ʻO Carbamazepine kahi lāʻau lapaʻau i loaʻa i ka hopena psychotropic a me ka antiepileptic hopena. ʻOi loa ka maikaʻi o kēia hāmeʻa, akā he nui nā hopena, no laila e hoʻohana kūʻokoʻa wale ʻia e like me ke kauka ʻana i ke kauka, ʻaʻole iʻoi aku i nā nui o nā kauka i hōʻike ʻia i nā ʻōlelo aʻoaʻo no ka hoʻohana.
Tagu inoa
ʻO kēia mau papa ma ka Latin, i hoʻohana ʻia e nā lāʻau lapaʻau, kapa ʻia ʻo Carbamazepine.
ATX
I loko o ka hoʻonohonoho hoʻonohonoho hoʻonohonoho anatomical-therapeutic-chemical classization no nā lāʻau lapaʻau, loaʻa iā ia kahi code - N03AF01.
ʻO ka Carbamazepine kahi lāʻau lapaʻau me ka hopena psychotropic a antiepileptic.
E hoʻokuʻu i nā palapala a me ka ʻano
ʻO ka mea nui e hoʻopili pono ai i ka carbamazepine ʻo ia ka waihona o ka inoa like. Ua loaʻa i nā mea kōkua:
- kōpana;
- talc;
- magnesium stearate;
- polysorbate;
- povidol.
Loaʻa kēia lāʻau lapaʻau i ke ʻano o nā papa. Ke hōʻike ʻia nei ka lāʻau lapaʻau me kahi pākuʻi o 200 mg i loko o kahi pā kuhi blister. Hiki i kahi pūʻulu mai kahi 1 a i 5 mau paʻi.
I loko o nā hale hoʻomaha, ua hāʻawi ʻia ka lāʻau lapaʻau i nā waihona i hoʻolālāʻia no 500, 600, 1000, 1200 pcs. Hoʻopaʻa ʻia kēlā me kēia pahu i kahi pahu pahu kūʻokoʻa.
Pehea ia e hana?
He lāʻau lapaʻau kēia i hōʻike ai i ka hopena neurotropic, antidiuretic, antiepileptic, anticonvulsant, normotimic, antipsychotic, psychotropic effects.
Loaʻa ka hopena antiepileptic o ka lāʻau ma ka hoʻomau ʻana i nā membrane intercellular o nā neurons i hoʻopili ʻia i ka overexcitation. Mālama ka mea hana i nā hoʻopiʻi serial a hoʻēmi i ka wikiwiki o ka hoʻouna ʻana i nā pulses. E kōkua ka lāʻau lapaʻau e hōʻemi i ka glutamate, kahi mea ne neurotransmitter.
Ke hopena lāʻau lapaama ʻoamaamaama a hiki i ka hopena o ka neurotropic a me ka normotimic hopena, e hiki ai ke hōʻemi i ka pinepine o ka lawe i ka epilepsy.
ʻO ka lāʻau lapaʻau ka hōʻemi o ka hopena metabolic o norepinephrine a me ka dopamine. ʻO ka hoʻohanaʻana i kēia lāʻau lapaʻau e ka poʻe me ka epilepsy hiki ke hōʻemi i ka nui o ka hoʻokuʻi a me ka pae o ke kaumaha, hoʻokaʻawale i nā hopohopo nui, etc.
Eia kekahi, e kōkua ke lāʻau lapaʻau e hoʻopau i ka hōʻeha paroxysmal me ka neuralgia koʻikoʻi.
ʻO ka hopena o ka lāʻau lapaʻau ma ka mālama ʻana i ke kinikini haʻalele i hoʻokuʻu ʻia ke kolohe e hoʻoneʻe i ka hana hoʻomāhuʻi a me nā hōʻike ʻē aʻe.
I ka poʻe me ka maʻi maʻi maʻi insipidus, hiki i kēia lāʻau lapaʻau ke hōʻemi i ka diuresis.
Lapaʻau lāʻau
ʻO ka lohi ʻana o ka lāʻau ka lohi. ʻO ka kukuna plasma kiʻekiʻe loa ma hope o 12 mau hola. Me ka hoʻohana maʻamau, ua hōʻea nā mea kāhiko ma hope o 7-14 lā.
ʻO ka metabolism ka hopena e kūpono i ka palū ma muli o ka hopena o ka microsomal enzyme epoxide hydrase.
I nā poʻe maʻi i hoʻohana i kēia lāʻau lapaʻau hoʻokahi, ua pau ia i loko o kahi awelika o 36 mau hola.
Inā hoʻohana ʻia ka lāʻau lapaʻau ma ke ʻano he lāʻau multicomponent e hoʻohana ana i nā lāʻau antiepileptic ʻē aʻe, hiki ke hōʻemi ʻia kona manawa hoʻopau ʻia i nā hola 9-10. Hoʻopauʻia nā metabolite inactive i kahi nui aʻe me ka urine a i kahi haʻahaʻa iki me nā feces. I nā keiki, ʻoi aku ka wikiwiki o kēia lāʻau lapaʻau.
