ʻO Glimecomb kahi māmeni hypoglycemic i ke koi ma ka type 2 diabetes mellitus. Mālama i ka lāʻau lapaʻau i ka hopena o ka momona o ka momona o ka metabolism, e hōʻemi i ka hopena o nā pli atherosclerotic ma nā pā vascular, hoʻoemi i ke kaumaha o ke kino i ka momona. Ua kuhikuhi ʻia ka lāʻau lapaʻau i ka nalo ʻole o ka hopena o nā meaʻai a me ka hoʻomaʻamaʻa.
Inoa Kūʻai ʻole honua
ʻO Glyclazide + Metformin.
ʻO Glimecomb kahi māmeni hypoglycemic i ke koi ma ka type 2 diabetes mellitus.
ATX
A10BD02.
E hoʻokuʻu i nā palapala a me ka ʻano
ʻO ka lāʻau lapaʻau i hana ʻia ma ke ʻano o nā papa keʻokeʻo no ka hoʻohana ʻana i ka waha, i hōʻike ʻia e ka pona melemele a i ʻole ke kāʻei a me kahi ʻano laulā-cylindrical. Hoʻohui ka lāʻau lapaʻau me 2 mau pūhui kaha: 40 mg o gliclazide a me 500 mg o ka metformin hydrochloride. ʻO Povidone, magnesium stearate, sorbitol a me ka sodium croscarmellose sodium e like me nā mea kōkua. Aia nā papa i loko o nā waihona 10 i nā pūʻulu blister. I loko o kahi kāleka kāleka he 6 blisters.
Ka hana lāʻau lapaʻau
ʻO ka lāʻau lapaʻau e pili ana i nā hui hoʻohui hypoglycemic no ka hoʻoponopono waha. ʻO ka lāʻau lapaʻau ka hopena o ka pancreatic a me ka extrapancreatic hopena.
ʻO Glyclazide kahi derobe o ka sulfonylurea. Kālana ka hana o ka hana o kahi pūlea kemika e pili ana i ka hoʻoulu ʻana o ka hana pilikino i nā peka beta pancreatic. Ma muli o ka hopena o ka hypoglycemic hopena, ʻo ka hiki ke hoʻonui i nā cell body i ke insulin, e hoʻonui ka hoʻonui i ka hormone. Hoʻihoʻi ka mea ola i ka hana mua o nā mokupuni o Langerhans a pōkole i ka manawa mai ka manawa o ka ʻai ʻana a hiki i ka hilo ʻana o ka insulin.
Hoʻokumu ʻo Glimecomb i ka hoʻoluhi ʻana i ke kaupaona ʻana ma hope o ka ʻai ʻana i ka meaʻai ma ka hope o ka momona.
Hoʻopili i ke komo ʻana i ka protein metabolism, ʻoi aku ka mea lapaʻau e hoʻomaikaʻi i ka microcirculation capillary, e hoʻemi ana i ka hōʻuluʻulu ʻana o platelet, a laila e pale ana i ka hoʻomohala ʻana o ka vomb trombosis. E pale aku i ke ʻano o ke lawe ʻana iā Glimecomb, hoʻōla maoli ka uku o ka pā vascular, ua pani ʻia ka microthrombosis a me ka atherosclerosis, a hoʻihoʻi ʻia ka fakaninolysis parietal maoli. ʻO ka lāʻau lapaʻau ka hana kūlohelohe o ka pane vascular i hoʻonui ʻia i ka adrenaline i microangiopathies. Hoʻopau i nā lilo momona i ka wā e hele ana i ka papaʻai ma ka ʻaoʻao o ka momona.
