Ma hope o ka nānā ʻana o nā analogues pōkole pōkole, ua hōʻea ke ʻano maʻi mellitus maʻi i ka pae hou loa: ka mālama paʻa ʻana o ka glycemia ma ka hapanui o nā maʻi i hiki i ka hopena, hiki i ka hōʻemi o ka maʻi microvascular, hypoglycemic coma.
ʻO Apidra ka ʻōpio muli loa o kēia hui, nā kuleana no ka lāʻau lapaʻau i ka hopohopo Farani e Sanofi, nona nā lālā he nui, aia kekahi ma Rūsia. Ua hōʻoia ʻo Apidra i nā pono ma mua o nā kānaka insulins pōkole: hoʻomaka a hoʻopau wikiwiki, hiki i kahi pae kiʻekiʻe. Ma muli o kēia, hiki i ka lolo maʻi ke hōʻole i nā meaʻai, ua liʻiliʻi loa i ka manawa o ka ʻai ʻana, a pale ʻia mai ka kali ʻana a hiki i ka hoʻomaka ʻana o ka hana. I ka huaʻōlelo, ua pale nā lāʻau hou i nā kuʻuna ma nā ʻano a pau. ʻO ia ke kumu e ulu mālie nei ka hapa o nā mea maʻi e hoʻohana ana i nā analog analog.
Nā ʻōkuhi no ka hoʻohana
| Hōʻike | ʻO ka mea hoʻonaninani he glulisin, ʻokoʻa ka mole o ke koʻi (endhesole (synthesized in the body)) i ka ʻaina amino e ʻelua. Ma muli o kēia kaulike, ʻaʻole i hoʻopili ka glulisin i ka hoʻopili ʻana i nā pūhui paʻakikī i loko o ke kihi a ma lalo o ka ʻili, no laila hoʻokomo koke i ke kahe koko ma hope o ke kūhai ʻia. ʻO nā mea kōkua i loaʻa i ka m-cresol, chloride a me ka sodium hydroxide, sulfuric acid, tromethamine. Hāʻawi ʻia ka kūpaʻa o ka hoʻonā ʻia e ka hoʻohui ʻana o ka polysorbate. ʻAʻole e like me nā hoʻomākaukau pōkole ʻē aʻe, ʻaʻole i komo ka insulin Apidra. ʻO ka hāleʻa kahi pale pH (7.3), no laila hiki ke hoʻoheʻe ʻia inā makemake ʻia nā koina liʻiliʻi. |
| Lapaʻau lāʻau | Wahi a ke kumu a me ka ikaika o ka hana, ʻo ka like me ka like me ka insulin e like me ke kanaka, ua ʻoi aku ia ma mua o ka wikiwiki a me ka manawa o ka hana. Hoʻopili ʻo Apidra i ka hoʻoneʻe ʻana o ke kō i loko o nā kīʻaha koko ma o ka hoʻoulu ʻana i kona kao ʻana ma o nā uaua a me ka iwi adipose, a ke pale aku nei hoʻi i ka synthesis o nā kūmole e ka ate. |
| Nā Hōʻike | Hoʻohana ʻia no ka maʻi diabetes i ka hoʻohaʻahaʻa haʻahaʻa ma hope o ka ʻai ʻana. Me ke kōkua o ka mea lapaʻau, hiki ke hoʻoponopono koke ʻia ka hyperglycemia, me ka hoʻopiʻi ʻana i nā maʻi o ka maʻi maʻi. Hiki iā ia ke hoʻohana i nā maʻi āpau mai ka 6 mau makahiki aku, ʻaʻohe o nā wahine a me ke kaupaona. E like me nā kuhikuhi, ua ʻae ʻia ka insulin Apidra no nā poʻe maʻi me ka maʻi hepatic a me ka renal a me ka lawa ʻole. |
| Nā Hoʻohui | ʻAʻole hiki ke hoʻohana no ka hypoglycemia.. ^ E Ha yM. Inā he haʻahaʻa ka hilo ma mua o ka ʻai, ʻoi aku ka palekana i ka lawelawe ʻana iā Apidra ma hope iki inā he maʻamau ka glycemia. ʻO nā hypersensitivity o gilluzin a i ʻole nā mea kōkua o ka hoʻonā. |
| Nā ʻōlelo kikoʻī |
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| ʻĀnō | Hoʻoholo ʻia ka nui o ka makemake e kau ʻia i ka nui o nā huamina i ka meaʻai a me nā mea hoʻololi pilikino o nā hua ʻai i nā ʻāpana o ka insulin. |
