Combogliz Prolong 1000 mg: mau loiloi a me nā ʻōlelo e pili ana i ka hoʻohana ʻana i nā papa

ʻO ka maʻi ʻo Comboglyz Prolong he lāʻau hypoglycemic. Hoʻohana ʻia e nā mea maʻi me ka maʻa type type 2, inā he ʻai haʻahaʻa-lā a me ke ʻano hana e hiki ai ke mālama i ka pae o ka glucose.

ʻO kahi maʻi nui ʻo Diabetes mellitus kahi maʻi koʻikoʻi e pono ai ka mālama kūikawā. Inā waiho ʻia ka maʻi nui i ka manawa, e komo i ka "pai" o nā hoʻopiʻi, mai ka retinopathy a gangrene, ka hoʻonā wale ʻana i nā ʻāpana o nā limahana.

ʻO ka mālama ʻana i ka maʻi kō e pili ana i ka ʻehā mau ʻōhua nui: kahi kīʻai olakino, hoʻomaʻamaʻa, mālama mau i ke kōpaʻa o ke kō, mālama ʻana i ka lāʻau (a i ʻole ka maʻi ʻolua no ka maʻi type 1).

Eia nō kekahi, pono e hoʻohana ʻia ka hoʻohana ʻana i nā lāʻau lapaʻau me ka lāʻau koʻikoʻi a me ka makaʻala. No laila, pehea e lawe pololei ai iā Combogliz Prolong i ʻole e hōʻino iā ʻoe iho? He aha nā ʻōlelo a nā kauka a me nā mea maʻi e pili ana iā ia? E hoʻāʻo kākou e hoʻomaopopo i kēia mau hihia.

ʻO ka hana lāʻau lapaʻau ma ka lāʻau

Ke hana nei ka lāʻau lapaʻau e ka hui lāʻau lapaʻau ʻAmelika ʻo Bristol-Myers Squibb.

Hana ka mea hana i ka lāʻau lapaʻau i ke ʻano o nā papa i loaʻa i ʻelua mau mea ikaika - metformin a me saxagliptin i nā ʻano kūpono: 1000 mg a me 2.5 mg, 500 mg a me 5 mg, 1000 mg a me 5 mg.

Eia kekahi, ʻo ka papa pākuʻi e pili ana i kahi helu liʻiliʻi o ia mau mea kōkua:

• magnesium stearate;
• sodium carmellose;
• hoʻohuʻihuʻi.

Hoʻopili ʻia kēlā me kēia papa o kēia lāʻau i nā kolu i ʻekolu, kahi i hoʻohui ʻia nā ʻano mea ʻē aʻe. No ka hoʻohui ʻana o ka lāʻau lapaʻau i nā ʻaihue hypoglycemic ʻelua, e hoʻopau pono ana ia i ka pae o ke kō i loko o nā mea maʻi. E noʻonoʻo i nā hiʻohiʻona o ka hopena i ka neʻe o ka glucose i kēlā me kēia.

ʻO Metformin, he ʻelele no ka hui biguanide, hoʻonui i ka hoʻohaʻahaʻa glucose, a laila e hoʻohaʻahaʻa i kona pae i ke koko o nā maʻi maʻi maʻi. ʻAʻole kēia alakaʻi i ke kūkulu ʻana i kahi kūlana hypoglycemic a me ka hyperinsulinemia. Hana ʻia nā hana metformin:

1. E hoʻemi i ka hana o kaʻili ma ka ate.
2. He hoʻonui ma ke kaʻe o kēlā me kēia peipheral.
3. No ka hoʻohanaʻana i ka glucose.
4. No ka hoʻonui i ka hiki i ke kele ma ka insulin.
5. E hoʻēmi i ka uptake glucose ʻōpū.

Pono e haʻi ʻia ma ka hoʻohana ʻana o Metformin, ʻaʻohe hoʻololi i ka kaohi o ke kōkōlō gula hoʻohiolo. Eia naʻe, pono e makaʻala ke kiaʻi i ka kakahiaka a i ka wā ʻai, ke hāʻule paha nā pae insulin.

Ua hoʻonāukiuki ʻo Saxagliptin i ka hoʻokuʻu ʻana o nā hormones infletin, ʻo ia hoʻi, ʻo HIP a me GLP-1, e kū nei mai ka ʻōpū i loko o ke kahe koko. Hāʻawi lākou i nā kaʻina hana:

• ka hoʻokuʻu mai o ka insulin mai nā hana beta o ka ʻaukā o ka islet;
• ka hoʻemi ʻana i ka hana o glucagon e nā cell alpha pancreatic.

