ʻO KA PROTAFAN INSULIN: KA WEHEWEHE ʻANA, NĀ LOILOI, NĀ KUMU KŪʻAI

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ʻO ka insulin Protafan e pili ana i ka insulin manuahi-hana.

ʻO ka pono e hoʻohana i ka lāʻau Insulin Protafan NM penfill hiki ke hele pū me kekahi mau maʻi a me nā kūlana. ʻO ka mea mua, me ke ʻano type o ka maʻi type a me ka 2. Eia kekahi, hōʻike ʻia ka lāʻau lapaʻau i ke kahua o ke kū'ē i nā lāʻau lapaʻau hypoglycemic mua.

Hoʻohana pū ʻia ka lāʻau lapaʻau me ka hui pū ʻana me ka mahele (ʻāpana kūwaho i ka lāʻau hypoglycemic oral) inā loaʻa ka maʻi maʻi i ka wahine hāpai a inā ʻaʻole kōkua ka lāʻau lapaʻau;

ʻO nā maʻi hōʻeha a me nā hōʻemi manuahi (hoʻohui ʻia a i ʻole monotherapy) hiki nō hoʻi ke kumu no ka hoʻonoho ʻana.

Pehea e hiki ai iaʻu ke hoʻololi i ka lāʻau lapaʻau, nā kikowaena

Insulin Bazal (kumukūʻai e pili ana i 1435 rubles);
Humulin NPH (kumukūʻai e pili ana i 245 mau rubles);
Protafan NM (kumukūʻai e pili ana i 408 mau rubles);
Aktrafan NM (kumu pili
Protafan NM Penfill (kumukūʻai e pili ana i 865 rubles).

Nā hiʻohiʻona o ka lāʻau lapaʻau

ʻO ka lāʻau lapaʻau kahi hoʻopiʻi i hoʻokomo ʻia ma lalo o ka ʻili.

A hui, ʻano waiwai:

Isulin insulin-human semisynthetis (human semisynthetic). Loaʻa iā ia kahi manawa maʻamau o ka hana. ʻO ka Protafan NM ka contraindicated ma: insulinoma, hypoglycemia a me hypersensitivity i ka mea ikaika.

Pehea e lawe ai a ma loko o ka aha ka palena?

Hoʻokomo ʻia ka Insulin i hoʻokahi manawa a ʻelua paha i ka lā, hapalua hola ma mua o ka ʻaina kakahiaka. Ma kēia wahi, kahi e hana ʻia ai nā inikini, e pono e loli mau.

Pono ke koho o ka paukū no kēlā me kēia maʻi pākahi. Aia ka nui o kona puʻupuʻu i ka nui o ka glucose i loko o ka pāʻai a me ka hoʻokahe koko, a me nā hiʻohiʻona o ke ala o ka maʻi. Pōʻai ʻia, ke kau ʻia nei ka pona ma ka manawa o ka lā a he 8-24 IU.

I nā keiki a me nā mākua e loaʻa ka hypersensitivity i ka insulin, ua hoʻemi ʻia ka nui o ka nui i 8 IU i kēlā me kēia lā. A no nā mea maʻi me ka haʻahaʻa haʻahaʻa haʻahaʻa, hiki i ke kauka hele ke kau nei i kahi maʻa iʻoi aku ma mua o 24 IU i kēlā me kēia lā. Inā he hapa ka lā o kēlā me kēia lā ma ka 0.6 IU i ka kileki, a laila e lawelawe ʻia ka lāʻau lapaʻau e ʻelua mau inikini, e hana ʻia ma nā wahi like ʻole.

ʻO ka poʻe maʻi e loaʻa ana i ka 100 IU a i hoʻokahi lā paha i ka wā e hoʻololi nei i ka insulin, pono mau i lalo o ka mākaʻi a nā kauka. Ke hoʻololi nei i ka lāʻau lapaʻau me kekahi e pono e hana me ka mālama mau loa ʻana i nā pae glucose i ke koko.