ʻO Metformin hydrochloride kahi pūʻulu biguanide. ʻO ka hoʻohui pūʻana e hoʻemi i ka hoʻoliʻi plasma o ke kō ma ke kīpē i ka gluconeogenesis i nā hepatocytes a me ka hoʻēmi ʻana i ka helu o ka hoʻoliʻi glucose i loko o ka pākuhi liʻiliʻi. Lawe ka lāʻau i ka hana ma lipid metabolism, hoʻohaʻahaʻa i ka pae o lipoproteins low low, triglycerides a me cholesterol i ke koko. Kōkua ia i ka hoʻemi ʻana i ke kaumaha o ke kino, akā i ka hiki ʻole o ka insulin i ka serum, ʻaʻole i loaʻa ka hopena therapeutic. I ka wā e noiʻi ai i nā kauka, ʻaʻole i hōʻike ʻia nā hopena hypoglycemic.
Lapaʻau lāʻau
Gliclazide | Metformin |
Me ka hoʻokele waha, ʻike ʻia kahi kiʻekiʻe kiʻekiʻe o ka absorption. Ke hoʻohana nei i ka 40 mg, ʻo ka nui o ka ʻike ʻana i kahi mea i loko o ka plasma i hoʻoponopono ʻia ma hope o 2-3 mau hola. He kiʻekiʻe ka kamaʻilio ʻana me nā protein plasma - 85-97%. Ma muli o ka hoʻokumu ʻana i nā mea paʻakikī o ka protein, ua hoʻoili koke ʻia ka lāʻau i nā kiko āpau. Hana ia i ka loli i loko o nā hepatocytes. ʻO ka hoʻopauʻana hapa-ola e hana i nā hola 8-20. Hoʻopau ʻia ka mea hana i ka urine e 70%, me nā mea maʻi he 12%. | Hoʻopili kokeʻia e ka microvilli i loko o kahi pākī liʻiliʻi ma ka 48-52%. ʻO ka bioavailability inā lawe ʻia ma kahi ʻōpū ʻole he 50-60%. Loaʻa ka ʻike kiʻekiʻe piha i nā hola 1-2 ma hope o ka hoʻokele ʻana. He haʻahaʻa ka paʻa ʻana i ka protein protein. Hoʻomaopopo ʻia ka nui o ke kōpulu ʻana. ʻO ka hapalua-ola kahi 6.2 hola. Hoʻopili ʻia ka lāʻau lapaʻau ma o nā keiki i loko o kā lākou ʻano mua a me 30% ma o nā ʻāpana. |
Hoʻohana ʻia ka lāʻau lapaʻau e mālama i nā maʻi maʻi type 2.
Nā hōʻailona no ka hoʻohana ʻana
Hoʻohana ʻia ka lāʻau lapaʻau e mālama i nā maʻi maʻi type 2, i ka wā e liʻiliʻi ai ka mālamaʻana i ka mālama ʻana i ka meaʻai, ka hana kino a me ka lāʻau lapaʻau me ka Metformin a me Gliclazide.
Hoʻohana ʻia kahi mākoki hypoglycemic i mea hoʻopiʻi no ka mālamaʻana i nā lāʻau lapaʻau me ka 2 mau mea kanu i ka poʻe maʻi me ka mellitus non-insulin-hilinaʻi, ʻoiai ke mālama pono ka glucose koko.
Nā Hoʻohui
ʻAʻole kōkua ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana ma kēia mau hihia.
- maʻi mellitus type 1;
- lactic acidosis;
- ka pae ʻai pāpaʻi plasma kiʻekiʻe;
- coma maʻiʻai, precoma;
- diabetes ketoacidosis;
- hana kaʻeha kaumaha i loko o nā pūpū a me nā maʻi e hoʻonāukiuki i ka hana o nā huina (dehydration, infectious me nā hōʻeha hopena, hoʻoluhi);
- porphyria;
- lawe ʻana i ka miconazole;
- hele hewa hewa hana;
- weliweli cardiogenic, ka pōloli oxygen, ʻāwaliwali o ka ea, ka holo ʻana o myocardial;
- huaʻalo pōkole, hoʻihoʻi i nā hōʻailona;
- nā kūlana e pono ai ka inika insulin (nā hōʻeha post-traumatic, hana hoʻoponopono hou ma hope o ka nui o ka hōʻeha ʻana, kuni ʻia);
- emi mai ma mua o 48 mau hola a i loko o 2 mau lā ma hope o ka radiography e hoʻohana ana i ka hoʻohālikelike iodine;
- nā haʻahaʻa-kalona haʻahaʻa a i ka wā i lawe ʻia ai ma mua o 1000 kcal i ka lā;
- hypersensitivity o ke kino o ka mea maʻi i nā ʻāpana o ka lāʻau.
