ʻO nā pā kiʻi Metformin 1000 mg he oval a convex ma nā ʻaoʻao ʻelua.
ʻO ke ʻano ʻapoʻala o kahi ʻāpana o ka lāʻau lapaʻau he lei keʻokeʻo.
ʻO kahi mahele o ka lāʻau Metformin 1000, ʻo ka mea hoʻomohala ikaika o ka metformin hydrochloride. Aia kēia pūpū he 1000 milligrams no kēlā me kēia papa.
Hoʻopiliʻia i kahi pāʻana o 1000 mg, kahi lāʻau lapaʻau e loaʻa ana i kahi dosis o 850 a me 500 mg ka huahana e ka lāʻau lapaʻau.
Hoʻohui ʻia i ka nui o ka pūnao kemika kumu, loaʻa i kēlā me kēia papa pākuʻina o nā pūhui kūlohelohe e hoʻokō ai i nā hana kōkua.
ʻO nā mea kemika e hana i nā hana kōkua?
- mikulamulamina selulose;
- sosa ʻo ke pākeke laupili;
- wai maʻemaʻe;
- povidone;
- paʻahau magnesium.
Aia ka lāʻau i ka pūʻulu o nā lāʻau lapaʻau haʻahaʻa e hoʻohana ʻia a ma ke ʻano o ka mālama ʻana i ka maʻi maʻi. ʻO ka lāʻau e manaʻo ai e mālama i ke kō koko, hoʻohana ʻia ma ke ʻano. ʻO kēia pūhui kaha e pili ana i nā ʻōhulu nunui.
Hiki ke kūʻai ʻia ka lāʻau lapaʻau ma kekahi keʻena lāʻau lapaʻau ma luna o ka lāʻau lapaʻau. Ke waiho nei ka hapa nui o nā mea maʻi e pili ana i nā loiloi maikaʻi e pili ana i ka lāʻau, ʻo ia ka mea e hōʻike ai i ka hopena kiʻekiʻe o ka lāʻau lapaʻau.
Loaʻa ka Metformin ozone i kahi kumukūʻai 1000 mg ma Lūkini, kahi e kūlike ai mai ka māhele o ke kūʻai aku ma ka Russian Lūkini a me nā awelika mai 193 a 220 mau rubles i kēlā me kēia pālua.
Pharmacological waiwai o ka lāʻau
Ma hope o ka hoʻohana ʻana i ka wai kūpono o ka lāʻau, ua hoʻopili ʻia ka metformin mai ka ʻeha o ka gastrointestinal. ʻO ka lāʻau mai ke lumen o ka pēpē gastrointestinal e hoʻopili piha ʻia. ʻO ka bioavailability o ka lāʻau e pili ana i ka 50-60%. Loaʻa ka ʻike kūpono loa i ke kino ma hope o 2-2,5 mau hola ma hope o ka lawe ʻana i ka lāʻau.
Me ka pao like ʻole o ka meaʻai a me ka lāʻau lapaʻau, ke emi ʻana o ka hoʻoulu ʻana o ka mea hana i ka nui o ka haʻalulu a kū i ka manawa.
Ke komo i loko o ka plasma koko, ʻaʻole i pili ka metformin hydrochloride i ka hoʻopili ʻana me nā protein plasma a ʻaʻole hana paʻa i nā pūhui paʻakikī.
Hoʻopili iki ʻia nā metformin a hoʻopili ʻia e nā keiki.
ʻO ka hapalua o ka ola o ka lāʻau lapaʻau e kū nei i loko o nā hola 6.5.
Inā paʻa kahi mea maʻi me ka maʻi mellitus o ka huehue o ka pale, nui ka hapalua hapalua ola a loaʻa ke ola ʻana i ke kaʻina o kahi hana cumulation i loko o ke kino.
Ke hoʻohana nei i ka lāʻau lapaʻau e hiki ai iā ʻoe ke hōʻemi i ka hyperglycemia i ke kino o ka mea maʻi, me ka hoʻonāukiuki ʻole ʻana i nā ʻōuli o nā hōʻailona o ka hypoglycemia. ʻAʻole pili ka lāʻau lapaʻau i ka synthesis o nā insulin e nā cell beta o ka pancreatic tissue. ʻAʻole hoʻonā ka lāʻau lapaʻau i ka hoʻokumu ʻana o kahi kūlana hypoglycemic i nā poʻe olakino
ʻO ka hoʻohana ʻana o ka Metformin ozone hiki ke hoʻonui i ka manaʻo ʻana o nā membrane cell i loko o nā cell-dependant insulin peripheral i insulin, ua hāʻawi i ka hoʻonui o ka nui o ka glucose i hoʻohana ʻia e nā cell.
Hiki i ka metformin hydrochloride ke pale i nā kaʻina o ka gluconeogenesis e hele ana i loko o nā puna o ka puna o ka ate a kau i ke kahe o ka glucose mai ka lumen o ka ʻeha gastrointestinal.
ʻO ka hopena o ka hana ikaika o ka lāʻau lapaʻau ma ka glycogen synthetase e alakaʻi i ka hoʻonui i ke kaʻina o ka synthesis glycogen. Ma o kā kāna hana ʻana i nā membrane cell, hoʻonui i ka metformin ka nui o nā ʻano kīʻaha o ke kaʻa ʻana i nā mea hoʻoweliweli.
Pākuʻi ʻana i ka hana ikaika i loko o ke kino e alakaʻi i ka hopena maikaʻi ma ka lipid metabolism, e hana ana i ka emi o ka kolamu ma ke kino.
