ʻO nā maʻi o ka ʻōnaehana cardiovascular aia kekahi o nā kumu maʻamau o ka make i loko o Lūkia a me ka honua. Ma lalo o kēia mau kūlana, he mea nui ka pale ʻana o ka maʻi naʻau. Hāʻawi ke lāʻau lapaʻau i kahi koho ākea o nā lāʻau lapaʻau e ʻae ana i ka hoʻopau ʻana i nā maʻi i kēia wahi. ʻO kekahi o ka lāʻau lapaʻau Liprimar.
ATX
ʻO ka code ATX o ka lāʻau lapaʻau ka C10AA05. ʻO ka mea e ola ai ka atorvastatin (ka pūʻulu o nā statins).
ʻO Liprimar, kahi lāʻau lapaʻau e hoʻopau ana i nā maʻi o ka ʻōnaehana cardiovascular a lawelawe e pale iā lākou.
E hoʻokuʻu i nā palapala a me ka ʻano
ʻO ka hoʻonohonohoʻana o nā papa ka waiwai ikaika a me nā mea kōkua.
ʻO Atorvastatin, ka mea i hōʻike ʻia e ka paʻakai kalaiwa, he hana ma ke ʻano he mea ikaika. ʻO kona kumukūʻai i kēlā me kēia papa pākēpē e hilinaʻi i ka nui o ka lāʻau (mai ka 10 mg a 80 mg).
ʻO ka ʻōmole hoʻohui mea multicomponent. Aia i ka:
- lactose monohala;
- kaleka ka calcium;
- sosa ʻo ke pākeke laupili;
- MCC;
- hydroxypropyl cellulose;
- hīmeni 80;
- magnesium stearate;
- ʻO keʻokeʻo Opadra.
ʻO ka lāʻau i hōʻike ʻia i ka puka papa, akā naʻe, hiki iā ia ke loaʻa he mau dosage. Ke keʻokeʻo a he elliptical nā papa papaʻi, i uhi ʻia me ka pale keʻokeʻo ma luna. No kahi keʻena kūpono, hiki iā ʻoe ke koho i nā papa me kahi kaʻauao o nā mea ikaika 10, 20, 40 a i ʻole 80 mg.
No kahi hoʻokō kūpono maʻalahi, hiki iā ʻoe ke koho i nā papa Liprimar me kahi hapa o 10, 20, 40 a i ʻole 80 mg o ka mea ikaika.
Ke kuhi nei i nā lāʻau lapaʻau - blisters kahi 7 a 10 mau papa i hoʻopili ʻia. Aia ka mea i hoʻopili ʻia ai kahi kāleka 2, 5, 8 a i ʻole 10 mau poloka.
Ka hana lāʻau lapaʻau
Ke loaʻa nei ka lāʻau i nā waiwai hypocholesterolemic a me ka lipid-hoʻemi haʻahaʻa.
ʻO ka papa hana koʻikoʻi o nā papa he atorvastatin, ka mea i manaʻo ʻia ʻo kahi mea i hoʻowalewale pili ʻia o ka HMG-CoA reductase. Hoʻopili kēia waihona i ka hoʻoponopono o ka hoʻololi o HMG-CoA i mevalonate. Hoʻonui ka papa i ka nui o nā receptors LDL.
Ma lalo o ka hopena o ka atorvastatin, hiki i nā loli e hiki mai ana i ke kino:
- i loko o ke koko, ua hōʻemi ʻia ka nui o nā lipoproteins haʻahaʻa haʻahaʻa;
- hoʻonui ka ʻike o nā lipoproteins density kiʻekiʻe;
- ka emi o ka ʻike o triglycerides a me apolipoprotein B.
Lapaʻau lāʻau
Ma hope o ka lawelawe waha, ua komo koke ʻia ka nui o nā mea ikaika. Loaʻa ka ʻike kiʻekiʻe loa i ke koko ma hope o nā hola 1,5-2 ma hope o ke komo ʻana o ka lāʻau lapaʻau. Ka kiʻekiʻe ka bioavailability o ka waiwai - e pili ana i ka 95-98%.
Ma lalo o ka hana a ka huaʻina ikaika ʻo Liprimar, ʻoi ka ʻike ʻana o ka lipoproteins density kiʻekiʻe ma ke koko.
Aia hoʻi i ke kōpae koko i ke kiʻekiʻe (e pili ana i ka 98%).