ʻO nā waiwai Pharmacological

Nā Inulin Protafan:

hoʻemi kahe koko glucose;
hoʻomaikaʻi i ke komo ʻana o ka glucose i loko o nā lau;
Hoʻonui ka hoʻonui i ka synthesis synt protein;
hoʻohaʻahaʻa i ka helu o ka hana glucose i ka ʻōpala;
hoʻonui i ka glycogenogenesis;
hoʻomaikaʻi i ka lipogenesis.

Hoʻokomo ʻia ka Microinteraction me nā ʻekaʻawa ma ke kūwaho o waho i ke ʻano o ka mea i ʻike i kahi mea ʻona. Ma o ka hoʻoulu ʻana i nā kōpona ate a me nā pūleʻa momona, ke kāpae ʻana o CAMP a i ʻole ke komo ʻana i loko o kahi ʻeha a pūpū, i hoʻāla ʻia ka insulin receptor paʻakikī i nā hana e kū ana i loko o nā kō.

Hoʻomaka ia i ke kāpili ʻana o kekahi mau enzyme koʻikoʻi (glycogen synthetase, hexokinase, pyruvate kinase, etc.).

He kumu ka emi ʻana o ke koena koko ma ke:

hoʻonui ka lawe i ka glucose i loko o nā pūpū;
hoʻonāukiukiʻana i ka glycogenogenesis a me lipogenesis;
hoʻonui i ke kinina a me ka hoʻopili ʻana o ka glucose e nā kiko;
protein synthesis;
i ka emi ʻana o ka loaʻa o ke kō e like me ka ʻōpala, i.e. kahi emi o ka ʻohi ʻana o ka glycogen a pēlā aku.

Aia a hea ka lāʻau i ka pehea a pehea e mau ai?

Ma hope koke iho o ka hoʻomaka ʻana o ke hoʻopanee ʻana, ʻaʻole i hopena. Hoʻomaka ʻo ia e hana i 60 - 90 mau minuke.

Loaʻa ka hopena kiʻekiʻe ma waena o 4 a me nā hola 12. ʻO ka lōʻihi o ka hana mai 11 a 24 mau hola - e hilinaʻi nui ia i ka ʻano a me ka hāmeʻa o ka insulin.

Nā hopena hopena

ʻO ka hypoglycemia (ka nānā a me ka ʻōlelo, pallor o ka ʻili, ke kūlohelohe, ka nui ʻana o nā luhiluhi, nā ʻano ʻē aʻe, ka palpitations, ka huhū, ka hopohopo, ke kaumaha, ka nui o ka makemake, ka hopohopo, ka hopohopo, ka hopohopo, ke kaumaha, ka hiamoe, paresthesia i loko o ka waha, ʻeha. ;

Allergic reaksi (hoʻemi i ke koko, urticaria, pōkole o ka hanu, ke kuni, ka angioedema);

I ka hoʻonui ʻia o ka ʻauhau o nā anti-insulin anti me ka hoʻonui hou aʻe i ka glycemia;

ʻO ka maʻi diabetes a me ka hyperglycemia (e pili ana i ke kua o ke aʻa a me ka maʻi, ka nele i kaʻai, kaʻai ʻana i nā hōʻaiʻai wai nui, nā helu ʻai liʻiliʻi): ka huehue i ke alo, ka hiamoe, ka nui o ka momona, ka makewai mau ʻole);

ʻO ka comyp Hlyoglycemic;

I ka hoʻomaka mua o ka hana maʻi - nā hewa refractive a me ka edema (kahi ʻano pōkole e ulu nei me ka mālama hou aku);

Hoʻowahāwahā i ka ʻike (i kekahi manawa he coma a me kahi kūlana precomatose e ulu);

Ma ka pūnaewele kahi o ka injection, itching, hyperemia, lipodystrophy (hypertrophy a atrophy of the subcutaneous fat);

I ka hoʻomaka ʻana o ka mālama maʻi, he pilikia kaohi helehelena;

ʻO nā hopena cross-immunological me ka insulin kanaka.