ʻO kahi hiʻohiʻona o ka saxagliptin, ʻo ia ka māhele o ka hōʻemi i ka hoʻoliʻiliʻi o ka mea maʻi ma luna o kahi ʻōpū ʻole a i ka wā o ka pāʻina.

Ma hope o ka lawe ʻana i ka mea i koi ʻia o Combogliz Prolong, ua nānā ʻia ka mea kiʻekiʻe o ka metformin ma hope o ʻehiku mau hola.

ʻO Saxagliptin, ma ke ʻano he lula, ka hoʻohālikelike ʻia, hana i ka metabolite nui, a me ka metformin i hoʻopiki ʻole ʻia. No laila, ke hoʻololi ʻia nei lākou ma o nā keiki.

Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau

Pono koke e hoʻomanaʻo i ka lāʻau kūʻai ke kūʻai wale ʻia ma ka lāʻau lapaʻau. Pono ka mea nāna e kuhikuhi i kēia lāʻau lapaʻau e koho iā ia ma muli o nā loina e like me ka pae o ka glucose, ka hiki ʻana o nā maʻi concomitant, a me ke ola kino o ka mea maʻi.

Ke loaʻa ka mea maʻi i kēia mea hana, pono e aʻo ʻia nā ʻōkuhi no ka hoʻohana ʻana. Inā loaʻa iā ʻoe kekahi mau nīnau, pono e nānā pono ka mea maʻi me kāu kauka.

ʻO ka lāʻau lapaʻau ʻo Combogliz Prolong e lawe ʻia i ke ahiahi i ke ahiahi. Pono ka mea maʻi e hoʻomoʻi i ka papa āpau a inu i ka wai.

I ka hoʻomaka o ka hoʻōla, ʻo ka nui o ka lāʻau lapaʻau ka 500 mg + 2.5 mg i kēlā me kēia lā, ʻoi aku ka manawa hiki ke hoʻonui ʻia a hiki i ka 1000 mg + 5 mg (2 papa). No ka mea hiki i ka metformin ke hopena maikaʻi i ka hoʻopili ʻana, pono e hoʻonui ʻia kona nui o ka make. ʻAʻole pono ke makaʻu i kēlā mau loli i ke kino: ma muli o ke ʻano o ka hoʻohālikelike ʻana i ke ʻano, ua kūkulu hou ʻia ka hana a ka gastrointestinal tract. Ma muli o ka hoʻopiʻi ʻana o ka mea maʻi i ka nausea, ka luaʻi nui, ka maʻi palaka, ka mea ʻono ʻāhaʻi i loko o ka waha, ka nele o ka ʻono a me ka lemulewa.

Ke hoʻololi nei i ka lapaʻau me Combogliz Prolong me nā lāʻau lapaʻau haʻahaʻa, pono ʻoe e akahele nui. Kēia hoʻoholo e like me ka ʻae ʻana me ke kauka hele mai. ʻO kēia ma muli o ka hana ʻole o ka mea hana i nā noiʻi kūikawā e pili ana i ka hopena a me ka hōʻino ʻole ʻana i ka lāʻau lapaʻau ʻo Combogliz Prolong ma hope o ka hoʻohana ʻana i nā mea hoʻohana hypoglycemic ʻē aʻe.

Eia naʻe, me ka hoʻohana like ʻana o ka lāʻau a me nā mea paʻa o CyP3A4 / 5 isoenzymes, pono pono e lawe i ka haʻahaʻa loa ma kaxagliptin - 2,5 mg. Kūkākūkā ia mau mea:

1. Indinavir.
2. Ketoconazole
3. Aezodon.
4. Itraconazole.
5. Atazanavir me nā mea ʻē aʻe.

Pono nā maʻi maʻi ʻōpio e hoʻohana i ka lāʻau lapaʻau me ka mālama aka, me ka noiʻi ʻana i hōʻike ʻia hiki iā ia ke alakaʻi i ka hana ʻana i ka lua.

Pono ke mālama i ka lāʻau lapaʻau i kahi mahana ʻaʻole iʻoi aku + + degrees Celsius. Pono ka poʻeʻelemakule e hōʻoia i ka hele ʻole o nā keiki liʻiliʻi i ka pale i pale i nā hopena maikaʻi ʻole.

ʻO ka 3 papa makahiki i kona manawa, i ka wā e pau ai, ʻaʻole i pāpā ʻia ka hoʻohana ʻana i ka lāʻau.