He aha ka mea e kōkua ai?
Hōʻike ʻia ka loaʻa ʻana o nā kaʻina pili:
- epilepsy
- papaleʻa glossopharyngeal;
- hali palapala hoʻoweliweli;
- polydipsia a me polyuria ma ka diabetes insipidus;
- ʻeha ka maʻi ʻeha me ka maʻi neuropathy maʻi.
- maʻi bipolar afili;
- hana hōʻino o ka neʻe a me ka nerve trigeminal;
- ka hopena trigeminal i hoʻopilikia ʻia i ke kua o ka lehulehu sclerosis, etc.
ʻO ka hiki i ka hoʻohana ʻana i kēia lāʻau lapaʻau no kekahi mau kūlana patolo e loaʻa ana i nā maʻi maʻi e hoʻoholo ʻia e ke kauka.
Nā Hoʻohui
Nui a he mau kūlana i pāpā ʻole ʻia ai ka hoʻohana ʻana o kēia pono hana. ʻO kēlā mau pilikia a me nā ʻano e loaʻa:
- poloka antrioventricular;
- Pākuʻi molmole penmyrent
- manuahi maʻi pehu;
- puʻuwai a me nā pilikia hapa;
- ka helu ʻai koko keʻokeʻo a me ka helu platelet;
- ka heleʻana o hypersensitivity.
Me ke akahele, pono ʻoe e lawe i kēia lāʻau lapaʻau inā ke loaʻa mua i ka mea maʻi i nā hōʻailona o ka myelodepression.
Pehea e lawe ai
I ka epilepsy, hoʻohana mua ʻia ka lāʻau i loko o ke ʻano o ka monotherapy. Hoʻomaka ka mālamaʻana i nā hōʻemi liʻiliʻi ma waena o 100 a 200 mg / lā.
Me ka neuralgia o ka glossopharyngeal a me ka nerve trigeminal, hoʻohana kēia lāʻau lapaʻau i ka waihona ʻana o 200 mg. Kūwīwī, piʻi ka hāmeʻe i ka 600-800 mg. Hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau lapaʻau a hiki ke hoʻopau ʻia ʻana o ka maʻi ʻeha.
Me ka neuralgia o ka ternary nerve, hoʻomaka ka lāʻau kālamazepine e lawe i loko o kahi waihona o 200 mg.
Me ka polydipsia a me polyuria, i hoʻolālā ʻia me ka diabetes insipidus, ua kuhikuhi ʻia ka lāʻau lapaʻau ma kahi o ka 200 mg 2-3 mau manawa i ka lā.
I ka mālamaʻana i nā hōʻailona hōʻemi e pili ana i ke kua o ka waiʻona, ʻo ka hoʻomaka ʻana mai ka 200 mg 3 mau manawa i ka lā.
Ma keʻano he mea kākoʻo i ka hopena o nā maʻi bipolar kūlohelohe, ua kauoha ʻia ka lāʻau lapaʻau no nā pākeke i kahi kaila o 400 ka 1600 mg. Ua māhele ʻia kēia maʻi i ka 2 a i ʻole nā 3 kauā.
I ka hihia o ka ʻeha, pono e hoʻāla ʻia ka lāʻau lapaʻau me kahi maʻi o 100 mg 2 mau manawa i kahi lā. I ka wā e hiki mai ana, hoʻonui ka nui o ka lā i ka 200 mg.
Ma mua o hoʻokahi a ma hope o kahi pāʻina
Hoʻomaopopo nā poʻe loea he nui i kuhi ʻia ʻole e lawe i kēia lāʻau lapaʻau i ka ʻōpū ʻole, no ka mea ke hoʻonui nei kēia i ka hopena o nā hopena ʻaoʻao mai ka digestive tract. Lawe i ka lāʻau lapaʻau pono i ka wā a i ʻole maʻa o ka ʻaina. Pono ka holoi ʻana i ka lāʻau me ka wai.
ʻAʻole ʻōlelo ʻo Carbamazepine no ka hoʻohana ʻana ma ka ʻōpū ʻole.
Pehea ka lōʻihi e inu ai?
ʻO ka lōʻihi o ka lāʻau e pili ana i ka maʻi maʻi, ka mea maʻi, ka hopena a me nā hopena kū hoʻokahi. No kekahi mau pathologies, kahi papa 1-2 wiki a mālama pono ʻia ka lawa. Eia nō naʻe, hiki ke kuhikuhi ʻia i kahi lā ola ola.
Lawe i ka lāʻau lapaʻau no ka maʻi maʻi maʻi
Pono ka poʻe me ka maʻi maʻi e lapaʻau i ka lāʻau me ka makaʻala.
