ʻO ka maʻi Lada maʻi

ʻO kēia manawa aku, ua mahele ʻia ka maʻi diabetes i ka mua a me ka lua, akā, no ka hopena o ka noi ʻana o ka noiʻi, ua loaʻa nā ʻano hou, ʻo ia kekahi o ka maʻi Lada maʻi (ʻo ka LADA diabetes). E pili ana i ke ʻano o nā ʻokoʻa ʻē aʻe, pehea e lawe ʻia ana kona maʻi a me ka nānā ʻana - ma ka kikoʻī o kēia kumuhana.

He aha kēia

ʻO ka papa Lada ka ʻano maʻi maʻi i ʻike ʻia e nā mea hoʻokūkū Austrian i ka hopena o ke kenekulia 20. ʻIke lākou i nā mea maʻi me nā antibodies a me ka hoʻohaʻahaʻa haʻahaʻa o ka C-peptide (ke koena protein) aia wale nō ma o nā ʻano lua, ʻoiai ʻo ke kiʻi kulekele hōʻike ia ia. A laila ua huli kēia ʻaʻole kēia ka pae mua, no ka mea ua koi ʻia ka hoʻomaka ʻana o ka insulin i nā manawa mua loa. Pēlā, ua ʻike ʻia kahi ʻano waena o kēia maʻi, ma hope i kapa ʻia ʻo Lada diabetes (latent autoimmune diabetes i nā pākeke).

Nā hiʻohiʻona

ʻO ka maʻi maʻi latent kahi palapala latent kahi e pau ai nā huaʻa pancreatic beta. He nui nā mea noiʻi e kapa i kēia ʻano maʻi "1.5", no ka mea like he like me ke ʻano lua ma ka papa lohi, a ʻo ka mea mua i nā mīkini. ʻAʻole paʻakikī ke hana i kahi maʻi kūpono me ka noiʻi hou ʻole. Inā hana ʻole kēia a mālama ʻia ka maʻi like me ka maʻi maʻamau ʻo ka maʻi 2 (ka lawe ʻana i nā papa kala-hoʻohiolo ʻana), a laila hana nā pancreas i ka palena, a ʻo ka make ʻana o nā cell beta e hoʻokau wale ʻia. Ma hope o kahi manawa pōkole - mai ʻeono mau mahina a hiki i 3 mau makahiki - e pono ai i ke kanaka ke ʻano o ka insulin inikini ikaika, ʻoiai me ka papa ʻano maʻamau ʻo ka maʻi diabetes mellitus e like me ka nui ma hope.

ʻO nā maʻi me ka maʻi maʻi latent e loaʻa pinepine i ka maʻi

ʻO nā ʻokoʻa nui ma waena o ka palapala latent a me nā maʻi diabetes type 2:

• ka lawa ʻole o ke kaupaona ʻana (ʻo nā hihia o nā ʻano latent i nā mea maʻi me ka obesity e loaʻa ʻole ka paʻakikī);
• hōʻemi iki i nā pae o C-peptides i ke koko ma kahi ʻōpū ʻole a ma hope o ka lawe ʻana i ka hopena o ka glucose;
• ke komo nei i loko o ke koko o nā antibodies i nā pihi pancreatic - ka pale ʻole o ka maʻi maʻi maʻi e hoʻouka iā ia;
• hōʻike ka hōʻike kikoʻī i kekahi ʻano hoʻohālikelike i nā kinipona beta.

Nā Hoʻomaka

ʻO ka "Palapala maʻi Laʻi ʻo Lila Diabetes Health Clinical" kahi i kau ʻia e nā kauka e kau nei i kēia mau koi:

• ʻo ka hoʻomaka ʻana o ka maʻi he 25-50 mau makahiki. Inā ma kahi o kēia manawa ua loaʻa ke ʻano o kekahi maʻi me ka maʻi type 2, a laila pono ke nānā iā Lada, ʻo ka mea i waena o nā poʻe maʻi me ka lua, ʻo 2 a 15% hoʻi i loaʻa kahi ʻano mea maʻamau, a ʻo ka poʻe i loaʻa ʻole i ka obesity e loaʻa kēia maʻi ma ka hapalua o nā hihia;
• hōʻike iki o ka hoʻomaka o ka maʻi: ka nui o kēlā me kēia lā o ka urine e hoʻonui (ʻoi aku ma mua o 2 lita), kū ʻia kahi makewai ikaika, hōʻemi ka mea maʻi i ka kaumaha a manaʻo nāwaliwali. Eia nō naʻe, ʻo ka papa o ka maʻi Lada maʻi he asymptomatic;
• hui kino kikoʻī ma lalo o 25 kg / m2, ʻo ia hoʻi, ma ke ʻano he kānāwai, ʻaʻohe huelo a i ʻole ke kaumaha ma waena o ka poʻe e mālama ana;
• ka hele ʻana mai o nā maʻi autoimmune i ka wā ma mua a i kēia manawa paha;
• maʻi maʻi autoimmune i nā pili pili pono.

ʻO ka underweight kahi hōʻailona maʻamau o kahi kikoʻī o ka maʻi.

Inā hāʻawi ka mea maʻi mai ka 1 a i ka 1 mau pane i nā kuhikuhi mai kahi kikoʻī i hāʻawi ʻia, a laila hiki i ka hopena ke loaʻa i kahi ʻano autoimmune ma lalo o 1%, inā i loaʻa i ka 2 a i ʻole nā ​​pane hou aʻe, ʻoi aku ka nui o ka loaʻa ʻana o ka maʻi Lada ma kā 90%. I ka hopena hope loa, pono kahi kanaka e hoʻomaʻamaʻa hou.

Naʻi hoʻolika

Ua ʻike maopopo ʻia nā ʻano maʻi diagnostic i kēia mau lā i ka palapala latent o ka maʻi. ʻO ka mea nui, inā he manaʻo kānalua ʻoe i kēia ʻano, ʻo ia nō ka hoʻomalu ʻana i nā noiʻi hou aʻe.

No kēlā me kēia ʻano maʻi maʻi, he koʻikoʻi ka maʻi maʻi.

Ma hope o nā hoʻokolohua maʻamau no ka meli a me ka hemoglob glycated, hāʻawi ka mea maʻi i ke koko no nā hōʻike ʻana ma lalo nei:

Mellitus non-insulin-hilinaʻi mellitus

• ka hopena o ka pae o ka autoantibodies e glutamate decarboxylase GAD. ʻO kahi hopena maikaʻi, ʻoiai inā he kiʻekiʻe ka nui o ka antibody, ma ka hapanui loa e hōʻike ana i ka loaʻa ʻana o ka maʻi maʻi ma kahi kanaka;
• wehewehe a me ka loiloi o ICA - autoantibodies i loko o nā aʻai o ka pancreas. ʻO kēia noiʻi pū kekahi i ka mea mua e wānana i ka holomua o ka maʻi latent ʻole. Inā aia ka anti-GAD a me ICA i ke koko, hōʻike kēia i kahi ʻano nui loa o ka maʻi autoimmune;
• ka hoʻoholo ʻana o ka pae o C-peptide, kahi mea e ka hua o ka biosynthesis o ka nui o ka insulin. ʻO ke kumukūʻai i hoʻohālikelike i ka pae o ka insulin ponoʻī. Inā hōʻike ka loiloi i ka anti-GAD a me C-peptides haʻahaʻa, ʻikeia ka mea maʻi i ka maʻi Lada maʻi. Inā he anti-GAD ke hele mai akā he maʻamau ka pae o C-peptide, nā ʻōkuhi ʻē aʻe e kuhikuhi ʻia;
• ke hōʻike ʻana o nā holomua kiʻekiʻe HLA, nā māka hōʻailona genet o ka maʻi type 1 (ua pili ʻole kēia pilina me nā maʻi type 2). Eia kekahi, nānā nā mākaʻikaʻi DQA1 a me B1;
• ka ʻike ʻana i nā antibodies i nā lāʻau lapaʻau e pili ana i ka insulin.