Nā maʻi hoʻohālikelike i ka hoʻohana ʻia ʻana o ka lāʻau lapaʻau

No ka mea, ʻaʻohe ʻepekema ʻepekema ma ka hana o ka hopena a me ka hōʻino ʻole o ka lāʻau lapaʻau Comboglize, ʻokoʻa ka ʻōlelo i kona hoʻohana ʻana i ka wā kamaliʻi (ʻoi aku ma mua o 18 mau makahiki), ʻo ia hoʻi i ka wā o ka gestation a me nā umauma. Eia nō hoʻi, ʻo ka hopena o ka lāʻau lapaʻau ma ke kino o nā poʻe maʻi me ka maʻi type kīpē 1 a me ka nānā ʻana i nā maʻi insulin i ʻike ʻole ʻia.

Eia kekahi i nā contraindications aʻe i luna, ua pāpā ʻia ka maʻi diabetes i ka lawe ʻana i ka lāʻau i loko o ia mau hihia:

• me ka hoʻomanawanui ʻole ʻana i nā ʻāpana o ka lāʻau;
• me ka galoleose intolerance mai ka hānau ʻana, me ka malabsorption glucose-galactose a me ka nele o ka lactase;
• i nā hopena koʻikoʻi o ka hiki ʻana i ka hōʻeha i ka DPP-4 inhibitor (no ka laʻana, angioedema, anaphylaxis);
• ma ke alo o nā maʻi mānoanoa e hiki ai ke alakaʻi i ka hana ʻole i kahi maʻi: i ke ala, ka maʻi hypoxia (sepsis, pīhoihoi, nā maʻi bronchopulmonary, nā maʻi o ka huehue), nā ʻano maʻi like ʻole, ka huehue ma muli o nā maʻi ʻeha a hoʻomau;
• me ka renal dysfunction, i ka mea me ka serum creatinine e emi mai ma kahi o 1,4 mg / d (no nā wahine) a emi mai ka 1,5 mg / dl (no nā kāne), a me ka hoʻomaʻemaʻe i kahi mea hana aine i hana ʻia ma muli o ka septicemia, nā alaʻeha nui o ka ʻōnaehana cardiovascular;
• me ka metabolic acidosis, ma ka maʻi ketoacidosis maʻi maʻi;
• me ka maʻi maʻi precoma a me ka coma;
• i ka heleʻana o nā maʻi a me nā maʻi e hoʻonui ai i ka hiki o ka hypoxia kiko;
• me ka hoʻolaha ʻana o ka iodine-ka mea hoʻokaʻawale i ʻelua mau lā ma mua a ma hope o nā hoʻokolokolo x-ray a me nā radioisotope;
• ke noho ana i kahi meaʻai kūikawā (liʻiliʻi i lalo o 1000 kcal i ka lā);
• me ka waiʻona koʻikoʻi me ka ethanol a i ʻole ke kalaʻana i ka palaka;
• me nā hana pale a me nā hōʻeha koʻikoʻi e koi ana i ka hoʻomaka ʻana o ka insulin;
• me ka ukana oʻe;
• me ka acidosis lactic.

E like me ka mea i ʻōlelo ʻia ma mua, i ka hoʻohana pono ʻana o ka lāʻau lapaʻau Combogliz Prolong e pono me ka mālama kūikawā i nā poʻe maʻi maʻi (mai 60 mau makahiki he nui), ʻo ia hoʻi ka poʻe e pili pū ana me ka hana kaumaha kino nui, a me nā mea i loaʻa i ka pancreatitis.

Hoʻolilo kūlohelohe a me ka overdose

I kekahi mau hihia, ma muli o ka hoʻohana pono ʻana i ka lāʻau, hiki ke nānā ʻia ke ʻano o ka hopena maikaʻi ʻole. Ke hōʻike nei kēia papa ʻāina i nā hopena ʻokoʻa maʻamau e pili ana i ka hoʻohana ʻana iā Combogliz Prolong.

Eia nā mea, i ka wā noiʻi noiʻi, ua ʻike ʻia no ka manawa lōʻihi e lawe i ka saxagliptin, aia kahi nui o ka nui o nā lymphocytes, a me ka huaora B12.

ʻO nā hihia nui loa he mea liʻiliʻi loa ia, eia naʻe, me ka hoʻohana lōʻihi ʻana i ka lāʻau lapaʻau, hiki nō. ʻAʻole alakaʻi ʻo Saxagliptin i ka hoʻohuihui o ke kino, akā inā kahi overdose hiki ke hoʻopau ʻia me ka hoʻohana ʻana i nā kaʻina hemodialysis. Hoʻonohonoho ʻia nei ke ʻano maʻi Symptomatic.

