ʻO Glurenorm no nā maʻi maʻi - hoʻopau i nā ʻōlelo a me nā loiloi o ka maʻi maʻi

ʻO kekahi o nā ʻelele o kahi pūʻulu nui o nā derogatives sulfonylurea (PSM) ka hoʻolako ʻana i ka waha ma Glurenorm. ʻO kāna mea ikaika, glycidone, he hopena hypoglycemic, hōʻike ʻia no ka maʻi maʻamau ʻo 2. ʻOiai ʻo ka mea ʻemi nui loa, ʻoiai ʻo Glurenorm e like me ka hui pūʻana o kāna hui. Hoʻopau ʻole ʻia ka lāʻau lapaʻau e nā keiki, no laila ke hoʻohana nui ʻia i ka nephropathy maʻi me ke kōkōlohi holomua. Hoʻokuʻu ʻia ʻo Glurenorm e ka māhele Helene o ka hale lāʻau lapaʻau Kelemānia ʻo Beringer Ingelheim.

ʻO ka ʻōlelo kumu ʻo Glurenorm

ʻO Glurenorm no ke kaʻi o ka makahiki 2 o PSM. Loaʻa i ka lāʻau lapaʻau nā mea āpau o ka pharmacological ʻano nui o kēia pūʻulu o nā mākēneko o hypoglycemic:

1. ʻO ka hana nui ma ka pancreatic. ʻO Glycvidone, ka mea ikaika o nā papa Glurenorm, e hoʻopaʻa ai i nā ʻāpana cell pancreatic a hoʻoulu i ka synthesis i loko o lākou. Ke hoʻonui nei i ka hoʻolōʻihi o kēia hormone i ke koko e kōkua i ka pale ʻana i ka kūleʻa o ka insulin, a kōkua i ke kāpae ʻana i ka hilo mai nā ipu koko.
2. ʻO ke hana hou he extrapancreatic. Hoʻonui ka Glurenorm i ka naʻau o ka insulin, e hoʻoneʻe i ka hoʻokuʻu ʻana o ka glucose i ke koko mai ka ate. Hoʻohālikelike ʻia nā maʻi maʻamau ʻo 2 e nā mea nānā ʻole i ka ʻōlelo lipid o ke koko. Kōkua ʻo Glurenorm i kēia mau hōʻailona i kēia mau kuhikuhi, pale aku i ka thrombosis.

Hoʻokomo nā papa i ka pae 2 o ka synthesis o ka insulin, no laila ʻo ka manawa mua ma hope o ka ʻai ʻana i ke kō. Wahi a nā ʻōlelo kuhikuhi, e hoʻomaka ka hopena o ka lāʻau ma hope o hoʻokahi hola, ʻoi loa ka hopena, a i ʻole peak, ua nānā ʻia ma hope o 2 mau hola. Loaʻa ka lōʻihi o ka lōʻihi o ka hana i nā hola 12.

ʻO nā PSM āpau āpau, e komo pū me Glurenorm, he mau ʻaluna nui: hoʻihoʻi lākou i ka synthesis o nā insulin, ʻaʻohe o ka nui o ke kō i loko o nā ipu o ka maʻi maʻi, ʻo ia hoʻi, e hana pū ana me ka hyperglycemia a me ke kō maʻamau. Inā hāʻawi ʻia ka glucose koko i ke koko ma mua o ka mea maʻamau, a i ʻole e hoʻolilo ʻia i ka hana mākala, hoʻomaka ka hypoglycemia. Wahi a nā loiloi o ka maʻi diabetes, nui loa kona pilikia i ka wā o ke kiʻekiʻe o ka lāʻau a me ke kaumaha lōʻihi.

ʻO ka Pharmacokinetics o ka lāʻau

ʻO ka helu nui o nā maʻi me ka maʻi diabetes type 2 ʻo ka makua. Hoʻohālikelike lākou e kekahi hoʻohaʻahaʻa physiological i ka hana excretory o nā keiki. Inā decompensated ka lolo, nui ke maʻi ma nā maʻi nephropathy, a laila pilikia ʻole. ʻO ka hapanui o nā mea hypoglycemic i hoʻopili ʻia e nā keiki, inā ua nele lākou, ʻo ka hōʻiliʻili o ka lāʻau i loko o ke kino e hoʻomaka, ka mea e loaʻa ai ka hypoglycemia koʻikoʻi.