Eia kekahi, ʻaʻole ia e hāʻawi ʻia i ka lāʻau lapaʻau no ka poʻeʻelemakule e hana nei i nā kūlana o ka hoʻoikaika kino kino, ma muli o ka hiki ke hoʻomohala ʻia o ka lactic acidosis.
Pono e mālama ʻia i ka mālama ʻana i ka maʻi o ka maʻi, ka hana ʻana o ke kelepona adrenal, hana ʻole ʻana i nā pituitary anterior, nā iʻa thyroid.
Pehea e lawe ai i ka glimecomb
ʻO ka lāʻau e manaʻo ʻia no ka hoʻokele waha ma ka wā ʻai a i ʻole hoʻi ma hope o ka ʻaina. Hoʻoholo ʻia ka nui o ka hoʻoponopono ʻia a me ka lōʻihi o ka mālama ʻana e ke kauka, e kau ana i kahi hoʻohālike lāʻau ʻōiwi i kau ʻia i ka kahe o ke kō i loko o ke koko.
Me ka maʻi diabetes
ʻO kahi maʻi hoʻokahi i ka hoʻomaka mua o ka hana maʻi ʻo 540 mg o nā papa me ke neʻe o ka hoʻokele i kēlā me kēia lā a hiki i 1-3 mau wā. I ka nui o nā manawa, lawe ʻia ka lāʻau lapaʻau i 2 mau manawa i ka lā - i ke kakahiaka a ma mua o ka moe. Koho ʻia ka helu o kēlā me kēia lā a hiki i ka uku mau ʻana o ke kaʻina pili.
Nā hopena hopena o ka glimecomb
Hoʻokumu nā hopena maikaʻiʻole i ke kino o ka mea maʻi me ka hoʻokele kūpono ʻole o ka lāʻau a i ʻole hoʻi i ke kua o nā maʻi kūloko.
ʻO ka lāʻau e manaʻo ʻia no ka hoʻokele waha ma ka wā ʻai a i ʻole hoʻi ma hope o ka ʻaina.
ʻŌpala Gastrointestinal
Loaʻa nā hopena ʻaoʻao i ka ʻōnaehana digestive e like me:
- dyspepsia, kahi hana kaomi;
- mau manaʻo kaumaha o ka ʻōpū;
- naki, holo
- eha epigastric;
- ke ʻano o ke ʻano o ka ʻala ma ke kumu o ke alelo;
- hoʻemi i ka momona.
I nā pilikia pinepine, hoʻonui i ka hana o ka hepatocytic aminotransferases, hoʻonui ʻia ka phosphatase alkaline. ʻOi paha ka hoʻomohala ʻana o ka hyperbilirubinemia a hiki i ka hōʻea ʻana o ka jaundice cholestatic, koi i ka hoʻokuʻu ʻana o ka lāʻau.
Hematopoietic mau hui
Hiki i ka lāʻau lapaʻau ke hana i ka pale ʻana i ka hana o ka ʻōpū o ka iwi ʻulaʻula, ma muli o ke ʻano o ka helu ʻana o nā ʻōnaehana koko ʻano, ua hoʻonui ʻia ka agranulocytosis, hemolytic anemia.
Pūnaehana pīhoihoi waena
Mahalo paha i ka emi ʻana o ke koikoi o ka ʻike, nā ʻeha.
Mai ka pūnaehana cardiovascular
ʻO Arrhythmia, sensation o ke kahe koko.
