ʻO kahi hanauna hou o nā lāʻau maʻi maʻi type 2 e hoʻomaʻamaʻa i ka mea maʻi a kōkua i ka mālama ʻana i nā momona koko. Ke koho ʻole o ka lapaʻau ka mea maʻamau, ʻaʻole ia he hana maʻalahi, no laila, e hana pono ka endocrinologist me ia. He mea weliweli loa ke kuhikuhi i ka lāʻau lapaʻau ma kāu pono ʻole me ke kauka, no ka mea, he loko ʻino kēia a me ka holomua o ka maʻi.
ʻO nā pahuhopu nui o ka lāʻau lapaʻau
Loaʻa i kēlā me kēia lāʻau lapaʻau kekahi hopena ʻaoʻao, no laila ʻaʻole lākou i kuhikuhi me ka ʻole o ka hemahema. Aia ma muli o nā ʻano pilikino o ka papa o ka maʻi diabetes, nā lāʻau lapaʻau me nā ʻano hana ʻokoʻa o ka hana e hiki ke ʻōlelo ʻia i ka mea maʻi. Akā ʻo ka pahuhopu nui o ka lawe ʻana i kekahi lāʻau lapaʻau no ka maʻi diabetes type 2 e hoʻohaʻahaʻa i ka glucose koko.
Eia kekahi, he mea nui ia e pale i ka mea maʻi e hoʻomohala i nā hoʻopiʻi e like me ka hypertension arterial, hōʻeha hōʻeuʻeu, maʻi syndrome diabetes and neurological pathologies. A hiki wale nō kēia me nā pae meli maʻamau.
ʻO kaʻoiaʻiʻo, ʻaʻole i loaʻa nā hopena ʻekepili hou i nā hopena ʻokoʻa e like me kā lākou mea e hoʻohana mua ai ma mua. Hoʻomau mau nā Endocrinologists i ke koho i kahi lāʻau i kūpono i ka mea maʻi e like me ka mea kūpono a hiki i ka hopena kūpono ʻole. E koho i ka lāʻau lapaʻau ʻoi aku ka maikaʻi, pono i ka mea maʻi ke loaʻa i kahi ʻano o ke ʻano maʻi biochemical i loaʻa i ke kauka i kahi manaʻo manaʻo o ke ʻano o ka pancreas a me nā mea kūwoko kekahi.
Biguanides - nā lāʻau lapaʻau kūpono a me nā kūpono
Aia ʻo Biguanides i kahi lāʻau lapaʻau kaulana loa i kuhikuhi ʻia no ka maʻi maʻi type 2. ʻAʻole lākou e hoʻowalewale i ka pancreas e hana hou i ka nui o ka insulin, akā hana maoli lākou i ka pae o ka bioavailable insulin e inert (i.e., bound, ʻaʻole hiki ke hana i kāna hana). Ma muli o kēia, ua pono ka ulu ʻana o nā kiko i ka insulin, a me ka emi ʻana o ke kō koko.
Hoʻomaʻamaʻa nā lāʻau lapaʻau i kēia hui i ka metabolism a hoʻolaha i ka hoʻolilo kaumaha. Hoʻomau ka Biguanides i ka pale ʻana i ka insulin i ka pae o ka ate a hoʻoponopono i nā metabolid lipid. Hāʻawi kēia mau lāʻau lapaʻau i ka hoʻemi ʻana i ke kaumaha o ke kino o ke kanaka, no laila, ua hoʻoikaika pono lākou i nā mea maʻi me ka momona.
ʻO nā mākaʻi kaulana loa o kēia ʻano ʻōlelo lapaʻau ʻo Siofor a me Glokofage. ʻO lākou ka metmforfin. Loaʻa kēia ʻano momona i nā dālā mau o ka lāʻau lapaʻau, ʻo ia hoʻi, nā lāʻau lapaʻau lōʻihi. Aia kēia me Siofor Long a me Metadiene. Hoʻohana lākou iā lākou ʻaʻole i nā hopena koʻikoʻi, a hiki ke hoʻokaʻawale ʻia nā mea hōʻona wale ʻole mai ka pūnao ʻana.
ʻO ke kuhikuhi ʻana i ka insulin no ka maʻi type 2 he ʻano paʻakikī a hiki nō paha. ʻO kekahi manawa kūpono kēia no ka mālamaʻana i ke olakino o ka mea maʻi.
Pili anei ka hoʻohana ʻana i nā derivatives o ka sulfonylurea?
Ke hoʻoikaika nei kēia mau lāʻau iā lākou nā cell beta pancreatic e hana i nā insulin, e hōʻemi i ke kō koko. E hele koke mai ka hopena o ka lawe ʻana i kēia mau panana a hoʻomaikaʻi nui ʻia ma mua o nā lāʻau lapaʻau ʻē aʻe e hoʻohaʻahaʻa i ka glucose.
Hoʻopili kēia me Glibenez, Glucotrol, Minidiab, etc. Akā ʻo kekahi mau hopena maikaʻi ʻole a me kahi ʻoihana kikoʻī o ka hana i lilo ʻole iā lākou i ka mea "koho" koho no ke ʻano maʻi type 2.