ʻO ka maʻi maʻi a me nā hoʻohaʻahaʻa manaʻo e hana ia i ka wā ma mua

• Ka hana maʻamau o ke kō -95%
• Hoʻokuʻuina o ka pua thrombosis - 70%
• Hoʻopau i kahi puʻuwai ikaika -90%
• Hoʻopau i ke kiʻekiʻe o ke koko - 92%
• ʻO ka hoʻonuiʻana i ka ikehu i ka wā, hoʻomaikaʻi i ka hiamoe i ka pō -97%

ʻO Glurenorm kekahi o nā palekana maikaʻi loa no nā keiki. Hōʻike nā ʻōkuhi no ka hoʻohana ʻana a wikiwiki a piha i ke kīpē, a laila hōʻemi kahe ʻia ʻana e ka ʻūpū e hana ʻole ai i ka metabolites ikaika. ʻO ka hapa nui o lākou, he 95% ka excreted a me nā feces. ʻO ka pepeha ka helu o 5% wale nō o nā metabolites. No ka hoʻohālikelike, 50% o glibenclamide (Maninil), 65% o glyclazide (Diabeton), 60% o glimepiride (Amaryl) e hoʻokuʻu me ka urine. Ma muli o kēia hiʻohiʻona, ʻike ʻia ʻo Glurenorm i ke ʻano o ke koho ʻana no nā maʻi maʻi type 2 me ka hiki ke hōʻemi i ka hana excretory renal.

Nā hōʻailona no ka hoʻokomo

Kauka ke aʻoaʻo i ka hana ʻana me Glurenorm i hoʻopaʻa ʻia me ka maʻi diabetes type 2 paʻa, me ka poʻe maʻi maʻi waena a me nā poʻe maʻi waena.

Ua hōʻike ʻia nā noiʻi i ke kiʻekiʻe nui o ke kō loiloi i ka lāʻau lapaʻau ʻo Glyurenorm. Ke kuhikuhi koke nei ma hope o ka nānā ʻana i ka maʻi maʻi i ka lā a i kēlā me kēia lā a hiki i ka 120 mg i ka maʻi maʻi maʻi, hōʻemi ʻia ka awelika o ka hemoglobin glycated ma luna o 12 mau hebedoma he 2.1%. I nā hui e lawe ana i ka glycidone a me kāna hui analogue glibenclamide, e like me ka helu o ka nui o nā mea i loaʻa i ka uku mellitus maʻi diabetes, kahi e hōʻike nei i ka pili pono o kēia mau lāʻau.

I ka wā hiki ʻole ke inu ʻo Glurenorm

ʻAe nā ʻōlelo no ka hoʻohana ʻana i ka lawe ʻana iā Glurenorm no ka maʻi maʻi i nā maʻi penei:

1. Inā ʻaʻohe mea maʻi o ka maʻi maʻi. ʻO ke kumu paha ke kaohi o ka pancreatic a i ʻole ka maʻi diabetes type 1.
2. I nā maʻi o ka puʻuwai maʻi nui, hiki i ka gphcidone hepatic ka nui o ka metabolly hikiwawe a hōʻiliʻili i loko o ke kino, kahi e alakaʻi ai i kahi overdose.
3. Me ka hyperglycemia, ke kaupaona ʻia e ka ketoacidosis a me nā hoʻopihapiha - precoma a me coma.
4. Inā loaʻa ka maʻi i ka hypersensitivity i glycvidone a i ʻole PSM ʻē aʻe.
5. Me ka hypoglycemia, ʻaʻole hiki ke inu i ka lāʻau a hiki i ka hoʻōla ʻana o ke kō.
6. I nā kūlana koʻikoʻi (maʻi koʻikoʻi, hōʻeha, nā kaiāulu), glurenorm is a wā pōkole ke hoʻololi i ka insulin.
7. I ka wā hapai a i ka wā o ka hepatitis B, pāpā ʻole ʻia ka lāʻau, ʻoiai ua komo ka glycidone i ke koko o kahi keiki a hoʻopilikia i kona hoʻomohala ʻana.