Nui nā hihia i hoʻopaʻa ʻia o ka overdose o ka metformin. ʻO nā hōʻailona nui ka hypoglycemia a me ka lactic acidosis, ka mea i hele pinepine ʻia e ka renal gagal. ʻO nā hōʻailona nui ka ka maʻi lactic acidosis nā:

1. Pāʻeha
2. Hōʻalo kahi.
3. ʻEha ka ʻōpū.
4. ʻO ka hypypension a i ʻole ka hypothermia.
5. Myalgia.
6. Kūleʻa Bradyarrhythmia.

I ka hihia maikaʻi loa, hiki mai ka hilahila, hiki ke alakaʻi i ka hoʻomohala ʻana i ka coma. ʻO nā mea nui o ka hypoglycemia ka momona, hānai, nāwaliwali, nā hiamoe, ka huhū, nāwaliwali. Hoʻopili ʻia ka Metformin 850 e ka hemodialysis, pono e noʻonoʻo i ka hoʻopili ʻana a hiki i ka 170 ml i hoʻokahi mau minuke.

I mea e pale aku ai i ka make nui a me ka hopena, pono ka mea maʻi e hahai i nā ʻōlelo a ke kauka a pau i hele ʻole i ka lāʻau lapaʻau ponoʻī.

ʻO kēia nā kumuhana nui ʻelua e pale aku i nā hopena maikaʻi ʻole.

Hoʻopili pū me nā lāʻau ʻē aʻe

Pono e hoʻomanaʻo ʻia ʻaʻole hiki i nā lāʻau lapaʻau ke hoʻohana pū me nā mea ʻē aʻe. No ka mea aia ke ʻano like ʻole o nā kūmole ma waena o nā mea a nā lāʻau lapaʻau, hiki i kēia ke hana i nā hopena kūlike.

No laila, hiki i kekahi mau lāʻau ke hōʻemi i ka hopena hypoglycemic o ka saxagliptin a me ka metformin, ma muli o ke ʻano, e piʻi ka pae o ka glucose i ke koko. Ke hoʻopiʻi nei, e hoʻoikaika nā poʻe ʻē aʻe i ka hopena o ke kōpae o nā hiona, e waiho ana i ka emi wikiwiki o kaʻili gula.

No laila, pāpā ʻia ʻoe ke inu i kāu lāʻau lapaʻau ponoʻī. ʻO ka mea mua pono ʻoe e ʻike i ke kauka i hiki ke koho i ka ʻano kūpono o nā lāʻau lapaʻau.

ʻO ke kumukūʻai a me nā loiloi o nā kauka, nā maʻi

Ma hea e kūʻai ai iā Combogliz Prolong? Maikaʻi, hiki ke kūʻai ʻia aku ka lāʻau lapaʻau ma kahi lāʻau kūʻai maʻamau a waiho i kahi kauoha ma ka pūnaewele mana o kahi mea kūʻai aku Lūkini.

ʻO ka lāʻau i koho ʻia e ka mea maʻi e pono e hoʻohālikelike i ʻelua mau hiʻohiʻona - ka hopena therapeutic a me kona kumukūʻai.

Aia ke kumukūʻai o ka lāʻau lapaʻau ma muli o kona ʻano o ka hoʻokuʻu ʻana, no laila, ʻokoʻa ka loli ma loko o ia mau palena:

• 1000 mg + 5 mg (28 mau pālolo no kēlā me kēia paʻi): mai 2730 a 3250 Lūkini Lūkini;
• 1000 mg + 2.5 mg (56 papa i kēlā me kēia pū): mai 2,600 a 3,130 mau rubles Lūkini.

E like me kāu e ʻike ai, ʻike nui ke kumukūʻai, no ka mea, ʻo Combogliz Prolong kahi lāʻau lapaʻau i hoʻokomoʻia. ʻO kēia kahi mea nui, ʻoiai ka mea hiki i nā mea maʻi me nā hōʻemi haʻahaʻa a me nā mea hōʻemi ke hiki ke loaʻa i kēlā lāʻau lapaʻau.

Pono e manaʻo ʻia ʻaʻole nui nā ʻōlelo e pili ana i ka hoʻohana ʻana i ka lāʻau lapaʻau e nā mea maʻi. Basically, ma ka Pūnaewele hiki iā ʻoe ke ʻike i nā loiloi o nā kauka, he nui i kapa ʻia he mea pono kēia ʻano hana. Wahi a lākou, ʻaʻole pono ka lāʻau lapaʻau i ka pae o ka glucose i ka maʻi maʻi maʻi maʻi, akā e kōkua pū ana i ka mālama ʻana i ko lākou momona, mahalo i ka metformin i loko.

