ʻO Iosuavia kekahi o nā lāʻau lapaʻau maikaʻi loa a palekana loa i hoʻohana ʻia i ka hana lapaʻau e mālama ai i ka maʻi maʻi.
He lāʻau lapaʻau i loko o kona ʻano he lāʻau lapaʻau mai ka pūʻulu o incretins.
ʻO ka incretins lākou iho he mau kamahine e pili pono i ka hoʻopili ʻana i ka insulin a me ka hoʻohana ʻana o ka glucose i loko o ke koko.
ʻO nā hopena mai kēia hui nā hopena pili i ke kino o ke kanaka:
- hoʻoulu i ka hana o ka insulin hormone e nā hua beta o ka pancreas;
- hoʻokaʻawale i ka hana glucagon e nā cell alpha pancreatic;
- lohi i ke kaʻina o ke kīnā ʻana i ka ʻōpū;
- komo i ka hoʻemi ʻana i ka momona;
Eia kekahi, hoʻopilikia maikaʻi ʻia i ka hana o nā ʻōkuhi a me nā ʻōnaehana.
He aha ka mea hypoglycemic agent?
Ua loaʻa ka kaulana o ka maʻi maʻi lā oviavia ma waena o nā mea lapaʻau a me nā mea maʻi me kēia maʻi.
Ua hōʻike ʻia ka papa kuhikuhi i ka hopena hypoglycemic a nona ka hui o DPP-4 inhibitors.
Hoʻohana ka hoʻohana ʻana i ka lāʻau i ka ulu ʻana o nā kūmole hoʻoikaika a hoʻoulu i kā lākou hana. I ka wā o ka hana maʻamau o ke kino, e hoʻoulu ʻia nā incretins i loko o ka ʻawaʻawa, a ala nui aʻe kā lākou pae ma hope o ka ʻai ʻana.
Ma muli o ka hoʻomohala ʻana o ka maʻi mellitus o ka maʻi mellitus, ke hoʻopiʻi nei hoʻi i loko o ka hana o kēia kaʻina hana, a ma muli o ia mea, hoʻokō nā poʻe loea lapaʻau i ka hoʻihoʻi ʻana ma ka hoʻopiʻi ʻana i nā poʻe maʻi i ka lāʻau o Januvia.
ʻO ka incretins ke kuleana no ka hoʻouluʻana i ka hana o ka insulin e ka pancreas.
ʻO nā o nā hiʻohiʻona hana nui o ka lāʻau lapaʻau e:
- Hoʻemi ka hoʻoliʻiliʻi ʻana o ka hemoglobin glycated.
- ʻO ka haʻalele ʻana i nā hōʻailona o ka hyperglycemia (me ka hoʻokaʻa ʻana o ke kōʻai koko wikiwiki).
- ʻO ke kaohiʻana i ke kaumaha o ke kino.
Loaʻa ka lāʻau lapaʻau i ka puka papa ma ke ʻano o ke kāʻei o ka papa, i nā aʻi ʻulaʻula bula.
ʻO ka mea hana nui no ka sitagliptin (mnn), no ka mea he kōkua kōkua o ka calcium hydrogen phosphate, microcrystalline cellulose, magnesium stearate, croscarmellose a me sodium stearyl fumarate, kahi ʻāpana o ka lāʻau. ʻO ka'āina kahi o Hoavia - Netherlands, ʻoihana kāpena "MERCK SHARP & DOHME".
Nā papa hana me ka hāmeʻa ikaika o sitagliptin, ma ke ʻano he lula nō, ua hoʻohana ʻia ia i nā hihia:
- ma ka mālamaʻana i nā maʻi lapaʻau ma muli o kahi maʻi e like me ka maʻi diabetes mellitus type 2, e hoʻonui ai i ka hopena hypoglycemic i hui pū me nā antagonist a i ʻole nā metformin hydrochloride;
- me ka monotherapy i ka hoʻomohala ʻana o kahi hana like ole o ka insulin o ka diabetes mellitus i hui pū ʻia me nā regimens ole lapaʻau lāʻau - ke mālama ʻana i ka ʻai a me ka hana kino.
Pono e hoʻolilo ʻia o ka maʻi paʻakikī o ka hoʻohana ʻana i nā lāʻau lapaʻau o nā pūʻolo penei:
- Hoʻohana pinepine ʻia ka Sitagliptin i hui pū me ka metformin (Siafor, Glucofage, Formmetin).
- Me nā derivatives sulfonylurea (Diabeton a me Amaryl).
- Me nā lāʻau lapaʻau mai ka hui o thiazolidinediones (Pioglitazole, Rosiglitazone).