Loaʻa ka ʻike o Metformin i ka hoʻohālikelike o ke kaumaha o ke kino, hiki iā ia ke kūleʻa a hoʻoemi paha i nā pae i ʻae ʻia.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
ʻO ke kumu no ka hoʻohana ʻana i ka lāʻau lapaʻau ka ʻike ʻana i ka diabetes mellitus type 2 i loko o kahi kanaka, i ka hōʻole ʻana o nā hoʻololi maikaʻi i ka dinamics o nā hoʻololi i ke kō o ka honi ma o ka ʻike ʻana i ka mea maʻi i ka mālama ʻana i ka lāʻau lapaʻau a me nā hoʻomaʻamaʻa kino dosed. Kūpono maoli nō kēia no ka poʻe momona nui.
Hiki ke hoʻohana ʻia nā papa i ka mālama ʻana i nā pākeke ma ke ʻano o ka monotherapy a i ʻole hui pū me nā lāʻau lapaʻau hypoglycemic waha a i ʻole ka hana like-insulin.
Hiki ke hoʻohana ʻia ka Metformin 1000 i ka mālamaʻana i ka maʻi diabetes i nā keiki ma luna o 10 mau makahiki he 10, e like me ka mea he mea monotherapeutic a i hui pū ʻia me nā inikini insulin.
Ke lawe ʻia nei ka lāʻau lapaʻau, pono ʻia nā papa make me ka ʻole o ka minamina, aʻo ka lawe ʻana i ka lāʻau e pono pū me ka inu nui o ka wai. Pono e hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau i mua ma mua a i ka wā ʻaina.
Ke hoʻohana ʻia nei ka lāʻau lapaʻau i nā pākeke i ka wā o ka mono a i ʻole ka hōʻola ʻana, pono nā hua ʻōlelo aʻe.
- Pono ka dosis ma mua o ka lāʻau lapaʻau e pono ma mua o 500 mg 2-3 mau manawa i ka lā. I ka wā e hiki mai ana, inā pono, hiki ke hoʻoponopono ʻia i ka nui o ka lāʻau lapaʻau. ʻO ka make ʻana o ka lāʻau lapaʻau i lawe ʻia ʻia ma luna o ke kiʻekiʻe o nā kao i loko o ke koko koko o kahi kanaka e hōʻeha nei i ka maʻi maʻi.
- ʻO ka mālama mālamaʻana o ka lāʻau i ka 1500-2000 mg i ka lā. No ka hoʻēmi ʻana i nā hopena o nā hopena ʻaoʻao i ke kino, e kuhikuhi ʻia ka nui o ka lā i kēlā me kēia lā i nā 2-3. ʻO ka nui loa no ka lā ma 3000 mg i kēlā me kēia lā. Pono e ʻokaʻī ka nui o ka nui ma ka dosis 2-3 i kēlā me kēia lā.
- Kuhi ʻia ka Metformin 1000 no nā poʻe maʻi e loaʻa iā ia kekahi lāʻau lapaʻau i kēlā me kēia lā mai ka 2000-3000 mg i kēlā me kēia lā.
Ke hoʻololi nei e lawe i ka Metformin 1000, pono ʻoe e hōʻole i ka lawe i nā lāʻau lapaʻau hypoglycemic ʻē aʻe.
Nā hiʻohiʻona a me nā hopena ʻaoʻao
E like me nā lāʻau lapaʻau ʻē aʻe, aia ʻo Metformin i kekahi mau contraindications no ke hoʻohana ʻana.
Eia kekahi, i ke koho ʻana i kahi lāʻau lapaʻau, pono ka manaʻo o kekahi e ʻoluʻolu e hōʻoluʻolu ke kanaka i nā hopena ʻaoʻao mai ka lāʻau lapaʻau.
Ma mua o ka hoʻomaka ʻana e hoʻohana i ka lāʻau lapaʻau e like me ke ʻano he lāʻau lapaʻau, pono ʻoe e kamaʻilio me ka endocrinologist.
ʻO nā contraindications e hoʻohana ʻia no ka hoʻohana ʻana:
- ka heleʻana o ka hypersensitivity i ka metformin hydrochloride a i nā mea kōkua;
- ka heleʻana o nā hōʻailona o ka hoʻomohala ʻana o ka ketoacidosis maʻi;
- nā maʻi e hoʻopilikia ai i ka hana o nā keiki maʻi, ka loaʻa ʻana o nā maʻi maʻi pūpū;
- nā ʻano ʻano like ʻole e hoʻonāukiuki i ka loaʻa ʻana o ka pololi oxygen hāwau i ke kino o ke kanaka maʻi;
- hana i nā mea hoʻoponopono ma ke ʻano o ka hoʻohana ʻana i ka lāʻau insulin;
- nā hana ʻino i ka hana maʻamau o ka ate;
- ka hele ʻana o nā maʻi ʻeha a i ʻole ke ʻano ʻawaʻawa make ʻole;
- lactic acidosis;
- ka manawa o ka hanu intrauterine a me ka manawa o ka lactation;
- hoʻomanawanui a hiki i 10 mau makahiki.
ʻO nā hopena nui i ka wā e hoʻohana ai me Metformin, ʻo ia ke ʻano o nā pilikia o ka huehuei ʻana, ka mea i hōʻike ʻia e ka loʻi, nausea a me ka maʻi diabetes, a me kahi hoʻohaʻahaʻa. Ma ka ʻili, hiki i ke kuʻe a me ka hōʻeha. Inā loaʻa nā pilikia i ka puʻuwai, lilo ka hoʻomohala ʻana o ka hepatitis ma hope o ka pau ʻana o ka lāʻau lapaʻau.
ʻO ka ʻike hou aku e pili ana i ka lāʻau lapaʻau Metformin i wehewehe ʻia i ke wikiō ma kēia ʻatikala.