Hoʻopili ʻia ʻo Atorvastatin a me kāna mau metabolites ma o ka ate. ʻO ka palena manawa he 28 mau hola.
Nā hōʻailona no ka hoʻohana ʻana
Nui nā kumu kumu e kuhikuhi ai i kahi kauka i kēia lāʻau lapaʻau.
ʻO nā maʻi me ka hypercholesterolemia:
- Hoʻopiha i nā meaʻai. Kōkua ka lāʻau lapaʻau e hoʻokō i ka hopena makemake i ka hihia o ka mālama ʻana i ka meaʻai. E loaʻa paha i kēia mau ʻōhua ka i kēia: hypercholesterolemia mua, heterozygous a i ʻole i ʻano like ʻole o nā maʻi. I kēia hihia, kahi hōʻemi i ka LDL-C, kolamu, a me ka triglycerides i loaʻa.
- ʻO ka hoʻonuiʻana i ka mālama lipid-hoʻohaʻahaʻa i ʻole i hiki ʻole ke hoʻohana i nā ʻano o nā lāʻau ʻē. Maikaʻi kēia koho i ka famchial homozygous hypercholesterolemia.
No ka pale ʻana i nā maʻi o ka ʻōnaehana cardiovascular i kuhikuhi ʻia:
- ʻO ka poʻe maʻi i ka pilikia no ka hoʻomohala ʻana i nā pathologies cardiovascular kumu mua.
- Ke pale nei i ka hōʻeha ʻana o ka naʻau, nā kīkē a myocardial a me ka hoʻomohala ʻana i nā kūlana ʻoi me ka angina pectoris. I kēia hihia, ua kuhikuhi ʻia ka lāʻau lapaʻau no nā mea maʻi me ka maʻi naʻau coronary a me nā maʻi naʻau ʻē aʻe.
Nā Hoʻohui
He nui nā contraindications i ka lāʻau lapaʻau. E pili ana kēia:
- ke ahonui i kēlā me kēia mau mea mai ke ʻano o nā papa;
- ʻo ka hāpai a me ka manawa o ka umauma (inā i kuhikuhi ʻia kēia lāʻau lapaʻau, ʻānō ʻia ka hoʻoulu ʻia ʻana o ka ʻaihue.
- lactose intolerance, lactase deficiency (congenital);
- glucose-galactose malabsorption;
- nui nā maʻi poli, me ka hana nui o ka transaminases hepatic;
- kamaliʻi i lalo o 18 mau makahiki o ka nui (ʻo ka ʻokoʻa ke hōʻike ʻana i ka hypercholesterolemia heterozygous ʻohana, i ka manawa i kauoha ʻia ai ka lāʻau lapaʻau no nā keiki mai 10 mau makahiki).
ʻAʻole i kuhikuhi ʻia ka liprimar no nā maʻi naʻau palau.
Pehea e lawe ai i Liprimar
Kuhi ʻia nā papa no ka hoʻokele waha. I kēia hihia, pono e holoi nui ʻia i ka lāʻau me ka wai. ʻAʻole make ka ʻai i ka wikiwiki a me ka hoʻopiha piha ʻana i ka mea hana, no laila e hiki ke ʻai ʻia nā papa i kēlā me kēia manawa o ka lā ma mua o a ma hope o ka pāʻina.
Pono Atorvastanin e hoʻohālikelike i nā hihia kahi i loaʻa ʻole ai kahi meaʻai kūikawā, ka hoʻomaʻamaʻa a me nā ʻano lāʻau ʻē aʻe i lawe ʻia i ka hopena makemake.
Lawe ʻia nā papa he 1 manawa i kēlā me kēia lā, ʻoiai ke ʻano ka nui o ke ʻano mai 10 mg a 80 mg. ʻO ka nui o ka lā helu i kēlā me kēia lā he 80 mg o ka atorvastatin. No kēlā me kēia mea maʻi, ua koho pono ʻia ka pākēneka kiʻekiʻe e like me ka maʻi a me nā ʻano lāʻau ʻē aʻe.
I kekahi mau hihia, ua hoʻolaha ʻia ka lāʻau atorvastatin me ka hoʻonui iki i ka dosis i kēlā me kēia lā. Eia hou, loaʻa i kēlā me ke kūleʻa o ke kūleʻa ka nānā mākaukau i ke ʻano o ka mea maʻi (ka hoʻopili koko, ka naʻau a me ka hana o ke keiki).