Inā ʻaʻole i kūpono ka helu ʻana o kēia lāʻau lapaʻau, e hana nā cell pancreatic i hana no ka mea pono, a, ma hope, makemake kekahi mea maʻi me ka maʻi type kīnā i ka injections o ka insulin. Pono ke koho i ka pauna intake i ka mea nui i ka hana beta-cell ka nui i ka manawa no nā hola ma hope o ka manawa e ʻai ʻia ai ke ʻano o ke kō o ke koko. No ka hoʻokō pono ʻana i nā hana pono, e kuhikuhi ʻia kēia mau lāʻau lapaʻau i hui pū me nā lawena ʻē aʻe. I ka wā o ka mālama ʻana me nā derivatives sulfonylurea, pono i ka mea maʻi i kēlā me kēia manawa i ka hoʻokaʻina koko biochemical e nānā i ke ʻano o ka pancreas.
ʻO nā hopena ʻaoʻao:
Hoʻomaopopo o nā maʻi diabetes type 2 i nā wahine- hypoglycemia nui;
- ʻo ka waiwai kaumaha;
- hemo wale, he luaa
- nā pepeke
- i loko o nā kahe koko.
ʻAʻole pono kēlā hana e neʻe koke koke, akā inā loaʻa nā hōʻailona kānalua a i ʻole ke ʻano o ka hōʻino i ke olakino maikaʻi, pono koke ka mea maʻi e ʻike i ke kauka. ʻO ka lawe ʻana i kēlā mau peni ma kahi kūpono kūpono a ma lalo o ka mākaʻi a endocrinologist e hana ʻino ʻole ʻia, akā, i kekahi manawa, pono ka maʻi maʻi e hoʻoponopono ʻia.
ʻO nā mea hoʻohiwahiwa o kekahi mau enzyme e ola maikaʻi akā pono nā lāʻau lapaʻau nui
ʻO nā Enzymes nā meaola mauola e hoʻolaʻa ai i nā ʻano biochemical i loko o ke kino. ʻO nā inhibitors kahi hoʻohuiʻana i ka lohi i ka hele ʻana o kēia mau hopena. Ma nā kaila o ka kalaiwa, nui nā enzyme e kuleana no ke kaʻina wāwahi i nā hoʻokaʻamae paʻakikī, ma waena o alpha glucosidase a me dipeptidyl peptidase-4 hiki ke hoʻomaopopo.
Hoʻololi ka lohi o nā glucose glucosidase i ka hoʻokaʻawale ʻana o nā palakū paʻakikī a me ko lākou komo ʻana i ka iwi liʻiliʻi. Ma muli o kēia, haʻahaʻa ka pae o ka glucose i loko o ke koko a ʻaʻohe koi koi i ka waiwai. Ma hope o ka ʻai ʻana o ka mea maʻi i ka ʻai me nā mea laʻa paʻakikī i ka hoʻopiha ʻana, ma muli o ka hana a ka lāʻau lapaʻau, pono hou ke ʻano o ka manawa e wāwahi ai a komo i ke kahe koko. ʻO nā mea nui a kēia ʻano hui o nā lāʻau lapaʻau:
- acarbose ("Glucobay");
- miglitol ("Diastabol");
- voglibose ("Voxide").
Hoʻohana ʻē aʻe nā Dipeptidyl peptidase-4. Hoʻonui lākou i ka hana o ka insulin ma muli o ke kaila o ka glucose. Hāʻawi ka lāʻau lapaʻau i ka hoʻōla ʻana o ka hāmeʻa kūikawā - incretin, ma lalo o ka mana o nā peka pancreatic beta e hana hou aku i ka ikaika. ʻO nā hui o kēia kuʻina ke komo i nā lāʻau lapaʻau ʻO Lonvia a me Galvus.
Hoʻohana maikaʻi ʻia nā inhibitor Enzyme e ke kino, akā ke kumu nui, no laila ʻaʻole ia e like me ka biguanides
ʻO Glitazones - nā lāʻau lapaʻau hou a me ke kūpono
ʻO kahi Glitazones kahi ʻano hou o nā lāʻau lapaʻau no ka mālama ʻana i ka maʻi maʻi. Ua hoʻolālā ʻia lākou a hoʻokomo ʻia i loko o ka hoʻomaʻamaʻi olakino mai ka makahiki 1997. Kūkulu ʻia kā lākou hana i ka hoʻomaikaʻi ʻana i ka ʻike o nā kao i ka insulin. Hoʻohana nui kēia hopena i nā ʻiʻo o ke kino a me nā ʻiʻo adipose, i kahi liʻiliʻi i ka ate. ʻO nā lāʻau lapaʻau e hoʻohaʻahaʻa i ka pale ʻana i ka insulin a no laila hāʻule ka nui o ke kō koko koko.
ʻAʻole loli nā lāʻau i kēia pūʻulu i ka hana o nā peka beta pancreatic. Ke mau nei ka hana o ka insulin i ka pae like ma mua o ka lāʻau lapaʻau. No laila, hiki ke hoʻohana ʻia kēlā mau lāʻau lapaʻau no kēlā mau mahele o nā mea maʻi nona ka pancreas e hana i kahi hormone e hōʻemi i ke kō i ka nui.