Ma ka polyneuropathy diabetes, ʻo ka nui o ka lāʻau e 200 mg 2 mau manawa i ka lā.
Nā hopena hopena
He lāʻau lapaʻau maikaʻi loa kēia lāʻau lapaʻau, hiki ke hoʻohana ʻia i ka mālama ʻana i nā mamao o nā maʻi āpau.
ʻO nā hopena maikaʻi loa, ka hopena pinepine ka hiki ʻole i ke kanaka ke alakaʻi i kahi ʻano hana piha, hiki ke lilo i mea paʻa i ka lāʻau maʻi.
ʻŌpala Gastrointestinal
ʻO nā hopena ʻaoʻao o ka carbamazepine mai ke kumu gastrointestinal i loaʻa:
- ninini
- utuka
- ka malo maloʻo
- jaundice
- nā maʻi ʻino;
- lilo o ka momona;
- hepatitis;
- lōkohu
- huakai.
ʻO ka hoʻonui nuiʻana o ka makemakeʻai kekahi o nā hopena o ka lawe ʻana i ka lāʻau Carbamazepine.
Eia kekahi, ʻo ka hoʻohana ʻana i ka lāʻau hiki ke loaʻa i ka nānā o ka stomatitis a me nā ala ʻē aʻe o ka waha waha. ʻO ka hoʻohanaʻana i ka carbamazepine hiki ke alakaʻi i ka hoʻopau ʻole o ka ate.
Hematopoietic mau hui
I ka manawa pinepine, ma hope o ka lōʻihi o ka lawe ʻana i kēia lāʻau lapaʻau, ulu aplastic a me hemolytic anemia. Eia kekahi, ʻo ka hiʻohiʻona o nā palia e like me:
- ooliaopiaopenia;
- leukocytosis;
- eosinophilia;
- erythrocyte aplasia;
- reticulocytosis.
Me ka hoʻohana lōʻihi ʻana o ka lāʻau carbamazepine, ulu nā anemia.
I waena o nā mea ʻē aʻe, e kū'ē ana i ke kuana o ka lawe ʻana i ka lāʻau lapaʻau, hiki paha i ka lymphadenopathy.
Pūnaehana pīhoihoi waena
Mai ka ʻaoʻao o ka pūnaehana neoneo i ka wā e lawe ai i ka carbamazepine, hiki i kēia mau ʻano ʻaelike ʻole:
- makehewa;
- poʻomanaʻo
- lohe ʻole ka hoʻolohe;
- nystagmus;
- diplopia;
- ataxia
- hana ʻino;
- ʻike ʻole;
- paoho ana i ke poo;
- neuritis.
ʻO ka lethargy, kani leo ʻole i ke poʻo, dizziness attack ka hopena o ka ʻaoʻao o ka pūnaehana kūloko o ka pūnaehana.
ʻO ka hopena o ka ʻaoʻao, i hōʻike ʻia e nā mea hoʻokūkū, hoʻāla ʻia o ka psychosis, ʻehaʻeha o ka maʻi, nā dysarthria, etc., he mea maʻamau ʻole.
Mai ka pūnaehana urinary
ʻO ke kūpaʻa ʻana ma ke ʻano o ka lawe ʻana i kēia lāʻau lapaʻau, hiki i ka hala ʻole ke kau a me ke kūkulu ʻana i ke kaʻina o nā maʻi. Loaʻa pinepine nā maʻi i ka hana o ke aʻalolo.
Mai ka papa huhū
Hoʻopiʻi pinepine ʻo ia i ka lolo a me ka dyspnea.
Mai ka papa hana hanu, hiki i ka carbamazepine ke hoʻonāukiuki i ka maʻi pneumonia.
ʻŌnaehana Endocrine
He mea kupaianaha loa ia e lawe aku i kēia lāʻau lapaʻau i ka dysfunction o ka gland thyroid. Malia paha kahi hoʻomohalaʻana o ka galactorrhea a me gynecomastia.
Allergies
Hiki i nā maʻi ke hōʻeha i ka ʻāʻī ʻili. Kekahi hopena, hoʻonā ʻia nā hopena alia i loko o ke ʻano o ka arthralgia, ka maʻi, a me ka lymphadenopathy.
Nā ʻōlelo kikoʻī
Ma mua o ka kuhikuhi ʻana i ka lāʻau lapaʻau, pono ke kauka ke kauka i kahi loiloi piha loa e hoʻoholo i kekahi o nā kongana koko, pono e nānā pono ʻia ma hope o ka hoʻomaka ʻana o ka lāʻau.
Manaʻo ʻia ka lawe ʻana i ka lāʻau e pono ai no nā poʻe me ka hoʻonui ʻana i ke koʻikoʻi intraocular.