Me ka maʻi diabetes
Wahi a nā hopena noiʻi, ʻo HMG-CoA reductase inhibitors ma kekahi mau mea e hoʻonui ai i ka kaohi ʻana o ka glucose i ka plasma koko. ʻO ka poʻe maʻi i ka hopena o ka hoʻomohala ʻana i ka maʻi hānai e ulu i ka hyperglycemia.
Ma ka manawa like, ʻike nā kauka i ka liʻiliʻi o ka nui o nā hihia, a ʻo nā pono o nā lāʻau Liprimar eʻoi aku ka nui o nā pōpilikia. No laila, ʻo nā mea maʻi me ka maʻi ʻaʻai a me ka hopena hiki pono ke lawe i ka lāʻau lapaʻau ma lalo o ka mālama ʻana o kahi kauka. Pono lākou i ka hoʻoponopono hoʻoponopono ʻia a me nā hoʻoliʻi koko.
ʻO nā maʻi maʻi me ka maʻi maʻi e lawe iā Liprimar ma lalo o ka mākaʻi o kahi kauka. Hoʻoholo lākou i ka hoʻoponopono dosage a me nā hoʻāʻo koko maʻamau.
Hiki paha ke hoʻokaʻawale i ka hapalua
ʻAʻole ʻōlelo ʻia ka papa papa e hoʻokaʻawale ʻia i ka hapalua. Hiki i kēia ke wehewehe i ka hiki ʻana o kahi pūpū, ka mea e pale ai i ka luku mua ʻole o ka waiwai ikaika.
ʻO kahi hiʻohiʻona nui ʻo ka loaʻa ʻana o nā papa me nā ʻano like ʻole. Hoʻomaʻamaʻa kēia i ka koho kūpono e ʻole ka pono no ka hoʻokaʻawale.
Nā hopena hopena
ʻO nā hopena ʻaoʻao mai ka hana e hiki ke hoʻopilikia i nā ʻōnaehana like ʻole. Hōʻike iki kahi hōʻailona liʻiliʻi loa i nā lā mua o ka mālama ʻana. ʻAʻole lākou he manawa maʻamau no ka haʻalele ʻana i ka lāʻau. Me nā hōʻailona koʻikoʻi, ua kāpae ʻia ka lāʻau lapaʻau a, inā hiki, e hoʻololi ʻia e kekahi.
- Mai ka ʻaoʻao o ka ʻōnaehana musculoskeletal, hōʻeha pinepine ka ʻeha i nā limu, arthralgia a me myalgia, ʻeha hoʻi, ka hōʻeuʻeu o nā ʻanā, nāwaliwali o ka naʻau.
- Hiki ke kūpono nā hopena mai nā ʻili sensory. Hoʻomaʻamaʻa nā mea maʻi i ka nānā ʻana o kahi pākū i mua o nā maka, tinnitus, he male ʻole o nā ʻano ʻaila ʻono.
- ʻOi paha ka hoʻomohala ʻana o ka hyperglycemia a me ka hypoglycemia.
- Hōʻike ʻia nā hihia i hōʻike ʻia o ka hiʻohiʻona o ka impotence.
ʻŌpala Gastrointestinal
Ua hōʻike kekahi poʻe maʻi i ka dyspepsia, nausea, flatulence, a me ka constipation. ʻOi aku ka maʻi maʻamau o ka eha epigastric, belching, nā puka o ka luaʻi, a me ka pancreatitis.
Hematopoietic mau hui
Ua hōʻike ʻia kekahi mau hihia o ka thrombocytopenia.
Pūnaehana pīhoihoi waena
ʻO nā hopena ʻaoʻao maʻamau mai ka hale kikowaena kikowaena he hōʻeha a me nā pilikia hiamoe. ʻO ka ʻeha, ka hypesthesia, ka paresthesia e ʻike pinepine ʻia i nā manawa pinepine. Aia nā kuhikuhi e pili ana i ka neuropathy peripheral a me ka hoʻomanaʻo ʻana i ka hoʻomanaʻo.
Mai ka pūnaehana urinary
Loaʻa paha ka hoʻomohala ʻana o ka hana papau, ka edema periferal.
Mai ka papa huhū
Leka a me nā kani waiho ʻia. Ua hōʻike ʻia kekahi mau hihia o ka maʻi ʻula interstitial.
