Hiki i ke kolamu ke kiʻekiʻe i ke koko ke alakaʻi i nā kūlana kūlohelohe. Me ka hyperglycemia, pilikia ke ʻano o ka cardiovascular, ʻike ʻia ka atherosclerosis, a me nā pāpaʻi momona i kau ʻia ma nā ʻalopiha a me nā ona.
Ke hoʻohalahala ʻia ke kīʻaha koko, e piʻo ke kahe o ke koko a kū ka hypoxia. Hiki i kēia ke alakaʻi i ka hoʻouka o ka naʻau, ka puʻupuʻu, a me ka thrombosis. Loaʻa pinepine kēia i ka make.
Hoʻopuka ākea i ka hoʻomohala ʻana i ka atherosclerosis i nā maʻi maʻi maʻi, ka mea, e kū'ē i ka ʻala o ka hyperglycemia, hoʻopau ʻia ke kino holoʻokoʻa. No laila, pono lākou e nānā pono i ko lākou olakino a ʻaʻole i ʻae i ka kolokala ʻino e hōʻiliʻili i ke koko.
I kēia lā, ʻo nā mea lāʻau lapaʻau e hāʻawi i kahi nui o ka kolamu e hoʻohaʻahaʻa i nā mea lāʻau. ʻO kekahi o nā lāʻau maikaʻi loa ka simvastol. Akā ma mua o ka lawe ʻana i ka lāʻau lapaʻau, pono ʻoe e hoʻomaʻamaʻa iā ʻoe iho i nā ʻōlelo no ka lāʻau lapaʻau a nīnau aku i kahi kauka.
ʻO ka hana Pharmacological, hoʻonohonoho a me nā puka o ka hoʻokuʻu
Hoʻopiliʻo Simvastol i ka hana o ka cholesterol a pale i ka hana o ka hoʻoneʻe o ka huina o ka hana o ka mevalonate. Hoʻemi kēia mau mea i ka hoʻoneʻe ʻana o nā triglycerides, haʻahaʻa haʻahaʻa a kiʻekiʻe i nā lipoproteins kiʻekiʻe ma loko o ke koko.
He hopena kumumana ke lāʻau lapaʻau, no laila e ʻike ʻia kona hopena ma hope o 14 mau lā o ka hoʻohana ʻana. Hoʻopili koke ʻia ʻo Simvastol i loko o ke kahawai, ua hoʻokō ʻo ka nui o ka nui o ka minuke 120 mau minuke ma hope o kona hoʻoponopono.
I loko o ka puʻuwai, e loli ka lāʻau lapaʻau, ka hopena i ka hoʻomohala ʻana i nā waikena beta-hydroxyl, nona ka hopena kākāmeka ikaika. ʻO ka hoʻopauʻana hapa-hapalua o nā metabolites he 2 mau hola. Holo lākou i ke kino ma o nā ʻōpū.
ʻO ka māhele nui o ka simvastol ka simvastatin. Loaʻa ʻia kēia puʻu ma o ka hoʻomalima ʻana o ka ʻanā mauʻa ʻo Aspergillus terreus.
Nā kumuwaiwai hou o ka lāʻau lapaʻau.
- macrogol;
- citric acid a me ka lactose monohydrate;
- hao keʻa;
- kekoex
- magnesium stearate;
- hao keʻa;
- titanium carbon a pēlā aku.
Loaʻa ka lāʻau lapaʻau i kahi palapala papa. ʻO ka pahu hoʻokahi he 14 a 28 mau papa. I loko o kahi pahu polūʻeleʻele he 10 mg, ma ka melemele - 20 mg, ma ke brown - 40 mg o ka waiwai ikaika.
Nā hōʻailona a me nā contraindications
Hoʻomaopopo ʻia ka hoʻohana ʻana o ka simvastatin no ka hypercholesterolemia primus type IIa a i IIb me ka hoʻonui nui aʻe o ka hoʻomohala ʻana i ka atherosclerosis me ka like ʻole o ka hanaʻai a me ka hoʻomaʻamaʻa ʻai ʻana. Eia kekahi, hiki i ka lāʻau lapaʻau ke kōkua me ka ischemia cardiac me kahi mea e pale aku ai i ka loaʻa ʻana o ka maʻa, hōʻeha ka naʻau.
