ʻO Neurontin kahi hoʻomākaukau e like me ka hoʻolālā spatial i ke GABA neurotransmitter (gamma-aminobutyric acid). I ka mua, ua manaʻo ʻia ʻo ka hana ikaika o ka lāʻau lapaʻau e like me ka anticonvulsant. A he mau makahiki wale nō ma hope iho nei, ua hōʻike ʻia kona kaha pono i ka mālama ʻana i kekahi mau pilikia o ka maʻi ʻehaʻeha o ka maʻi neʻe ʻana o ka maʻi neurogen.
Inoa Kūʻai ʻole honua
INN - Gabapentin.
ʻO Neurontin kahi hoʻomākaukau e like me ka hoʻolālā spatial i ke GABA neurotransmitter (gamma-aminobutyric acid).
ʻO Neurontin ka inoa kālepa i loko o ka Latin.
ATX
ʻO ka helu ATX ʻo N03AX12.
E hoʻokuʻu i nā palapala a me ka ʻano
Hoʻohana ʻia ia i ke ʻano o nā papa a me nā capsules, ʻo ka mea hoʻoikaika i ka gabapentin.
E heluhelu pū e pili ana i nā maʻi ʻē aʻe:
Neurontin 600 - nā ʻōlelo aʻoaʻo no ka hoʻohana.
Neurontin 300 - kahi i ʻōlelo ʻia?
Nā Palaki
ʻO Ellipse-like, i kāwili ʻia me kahi kāahu a me ka kālai ʻana NT. Ma ka ʻaoʻao ʻē aʻe o ka pākaukau, e pili ana i ka pona o ka waihona ikaika, ua kuhi ʻia nā helu.
- ma nā papa me 600 mg gabapentin kiʻi 16;
- 800 mg - 26.
Nā papa hana elliptical i ulana ʻia.
ʻO ka hoʻonohonoho, hoʻohui i nā hana ikaika, loaʻa i nā mea kōkua;
- Poloxamer-407;
- kōpana;
- E572.
Kālai ʻia kā lākou kumukūʻai ma ka paʻa ʻana o ka waihona kumu.
Nā ʻatikā
ʻO nā Capsules e ka helu gabapentin:
- 100 mg
- 300 mg;
- 400 mg
Hoʻoweliweli nā kālena i nā hiʻohiʻona (ka ʻoniʻina o ke kapa gelatin) a me ka hōʻailona.
Kūʻokoʻa lākou i ka helehelena (ka lau o ke kapa o gelatin) a me ke kāpili ʻana. He keʻokeʻo nā hāmeʻa 100 mg, 300 mg melemele ka melemele, a he 400 mg ʻōmaʻomaʻo nā ʻeleʻele. Ma kahi o gabapentin, hoʻopihapiha i nā kapsul:
- waiū paʻuhū kālele;
- kōpana;
- hoʻōla hoʻolima.
Hoʻololi ʻia nā capsules i ka nui - ʻAʻohe 3, 1, 0 i ka ʻōiwi hoʻoweliweli i ka dosage.
Ka hana lāʻau lapaʻau
ʻOiai ke ʻano like o ka hoʻolālā me GABA, ʻaʻole pili ka gabapentin i nā mea hoʻokipa GABAA a me GABAA. Hoʻākāka ʻia nā waiwai analgesic e ka hiki i ka mea e hoʻopaʻa ai i kekahi mau kō o ka puna wai tubule i loaʻa i ka presynaptic pale o nā nerve nerve o nā kuli o nā hua kīwī o ke kīwī.
Inā luku ʻia nā nū mamao (mamao), nui ka nui o nā subun o α2-δ. Hoʻonui kā lākou hāmeʻa i ka kahe o ka Ca2 + i loko o ka pūnaewele i ka membrane, ka mea e hōʻemi ai i kona depolarization a hōʻemi i ka manawa o ka hana. I kēia hihia, hoʻonaninani ʻia ka nui o nā mea waiwai (neurotransmitters) - glutamate a me ka waiwai P - i hoʻokuʻu ʻia a i ʻole synthesized, ionotropic glutamate receptors.