| ʻO ka hana makemake ʻole | ʻO nā hopena ʻino maikaʻiʻole iā Apidra i nā maʻi āpau o nā insulin. ʻAno ʻōlelo no ka hoʻohana ʻana i ka kikoʻī e pili ana i nā hana kūpono ʻole āpau. ʻO ka pinepine, ʻike ʻia ka hypoglycemia i pili i ka overdose o ka lāʻau. Hoʻohui ʻia lākou me ka nui o ka nāwaliwali, nāwaliwali, nā lūlū. Hoʻonui ka nui o ka puʻuwai naʻau i ka paʻakikī o ka hypoglycemia. Hiki i ke ʻano ke hypersensitivity i ke ʻano o ka edema, ʻalohi, ʻulaʻula hoʻi ma ka wahi i hoʻopaʻa ʻia. Ma o ka maʻamau o nalo aku lākou ma hope o nā pule he ʻelua o ka hoʻohana ʻana iā Apidra. Kuhi hewa ka hoʻonāukiuki ʻōnaehana, e koi ana i ka loli wikiwiki o ka insulin. ʻO ka hana ʻole e hoʻokō me ke kaʻina o ka hoʻokele a me nā hiʻohiʻona pilikino o ka kiko subcutaneous hiki ke alakaʻi i ka lipodystrophy. |
| ʻLelo ʻia a me GV | ʻAʻole keʻole o Insulin Apidra i kahi hapai olakino maikaʻi, ʻaʻole i hoʻopilikia i ka hoʻolālā intrauterine. Hāʻawi ʻia ka lāʻau lapaʻau e hoʻohana ʻia i nā wahine hāpai me nā maʻi ʻano 1 a me 2 a me ka maʻi maʻi gestational. ʻAʻole i lawelawe ʻia nā haʻawina e pili ana i ka hiki ʻo Apidra i loko o ka waiū umauma. Ma ke ʻano he lula, ua komo nā insulins i ka waiū i ka liʻiliʻi liʻiliʻi, ma hope o ka nahu ʻia o ka ʻanuʻu o ke keiki. Hoʻoholo ʻia ka nui o ka insulin i loko o ke koko o ke pēpē, no laila e emi ka holi ʻana. Eia naʻe, aia kekahi liʻiliʻi liʻiliʻi o ka hopena alerine i loko o kahi keiki i ka glulisin a me nā mea āpau o ka hoʻonā. |
| Hoʻohui nūhou | Hōwaliwali ka hopena Insulin: Danazol, Isoniazid, Clozapine, Olanzapine, Salbutamol, Somatropin, Terbutaline, Epinephrine. Hoʻohui like: Disopyramide, Pentoxifylline, Fluoxetine. ʻO Clonidine a me nā reserpine - hiki i nā mākeke hōʻailona ke hoʻomaka o ka hypoglycemia. Hoʻopilikia ka ʻawaʻawa i ka uku o ka diabetes mellitus a hiki ke hoʻonāukiuki i ka hypoglycemia koʻikoʻi, no laila e hōʻemi ʻia kona hoʻohana ʻana. |
| E hoʻokuʻu i nā palapala | Hāʻawi aku nā lāʻau lapaʻau iā Apidra ma SoloStar syringe penens. Hoʻokomo i kahi pahu pahu me kahi hoʻonā 3 ml a me kahi mea paʻa o ka U100 i waiho ʻia i loko o lākou kahi i hāʻawi ʻia ʻia kahi hana baloka. Kūleʻa penehiwehi penehi penehi - 1 ʻāpana. Ma ka pākuhi o 5 pene, wale nō 15 ml a 1500 mau ʻāpana o ka insulin. Loaʻa hoʻi ʻo Apidra i nā pahu wai 10 ml. Hoʻohana pinepine ʻia lākou ma nā wahi olakino, akā hiki ke hoʻohana ʻia e hoʻopiha i ke kaila i kahi pamu insulin. |
| Kūʻai | ʻO ka pōkole me nā uaki ʻona ʻo Apidra SoloStar e pili ana i 2100 rubles, kahi hoʻohālikelike e pili pono ana i nā analogues - NovoRapid a me Humalog. |
| Laki | ʻO 2 mau makahiki i ka noho pāla o Apidra, i hoʻolako ʻia i kēia manawa a pau i loko o ka friji. No ka hōʻemi i ka hopena o ka lipodystrophy a me ke kaumaha o nā injections, e hoʻomehana ʻia ka insulin i ka lumi o ka lumi ma mua o ka hoʻohana ʻana. ʻAʻohe kuhi i ka lā, i nā mahana a hiki i 25 ° C, ke hoʻomoʻa nei ka lāʻau lapaʻau i ka penu syringe i kona mau waiwai no 4 mau wiki. |
E noho mākou i nā kikoʻī hou aku i nā hiʻohiʻona o ka hoʻohana ʻana o Apidra, ʻaʻole i hoʻokomo i nā ʻōlelo aʻoaʻo no ka hoʻohana.
