ʻO ke ʻano ma ke kīʻaha koko o nā kaʻe o ka puni o nā hāmeʻa e hōʻino ana i ke kahe koko maʻamau he maʻi paʻakikī a he mea maʻamau loa ia.
Ke hakakā nei i ka hoʻopuka nui ʻana o nā māho koko, ua hoʻohana ʻia nā lāʻau like ʻole e hana ma ka antithrombin protein protein.
ʻO kekahi o nā lāʻau lapaʻau ka mea maʻamau loa ʻo Fraxiparin, a me kāna mea he nui no ka hoʻohuli. He aha nā analogues o Fraxiparin e hoʻohana ʻia ai i ka lāʻau lapaʻau?
Inoa Kūʻai ʻole honua
ʻO Fraxiparin ka inoa inoa ʻano, i mea e hōʻike ai i ka kikoʻī o ka lāʻau lapaʻau, ʻo Nadroparin calcium, ʻo ka inoa Latin inoa ʻo Nadroparinum calcium.
ʻO ka lāʻau lapaʻau Fraksiparin 0.3 ml
ʻO nā inoa kālepa like ʻole o nā lāʻau lapaʻau, i hui pū ʻia e ka inoa inoa hoʻokahi, i ka hopena like i ka kino o ke kanaka i ke ʻano o nā hiʻohiʻona a me ka ikaika.
Hoʻohui ʻia i ka inoa, ka ʻokoʻa ma waena o nā lāʻau lapaʻau e ʻokoʻa ana e ka mea hana me ka mea i loko o ka make, a me ka hoʻonohonoho ʻana o nā mea hoʻowalī a me nā mea hoʻonaninani a me ka kūlohelohe i ka lāʻau a pau i loko o ka lāʻau.
Mea hana
ʻO ka lāʻau i kapa ʻia ʻo Fraxiparin i hana ʻia i Farani i nā hale hana ʻoihana ma ke ʻano lāʻau lapaʻau nui lua loa i ʻEulopa, GlaxoSmithKline, headquartered ma Lākana.
Eia naʻe, he mea kūʻai nui kēia lāʻau lapaʻau, no laila ua hoʻolālā ka lāʻau lapaʻau i kāna mau helu he nui.
ʻO nā pānaʻi māmā maʻamau ka maʻamau:
- ʻO Nadroparin-Farmeks i hana ʻia e Farmeks-Group (Ukraine);
- ʻO Novoparin i hana ʻia e Genofarm Ltd (UK / China);
- Flenox i hana ʻia e PAO Farmak (Ukraine);
Hoʻohana ʻia nā huahana like e kekahi nui o nā hui kūloko ʻenehana a me ʻEulopa. Wahi a nā hopena ma ke kino, ua hui kūʻokoʻa lākou.
Pākuʻi helu
Loaʻa ka lāʻau lapaʻau i ke ʻano o ka hopena no ka inikua. Mākaukau i ka mea hana a me nā ʻano, he nui nā koho kapu.
ʻO ka maʻamau maʻamau ka nui o nā 0.2, 0.3, 0.6 a me 0.8 milliliters. Hiki ke hāʻawi ʻia ka hale hana ʻoihana o ka hui Kelemānia ʻo Aspen Pharma i loko o kahi waihona ʻo 0.4 milliliters.
ʻO waho, ka hopena ka wai o ka waile-ole aʻaila, ʻonanika a ʻulaʻula paha. He ʻano huakaʻi ka lāʻau lapaʻau hoʻi. ʻO ka mea kūʻokoʻa o Fraxiparin ka mea i hāʻawi ʻia ʻole ʻia ka hopena i nā ampou e ʻike ʻole ʻia e ko mākou mea kūʻai, e koi ana i ke kūʻai ʻana i kahi syringe hiki ʻole i ke ʻano kūpono a me kekahi mau kahakaha ʻana ma mua o ka hoʻonā ʻia ʻana.
E kūʻai aku ʻia ka lāʻau lapaʻau i nā injectors syringe kūikawā, paʻa loa no ka hoʻohana ʻana. I mea e hoʻokomo ai, e wehe wale i ka pale pale mai ka pūaiki a kau ma ke piston.
ʻO ka mea waiwai nui
ʻO ka manaʻo o ka inoa inoa ma lalo nei e hana ʻia ai ka lāʻau lapaʻau e nā mea hana, ʻo kāna ʻano hana i ka haʻahaʻa o ka heparin.ʻO kēia polysaccharide hoʻokaʻawale ʻia mai ka puʻuwai he anticoagulant maikaʻi.