ʻO ka hopena analgesic o Neurontin e pili ana i ka pale ʻana i ka lawe ʻana i nā hōʻailona hōʻeha i ka nui o ke kaula spinal.
Hana wale ʻia ʻo Gabapentin ma luna o nā mea hoʻopiʻi e hoʻāla ʻia, me ka ʻole o ka hoʻopiʻi ʻana i ka transit kalsioma i loko o nā mea hookomo ʻole ʻia. ʻO ka hopena analgesic o Neurontin e pili ana i ka pale ʻana i ka lawe ʻana i nā hōʻailona hōʻeha i ka nui o ke kaula spinal. Eia kekahi, pono ka lāʻau lapaʻau i nā ʻōnaehana ʻē aʻe:
- NMDA nā mea hopu;
- pākia huika;
- pūnaehana opioid;
- ala nā monoaminergic.
Hoʻopili i kahi paʻa o ka hoʻokele spinal, ua hōʻike ʻia kahi hopena supraspinal. Ke hana nei ka lāʻau lapaʻau ma ke alahaka, cerebellum a me ka nuclei vestibular, e wehewehe nei ʻaʻole wale ka hopena analgesic, akā ʻo ka waiwai anticonvulsant, e kāpae nei i ka hoʻohui i nā opioids a i hoʻomohala i ka insensitivity.
No laila, maikaʻi ka lāʻau lapaʻau ʻaʻole wale no ka hoʻopau ʻana i ke kaumaha maʻi, akā no ka hoʻomaha ʻana i ka ʻehaʻeha.
Lapaʻau lāʻau
ʻO ka hopena o ka Neurontin e hilinaʻi ana i ka dosis. Ma hope o ka lawelawe waha ʻana o 300 a me 600 mg o kahi ukana, ʻo kona emi ʻana he 60% a me 40%, pākahi, a me ka hōʻemi me ka hoʻonui nui ʻana. Pili ka lāʻau lapaʻau me ka liʻiliʻi liʻiliʻi me nā protein plasma (3-5%). ʻO ka nui o ka hoʻoili ʻana ʻo ~ 0.6-0.8 l / kg. Ma hope o ka lawe iā 300 mg o ka gabapentin, hiki i ke kiko kiʻekiʻe (2.7 μg / ml) o ke koko koko ma hope o nā hola 2-3.
Pili ka lāʻau lapaʻau me ka liʻiliʻi liʻiliʻi me nā protein plasma (3-5%).
Ke hele koke nei ʻo Gabapentin i ka pale koko-lolo. ʻO kāna hana i ka waiahi cerebrospinal he 5-35% o nā plasma, a i loko o ka lolo - a hiki i 80%. Ma ke kino, ʻaʻole ke kahili ʻia ka waiwai i ka biotransformation a hoʻopio ʻia e nā keiki i loli ʻole. Aia ka palena o ka excretion i ka clearance hana (ʻo ka nui o ke koko plasma i hoʻoneʻe ʻia mai ka creatinine i 1 mau minuke). I ka poʻe maʻi me ka hana renal maʻamau, ʻo ka hapalua o ke ola o ka mea ma hope o hoʻokahi pahu he 4.7-8.7 mau hola.
He aha ka mea e kōkua ai?
Hāʻawi i ka hoʻomaha o ka maʻi a me ka maʻi paleha me:
- maʻi maʻi rheumatic;
- postherpetic neuralgia;
- ka mumū o ka nerve trigeminal;
- maʻi pāʻaiʻi a me ka polyneuropathy hana;
- nā ʻeha hōʻehaʻeha discogenic maʻi me ka osteochondrosis, radiculopathy;
- carpal tunnel syndrome;
- hoʻonui i ka mākaukau spasmodic o ka lolo;
- ʻiliʻilielia;
- tiga hōʻeha.