Hoʻomaʻamaʻa

Me ke ala kuhi hewa, e lilo koke ka maʻi Lada i ka maʻi nui, a pono ke ahonui e hoʻokele i nā dosis nui o ka insulin. E pōʻino ʻole kekahi kanaka, e loaʻa nā hewa. Inā ʻaʻole ʻoe e hoʻololi i ka papa o ka mālama ʻana, pono kēia ke aloha i ka maʻi a i ʻole ka make.

ʻO ka inikua Insulin kahi e pono ai ʻoe e hoʻomaka

Hoʻomaka ka hoʻokūkū kūnaehana o ke kime autoimmune i ka hoʻomaka ʻana o nā dosis liʻiliʻi o ka insulin.

Pono e pono i ka inika insulin no:

• ka mālama ʻana i ke koena pancreatic huna. ʻO ka emi ʻana o ka hana o ka beta-cell he mea pono e mālama i ka pae kiʻekiʻe o ka glucose koko, e hoʻemi i ka hōʻemi o ka hypoglycemia a pale i ka hoʻomohala ʻana o nā pilikia o ka maʻi;
• ka hemo ʻana o ka maʻi autoimmune o ka pancreas ma ke kaemi ʻana i ka helu o nā autoantigens kahi a ke ʻano nui o ka ʻōnaehana pale a hoʻomaka i ke kaʻina hana o ka hoʻoulu ʻana. Ua hōʻike ʻia nā hoʻokolohua Laboratory ʻo ka hoʻomaka ʻana o nā dosis liʻiliʻi o ka insulin i ka wā lōʻihi ke alakaʻi i ka hōʻemi o ka nui o nā autoantigens i loko o ke koko;
• ka mālama ʻana i kahi pae glucose maoli e pale i nā pilikia koke a me nā lehulehu.

Hoʻokumu ʻia nā hana maʻi immunological no ka mālamaʻana i kekahi mau maʻi autoimmune. ʻAʻole liuliu, ua wānana nā kānakaʻepekema i ka puka ʻana o ia mau ʻano no ka mālama ʻana i ka maʻi autoimmune o ka pancreas.

ʻO ka olakino olakino a me ka hoʻōla ʻana he wahi nui ia o ka ʻōlelo

ʻO ka mālama ʻia ʻana o ka maʻi Lada maʻi, ma kahi o ka ʻohi ʻana i ka insulin, ua komo pū nō hoʻi:

• ka lawe ʻana i nā lāʻau lapaʻau e hoʻonui ai i ka paepae o ka nānā ʻana o nā ʻiʻo peripheral i insulin;
• kahi pāpā i ka lawe ʻana i ka mea hoʻoulu i ka hana insulin (me ka piha o ka pancreas a me ka hoʻonui ʻana o ka hana i ka insulin);
• ka paʻa mau o ke kō koko;
• ka neʻe ʻana i kahi pāʻai haʻahaʻa-ʻokoʻa (aʻo ka mea maʻi hiki ke ʻai i kahi kīkē liʻiliʻi liʻiliʻi);
• ka hoʻoikaika kino kino (koe wale nō me nā hihia me ka nui o ke kaumaha o ke kino);
• hirudotherapy (hana lapaʻau e hoʻohana ana i nā leema lapaʻau kūikawā).

Mai hōʻino ma mua o ka moʻolelo.

Ma hope o ka hoʻonohonoho ʻana me ke kauka hele ʻana, hiki nō hoʻi ia ke hoʻohana i ka lāʻau lapaʻau kuʻuna. Ma ke kānāwai, ʻo ka launa no ka mālama ʻana i ka decoctions a me tinctures o nā lāʻau lapaʻau, e hoʻemi kuʻikuʻi i ka pae o ka glucose i loko o ke koko.

ʻO ka maʻi Lada e like me nā ʻano ʻē aʻe, me ka pohō ʻole ʻana a me ka mālama kūpono hiki ke alakaʻi i nā hoʻopiʻi he nui. No laila, i ka hōʻike o ka maʻi diabetes, he mea nui ia e hana i nā noi i ʻole e haʻalele i ka hopena o ka lāʻau lapaʻau kūpono, a hiki i ka hopena ke hiki i ka maʻi a me ka make.