ʻŌnaehana Endocrine
Inā ʻaʻole i hahai ʻia ke kaukēpē o nā dose a ʻaʻole i ukali ʻia ka meaʻai, hoʻonui ʻia ka pilikia o ka hypoglycemia, i ukali ʻia me ka nāwaliwali koʻikoʻi, mau ke ea neʻe hou ʻana o ka pilikia, hoʻonui nui ʻia, nā kau ʻana o ka naʻau, nā haunaele a me ka hoʻomohala ʻana.
Mai ka ʻaoʻao o ka metabolism
E kūʻē i ke kūleʻa o ka maʻi metabolic, hiki mai paha nā lactic acidosis. Hoʻohālikelike ka kaʻina pathological e ka nāwaliwali, nā ʻoi loa o ka hōʻeha ma nā ʻōpū, ke kaumaha ʻana o ka ʻōpū, ka ʻeha i loko o ka ʻōpū, kahi hōʻemi i ke ana a me ke kahe o ke koko, a me ka bradycardia.
Allergies
Hōʻike ka anaphylactoid i nā derivatives sulfonylurea i hōʻike ʻia i ke ʻano o ka vasculitis allergic, urticaria, macula, ʻū a me ka pruritus, ka edema Quincke, ka pīhoihoi anaphylactic.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
I ka wā o ka mālama ʻana me Glimecomb, pono pono e mālama i ka mālama ʻana i ka wā e holo nei, ka hana me nā ʻenehana paʻakikī a me nā hana ʻē aʻe e koi ai i ka hoʻokaumaha mai ka mea maʻi.
Nā ʻōlelo kikoʻī
Ke lawe nei i nā derivatives sulfonylurea, aia kahi hopena o ka hoʻouluʻana i ka hypoglycemia koʻikoʻi a lohi, pono ia i ka mālama kūikawā i nā kūlana o ka hana a me ka hoʻokele ʻana o ka hoʻomālamalama wai 5% no 4-5 mau lā.
Hoʻopilikia ka pilikia o ka hoʻomohala ʻana i nā patula me ka lawa ʻole o kaʻai ʻana i ka meaʻai, ka hana kino lōʻihi a i ʻole ka hoʻomalu ʻana i kekahi mau lāʻau hypoglycemic. No ka hoʻēmi ʻana i ka pilikia o ke kaʻina pili, pono e kākau pono i nā ʻōmole o nā ʻōkuhi i hoʻopili ʻia i ka lāʻau lapaʻau a loaʻa nā ʻike holoʻokoʻa i ka wā o ka kūkākūkā me ke kauka komo.
Pono ʻia ka hoʻoponopono ʻana no ka hoʻonaninua ʻana a me ke ʻano a me nā loli i ka meaʻai.
Hoʻohana i ka wā kahiko
ʻAʻole pono ka poʻe i ʻoi aku o 60 mau makahiki i ka lāʻau ma mua o ka hana kino kino ma muli o ka hoʻonui nui o ka waikika lactic.
Koha i na keiki
ʻAʻole ʻia ka lāʻau lapaʻau e lawe ʻia a hiki i ka makahiki 18.
ʻAʻole ʻia ka lāʻau lapaʻau e lawe ʻia a hiki i ka makahiki 18.
Hoʻohana i ka wā hāpai a me ka lactation
Ke ulu mai ka wā hānai, pono e hoʻololi ʻia ke alakaʻi ʻana i ka Glimecomb me ka hoʻomehana ʻana o ka insulin, no ka mea hiki ke ʻōkuhi ʻo nā mea ikaika i nā mea ikaika ma o ka leʻa placental. ʻAʻohe ʻikepili i ka hopena teratogenic o nā mea hoʻohui ʻelua.
Hiki ke hoʻopili ʻia ʻo Glyclazide a me ka metformin i loko o ka waiū makuahine, no laila, i ka wā o ka mālama ʻana me ka ʻaihue hypoglycemic, pono ke hoʻopau ʻia ka lactation.