Ke lawe nei iā Neurontin, ʻaʻole wale ka hōʻeha ʻana o ka maʻi neuropathic. Hoʻohana ʻia ka lāʻau no ka analgesia prophylactic ma mua o kahi hana paʻakikī a paʻakikī. Ke kōkua nei ka hoʻokomoʻana e hōʻemi i ka nui o nā anesthetics i hoʻohana i ka wā postoperative, a me ka hōʻemi nui loa i ka nui o ke kaumaha.
ʻAʻole hiki i ka lāʻau lapaʻau ke ho'ōki wale i ka hana mua (pololei i ka mahele o ke keʻena hana) ka maʻi postoperative, akā pili pū kekahi i ka lua (kahi mamao mai ke kahua hoʻokele) ʻeha ma muli o ka hana pilikino ma ka kiko.
Hoʻohana ʻia ka lāʻau lapaʻau no ka epilepsy i mea he anticonvulsant. I ke ʻano o kahi lāʻau lapaʻau i hana ʻia e hoʻomaha ai i kahi ʻāpana māhele.
Nā Hoʻohui
ʻO nā hoʻohālikelike i ka hoʻohana ʻana iā Neurontin:
- pīhoihoi i ka hui ʻana;
- makahiki a hiki i 3 mau makahiki.
ʻO kahi contraindication i ka hoʻohana ʻana o Neurontin heʻano maʻamau ia i nā maʻi kūlohelohe.
Me ka mālama pono
ʻO nā maʻi me ka pilikia ʻole e pono ke kuhikuhi i ka lāʻau lapaʻau me ka mālama ʻana ma lalo o ka kaohi o ka hana hana. No ka mea e hoʻopau ʻia i ka wā hemodialysis, pono ke hoʻoponopono ʻia.
Pehea e lawe ai i ka neurontin?
Lawe ʻia ka lāʻau lapaʻau me ka ʻōlelo maʻamau, holoi ʻia me ka wai, me ka manaʻo o ka meaʻai. Hiki iā ʻoe ke hoʻokaʻawale i ka papa ma ka hapalua, e uhai ana i ka hopena. Hoʻopau ʻia ka mālama ʻia ma ka hoʻomaka mua ʻana e like me kēia ʻanoʻano penei.
- 1 ka lā - 300 mg hoʻokahi lā i ka lā;
- Lā 2 - 300 mg 2 mau manawa i kahi lā;
- Kiʻi 3 - 300 mg 3 mau lā i ka lā.
Hōʻike ʻia kēia ʻano hana i nā mea maʻi a me nā wā'ōpiopio mai nā makahiki 12. Inā makemake ʻia ka hōʻaila ʻana no ka lāʻau, a laila lawe ʻia ia, e hoʻohaʻahaʻa i ka nui no nā lā 7, a me kahi hōʻailona ʻole.
Lawe ʻia ka lāʻau lapaʻau me ka ʻōlelo maʻamau, holoi ʻia me ka wai, me ka manaʻo o ka meaʻai.
I kekahi mau hihia, hiki i nā mea maʻi pākiki ke hoʻomaka i ka mālama ʻana me kahi kaona o 900 mg me ka hoʻonui liʻiliʻi (titration) o 300 mg i kēlā me kēia lā 2-3 mau lā. ʻO ka lōʻihi loa o kēlā me kēia lā he 3600 mg. Aia nō i 3 wiki. I loko o kahi kūlana koʻikoʻi o ka mea maʻi, hoʻonui ka nui i ka nui ma nā puʻu liʻiliʻi a i ʻole nā wahi ākea ma waena o ka huakaʻi.
No ka mālamaʻana i ka epilepsy, pono e hoʻohana mau ʻia ka lāʻau lapaʻau. I kēia hihia, ke helu ʻia nei ka helu o kēlā me kēia lā e ke kauka.
Lawe i ka lāʻau lapaʻau no ka maʻi maʻi maʻi
Hoʻohana ia e like me ka lāʻau koho ke koho no ka hōʻoluʻolu o ke kaumaha ma ka polyneuropathy diabetes. Hoʻomaopopo ʻia e kuhikuhi i ka lāʻau lapaʻau ma 300 mg i kēlā me kēia lā i ke ahiahi, e neʻe lohi (i kēlā me kēia 2-3 mau lā) e hoʻonui i ka lāʻau i ka 1800 mg i kēlā me kēia lā.