ʻO nā maʻi Holoal e hoʻohālikelike ai i nā maʻi thyroid e hiki ke hoʻololi i ka hana o ka insulin. Hōʻike ʻia kēlā mau mea maʻi i nā lāʻau lapaʻau ʻaʻole e kumu i ka hypoglycemia - metformin, glyptins, acarbose.

ʻO ka hoʻohana ʻana i ka lāʻau lapaʻau Glurenorm i loko o ka waiʻona makeke nui me ka hoʻohuihui koʻikoʻi, piʻi ʻole kū mai i ka glycemia.

Nā Mana Kūʻai

Loaʻa ka Glurenorm i kahi waihona o 30 mg wale nō. Hōʻalo nā papa, no laila hiki ke hoʻokaʻawale iā lākou i loaʻa ka hapalua o ka nui o ka waiū.

ʻĀ ʻia ka lāʻau lapaʻau ma mua koke o kahi ʻai, a i kona hoʻomaka. Ma kēia hihia, e ka hopena o ka ʻahaʻaina a i ʻole ma hope o ka manawa, e hoʻonui ʻia ka kiʻekiʻe o ka insulin ma kahi o 40%, e alakaʻi ai i kahi kahe o ka kō. ʻO ka hoʻohaʻahaʻa ʻana ma ka insulin i ka wā e hoʻohana ai iā Glyurenorm i kokoke i ka physiological, no laila, haʻahaʻa ka hoʻohaʻahaʻa o ka hypoglycemia. Hoʻomaopopo ke aʻo e hoʻomaka me ka hapalua o ka pail i ka kakahiaka kakahiaka. A laila e hoʻonui mālie ʻia ka nui a hiki i ka uku ʻana no ka maʻi diabetes. ʻO ka manawa ma waena o ka hoʻoponopono o ka hoʻoponopono ma ka liʻiliʻi he 3 mau lā.

Mai kiʻi i ka meaʻai ma hope o ka lawe ʻana i ka lāʻau. Pono nā huahana i nā kalapika, maikaʻi loa me index glycemic haʻahaʻa. ^ E Ha yM. ʻAʻole ke kāpae i ka hoʻohana ʻana iā Glenrenorm i ka meaʻai a me ka hoʻomaʻamaʻa mua ʻana. Me ka hoʻohana ʻole paʻa ʻana i nā kao a me ka hana haʻahaʻa, ʻaʻole hiki ke hāʻawi ʻia ka lāʻau lapaʻau i ka uku no ka maʻi maʻi i ka hapa nui o nā maʻi.

Hoʻouna ʻia e Glyurenorm me ka nephropathy

ʻAʻole koi ʻia ka hoʻoponopono ʻana o Glurenorm no ka maʻi ʻeha. No ka mea ka nui o ka glycidone e kaʻe ʻana i ka ʻōpū, ʻaʻole i hoʻonui ka maʻi maʻi me ka nephropathy i nā maʻi o ka hypoglycemia, e like me nā lāʻau lapaʻau.

Hōʻike ka hōʻike o ka hōʻike hōʻike ma mua o nā hebedoma 4 o ka hoʻohana ʻana i ka lāʻau lapaʻau, hōʻemi ka proteinuria me ka maikaʻi o ka mālama maikaʻi i ka maʻi mellitus, a hoʻomaikaʻi hou i ka urine reabsorption. Wahi a nā loiloi, ua kuhikuhi ʻia ʻo Glurenorm ma hope o ke hoʻololi ʻana i ka kidney.

Hoʻohana no nā maʻi ate

Ke papa aku nei ia i ka lawe ʻana iā Glurenorm i ka huhū palupalu. Eia nō naʻe, aia kahi hōʻike e mālama pinepine ʻia ka glycidone i nā maʻi o ka naʻau, ʻoiai ʻaʻole i hiki ke hōʻemi ʻia ka hana ʻana, a ʻaʻole i hoʻonui ʻia ka hopena o nā ʻaoʻao. No laila, hiki ke koho iā Glyurenorm i kēlā mau maʻi maʻi ma hope o ka hoʻokolokolo pono ʻana.