Ke noi no ka hana renal haukapole
Hoʻokomo ʻia ka lāʻau i ka hihia o nā hana o ke akepaʻa a me ka nephropathy maʻi.
Hoʻohana no ka hana lawelawe lēwa
Ke papa ʻia nei ka lāʻau lapaʻau me ka hana maikaʻi o ke ake.
Ka overlimose Glimecomb
Me ka hōʻinoʻole o ka lāʻau lapaʻau, ulu lactic acidosis a me kahi kūlana o ka hypoglycemia e ulu. Inā aia nā hōʻailona o ka hālaʻi lactic acid o nā lau, pono kāhea koke ʻoe i kahi ambulance no ka mea nona ka ʻōpala. I nā kūlana hoʻomehana, holomua ka hemodialysis.
I ka hihia o ka nalowale o ka ʻike, kahi infra intravenous o kahi hopena o ka hopena o 40% e pono ai ka intramuscularly a iʻa subcutaneously.
I ka hihia o ka nalowale o ka hoʻomaopopo ʻana, pono ka infravenous infusion o kahi hopena o ka hopena 40% glucose, glucagon, intramuscularly a iʻa subcutaneously, pono nō. Ma hope o ka hoʻokau ʻana, pono ka mea maʻi i nā meaʻai momona.
Hoʻopili pū me nā lāʻau ʻē aʻe
Ke lawe ʻia nā lāʻau lapaʻau e like me Glimecomb, ʻike ʻia nā hopena like ʻole:
- Ke hoʻoikaika nei i ka hopena therapeutic i hui pū me nā captopril, antenaagulants Coumarin, beta-blockers, bromocriptine, antifungal agents, salicylates, fibrates, MAO inhibitors, tetracycline antibiotics, non-steroidal anti-inflammatory drugs and anti-tuberculosis.
- ʻO Glucocorticosteroids, barbiturates, nā lāʻau antiepileptic, ka mea hoʻomalu a me ka calcium tubule, thiazide, diuretics, Terbutaline, Glucagon, Morphine e hāʻawi i ka hoʻemi i ka hana hypoglycemic.
- Hoʻonui ka Cardiac glycosides i ka leʻalā o ka ventricular extrasystole, aʻo ke kāohi ʻana i ka hematopoiesis pumehana o nā iwi, hoʻonui i ka pilikia o ka myelosuppression.
ʻO ka lāʻau lapaʻau ka hōʻemi o ka plasma plasma o Furosemide e 31% a me kāna hapalua-ola ma ka 42%. Hoʻonui ka Nifedipine i ka helu o ka hoʻopili ʻana o ka metformin.
ʻO ka lāʻau lapaʻau ka hōʻemi o ka plasma plasma o Furosemide e 31% a me kāna hapalua-ola ma ka 42%.
Hoʻolaha ka waipuna
ʻAʻole pāpā ʻia i ka inu ʻawaʻī i ka wā mālama. Hoʻonāukiuki ʻo Ethanol i ka hopena o ka hoʻohālikelike koʻikoʻi a me ka hoʻomohalaʻana i ka waikika lactic. Hoʻonui ka Ethanol i ka hopena o ka uluʻana i ka hypoglycemia.
He aha e pani ai
ʻO nā mea kikoʻī o ka lāʻau lapaʻau, ka like me ka hoʻopiha a me nā mea lae o ka pharmacological, e loaʻa:
- Diabefarm;
- ʻO Glyformin;
- Hoʻolaha iā Gliclazide MV.
Hiki ke loli i kahi lāʻau lapaʻau ʻē aʻe me ka loaʻa o kahi hopena therapeutic mai ka lawe ʻana iā Glimecomb ma lalo o ka mākaʻikaʻi koʻikoʻi o ka mea kauka.
Waihue huaʻōlelo waiho nā huaʻōlelo
Kūʻai ʻia ka lāʻau lapaʻau e ka lāʻau lapaʻau.
