻole.
Mai ka pūnaehana genitourinary, hiki ʻole ke kala ʻole.
Mai ka pūnaehana cardiovascular
Hiki:
- poloka atrioventricular;
- arrhythmia;
- ua emi ka nui o ka naʻau;
- ka ulu ʻana o nā hōʻailona o ka maʻi ʻeha coronary.
ʻŌnaehana Endocrine
Hiki paha ke ʻano:
- kuolo;
- kekahikecia;
- ʻōpolipolia;
- hypothyroidism.
Mai ka ʻaoʻao o ka metabolism
Hiki:
- hyponatremia;
- hoʻokiʻekiʻe ʻia
- hoʻonui i ka kolamu.
Allergies
Hiki paha ke ʻano:
- hopena pane;
- lymphadenopathy;
- fiva
- angioedema;
- meningitis aseptic.
Mai ka lawe ʻana i ka Tegretol CR ma ka hopena, hiki i ka mea maʻi ke nānā i ke kuni.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
Hiki i nā hana e pili ai i ka hana me ka piʻi ʻana o ka nānā nui e mālama ʻia i ka wā e lawe ana i ka carbamazepine. ʻO kēia ma muli o ka hiki o nā hopena ʻona mai ka ʻōnaehana o ka pīpī.
Nā ʻōlelo kikoʻī
Hoʻohana i ka wā kahiko
I kekahi mau hihia, pono ke koi ʻia kahi hoʻoponopono i kēlā me kēia lā.
Koha i na keiki
Hiki ke kuhikuhi ʻia ka lāʻau lapaʻau no nā keiki. ʻO ka dosage i kēlā me kēia lā mai ka 200-1000 mg, e hilinaʻi ana i ka makahiki a me ke kaumaha o ka mea maʻi. I ke koho ʻana i ka lāʻau lapaʻau, hāʻawi ʻia nā keiki ma lalo o 3 mau makahiki e koho i kahi lāʻau lapaʻau i ke ʻano o kahi ʻōmaʻomaʻo.
Hoʻohana i ka wā hāpai a me ka lactation
ʻO ka ʻoihana me ka caramazepine i ka wā hapai e lawe ʻia me ka makaʻala nui loa. Hoʻomaopopo i ka ʻoiaʻiʻo hiki ke hoʻonui i ka tegretol i ka hōʻemi o ka vitamin B12 i nā wahine hāpai.
Ke mālama nei i ka wai kahu hānai me ka carbamazepine, pono ia e hoʻololi i ke keiki i ke kīlohelo. Hiki i ka hānai hoʻomau me ka mālama mau ʻana i ka pediatrician. Inā ulu kahi keiki i kahi ʻano ʻino, pono e hoʻolale ʻia ka hānai.
Ke noi no ka hana renal haukapole
Pono ke kuhikuhi iā Tagretol ma hope o ka loiloi ʻana i ka hana ʻeha. ʻAʻole ia e noʻonoʻo i ka hoʻohana ʻana i ka lāʻau lapaʻau i nā mea maʻi me ka maʻi renal koʻikoʻi.
Pono ke kuhikuhi iā Tagretol ma hope o ka loiloi ʻana i ka hana ʻeha.
Hoʻohana no ka hana lawelawe lēwa
ʻO ka moʻolelo o ka maʻi pāpaʻi he kumu no ka mālama ʻana i ka wā e lawe ai i ka lāʻau. ʻO ka nānā ʻana i ka hana o ka ate he mea pono hoʻi e pale i ka hoʻomōhuli ʻana o nā maʻi o ka pā hepatobiliary.
Ka palena o ka Tegretol CR
Ma muli o kahi overdose o ka carbamazepine, hele mai nā hōʻailona pathological ma ka ʻaoʻao o ka nupepa, nā mea hanu a me nā hana puʻuwai. Pukaʻi aʻe, ʻike anuria, pale ākea pū kekahi.
Hoʻopau ʻia nā hōʻailona overdose e ka holoi ʻana i ka ʻōpū a me ka hoʻohana ʻana i nā ʻōpū. Pono e mālama ʻia ka lāʻau lapaʻau i loko o ka haukapila. Hoʻomaopopo ʻia ka maʻi Symptomatic, ka nānā ʻana o ka hana cardiac.
Hoʻopili pū me nā lāʻau ʻē aʻe
Ke hui pū nei ʻo Tegretol me nā mea hana'ē aʻe e hoʻololi i ka pae o ka hana o ka isoenzyme CYP3A4, ka paʻa o ka carbamazepine i nā kahe koko. Hiki paha kēia i kahi hōʻemi o ka hoʻomaʻamaʻa maikaʻi. ʻO kēlā mau hui pū ʻana o nā lāʻau lapaʻau e koi paha i ka hoʻoponopono hoʻoponopono ʻia.