Hoʻohana ia e like me ka lāʻau koho ke koho no ka hōʻoluʻolu o ke kaumaha ma ka polyneuropathy diabetes.
Pehea e hiki ai iaʻu ke lawe?
Pono ʻia ka lāʻau e lawe ʻia ʻaʻole eʻoi aku ma mua o 5 mau mahina, no ka mea ʻaʻole i aʻo ʻia kahi papa hana lōʻihi loa. Me kahi lōʻihi lōʻihi, kaupaona ka loea i ka pono no ka hōʻike lōʻihi.
Nā hopena ʻaoʻao o Neurotin
Hoʻohana pinepine ʻia, ma waena o nā hopena ʻaoʻao o ka lawe ʻana i ka lāʻau lapaʻau, dizziness a me ka sedation ʻē aʻe. ʻOi aku ka liʻiliʻi, ua loaʻa ka hopena i ka hopena i nā ʻōnaehana like ʻole.
ʻŌpala Gastrointestinal
Hoʻomaopopo pinepine ʻia:
- nā kuʻikahi o nā neʻe ʻana;
- ka maloʻo ʻana o ka oropharynx;
- ka hana piha hau;
- hemo wale, he luaa
- ʻeha nā huapuni;
- maʻi ōwā;
- mea pono ʻole o ka makemake.
I ka wā hope-therapeutic, ua hōʻike ʻia nā hihia o ka pale ʻana o ka maʻi pancreatitis.
Hematopoietic mau hui
Loaʻa pinepine ka leukopenia, hypertension arterial a luhi thrombocytopenia.
Pūnaehana pīhoihoi waena
Hōʻike pinepine ʻia:
- hiamoe
- pūnana;
- nāwaliwali
- paresthesia;
- hāpau
- hoʻomanaʻo hoʻomanaʻo
- ka nānāʻole o ka naʻau;
- ka ʻauhau ʻana o nā pahuhopu.
Maikaʻi pinepine ka lāʻau lapaʻau e alakaʻi i ka nalowale o ka ʻike, nā mea noʻonoʻo pono ʻole, e like me ka huhū, phobias, hopohopo, i lilo i ka hala ʻole o ka noʻonoʻo.
Mai ka pūnaehana urinary
ʻO nā hihia i hoʻonāukiuki ʻia o ka pākuʻi ʻana, ʻoi aku ka maikaʻi o ka pale. Hoʻokomo ʻia nā lehelehe maʻi, me ke komo pū ʻana o ka urinary tract, ʻike pinepine ʻia.
Mai ka ʻōnaehana musculoskeletal
Hoʻohui pinepine, e launa pū me ka:
- myalgia;
- aopala;
- hooweliweli a ʻōiwi.
Ma ka ʻāpana o ka ʻili
Aia pinepine nā hopena kūlike i ke ʻano o:
- puʻuwai;
- lakui;
- huehue
- rashes;
- huu.
Ma muli o Alopecia, ʻulaʻula, a me kahi lāʻau lapaʻau ka mea maʻamau.
Allergies
Hōʻike ʻia nā ʻōlima e nā pathologies ʻili, he nānā pinepine ʻole ʻia ka pīhoihoi anaphylactic.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
Ke lawe nei i ka lāʻau lapaʻau, ʻaʻohe pono e kaomi i nā kaʻa a hana paha me nā mea koʻikoʻi pōʻino ma mua o kona hoʻokumu ʻia ʻana ʻaʻohe hopena maikaʻi o ka lāʻau i ka hopena neuromuscular.
Nā ʻōlelo kikoʻī
ʻO nā mea maʻi e lawe ana i ka lāʻau lapaʻau i hōʻike ʻia i nā manawa o ka lawaiʻa. No laila, pono pono e nānā i ke kūlana psycho-emosional o nā mea maʻi me ka koho e hoʻoponopono ʻana i nā mea e kū ai.