Allergies
ʻO kahi hopena alerine i ka lāʻau lapaʻau kahi hōʻailona o ka hypersensitivity i hoʻokahi a keu aʻe paha o nā mea o ka mana. ʻO kēlā mau ʻano e like me ka urticaria, bullous rash, anaphylaxis, erythema multiforme exudative, aiʻole toxic epidermal necrolysis.
Nā ʻōlelo kikoʻī
I mea e pale ai i nā hoʻopiʻi, pono e hoʻomaopopo pono ka lāʻau lapaʻau no nā maʻi o nā palaleka o nā aʻalā a me nā puʻuwai. I nā poʻe maʻiʻelemakule, i ka loaʻa ʻana o nā pōʻino, ʻaʻole pono ka hoʻoponopono ʻana o ka dosis.
Hoʻolaha ka waipuna
Hoʻohui ʻole ʻia ka hoʻohana pū ʻana o ka lāʻau a me nā waiʻona. Hoʻohui ʻia, nā poʻe e hōʻino maikaʻi ʻana i ka waiʻona e contraindicated ma ka lawe ʻana i ka atorvastatin. Hōʻike ʻia kēia ma ka hoʻonui ʻia o nā transaminases hepatic. I nā hihia koʻikoʻi, aia kahi hopena o ka make.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
ʻAʻole pili kēia lāʻau lapaʻau i ka hopena o ka hopena. I kēia hihia, hiki i nā hopena ʻaoʻao e like me ka dizziness, tinnitus a me ka acuity ʻike ma ke ʻano o ka mālama ʻana. No kēia kumu, ke noi nei nā kauka e holo maikaʻi ʻoe.
Hoʻohana i ka wā hāpai a me ka lactation
ʻAʻole kuhikuhi ʻia nā wahine i nā lāʻau lapaʻau i ka wā hāpai a me ka umauma.
Koho ʻana ʻo Liprimar i nā keiki
Contraindicated ka lāʻau a hiki i ka makahiki 18, ʻoiai ʻaʻole i lawa nā data i ka hoʻohana ʻana i ka lāʻau lapaʻau i ka mālama ʻana i nā keiki. ʻO kahi mea ʻē aʻe i hōʻike ʻia e nā maʻi me ka heterozygous hypercholesterolemia familial. I ia mau hihia, hiki ke hana ʻia ka lāʻau lapaʻau e mālama i nā keiki mai 10 mau makahiki. Hoʻonohonoho ka lāʻau ma lalo o ka kiaʻi koʻikoʻi o kahi kauka.
Ke keu
ʻO ka dosage i kēlā me kēia lā nui ʻo 80 mg o atorvastatin. I ka hihia o ka mea e ʻoi aku i ka nui i ʻōlelo ʻia aʻe, kahi hōʻiliʻili o nā hopena ʻaoʻao ka hopena. ʻAʻohe mea lapaʻau kūikawā i kēia hihia, no laila ua kauoha ʻia ke ʻano maʻi. Ua kuhikuhi ʻia nā mea maʻi i ka hoʻomohala ʻana o ka hana KFK a me nā hoʻokolohua hoʻomaʻamaʻa hana. ʻAʻole kū maikaʻi ka Hemodialysis ma muli o ka paʻa mau o nā lāʻau lapaʻau i nā protein koko.
Hoʻopili pū me nā lāʻau ʻē aʻe
Hoʻohana pinepine ʻia ka lāʻau lapaʻau ma ke ʻano o ka hoʻomaʻamaʻa paʻakikī, no laila ʻo ka hoʻopili ʻana i ka lāʻau lapaʻau he mea nui ia.
ʻAʻole kuhikuhi ʻia ka hui
Hiki ke piʻi aʻe ka pilikia o ka myopathy me ka hoʻohana pinepine ʻana me nā fibrates, cyclosporine, acid acid nikotinic, ezetrol, lāʻau antifungal a me clarithromycin.
Me ka mālama pono
Hiki i kahi hui hui me diltiazem, erythromycin, kahi isoenzyme o ka cytochrome CYP3A4, clarithromycin hiki ke hoʻonui i ka ʻai o ka lāʻau i loko o ke koko koko.
Hiki i ka Atorvastatin ke hōʻemi i ka hoʻoneʻe ʻana o nā lāʻau lapaʻau e like me colestipol, alumini hydroxide a me ka magnesium hydroxide.