Hoʻohui hui

I nā ʻōlelo kauoha no Glyurenorm, ʻae ʻia ka lāʻau e lawe wale i ka metformin. Wahi a nā loiloi, hele maikaʻi ka lāʻau lapaʻau me nā acarbose, DPP-4 inhibitors, insulin. No ka pale ʻana i ka overdose, ua pāpā ʻia ʻo Glyrenorm e inu i ka manawa like me nā PSM ʻē aʻe.

Nā hopena hopena, ka hopena o ka overdose

ʻO ke alapine o nā hopena ʻokoʻa ʻole i ka wā e lawe ai i ka lāʻau lapaʻau Glurenorm:

I nā hihia kūʻokoʻa, he mau hewa no ka haki o ka hua bile, urticaria, kahi hoʻemi ʻana i ka pae o ka leukocytes a me nā granulocytes i loko o ke koko.

I ka hihia o kahi overdose, kiʻekiʻe ke kumuhana o ka hypoglycemia. Hoʻopau iā ia ma o ka huki waha a i ʻole ka intravenous glucose. Ma hope o ka hoʻāla ʻana i ke kō, hiki iā ia ke hāʻule pinepine pinepine a hiki i ka lawaiʻa ʻana mai ke kino.

Hoʻohui nūhou

Hiki ke loli ka hopena o Glenrenorm me ka mālama like ʻana me nā hana ʻē aʻe.

• nā mea hoʻohālikelike waha, nā hōʻeuʻeu o CNS, nā steroid a me nā hormone thyroid, ka waikama nikotinika, chlorpromazine hoʻonāwaliwali i kona hopena;
• kekahi mau NSAID, antibiotics, antidepressants, antimicrobials, Coumarins (acenocoumarol, warfarin), thiazide diuretics, beta-blockers, ethanol hoʻonui i ka hopena o ka lāʻau.

Nā ʻōlelo kikoʻī

Ke lawe nei iā Glyurenorm, koi pono i nā ʻōlelo olakino e pili ana i ka hana maʻamau o nā mea laʻa. ʻO ka mālama ʻana i ke kino, kūpono pono i ka meaʻai i ʻōlelo ʻia ai, pono e nānā pono ai i ka hana o ke keiki.

I ka hihia o nā hopena ʻaoʻao, pono e kūkākūkā ʻoe i ke kauka e hoʻoponopono i ka pilikia o ka pono e hoʻololi i ka lāʻau lapaʻau.

I nā hana e koi ai i ka piʻi nui ʻana o ka manaʻo (ka holo ʻana, ka hana ʻana me nā hāmeʻa, ma ke kiʻekiʻe, a me kekahi mea). ʻOi ka ulu o ke kōpoki hāʻule i ke kiʻekiʻe ma kahi o ka hoʻonui ʻana i ka nui.

ʻO nā kumu kūʻai a me nā mea hoʻohuli Glurenorm

ʻO ke kumu o kahi pākeke me 60 mau papa o Glyurenorm ma kahi o 450 mau rubles. ʻAʻole i waiho pū ʻia ka waihona glycidon ma ka papa inoa o nā lāʻau lapaʻau ikaika, no laila e hiki ʻole ke loaʻa iā ia no ka manu ʻole.

ʻAʻole loaʻa kahi kikowaena kikoʻī me nā mea hana like ma Rusia. Ke hana nei kēia hana no ka hoʻopaʻa inoa inoa no ka lāʻau lapaʻau Yuglin, ka mea hana a Pharmasynthesis. Ua hōʻoia ʻia ke koi kaulike o Yuglin a me Glyurenorm, no laila, ma hope koke e manaʻo ʻia nei e kūʻai ʻia aku ma ke kūʻai aku.

I nā maʻi maʻi palaka me nā keiki olakino, hiki i kekahi PSM ke hoʻololi i Glurenorm. Ua pālahalaha lākou, no laila ke maʻalahi ka koho i kahi lāʻau lapaʻau kūpono. Hoʻomaka ka kumukūʻai o ka mālama ʻana mai 200 rubles.

I nā hana ʻole, ua kauoha ʻia ka linagliptin. Aia kēia ʻano hana i loko o ka hoʻomākaukau ʻana o Trazhent lāua me Gentadueto. ʻO ke kumu kūʻai o nā papa i ka mahina o ka mālama ʻana mai 1600 rubles.

Nā Hōʻike Kokua