Ma kēia ʻano hana, ʻike ʻia nā ʻano ʻelua o glitazones e mālama i ka maʻi maʻi:
- rosiglitazone ("Avandia");
- pioglitazone ("Actos").
Aia kahi kolu o kahi kolamu - thioglitazone, akā i kēia lā ʻaʻole ia i hoʻohana ʻia ma muli o nā hopena hopena o ka puhipuhi i ka ate. Hiki i kēia ʻano o nā lāʻau lapaʻau ke hoʻemi i nā pae haʻahaʻa e 1-3 mmol / L; hoʻohana pinepine ʻia i ka hui pū me biguanides a me ka sulfonylureas.
Meglitinides - nā lāʻau hou akā ua kūʻai ʻia
ʻO Meglitinides kekahi o nā lapaʻau hou hou no ka maʻi diabetes type 2. Pono lākou e lawe i kekahi mau minuke ma mua o ka papaʻaina, ʻoiai e hoʻonui ana i ka hana insulin. ʻO ka hoʻohiwahiwa o nā papa ke alakaʻi i ka hoʻonui ʻana o ka insulin i ka manawa pōkole i ka pane ʻana i ka nui o ke kao o ka glucose i ke koko.
Ma muli o ka hana pono ʻana o ka meglitinides no ka manawa pōkole, lawa kēia e hoʻemi ai i ke kōpaʻa ma hope o ka ʻai ʻana me ka ʻole e hoʻopiʻi i nā hopena koʻikoʻi a me ke kaumaha o ka pancreatic.
Hoʻopili kēia me nā mea kanu e like me Starlix a me Novonorm. ʻAʻole e like me derivatives sulfonylurea, hana koke kēia mau lāʻau i ka manawa a ma hope o ka ʻai. Inā no kekahi kumu kahi hānai ʻia e kahi maʻi maʻiʻai ʻole, ʻaʻole pono ʻoe e inu i ka pā. ʻAʻohe hopena lōʻihi o ka lāʻau lapaʻau. He mea kūpono loa kēia no ka poʻe maʻi, no ka mea ke hiki iā lākou ke alakaʻi i ke ʻano olaola a ʻaʻole i hoʻopili ʻia me kahi papaʻaina maopopo ʻole i kekahi mau hola (ʻoiai naʻe, ʻoiaʻiʻo ka wikiwiki me ka maʻi maʻi maʻi).
Loaʻa iki nā hopena ʻaoʻao, ʻo ka koʻikoʻi loa ka mea hypoglycemia. ʻO ka kumu, ke hoʻopili ʻia nei kēlā me kēia me ke keu nui i ʻōlelo ʻia ʻole ʻia a i ʻole ʻia ka ʻai. ʻO Meglitinides nā lāʻau lapaʻau loa. No ka mālamaʻana i nā maʻi maʻi me ka maʻi type 2, ua hoʻohana nui ʻia lākou me ka hui me ka metmorphine.
ʻO nā lāʻau hoʻohui
I nā hui kālā no nā mellitus type 2, ua loaʻa i nā papa he nui i hoʻokahi manawa. Hoʻokomo ʻia kēia mau lāʻau i nā lāʻau lapaʻau me nā inoa kālepa e hiki mai ana:
- Kūkākūkā;
- Kuʻi;
- Kuʻunaʻi;
- Metglib
- "Janumet";
- Glimecomb.
Hoʻololi pinepine ʻia nā lāʻau hoʻohui i nā hihia inā ʻaʻole kōkua nā lāʻau lapaʻau hoʻokahi i ka mea maʻi. Inā poina ka mea maʻi e lawe i nā papa he nui i ka lā, e pili ana i nā papa like ʻole o nā ʻano mea, hiki ke ʻōlelo ʻia nā lāʻau lapaʻau. Ua kiʻekiʻe ke kumukūʻai o ia mau lāʻau, a ua hoʻāpono ʻia kā lākou kumu inā ʻaʻole nā loiloi monocomponent hiki ke hāʻawi i ka pae kōmaʻa o ka ʻai. ʻAʻole pono kēia no kēia mea, no ka mea, ʻoi aku ka maikaʻi o ka lāʻau hou no ka non-insulin-dependence maʻamau.
Ma kahi o ka lawe ʻana i nā lāʻau lapaʻau no ka maʻi maʻi maʻi nui, pono no ka mea maʻi e hahai i kahi kīʻai a mai poina e pili ana i ka hana pilikino. Inā pili ke ʻano o ka mea maʻi i ka mālama ʻana i ka insulin, pono ʻoe e ʻae koke a ʻaʻole e hoʻāʻo e hoʻololi i kekahi mea. ʻO ka maʻamau, me ka maʻi maʻamau o ka lā 2, he hana iki kēia e pono ai e hoʻoponopono i nā hōʻailona nui o ka metabolism ka mea hoʻonui a mālama i ka olakino maikaʻi.