E kiʻi i ka uku ʻana i ka maʻi diabetes ma ʻApidra, pono ʻoe i:
- Hōʻalo i ka insulin 15 mau minuke ma mua o ka papaʻaina. Wahi a nā ʻōlelo kuhikuhi, hiki ke lawelawe ʻia ka hopena i ka manawa a ma hope o ka ʻai, akā i kēia hihia pono ʻoe e hoʻokū me ka kō kōpaʻa kiʻekiʻe, ʻo ia ka mea i hoʻonui ʻia aʻe o nā pilikia.
- Mālama i kahi helu o nā papa ʻai, e pale i ka hoʻohana ʻana i ka meaʻai kīkē ʻole.
- Hōʻalo i ka nui o nā meaʻai me kahi kuhikuhi glycemic kiʻekiʻe. E hānai i kahi papaʻai nui ma luna o nā hāmeʻa maloʻo lohi, hoʻohui i ka wikiwiki me nā momona a me nā protein. Wahi a nā maʻi, me ka meaʻai like, e ʻoi aku ka maʻalahi o ke koho ʻana i ka dosis kūpono.
- Mālama i kahi diary a, e pili ana i kāna ikepili, hoʻoponopono i ka manawa o ka manawa o ka Apidra insulin.
Hiki i ka nui o ka lāʻau ke hoʻopiʻi i ka maʻi diabetes i nā ʻōpio. ʻAʻole haʻahaʻa ʻia kēia hui, nā meaʻai maʻamau, nā hana ola. I ka wā ʻōpiopio, e loli pinepine ka hemahema o ka insulin, ʻoi aku ke kiʻekiʻe o ka hypoglycemia, a lōʻihi ka hyperglycemia ma hope o ka ʻai ʻana. ʻO ka hemoglobin maʻamau glycated i nā wā'ōpiopio ma Rusia he 8.3%, kahi mamao loa mai ka pae kiʻekiʻe.
ʻO ka maʻi maʻi a me nā hoʻohaʻahaʻa manaʻo e hana ia i ka wā ma mua
- Ka hana maʻamau o ke kō -95%
- Hoʻokuʻuina o ka pua thrombosis - 70%
- Hoʻopau i kahi puʻuwai ikaika -90%
- Hoʻopau i ke kiʻekiʻe o ke koko - 92%
- ʻO ka hoʻonuiʻana i ka ikehu i ka wā, hoʻomaikaʻi i ka hiamoe i ka pō -97%
Ua hōʻike ʻia nā noiʻi e pili ana i ka hoʻohana ʻana o Apidra i nā keiki i kēia lāʻau ʻai, me Humalog me NovoRapid, e hōʻemi i ka kō. ʻO ka pilikino o ka hypoglycemia like pū. Loaʻa maikaʻi maikaʻi nui Apidra o ka mālama glycemic maikaʻi loa i nā mea maʻi me ka hoʻokiʻu kiʻekiʻe lōʻihi ma hope o ka ʻai ʻana.
Hoʻohana maikaʻi e pili ana iā Apidra
Wahi a Apidra i ka insulin ultrashort. Hoʻohālikelike ʻia me ka hāmeʻa kanaka pōkole, ua komo ka lāʻau lapaʻau i ke koko i 2 mau manawa ka wikiwiki, ʻike ʻia ka hopena o ke kahe ʻana i ke kō. Hoʻonui hou ka hana a ma hope o hoʻokahi hola a me ka hapa hiki i kahi kiʻekiʻe. ʻO ka lōʻihi o ka hana e pili ana i nā hola 4, ma hope o ka manawa e noho ana kahi liʻiliʻi o ka insulin i loko o ke koko, ʻaʻole hiki ke pili i ka glycemia.
ʻO nā maʻi ma ka Apidra he mau hōʻailona maikaʻi o ke kō, hiki iā ia keʻai i kaʻaiʻai liʻiliʻi ma mua o ka maʻi maʻi maʻi maʻi ma ka insulin pondok. ʻO ka lāʻau lapaʻau e hōʻemi i ka manawa mai ka hoʻokele i ka meaʻai, ʻaʻole ia e koi pono i ka mālama ʻana i ka meaʻai a me nā kīmona kauoha.
Inā pili kahi maʻi maʻi i kaʻai haʻahaʻa, ʻoi aku ka wikiwiki o ka hana o ka insulin Apidra, no ka mea ʻaʻole ka manawa hoʻokaʻawale i nā haʻawina koko i ka manawa e hoʻomaka ai ka lāʻau lapaʻau. I kēia hihia, ua hōʻike ʻia nā insulins pōkole akā ʻaʻole ia he ultrashort: Actrapid a Humulin Regular.