Hoʻonui ʻo Atorvastatin i ke kao o ke koko o kēia mau lāʻau āpau: ethinyl estadiol, digoxin, norethisterone.
I kēia mau āpau a pau, pono ke hoʻoponopono ʻia dosage.
Mea hana
Hana ʻia kēia lāʻau lapaʻau e Pfizer Pharmaceuticals ElElSi.
Nā kuʻina o Liprimar
Hiki i kēia mau lāʻau ke hōʻili i ka papa inoa o nā mea hoʻohālike manuahi o ka lāʻau lapaʻau:
- Ator;
- Atoris;
- Anvistat;
- The visor;
- Atomax;
- Novostat;
- Hoʻokahi
- Kauka;
- Lipona
- Lipronorm;
- Tulip;
- ʻOkaʻohana
- Torvacard
- Lipoford.
ʻO Tulip kahi hoʻohālikelike o Liprimar.
Waihue huaʻōlelo waiho nā huaʻōlelo
Mākaukau ʻia ka hoʻomākaukau ʻana o kēia hui lāʻau i nā lāʻau lapaʻau ma o ka lāʻau lapaʻau.
Hiki iaʻu ke kūʻai me ke kī ʻole
ʻAʻole hiki iā ʻoe ke kūʻai i nā lāʻau lapaʻau me ke ʻole o ka papa inoa.
Kūʻai
Hoʻololi nā kumukūʻai ma muli o ke ʻano a me ka helu o nā papa:
- 10 mg mau papa (100 pcs.) - e pili ana i ka 1600 rubles;
- 20 mg papa (100 pcs.) - kahi o 2500 rubles .;
- 40 mg papa (30 pcs.) - kahi he 1100 rubles .;
- 80 mg papa (30 pcs.) - kahi he 1200 rubles.
Mākaukau ʻia ka hoʻomākaukau ʻana o kēia hui lāʻau i nā lāʻau lapaʻau ma o ka lāʻau lapaʻau.
Ke waiho nei i nā kūlana o Liprimar
E mālama i nā papa i kahi wahi hiki ʻole i nā keiki i ke mahana o + 15 ... + 25 ° C.
ʻO ka lā kau
Ka lōʻihi o ka mālama - 3 mau makahiki.
Nā Hōʻikeʻike Liprimar
Eugene, cardiologist, he mau makahiki lapaʻau i nā makahiki 11, ʻo Moscow
Hoʻoma pinepine pinepine wau i kēia lāʻau lapaʻau i nā mea maʻi me ka maʻi naʻau coronary a e hōʻemi i ka hopena o nā maʻi cardiovascular. Ua hoʻomau ʻia kēia lāʻau lapaʻau i nā loiloi he nui i hōʻike ʻia e hōʻike ʻia, aia nō kahi hōʻike pono. ʻO kekahi o nā pono ponoʻae o ka hoʻohana ʻana ia i kona maʻa mau maikaʻi, nā ʻāpana ʻaoʻao ke nānā ʻole. ʻO ka hemahema ʻo ke kumukūʻai kiʻekiʻe o ka mālama ʻana me ka hoʻohana wā lōʻihi.
Lydia, 56 makahiki, Yaroslavl
Ua pā ʻo ia i ka puʻuwai puʻuwai, a ma hope ua kuhikuhi ke kauka i nā lāʻau kūikawā e pale ai i ka neʻe hou ʻana. Nani nā papa papaʻaina. Lawe au i 1 papa i hoʻokahi manawa i ka lā, e like me ke kauka ʻana. ʻAʻole hiki iaʻu ke hoʻokolokolo pono, akā, ʻaʻohe hopena hopena.
Vitaliy, 42 makahiki, Pskov
Ua hōʻike ʻia au me ka cholesterol kiʻekiʻe. Hoʻomau wau ma ka papaʻai no ka manawa lōʻihi, akā ʻaʻole hiki iaʻu ke hoʻemi i nā hōʻailona. Ma hope o ka haki ʻana, hoʻohālikelike ʻia kēia mau lāʻau. Ua hoʻomaka wau e hana. He maʻalahi ka lāʻau lapaʻau, ʻoiai pono ʻoe e inu i hoʻokahi manawa i ka lā. I ke kakahiaka hele aku au i ka pūlima a hele i ka hana. Ka hoʻāʻo hou ʻana, ua hoʻēmi iki ka cholesterol.