ʻO nā papa ʻaʻi o Januvia, ka mea e pili ana i ka sitagliptin, e hili koke ana i ka wa o ko lākou lawe ʻana a hiki i ko lākou kiʻekiʻe plasma kiʻekiʻe ma hope o ʻehā mau hola.
ʻO ke kiʻekiʻe o ka bioavailability pololei loa a he ʻokoʻa ka hapaʻumi hapa.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
Ua hoʻomohala ka lāʻau lapaʻau i nā ala no ka hana ʻana o ka lāʻau lapaʻau me nā ʻano like ʻole o ka nui o nā pūnaehana koʻikoʻi.
ʻO ka hoʻoholo ʻana i nā dosage ka mea kūpono loa no ka mea maʻi e hoʻoholo ʻia e ke kauka hele mai.
Ke lawe ʻia nei ka koho o ke ʻano o ka lāʻau lapaʻau ma hope wale nō o ke ʻano loiloi o ka mea maʻi.
Hōʻike ʻia ka papa papaʻaina ma ka mākeke pharmacological i loko o kēia mauʻano:
- ka lāʻau lapaʻau ka 25 mg o ka mea hana ikaika;
- ʻO ka nui o nā mea ikaika e 50 mg;
- Januvia 100 mg - nā papa me ka nui kiʻekiʻe.
Hōʻike nā palapala no ka hana o Hoavia i ka pono o ka lāʻau lapaʻau me ka hoʻohana ʻana i kēia hana:
- Lawe ʻia nā papa papa me ka nui o ka wai, me ka ʻaina ʻole.
- Pono ka lā maʻamau o ka lāʻau e lilo i hoʻokahi haneli milligrams o ka hana ikaika.
- Inā e poina ʻoe i ka ʻōloe aʻe, mai pāpālua i ka nui o ka make ma ka ʻaoʻao aʻe.
- Inā loaʻaʻole ka mea maʻi i nā pōpoki ma nā ʻano o ka hina o ke kino, pono e hoʻemi ʻia ka dosage i kanalima milligrams. Me nā pilikia hana koʻikoʻi koʻikoʻi, ʻaʻole pono ka nui o ka nui ma mua o ka iwakāluakūmālima mau miligram o ka mea ikaika.
Hoʻohana ʻia ka hoʻohana ʻana o sitagliptin e like me ka kuhikuhi ʻana e kahi lāʻau lapaʻau.
I ka hihia o ka lāʻau overdose, hiki ke ʻike i nā loli o ka mahele QTc. Ma ke ʻano he mālama mālama ʻia, e hoʻohana ʻia nā ʻano lāʻau e like me ka gastage lavage, ka hoʻohana ʻana i nā lāʻau lapaʻau enterosorbent a me ka maʻi hōʻailona.
Nā Hoʻohui
ʻO Iosuavia kahi lāʻau mālama palekana no ka maʻi maʻi.
He ʻano ʻokoʻa kūikawā o ka lāʻau lapaʻau hypoglycemic Januvia mai nā lāʻau lapaʻau haʻahaʻa-hoʻoemi hou ia ka palekana o kona hoʻohana.
I kēia hihia, aia nā kūlana e pāpā ʻia ai ka hoʻohana ʻana i ka lāʻau.
Hoʻololi ʻia kahi hoʻomākaukau papa papa e lawe ʻia i loko o kēia mau hihia:
- me ka hoʻomohala ʻana i ka maʻi diabetes-dependence form;
- i ke wā kamaliʻi, no ka mea, ʻaʻole i lawe ʻia nā aʻo ʻana e pili ana i ka hopena o ka lāʻau lapaʻau ma ke kino o ke keiki, ʻike mau ʻia kona hopena i kēia lā;
- ʻaʻole hiki ke hoʻohana ʻia ka lāʻau lapaʻau inā he maʻi nui hou ka mea maʻi i kekahi o nā mea nui aʻe o ka ʻano;
- inā he hoʻomohala ʻana o ka ketoacidosis maʻi maʻi;
- i ka wā hāpai a ma ka umauma.
Eia kekahi, me ka makaʻala nui, pono ia e hoʻokō i kahi papa hana lapaʻau no ka poʻe maʻi e loaʻa nā pilikia koʻikoʻi me ka hana o nā keiki. ʻO ia ke kumu, pono ʻoe e hoʻoholo kūʻokoʻa i ka hoʻohana ʻana i ka lāʻau lapaʻau.
Pono e hoʻokele ʻia ka Therapy e like me ka alakaʻi a ma lalo o ka nānā ʻana o kahi olakino maʻi.