E hōʻemi i ka paneʻana o ka waiwai hana me ka phenobarbital.
ʻO Macrolides, azoles, histamine receptor blockers, nā lāʻau lapaʻau no ka hoʻomehana retroviral hiki ke hoʻonui i ka hoʻoili ʻana o ka waiwai ikaika i ke kahe koko.
E hui pū me nā phenobarbital, valproic acid, rifampicin, felbamate, clonazepam, theophylline, etc., e hōʻemi i ka kahe o ka mea hana.
ʻO ka hoʻoponopono like ʻana o kekahi mau lāʻau lapaʻau e pono ai ke hoʻoponopono hou ʻana i kā lākou hewa: tricyclic antidepressants, corticosteroids, protease inhibitors, calcium channel blockers, estrogens, antiviral agents, antifungal drug.
ʻO ka hui pū me kekahi diuretics alakaʻi i kahi emi o ke kaila o ka sodium. Hiki i ka Carbamazepine ke hōʻemi i ka hopena o nā hopena me nā hoʻomaha hoʻomaha non-polarizing.
Hiki i ke hoʻohana me nā wīwī i waha e hiki ai i ke kahe koko.
Hoʻolaha ka waipuna
ʻAʻole ia e hāʻawi ʻia e hoʻopau i kekahi ʻano kīmino i ka wā o ka Tegretol.
Nā kuʻina
ʻO nā ʻano kuʻina o kēia hāmeʻa nā:
- Finlepsin Retard;
- Finlepsin;
- Carbamazepine.
ʻO kekahi o nā meaʻala o ka lāʻau lapaʻau ʻo Finlepsin Retard.
ʻO nā ʻokoʻa ma waena o Tegretol a me Tegretol CR
Heʻokoʻa kēia lāʻau lapaʻau mai ka Tegretol maʻamau i ka manawa hoʻokuʻu o ka carbamazepine. He hopena lōʻihi nā papa.
Waihue huaʻōlelo waiho nā huaʻōlelo
Kauka lāʻau ʻāpono.
Hiki iaʻu ke kūʻai me ke kī ʻole
ʻAʻohe.
Kūʻai
E hilinaʻi ma ka wahi o ke kūʻai.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Pono e mālama i kahi ma kahi maloʻo i kahi wela ʻaʻole eʻoi aku ma mua o + 25 ° C.
ʻO ka lā kau
Kūpono i nā kūlana i mālama ai, 3 mau makahiki mai ka wā o ka pā.
Mea hana
Hoʻohana ʻia ka lāʻau lapaʻau e Novartis Pharma.
Hoike Mai
Artem, 32 makahiki, Kislovodsk
ʻO ka Tegretol kahi lāʻau lapaʻau maikaʻi e kōkua ana i ka hoʻokele waiwai. Hoʻomaka e lawe i kēia lāʻau, ua loaʻa hou iaʻu ka manawa e ola ai i kahi ola maʻamau. Hoʻopā nā papa ma nā liʻiliʻi a me nā mākana liʻiliʻi. ʻAʻole au i ʻike i nā hopena ʻaoʻao i ka wā o ke noi ʻana. Ke kuhikuhi nei wau i nā mea a pau i loaʻa i ka maʻi epilepsy.
Nina, 45 makahiki, Moscow
Ua hoʻohana i kēia pono i ka makahiki i hala. ʻO nā lāʻau antiepileptic kahiko i lilo i addictive, ua kauka ke kauka ʻo Tegretol ma kahi pono. Ua inu wau i nā papa no 2 mau pule. A laila ua ʻike ʻia nā ʻōpiopio. Hōʻike ʻia ka maʻi a me ka luaʻi Ua kaumaha koʻu olakino, hopohopo au i ka maʻi kaumaha. Pono au e hele hou i ke kauka. Ua hana ʻo ia i nā hoʻoili. ʻO ka lāʻau lapaʻau i hoʻokau i nā hopena hematological: hoʻomohala ʻia ka anemia a me thrombocytopenia. Pono wau e hoʻololi wikiwiki i ka lāʻau.
Cyril, 28 makahiki, Kursk
Ua kuhikuhi ke kauka i kēia lāʻau lapaʻau i ka hui pū me nā mea ʻē aʻe no ka mālama ʻana i nā neuralgia trigeminal. ʻAʻole wau i ʻike inā ua kōkua ʻo Tegretol a i nā lāʻau lapaʻau ʻē aʻe, akā ua nalowale nā hōʻailona. Hoʻomaka nui mai nā hōʻeha o ka ʻeha. Eia hou ua hiki iaʻu ke hiamoe a ʻai maʻamau. Hiki iaʻu ke hāpai i kēia lāʻau lapaʻau i nā mea i kū i nā pilikia like.