Ua kuhikuhi ʻia ʻo Simvastol no ka cholesterol kiʻekiʻe, i hui pū ʻia me hypertriglyceridemia. Hoʻomaopopo ʻia ka lāʻau lapaʻau i ka wā o ka hoʻomākaukau no ka revascularization i mea e hōʻemi ai i ka hopena o nā hoʻopiʻi.
ʻO nā hoʻohālikelike i ka hoʻohana ʻana i ka simvastatin - maʻi maʻi, myopathy, ke kāohi ʻole ʻana i nā mea o ka lāʻau. ʻAʻole kuhikuhi ʻia ka lāʻau lapaʻau i kona wā ʻōpiopio a me kona wā ʻōpio.
Me ka mālama aka, hoʻohana ʻia ka simvastol i nā ʻalaki penei:
- maʻi ōpū;
- waiʻona wai;
- haunaele o ka pae wai-electrolyte;
- ke koko haʻahaʻa;
- nā hōʻeha
- pilikia ʻole;
- Hoʻōla ʻia o nā ʻūhā o ke kāwili;
- nā hopena endocrine;
- maʻi ʻino loa;
- nā hāʻule ʻole i ka hana kaʻina metabolic;
- hapai ka hepatitis B
Eia kekahi, ʻaʻole pono e lawe i nā papa ma hope o nā kaʻina hana. I keʻano pilikino, ua contraindicated ka lāʻau i ka hoʻololi ʻana i nā kino o loko i ka wā e hoʻohana ʻia nā immunosuppressants.
Nā ʻōkuhi no ka hoʻohana ʻana i nā papa
Ke hōʻike nei ka manual no ka hoʻohana ʻana i ka lāʻau lapaʻau ka ʻona ʻia hoʻokahi manawa i ka lā i ke ahiahi, holoi ʻia me ka wai. Eia nō kekahi, ʻo ka manawa lawe ʻana iā Simvastol, ʻaʻole pono e pili me ka hoʻohana ʻana i ka meaʻai.
Ma mua o ka hoʻomaka a i ka wā o ka hoʻolaʻa, pono e hoʻopili ʻia kahi meaʻai anticholesterol. I ka hoʻomaka mua o ka mālama ʻana, e hoʻolako ʻia e inu i nā papa i loko o kahi waihona o 10 a me 20 mg.
Wahi a ka koʻikoʻi o ka hypercholesterolemia, hiki i ke kauka ke hoʻololi i ka nui o nā mea ikaika mai 10 a 80 mau lā i kēlā me kēia lā. Inā pono, i kēlā me kēia 28 mau lā e hoʻoponopono ke kauka i ka dosis. I ka hapa o nā mea maʻi, hiki i ka hopena therapeutic kiʻekiʻe loa i ka loaʻa ʻana o 20 mg o Simvastol i kēlā me kēia lā.
Me ka hypercholesterolemia hoʻoilina (homozygous), ka nui o kēlā me kēia lā o ka lāʻau lapaʻau he 40 mg / lā a i ʻole 80 mg i kēlā lā, i hoʻokaʻawale ʻia i ʻekolu mauʻu (20/20/40 mg).
Me ka maʻi naʻau coronary, ʻo ka nui i manaʻo ʻia ʻo 20-40 mg i kēlā me kēia lā. Inā emi mai ka ʻike o LDL ma mua o 1.94 mmol / L, a me ke kiʻekiʻe o ka cholesrol āpau he 3.6 mmol / L, a laila hoʻemi ka lāʻauʻala.
I nā maʻi pēpē maʻi, ke lawe nei i nā fibrates, ka momona nicotinic a me Simvastol, ʻo ka nui o ka ʻōlelo i hoʻolilo ʻia i kēlā me kēia lā ʻaʻole loa ma mua o 10 milligrams.
ʻO nā maʻi e inu iā Amiodarone a i Verapamil e lawe iā Simvastol i loko o kahi nui a 20 mg i ka lā.
Nā hopena ʻaoʻao a me nā kamaʻilio lāʻau
I ka wā e mālama ai me Simvastol, hiki i kahi nui o nā hopena maikaʻiʻole ke hoʻomohala. No laila, ma hope o ka lawe ʻana i ka lāʻau lapaʻau, hoʻāla pinepine ka huina o ke kino, ka mea i hōʻike ʻia e ka ʻōpala, constipation, bloating, pancreatitis, nausea, hepatitis.
ʻO kekahi manawa pili ka hopena ʻaoʻao i ka ʻōnaehana musculoskeletal. ʻO ka hopena o kēia mea he mau ʻūʻā uaua, myalgia, malaise, myopathy, rhabdomyolysis.