Nā hopena ʻaoʻao a me nā hopena maikaʻi aʻe
He nui nā hopena maikaʻi aʻe o ka lāʻau ʻoviavia, ʻaʻole e like me nā lāʻau lapaʻau e hoʻohaʻahaʻa ana i ke kō.
Hoʻohana maʻalahi ka hāmeʻa ikaika i ke kino, hoʻomaʻamaʻa ʻole me ke kumu ʻole hoʻopiʻi.
Eia kekahi, i kekahi mau mea, hiki mai nā hopena maikaʻi ʻole mai nā ʻokoʻa āpau a me nā ʻōnaehana o ke kino.
Ma ke kānāwai, ua lilo nā hopena maikaʻi ʻole ma hope o ka hōʻemi ʻana i ka lāʻau.
Hiki ke loaʻa ka maʻi ʻino ma ka ʻaoʻao o ka ʻōnaehana o ka maʻi ma ke ʻano o ka nasopharyngitis a i ʻole nā maʻi maʻi o ka ʻeha o ka ʻōpū.
Eia kekahi, hiki ke hoʻopiʻi ka mea maʻi no ka hoʻomohala ʻana i nā ʻano hana:
- Nā poʻokela ʻeha.
- ʻO ka ʻeha ma loko o ka ʻōpū, hui pū ʻia e nā puʻu mai o ka ʻōpū, ka luaʻi, a i ʻole ka ʻūhā.
- ʻO ka hōʻike ʻana o ka hypoglycemia.
- E like me nā hualoaʻa o nā loiloi, hiki i nā kūlike i kēia manawa - ke piʻi nei ke kiʻekiʻe o ka waikika uric a me nā neutrophils, e emi ana ke kahe o ka alkatine phosphatase.
Eia kekahi, hiki ke loaʻa i ka piʻi me ka hiamoe mau i ka nui o nā hōʻike maikaʻi ʻole, ma muli o ke ʻano e kuhikuhi ʻole ʻia e hoʻokele i nā kaʻa a hoʻokō paha i nā hana me nā hana e koi ai i ka piʻi nui o ka makaʻala.
ʻO nā loiloi o nā mea kūʻai a me nā limahana olakino
I waena o nā mea maʻi he nui i hoʻohana i ka lāʻau lapaʻau, ʻo nā loiloi e pili ana i ia mea i ka hapanui o nā kūlana he kūpono.
ʻO nā loiloi maikaʻiʻole e pili pinepine ana i ka mau hōʻino ʻana i nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana o ka lāʻau lapaʻau.
E pili ana iā Januvia, ua hōʻike nā loiloi he nui nā pono o ka lāʻau lapaʻau.
ʻO nā pōmaikaʻi nui loa o kahi limahana hypoglycemic, i hoʻohālikelike ʻia me nā lāʻau lapaʻau e hoʻemi ana i ke kō.
- aia ka hana o ke kaila kakahiaka i loko o ke koko, uku ʻia ka uku i ka hue i kapa ʻole ʻia;
- ma hope o ka ʻai ʻana, e hana wikiwiki ka lāʻau lapaʻau, hana maʻamau i ka pae o ka glycemia;
- pau ka pau ʻana o ke koko ʻaʻole i "spasmodic" i loko o ke kūlohelohe, hāʻule a hāʻule paha i kū ʻole ʻia.
Pono e haʻi ʻia e like me nā ʻōlelo aʻo no ka hoʻohana ʻana i ka lāʻau lapaʻau, hiki ke kiʻi ʻia nā papa i kēlā me kēia manawa o ka lā, me ka ʻano o ka kōʻai ʻana o ka meaʻai.
Ma ka manawa like nei, makemake ka poʻe maʻi i ka lāʻau lapaʻau kakahiaka, me ka hoʻopiʻi ʻana ma kēia ala e ʻike ʻia kahi hopena maikaʻi loa a haʻi ʻia, no ka mea e uku ka lāʻau lapaʻau i ka meaʻai e hiki mai ana i ke ao.
ʻO ka manaʻo o nā kauka ke ʻano ʻaʻohe ʻokoʻa i ka wā e lawe ai i ka lāʻau lapaʻau a ʻo ke kānāwai nui ka hahai ʻana i ka hoʻoponopono ʻana a mai hopohopo i ka noi hou. He hana ia e ʻae ai i ka therapy i ka hopena maikaʻi.
I kekahi mau pilikia, hōʻike ka maʻi maʻi ma hope o kekahi manawa, ua hoʻomaka ka hopena therapeutic o ka lāʻau i ka emi a e lele i nā pae glucose i hoʻomau ʻia. Hōʻike ʻia kēia kūlana ma ka ulu hou ʻana o ke kaʻina pili.