Hiki iaʻu ke kūʻai me ke kī ʻole
Hoʻokuʻu ʻia ka kūʻai ʻana aku o ka lāʻau lapaʻau ma muli o ka hoʻonui nui o ka hypoglycemia i ka wā e lawe ai i ka hewa hewa.
Kumukūʻai Glimecomb
ʻO ke kumukūʻai kumukūʻai o nā papa he 567 rubles.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Pono ke mālama i ka lāʻau ma waho o ka hiki ʻana mai o nā keiki, ma kahi maloʻo a me kahi wahi hoʻi i kahi wela ʻaʻole e hoʻonui ʻia + 25 ° C.
ʻO ka lā kau
2 makahiki
Mea hana
La lāʻau a me ka mea kanu lāʻau "AKRIKHIN", Rusia.
Hoʻokuʻu ʻia ka kūʻai ʻana aku o ka lāʻau lapaʻau ma muli o ka hoʻonui nui o ka hypoglycemia i ka wā e lawe ai i ka hewa hewa.
Nā Hōʻike Diabetic no Glimecomb
ʻO Arthur Kovalev, 40 makahiki, ʻo Moscow
No ka maʻi type 2, ua lawe wau i nā papa Glimecomb no hoʻokahi makahiki i hoʻokahi makahiki. ʻAʻole hōʻemi nā paona kino, no ka mea ma hope o ka lawe ʻana i ka lāʻau āu e makemake ai e ʻai. Akā ma hope o koʻu lawe ʻana i ka pōkole ma ke ahiahi ma mua o ka hiamoe, e hoʻomaʻamaʻa ke ʻano. I ke kakahiaka, ʻokoʻa ke kō mai ke kō a 6 a 7.2 ma hope o ka lawe ʻana i ka paila me ka ʻaina kakahiaka.
Kirill Gordeev, 29 makahiki, Kazan
ʻO ka lāʻau maikaʻi e hōʻemi i ke kō koko. ʻAe wau iā 8 mau mahina. Ua kau hoʻi au i nā inikini insulin. Ma hope o ka haunaele ʻana i ka hāʻawi ʻana i ka hormone, pono wau e lawe i kekahi mau pila no kekahi manawa, akā hōʻike lākou i hana ʻoi kiʻekiʻe. Noho ka Sugar i ka pae hoʻokahi, ʻoiai ke hana i nā aʻa hemahema ma kuʻu hihia.
Hōʻike nā kauka i nā kauka
Marina Shevchuk, endocrinologist, 56 makahiki, Astrakhan
Ke hōʻemi ʻia nei ka lāʻau lapaʻau e pili ana i ka mua o ke ʻano maʻi diabetes ʻano 2 no ka glycemia maikaʻi. Hiki i ka hoʻokuʻu i hoʻololi ʻia ke hōʻemi i ka ulu ʻana o ka maʻi hypoglycemic syndrome, ʻo ia ke kumu e hana ai ka poʻe maʻi a me nā poʻe i loaʻa nā maʻi o ka ʻōnaehana cardiovascular e hiki ai i ka lāʻau lapaʻau. Hoʻohana pinepine wau i ka lāʻau lapaʻau i kaʻu hana lapaʻau me kahi koho pākēneka hoʻokahi. ʻO ka kumukūʻai haʻahaʻa me ka hana kiʻekiʻe.
ʻO Evgenia Shishkina, ʻo endocrinologist, 45 makahiki, St.
Loaʻa i ka lāʻau lāʻau ka hopena a me ka maikaʻi. Kōkua ia i ka hoʻohaʻahaʻa i ke kōhi koko. I ka wā o ka mālamaʻana, he mea nui e ukali i ka papaʻai, akā e ʻai maʻamau, ʻo ia hoʻi e hoʻomaʻamaʻa. ʻAʻole mālama ʻia nā hopena e pili ana me ka paʻa pono ʻana i ka regimen dado. Hoʻomaka ka hana a ka lāʻau lapaʻau i kahi manawa pōkole. Ua hoʻokumu ka lāʻau lapaʻau iā ia iho i ka mākeke no ka maʻi diabetes.