Nā hōʻailona o kahi overdose:

nahoa
haehae;
haʻi leo hypoglycemic;
palpitations
ʻōpala
paneʻike a me ka ʻōlelo;
hāpau
helehelena kikowaena;
hiamoe
hoʻonui nui momona;
ʻano ʻē;
Kuhi kaumaha
huhū
paresthesia i ka waha waha;
Hōʻikeʻike
palika
makaʻu
lie kanikela.

Pehea e mālama ai i kahi overdose?

Inā aia ka mea maʻi ma kahiʻike maopopo, a laila kuhikuhi ke kauka i ka dextrose, ka mea i lawelawe ʻia ma ka maʻi pā o ka maʻi, intramuscularly a i ʻole intravenously. ʻO Glucagon a i ʻole ka hopena hypertonic dextrose e mālama ʻia i ka hana intravenously.

Maloko o ka ahai hypoglycemic coma, 20 a 40 ml, i.e. ʻO 40% ka hopena dextrose a hiki mai ka mea maʻi mai kahi coma.

Nā manaʻo nui:

Ma mua o ka lawe ʻana i ka insulin mai ka pālāīa, pono ʻoe e nānā i ke kūlohelohe o ka hopena i loko o ka ipu i kahi ʻāpana waihoʻoluʻu. Inā uhi ka ua, ua pohō a ʻike ʻia nā kino ʻē aʻe.
ʻO ke ʻano o ka lāʻau lapaʻau ma mua o ka hoʻokele e pono ai ka mahana lumi lumi.
Ma mua o nā maʻi hopohopo, nā hana hoʻopiʻi o ka maʻi thyroid, ka maʻi Addiosn, ka loaʻa ʻole o ka pilikia renal, hypopituitarism, me nā maʻi maʻi maʻi o ka wā kahiko, pono ʻia ka nui o ka insulin e hoʻoponopono ʻia.

Hiki i nā kumu o hypoglycemia ke:

hemo
utuka
loli;
nā maʻi e hōʻemi ai i ka pono o ka insulin (ate a me nā maʻi o ka maʻi, ka hypofunction o ka nui o ka nui o ka thyroid gland, pituitary gland, adrenal cortex);
kūʻa ʻole me ka ʻaina o ka meaʻai;
ka pilina me nā lāʻau ʻē aʻe;
nā ninia
ke komo kino;
ka loli o ka pūnaewele injection.

Ke hoʻoneʻe nei i ka maʻi mai ka maʻi holoholona i ka insulin kanaka, hiki mai paha ke kaila ʻana o ka nui o ka glucose o ke koko. Pono ka luhi i ka insulin kanaka e hoʻāpono ʻia mai kahiʻike lapaʻau, a pono hoʻi e hana ma lalo o ka mākaʻikaʻi koʻikoʻi o kahi kauka.

I ka wā a ma hope o ka hānau keiki ʻana, hiki ke hoʻemi ʻia ka nui o ka insulin. I ka wā lactation, pono ʻoe e nānā i kou makuahine no kekahi mau mahina, a hiki i ka hoʻokū ʻana o ka pono o ka insulin.

ʻO ka predisposition i ka holomua o ka hypoglycemia hiki i kahi mea hōʻeha i ka hiki ke maʻi maʻi maʻi e holo i nā kaʻa a mālama i nā mīkini a me nā mīkini.

Ma ka hoʻohana ʻana i ke kō aʻai ʻole nā meaʻai i mea nui i nā kākeka, hiki i ka poʻe maʻi maʻi keʻake i ke kāohi i kahi ʻano hypoglycemia. Manaʻo ʻia e loaʻa i ka mea maʻi i ka liʻiliʻi o 20 g ka kōpili me ia.

Inā i hoʻopiʻi ʻia ka hypoglycemia, pono ia e hōʻike i ke kauka nāna e hoʻoponopono i ka maʻi lapaʻau.