Eia nō naʻe, ʻo ka mea e hoʻopiʻi ana i nā kumu o ka mālama ʻai i ka maʻi mellitus no ka maʻi mellitus a ua hana pinepine ʻia i ka hoʻoikaika kino e hiki ke hōʻemi i ke kaumaha kino. E like me kā lākou e ʻōlelo nei, ʻaʻohe pilau kilokilo mai nā maʻi āpau.

No laila, ʻo ka hapanui o nā mea maʻi e hoʻomaopopo he pono loa ka hopena therapeutic o ka lāʻau: ma hope o kona hoʻohana ʻana, e mālama ʻia ka nānā ʻana o ke kōpaʻa koko. Akā hiki i kona pae ke "lele" i ka wā ʻaʻole e hahai ka mea maʻi ma ka papa ʻaina, e ʻae ʻo ia iā ia i ka ʻoli a me nā meaʻai i ʻāpono ʻia.

Ma keʻano holoʻokoʻa, hiki ke hoʻomaopopo i ka ʻo Combogliz Prolong he lāʻau lapaʻau pono a maikaʻi loa. Eia nō naʻe, pono ʻoe e nīnau i ke kauka e pili ana i kona hoʻohana.

Nā lāʻau like ʻole

I kekahi manawa ke lawe nei i ka mea maʻi i nā mea maikaʻi ʻole. ʻO kēia paha ma muli o ka hakakāʻana i kāna mau ʻāpana, nā ʻano contraindications a me nā mea like.

I kēlā mau hihia, hoʻomaka ke kauka e hoʻoponopono i ke hoʻoponopono lāʻau a koho i kekahi lāʻau lapaʻau e like me nā hopena therapeutic. Ma waena o nā mea kaulana kaulana o ka lāʻau Combogliz Prolong, e koho:

1. Yanumet - kahi lāʻau lapaʻau e pili ana i ka metfomin a me ka saxagliptin. ʻO ka ʻokoʻa nui ka hiki i ka Janumet ke lawe pū me ka maʻi insulin, me ka gamma receptor agonists. ʻO nā loiloi o nā maʻi maʻi e loaʻa mai nei i kahi ʻano like ʻole o ka maʻi like ʻole o ka maʻi i mea maikaʻi loa. ʻO ke kumukūʻai kūpono o ka lāʻau Yanumet (100 mg + 50 mg, 56 papa) ʻo 2830 mau rubles.
2. ʻO Galvus Met kahi lāʻau lapaʻau ka mea nui o ka vildagliptin a me ka metfomin. ʻOiai he ʻokoʻa ia ka hoʻohālikelike ʻana me Combogliz Prolong, he like ia me ka hopena hypoglycemic like. Hiki ke hoʻohui pū me ia i ka insulin, sulfonylurea derivatives, a me ka metformin. ʻO ka awelika kumukūʻai o ka 1 māpuna i loaʻa nā papa 30 (50 mg + 1000 mg) ka 1,540 mau rubles.
3. ʻO Xr comboglyce kekahi hypoglycemic maikaʻi. Loaʻa ia me metformin a me saxagliptin. Hoʻoholo ʻia ka hopena o ka lāʻau ʻo Comboglize Xr e ka mea e hele nei i ka loea, e mālama ana i ke kūlana o ka mea maʻi. ʻO ka lāʻau lapaʻau ʻo Combogliz Xr, e like me Combogliz Prolong, ʻaʻole i hoʻohana ʻia i nā keiki a me nā wahine hāpai. Ma waena o nā hopena maikaʻiʻole me ka Combogliz Xr, hiki ke hoʻomaopopo ʻia he like lākou me ka Combogliz Prolong. ʻO ke kumukūʻai kūpono o Xr Comboglise (2.5 + 1000mg, 28 mau papa) he 1650 rubles.

No laila, ʻo Combogliz Prolong kahi lāʻau lapaʻau maikaʻi i ka hakakā me nā hōʻailona o ka maʻi maʻi, i ka ʻano me ka hyperglycemia. Akā, inā hiki ʻole ke kūʻai aku, e koho i ke koho kūpono loa e loaʻa ka hopena maikaʻi.

Hoʻopiliʻia ma Combogliz Prolong, aia kekahi mau lāʻau lapaʻau haʻahaʻa. E haʻi aku ka mea loea iā ʻoe hou e pili ana iā lākou i ke wikiō ma kēia ʻatikala.