I ka wā o ka hoʻohana ʻana i ka simvastatin, hiki ke hōʻike ʻia nā maʻi like, e like me ka urticaria, polymyalgia, lupus, ʻā, vasculitis, angioedema, rheumatoid arthritis, pōkole o ka hanu. Hiki ke hoʻoulu hou i nā hopena dermatological - hyperemia a me ka hoʻonāukiuki i ka ʻili, dermatomyositis, photosensitivity, alopecia.
Hiki i ka hoʻohana ʻana o simvastol i hiki ke hoʻopilikia i ka hana ʻana o ka wahī:
- hoʻowahāwahā ʻaʻa;
- lie kanikela
- maʻiila neuropathy;
- ʻthenlelo hemolele;
- ka ʻike maka ʻana i ka maʻi diabetes;
- ʻōpala
- nā wahī pilipila;
- aloha.
ʻO nā hopena maikaʻi loa e kū mai ma hope o ka lawe ʻana iā Simvastol me ka hoʻokaʻawale ʻana i ka potency, ʻoi aku ka hoʻomaʻamaʻa ʻana o ka renal, anemia, wela wela, a me ka puʻuwai wikiwiki. Hiki i ka Simvastatin ke hoʻopilikia i nā ʻāpana kauka, i hōʻike ʻia e thrombocytopenia, kahi piʻi i loko o ESR, eosinophilia.
E pili ana i nā hoʻopili ʻana i ka lāʻau lapaʻau, pono ia ʻike i ka lāʻau lapaʻau e hoʻonui i ka hopena o nā anticoagulants, e hoʻonui ai i ka hopena o ke kahe. Hoʻonui ka hopena therapeutic o Simvastol me kāna hui pū me ka wai ʻona.
Inā ʻoe e lawe i nā papa me Verapamil, cytostatics, Erythromycin, nicotinic acid, Amiodarone, antifungal agents, Diltiazem, HIV protease inhibitors, Telithromycin, Clarithromycin, a laila piʻi nui ka hopena.
ʻO ka helu, nā loiloi a me nā kumukūʻai
Nui nā lāʻau lapaʻau i hana ma ke kumu o simvastatin. No laila, hiki iā ʻoe ke kahakaha iā Simvastol me kēia mau ʻano - Simgal, Ariescor, Zovatin, Levomir, Zokor, Simvor, Actalipid.
ʻO kahi analogue kaulana o Simvastol ʻo Avestatin. ʻO kekahi mea e hoʻoneʻe hou ʻia ʻo Vasilip. Nui kekahi mau lāʻau lapaʻau i kapa ʻia he mau mea hoʻoikaika ʻia.
Ke loaʻa nei kēia mau lāʻau iā Simvastatin Alkaloid / Vero / SZ / Teva / Pfizer / Chaikafarm / Ferein. Nā mea hoʻohālikelike a me nā mea e pili ana i ka lāʻau lapaʻau Simvastol - Simvakol, Zorstat, Simlo, Sinkard, Aterostat.
Loaʻa iā Simvastatin ka loiloi maikaʻi. ʻO kēia ma muli o ka hopena kiʻekiʻe o ka lāʻau lapaʻau a me ka palena liʻiliʻi e ulu i ka hopena maikaʻiʻole.
Eia naʻe, ʻike nā poʻe e lawe nei i nā papa e pili ana i ka simvostatin e hiki i kahi lāʻau lapaʻau ke hoʻohaʻahaʻa i ka kolesterol kino ʻino ma o 20%. ʻO ke koena LDL e lawe ʻia i ke kino ma o ka lāʻauʻai.
Ua hōʻike kekahi mau maʻi e kōkua ana ʻo Simvastol iā lākou e pale aku i ka ʻaina. A ma hope o ʻeono mau papa o ka mālama ʻana, ua hoʻomaikaʻi maikaʻi ke ʻano o nā ʻuhane a me nā puʻuwai koko, i hōʻoia ʻia e nā hoʻokolohua hōʻike.
Aia ke kumukūʻai o ka lāʻau lapaʻau ma muli o kona iniha. No laila, ʻo Simvastol No. 28 10 mg mau kumukūʻai e pili ana iā 187-210 mau rubles, a me Simvastol 20 mg - a hiki i 330 rubles.
Pehea e hoʻohaʻahaʻa ai i ka cholesterol i ke koko e haʻi i ka loea i ke wikiō ma kēia ʻatikala.