ʻŌnaehana hoʻokele
Wahi a nā ʻōlelo kuhikuhi, e lawelawe ʻia ana ka insulin Apidra ma mua o kēlā me kēia pāʻina. He mea makemake ia ma waena o nā papa liʻiliʻi o nā hola 4. I kēia hihia, ʻaʻole pale i ka hopena o nā inikua ʻelua, e ʻae ʻia i ka mana o ka maʻi ʻoi aku ka maʻi maʻamau. Pono e ana ke kukuna ʻaʻole iʻoi aku ma mua o 4 mau hola ma hope o ka ʻōlelo, ka hopena o ka hoʻōla ʻana o ka lāʻau i hoʻopau i kāna hana. Inā ma hope o kēia manawa e hoʻonui ʻia ke kō, hiki iā ʻoe ke hana i nā poplite corrective. Loaʻa i kēlā me kēia manawa o ka lā.
Ke hilinaʻi nei o ka hana i ka manawa o ka hoʻokele aupuni.
| ʻO ka manawa ma waena o keʻeha a me ka meaʻai | Hoʻolaha | |
| Apidra SoloStar | ʻO ka insulin pōkole | |
| he hapa o ka hola i mua o ka papaʻaina | hapalua hola ma mua o ka papaʻaina | Hāʻawi ʻo Apidra i ka mālama maikaʻi o ka maʻi maʻi. |
| 2 mau minuke ma mua o ka papaʻaina | hapalua hola ma mua o ka papaʻaina | ʻO ka hopena o ke kōlooha haʻahaʻa o nā insulins a like me ka like, me ka ʻoiaʻiʻo inā hana ʻo Apidra i ka liʻiliʻi o ka manawa. |
| he hapaha he hola ma hope o ka ʻaina | 2 mau minuke ma mua o ka papaʻaina | |
Apidra a i ʻole NovoRapid
Hoʻohālike kēia mau lāʻau i nā waiwai, nā hiʻohiʻona, nā kumu kūʻai. ʻO ʻApidra lāua ʻo NovoRapid nā huahana o nā mea hana kaulana ma Eulopa, no laila ʻaʻohe kānalua i ko lākou koina. Ua loaʻa i ka insulin i kā lākou mea mahalo i waena o nā kauka a me nā maʻi maʻi.
Nā ʻokoʻa o ka lāʻau lapaʻau:
- ʻAi ʻia ʻo Apidra no ka hoʻohana ʻana ma nā pī e like me insulin. ʻO ka pilikia o ka kahakaha ʻana o ka ʻōnaehana he 2 mau manawa haʻahaʻa ma mua o ka NovoRapid. Ua manaʻo ʻia he ʻano like ʻole ia e like me ke neʻe o ka polysorbate a me ka ʻole o ka zinc.
- Hiki ke kūʻai ʻia ka NovoRapid i loko o nā pahu loea a hoʻohana ʻia i loko o nā penikala syringe i loko o nā waihona he 0,5 o ka nui, ʻo ka mea nui no ka poʻe maʻi maʻi e pono ai nā hapa liʻiliʻi o ka hormone.
- ʻO ka awelika o kēlā me kēia lā ka nui o ka insulin Apidra ma lalo o 30%.
- ʻOi aku kahi lohi a NovoRapid.
Ma waho o kēia mau ʻokoʻa, ʻaʻole ka mea maʻamau e hoʻohana ai - Apidra a i NovoRapid. Hoʻololi i kekahi i ka insulin i kekahi ua noi ʻia no nā kumu olakino wale nō, maʻa mau nā hopena kūlike o ka maʻi.
ʻO Apidra a i ʻole Humalog
Ke koho nei ma waena o Humalog a me Apidra, ʻoi aku ka paʻakikī ʻo ka ʻōlelo ʻoi aku ka mea ʻoi aku ka maikaʻi, ʻoiai ua like like nā lāʻau a me nā manawa a me ka ikaika o ka hana. Wahi a nā maʻi maʻi maʻi, ka neʻe ʻana o ka loli mai kahi insulin i kahi ʻē aʻe me kahi pilikia ʻole, pinepine nā coefficient no ka helu ʻana i loli ʻole.
ʻO nā ʻokoʻa ua loaʻa:
- ʻO ka insulin Apidra he wikiwiki ma mua o kahi Humalog i hoʻopili i loko o ke koko i nā mea maʻi me ka obesity visceral;
- hiki ke kūʻai aku i ka humalog me nā penikala syringe;
- i kekahi mau mea maʻi, nā ʻano like ʻole o nā mākaukau ʻelua o ka ultrashort, aʻo ka lōʻihi o ka insulin me Apidra e emi iki me Humalog.