Ke hoʻomaka nei i loko o ke koko, hoʻomaka ka heparin e nakinaki i nā pūnaewele cationic o tri-antithrombin.
A ke kumu, ua hoʻololi nā molekele antithrombin i kā lākou mau waiwai a hana i nā enzyme a me nā protein e pili ana i ka hoʻoulu ʻana o ke koko, inā pono, ma ka thrombin, kallikrein, a me nā proteine serine.
I mea e hiki ai i nā mea ke hana ikaika a wikiwiki hou, hoʻokaʻawale ʻia ka molekela polymer "lōʻihi" i loko o nā mea pōkole e ka depolymerization ma lalo o nā kūlana kūikawā i nā mea paʻakikī.
ʻO nā hui hoʻohālike
ʻO ka lāʻau Fraxiparin ka mea hoʻohana pinepine ʻia i ka wā hāpai.
ʻOiaʻiʻo, i kēia manawa, ma muli o nā loli i ke ʻano o ka hormonal, nā ʻano koikoi o ka ulu ʻana o ke koko, hiki iā ia ke alakaʻi i ka kaumaha thrombotic. He aha nā kikowaena o ka lāʻau lapaʻau e hiki ke lawe ʻia i ka wā e lawe ana i ka pūpū?
Ua hoʻohana pinepine pinepine ʻia ʻo Angioflux - kahi hui like o ka heparin-like fraction, ka mea i lawe ʻia ʻia mai ka mucosa o ka ʻili kuʻuna o nā puaʻa kūwaho. ʻO nā capsules no ka hoʻokele waha, a me nā mea hopena hou aku e pono ai no ka ʻaina.
ʻO kekahi mea hou aku i hoʻohana nui ʻia i ka wā hāpai a hepatrombin. Wahi a ka hoʻopili ʻana o ka mea ikaika, he hui kūlike ʻo Fraxiparin, eia naʻe, ʻokoʻa ia i loko o ka pauna i ka dosage. ʻAʻole i like me ka wā ma hope, loaʻa nā hepatrombin i ke ʻano o ka hana poni no ka hoʻohana ʻana i waho.
Hepatrombin Kahawaiina
ʻO ka hope, ʻo ka hoʻomākaukau ʻana o ka Wessel Duet F, he loko pū me ka polysaccharides - glycosaminoglycans, he hopena like hoʻi me Fraxiparin. ʻO kā kā lākou keʻena hana i ke kīnā i ke kumu X o ka coagulability o ke koko me ka hoʻolaʻa pinepine ʻana i nā prostaglandins a me kahi laʻa o ka fibrinogen i loko o ke koko.
Nā kikowaena maʻalahi
ʻO ka mea pōʻino, e like me ka hapa nui o nā huahana Europa, he nui ke kumukūʻai o Fraxiparin. Eia nō naʻe, aia nā mooolelo maʻalahi loa e hiki ai i ka pale pono a me ka mālama ʻana i nā hōʻike thrombotic a mālama i ke kālā. ʻO nā mea haʻalulu loa o nā lāʻau lapaʻau ka lāʻau lapaʻau i hana ʻia ma Kina, India a me CIS.
Paina Enoxaparin-Pharmex
Loaʻa ka lanakila ma ka hoʻokomo ʻana e kahi lāʻau lapaʻau ma lalo o ka inoa kālepa inoa Eneksaparin-Farmeks o Ukraine kahi. I ka mākaukau ʻana o ka ʻoihana "Pharmex-Group", ʻo ka mea hoʻohana koʻikoʻi ka mea hoʻohui kai, ʻo ia hoʻi, disunited, heparin.
ʻAʻole iʻoi aku ke kālā ma mua o Enoxarin i hana ʻia e Biovita Laboratories - kahi hui lāʻau lapaʻau nui nui o India. Hāʻawi ʻia ia i loko pū me kahi mea hoʻokaʻawale ʻē aʻe a loaʻa pū kahi ʻano hana like ʻole - ka hoʻohui kalepona o ka heparin "pōkole".
ʻO kahi mea makemake maʻamau no Fraxiparin kahi lāʻau i kapa ʻia ʻo Clexane. Hoʻolako ka lāʻau lapaʻau Farani i ka hana, e hōʻoia ai i ka kiʻekiʻe o ka lāʻau lapaʻau a me ka palekana o kāna kūleʻa.