Wahi a nā mea maʻi, ʻo ke kākuhi nui o Januvia ke kumu kūʻai kumu o ka lāʻau lapaʻau.
ʻO ke kumukūʻai o kahi lāʻau lapaʻau me ka nui loa ma ke ʻano he ʻokoʻa ma ka 1,500 a i 1,700 rubles i kēlā me kēia pā (28 mau papa).
No nā maʻi maʻi he nui, e lilo ke kumukūʻai o ke kumukūʻai, ke hāʻawi pono nei e lawe pono ʻia ka lāʻau lapaʻau, a ʻo ka pā o ia puʻu e mau ʻia ma mua o hoʻokahi mahina.
ʻO ia ke kumu, hoʻomaka ka poʻe maʻi e huli i nā lāʻau lapaʻau e pili ana i ka ʻoi aku ka hapa nui.
Nā kikowaena Hypoglycemic
Hiki ke kūʻai ʻia ʻo ʻOviavia a me nā analogue i nā hale kūʻai inā loaʻa kahi lāʻau lapaʻau i kauoha ʻia ai e kāu kauka.
I kēia mau lā, ʻaʻole hiki i nā lāʻau lapaʻau Lūkini ke hāʻawi aku i nā analog kiko me ka mea like pū me nā mea kūʻai aku.
Inā mākou e hoʻohālikelike i ka code ATX-4 ma ka kue maoli, a laila hana kekahi mau analogues o Januvia i mea pono i mea e hoʻohana ai i nā lāʻau i mea waiwai.
ʻO ka Onglisa kahi mākēkē hypoglycemic hoʻohana i hoʻohana i nā hana maʻamau i ke kiʻekiʻe o ka glucose koko. ʻO ka papa hana koʻikoʻi kahi saxaglipin ma nā papa he ʻelua a ʻelima a ʻelima paha milligrams. Hoʻokomo ʻia ka lāʻau lapaʻau i ka pūʻulu o DPP-4 inhibitors. Hoʻohana pinepine e like me ka hui pū ʻana i hui pū ai me nā papa i kau ʻia i ka metformin. ʻO ke kumukūʻai o ka lāʻau lapaʻau e pili ana i ka 1800 rubles.
ʻO Galvus Met - kahi ʻelua o nā māhele nui - vildagliptin a me metformin hydrochloride. ʻO ka mea mua he ʻelele o ka papa o nā mea hoʻokalakupua o ka insular apparatus o ka pancreas a kōkua i ka hoʻonui ʻana i ka naʻau o nā selela beta i ke kō i komo mai i ka hapanui e like me ka wā i pōʻino ʻia.
Ma kēia hihia, ʻoki ʻia ka metformin hydrochloride i ke kaʻina hana o ka glucoseoneogenesis, e hoʻoulu i ka glycolysis, e alakaʻi ana i ka holomua o ka glucose ma o nā ʻola a me nā kiko o ke kino. Eia kekahi, aia kahi wīwī i ka lawe ʻana o ka glucose i nā sela ʻeha. ʻAʻole alakaʻi ke lāʻau lapaʻau i ka hoʻomohala ʻana o ka hypoglycemia. ʻO ke kumu o kahi hāmeʻa mai 1300 a 1500 mau rubles.
ʻO Galvus i kona hopena e like me Galves Met, koe wale nō kahi mea e kaha ai - vildagliptin. ʻO ke kumukūʻai o ka lāʻau lapaʻau mai 800 mau rubles.
Kūʻai - kahi papa lāʻau me ka hopena hypoglycemic i haʻi ʻia. ʻO ke kumu hana nui a linagliptin. ʻO nā hiʻohiʻona nui o ka lāʻau lapaʻau e pili ana i ka hiki ke hoʻomohala i ke kiʻekiʻe o ka glycemia, kahi nui o ka neʻe ʻana o ka incretins, kahi piʻi i ka huna ʻia ʻana o ka glucose o ka insulin. ʻO ke kumukūʻai o Transgent ma kahi o 1700 rubles.
ʻO kekahi o nā lāʻau lapaʻau e kōkua i ka pale ʻana i ke kiʻekiʻe o ka glucose kiʻekiʻe a hoʻopaʻa i ka hoʻomohala ʻana o ke kaʻina pili, hiki i ke kauka hele ke hoʻoholo. ʻAʻole ia e hāʻawi i ke kūʻokoʻa ʻana i nā lāʻau i kuhikuhi ʻia e kekahi lāʻau lapaʻau.
ʻO nā mea lawelawe kūpono hypoglycemic i wehewehe ʻia i ke wikiō ma kēia ʻatikala.