Inā hōʻike ʻia nā hōʻailona o ka pancreatitis maʻa, ua kau ʻia ka hoʻoholo no ka hoʻokuʻu ʻana i ka lāʻau.
Me ka hoʻoneʻe ʻana o ka lāʻau lapaʻau i ka wā e mālama ai i ka epilepsy, hiki i nā hoʻopaʻi.
Me ka hoʻoneʻe ʻana o ka lāʻau lapaʻau i ka wā e mālama ai i ka epilepsy, hiki i nā hoʻopaʻi. Manaʻo ʻia ka lāʻau lapaʻau he mea ʻole i ka mālama ʻana i nā ʻano koikoi maʻamau a hiki ke alakaʻi iā lākou i ko lākou hoʻoikaika. No laila, e kuhikuhi i kēia lāʻau lapaʻau i nā poʻe maʻi me nā paroxysms i hui pū me ka makaʻala.
Me ka hoʻokolohua ʻōhumu o nā opioids a me Neurontin, hiki i ke kaumaha a CNS ke ulu nei - pono ka nānā ʻana i ke kūlana o ka mea maʻi a me ka hoʻoponopono ʻana i ka manawa kūpono e pono ai.
Hoʻohana i ka wā hāpai a me ka lactation
Hoʻomaopopo ʻia ka lāʻau mālama i ka wā o ka gestation i ka wā i lanakila ai nā pōmaikaʻi ma luna o ka hopena o ka hōʻeha ʻana i ka ʻōpū. ʻAʻohe pono e kāohi i ka hana o ka lāʻau lapaʻau i nā kaila koko.
No ka mea Loaʻa ka lāʻau lapaʻau i ka mea huna o ka keli mammary, i ka wā e hānai ai, pono ia e hōʻoki i ka ʻai maoli o ka pēpē a hoʻoneʻe i ka ʻano.
Hoʻomaopopo ʻia ka lāʻau mālama i ka wā o ka gestation i ka wā i lanakila ai nā pōmaikaʻi ma luna o ka hopena o ka hōʻeha ʻana i ka ʻōpū.
Koho ʻana iā Neurontin i nā keiki
ʻAʻole i kuhikuhi ʻia ka lāʻau me Neurontin a hiki i 3 mau makahiki. I nā makahiki 3-12 mau makahiki, ʻo ka hoʻomaka hoʻomaka ʻana he 10-15 mg / lā. Ua mahele ʻia i 3 doses. No ka hoʻokō ʻana i kahi hopena therapeutic, e hoʻonui pinepine ʻia ia, hiki i ka 40 mg / lā. Pono e hoʻokō pono i kahi mahele o ka hola 12 i waena o nā hopena.
Hoʻohana i ka wā kahiko
I ka hui o nā makahiki kahiko (> 65 mau makahiki), ʻo ka hopohopo o ka hana excretory ma muli o nā kaʻina pili e pili ana i ka nui o nā makahiki, ua loaʻa pinepine, no laila, i nā mea maʻi, e pono ai ka mana o ka cleince clearance.
ʻO ka pale ʻana o ka neurotin
Me ka hoʻokele hoʻokahi o ka maʻi kiʻekiʻe, ʻike ʻia nā hōʻike hou aʻe:
- ʻike ʻole i ka nānā;
- ke kaumaha o ka maikaʻi;
- dyspemia (hoʻokaumaha hana);
- hypersomnia (ka manawa hiamoe);
- makehewa;
- nā kuʻi ʻana i nā neʻe o ka bowel.
Inā nui aʻe ka nui o ka ʻai, inā pū me ke ʻano me Neurontin a me nā mea hoʻohana neurotropic ʻē aʻe, hiki i kahi coma ke ulu.
Ma kahi laina kiʻekiʻe, nā injections kūpono a me ka hoʻomaʻemaʻe koko extrarenal i hōʻike pinepine ʻia i nā mea maʻi me ka renal dysfunction.