ʻOkoʻa ʻana ka Fraksiparin mai Kleksan
Hoʻohālikelike ʻia ka Clexane e ke kumukūʻai ʻoi aku ke kiʻekiʻe, akā ke noʻonoʻo ʻia nei e kekahi mau hoʻomaʻamaʻa ʻana i nā kauka i manaʻo ʻia ʻo ia ka mea maʻalahi a maikaʻi ka anticoagulant i ka wā hāpai.
ʻO ka maʻalahi o ka hoʻohana ʻana o Clexane he lōʻihi, pili i Fraxiparin, hopena i ke kino.
Wili Clexane
Wahi a ka hoʻomaʻamaʻa maʻamau, pono ia e hoʻokō iā Fraxiparin pālua i kēlā me kēia lā. I ka manawa like, loaʻa ʻo Clexane i kahi hopena i loko o 24 mau hola, e hōʻemi ana i ka nui o nā inikini ma ka hapalua.
Hāʻawi ʻia e lawe ʻia kēia lāʻau lapaʻau i kahi manawa lōʻihi, ʻo ka hōʻemi i ka helu o kēlā me kēia lā o ka injections e makemake ʻia e pili ana i ka hōʻoluʻolu o ka mea hoʻomanawanui a mālama pono.
Inā ʻaʻole, ʻaʻole like loa kēia mau lāʻau lapaʻau a ʻokoʻa ʻole ma ka ʻano o ka hoʻokuʻu, a i ʻole i ka mea ikaika, a i ʻole ka hopena o ke kino i kā lākou luna.
ʻOi aku ka maikaʻi?
Fraxiparin a Heparin
ʻO kekahi o nā lāʻau lapaʻau mua i hoʻohana ʻia no ka hōʻeuʻeu koko nui ʻo Heparin, kahi lāʻau lapaʻau e loaʻa ana i ka sodium heparin me kahi mea ikaika.Eia naʻe, i kēia manawa e hoʻonui nui ia e Fraxiparin a me kāna mea kikowaena.
ʻO ka manaʻo e hele ʻo Heparin i ka pāpaʻi placental a hiki i ka hopena maikaʻi ʻia i ka maʻi hānai.
Wahi a nā haʻawina, ʻaʻole hōʻike ʻo Fraxiparin lāua ʻo Heparin i ka hiki ke komo i ka plasenta a he hopena maikaʻi ʻole paha ma ka fetus inā he nui wale ka dosage i ʻae ʻia.
ʻO ka laha o Fraxiparin i ka hana olakino hou e hoʻākāka wale ʻia e nā mea maʻalahi o kona hoʻohana ʻana - inā ʻaʻole i loaʻa nā hopena kūlike i ka lāʻau lapaʻau.
Fraxiparin a i ʻole Fragmin
ʻO Fragmin, e like me nā lāʻau lapaʻau'ē aʻe i loko o ka hui, aia kahi heparin hoʻokaʻawale. Eia nō naʻe, hoʻohana ʻia ʻo Fragmin i mea maʻamau coagulant, ʻaʻole like me Fraxiparin, i hoʻolālā ʻia no ka hoʻohana ʻana i ka wā hāpai.
Wili a Fragmin
Inā loaʻa ka hopena o hope i kahi pūleo calcium o ka mea ikaika, a laila loaʻa iā Fragmin i ka paʻakai sodium o ka heparin polymerized. Aia nā manaʻo ma kēia hiʻohiʻona, ʻo Fragmin ka hopena koʻikoʻi ma ke kino.
Ma ke kaʻina hana o kēia lāʻau lapaʻau, ʻoi aku ka nui o ke kahe koko ʻana mai nā moku koko manawaleʻa. Ma keʻano pilikino, hiki i ka hoʻohana ʻana iā Fragmin ke hana i nā noseble maʻamau, me ka hoʻokaʻawale ʻana i nā gums o nā maʻi.
Nā wikiō pili
Pehea e hana ai i kahi maʻi subcutaneous o Clexane:
Ma ka holoʻokoʻa, aia ma kahi o ʻinikolē kaila o Fraxiparin, i ʻokoʻa i ke kumukūʻai maikaʻi loa a i ʻole i ka hana lōʻihi ʻana, a ke hāʻawi nei ʻoe e mālama i ke kālā ma o ka pale ʻana i ke kuʻuna o ka lawaiʻa koko i ʻike ʻia i ka wā o ka hapai a me nā maʻi enzymatic.