Hoʻopili pū me nā lāʻau ʻē aʻe
Ke hoʻohana ʻia nei ʻo Neurontin me ka derivatives opium poppy, hiki ke hoʻomaopopo i nā hōʻailona o ka hoʻokau ʻana o CNS. ʻO nā loli i loko o nā lāʻau lapaʻau o Neurontin i ka wā e lawe ai i ka lāʻau antiepileptic i ʻike ʻole ʻia.
ʻO ka hui pūʻana o nā lāʻau lapaʻau a me nā antacids e hoʻemi ana i ka hoʻoneʻe ʻana o Neurotin e kahi 1/4.
Hoʻohui ʻia ʻo Venoruton a me nā venotonics ʻē aʻe me ka mea ikaika o ka lāʻau a hiki ke kuhikuhi ʻia e pale i ka hopena maikaʻi ʻole mai ka ʻōnaehana kaʻai ʻana.
Me kahi hōʻike maʻalahi e pili ana i ka hopena alerine, nā antihistamines, e like me Cetrin, i hoʻohana pono ʻia me ka lāʻau.
Me kahi hōʻike maʻalahi e pili ana i ka hopena alerine, nā antihistamines, e like me Cetrin, i hoʻohana pono ʻia me ka lāʻau.
Hoʻolaha ka waipuna
ʻAʻole koi ʻia e inu i ka waiʻona a me ka lāʻau lapaʻau i ka manawa like, no ka mea nā hopena ʻelua i ka pūnaehana sentral. Eia nō naʻe, hoʻohana ʻia ka lāʻau lapaʻau i ka mālama ʻana i ka hilinaʻi i ka waiʻona. Hoʻemi ia i nā kuko no ka waiʻona, e hoʻoneʻe i ka insomnia a me ke kaumaha.
Nā kuʻina
Aia kekahi mau hōʻailona like no Neurotin:
- Convalis;
- Kūleʻa;
- Egipentin;
- Gabalept;
- Wimpat;
- Gabastadine
- Tebantin;
- Gabapentin;
- Katena.
Waihue huaʻōlelo waiho nā huaʻōlelo
Ma ke kumu.
Hiki iaʻu ke kūʻai me ka loaʻa ʻole o ka hōʻailona?
ʻAʻole kōkua ʻia ka lāʻau lapaʻau hou-mai-ka-pale e pale aku i ka hoʻopunipuni.
Uila no Neurontin
ʻO ke kumu he 962-1729 mau rubles.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Store ma kahi wela i ʻole 25 ° C, ma waho o ka hiki ʻana o nā keiki.
ʻAʻole ʻōlelo nā lāʻau lapaʻau hou e loea i ka hoʻopunipuni.
ʻO ka lā kau
ʻAʻole iʻoi aku i 2 mau makahiki.
Mea hana
Pfizer (Kelemānia).
ʻLelo a Neurontin
Alexey Yuryevich, 53 makahiki, Kaluga: "Ua hoʻomaka wau i ka maʻi neuropathic he lōʻihi loa. No ka makahiki hoʻokahi, ua kau ke kauka i ka hoʻokipa ʻana iā Neurontin 300. I ka manawa mua ua maikaʻi ka hopena, akā i kēia wā ua palupalu wau. Hoʻomau wau e lawe i ka lāʻau, akā ke hopohopo nei wau no ka lōʻihi o ka mālama ʻana. aole i oi aku ka pomaikai. "
Konstantin, 38 makahiki, Odessa: 'Ua kuhikuhi ke kauka i ke ala o Neurontin.I loko nō o kēia manawa, ʻaʻohe hopena hopena i makaʻu ʻia, a maikaʻi maikaʻi ka lāʻau lapaʻau. "
ʻO Olga, 42 makahiki, ʻo Melitopol: "Ma hope o ka lawe ʻana iā Neurontin, ua hoʻomau ka hopena, ʻaʻole wau i nā manawa palupalu, ʻaʻole ʻeha koʻu mau wāwae.