Ma ke alo o nā maʻi maʻamau o nā kino kūloko a me nā maʻi kumulapapa o ke kinipōpō ma waena, pono ia e mākaʻikaʻi mau i ke ʻano o ka mea maʻi. I ka hoʻomaʻamaʻa ʻana o nā maʻi maʻi HIV e koi mau ana ka kiaʻi ma ka helu o nā leukocytes.
Hoʻolaha ka waipuna
I ka wā mālama, pono ka mea maʻi e hōʻole i ka lawe ʻana i nā mea inu ʻawa.
I ka wā o ka hoʻokele ʻana o ka carbamazepine, pono pono e haʻalele loa i ka hoʻohana ʻana i nā mea inu ʻapo.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
Pono e mālama i nā ʻoihana e pili ana i kēia lāʻau lapaʻau i ka wā e alakaʻi ana i ke kaʻa a hana i ka hana hiki ke pilikia.
Hoʻohana i ka wā hāpai a me ka lactation
ʻO ka hānau ʻana o kahi keiki e ka mea maʻi he contraindication no ke alakaʻi ʻana i ka maʻi me kēia lāʻau lapaʻau, mai ka mea e hiki ai ke hoʻonāukiuki i nā mea hōʻino i loko o ka pēpē. ʻO ka ʻōpala hoʻi he contraindication no ka hoʻohana ʻana i ka lāʻau lapaʻau.
ʻO ke kahuli a me ka lactation, he mau contraindications no ka lawe ʻana i ka lāʻau lapaama caramazepine.
Koho ʻana iā Carbamazepine i nā Keiki
No nā keiki, kuhikuhi ʻia kēia lāʻau lapaʻau pinepine ma mua o nā pākeke. Ua ʻāpono ʻia kona hoʻohana ʻana i ka epilepsy. No nā keiki ma lalo o 5 mau makahiki aku, kahi ʻia ma ke ʻano he 20 a 60 mm. Inā he pono, hiki ke pāpālua ʻia. Ua ʻōlelo ʻia nā keiki ma mua o 5 mau makahiki - 100 mg i kēlā me kēia lā. Ua māhele ʻia kēia maʻi i ka 2-3 maʻi. Hiki i ke lāʻau lapaʻau ke kuhikuhi i nā keiki e hoʻopau i nā hōʻike o ka maʻi insipidus maʻi.
Hoʻohana i ka wā kahiko
I ka mālamaʻana i nā pākeke, hoʻohana ʻia nā dole liʻiliʻi.
I ka mālamaʻana i nā hōʻailona hōʻemi i nā poʻe ma luna o 65, ʻo ka lāʻau i hōʻike ʻia e 100 mg 2 mau manawa i ka lā.
Hoʻomaopopo ʻia ka lāʻau lapaʻau e hoʻomaha i ka wela nui, hoʻopaʻa i ka diuresis a hoʻihoʻi hou i ka kaulike wai i ka poʻe me ka maʻi maʻi.
Ke keu
ʻO ka hoʻohanaʻana i nā pona kiʻekiʻe loa o ka lāʻau lapaʻau e hiki ke hōʻeha i nā hiʻohiʻona e like me:
- he ʻike hoʻopuka;
- nalowale o ka ike;
- ninaki a me ka luaʻi
- nahoa
- nawaliwali nawaliwali
- nystagmus;
- edema poloka;
- hanaʻeha kaʻaila naʻau;
- hopu puʻuwai;
- dysarthria;
- nā hiamoe kakulā a i ʻole hana ʻino paha;
- nā hūnā ma ka lewa.
ʻO nā haunaele o ka puʻuwai naʻau kekahi o nā hōʻike o kahi overdose o ka lāʻau carbamazepine.
ʻO ka Therapy pili i ka lavage gastric, diuresis i hoʻokumu ʻia a me ka hoʻohana ʻana i nā sorbents. Eia kekahi, ua kuhikuhi ʻia nā kaʻina e mālama i ka hana hanu a me nā hana cardiac.
Hoʻopili pū me nā lāʻau ʻē aʻe
ʻO ka lāʻau lapaʻau ka haʻahaʻa haʻahaʻa me nā lāʻau lapaʻau, no laila inā ʻoe e hui pū ai i kahi kālā, pono ʻoe e ʻōlelo me ke kauka. ʻO kahi hoʻohana me nā CYP 3A4 inhibitors ke hoʻonāukiuki i ka hoʻonui ʻana o ka ʻike o ka mea i mua o ke koko. Inā hui pū me nā inducers o CYP 3 A 4 isoenzyme e koi ʻia, koi ʻia ka wikiwiki o ka metabolism o ka mea i hala.
ʻAʻole kuhikuhi ʻia ka hui
ʻAʻole kūpono ka paahana me nā MAO inhibitors.
ʻAʻole ia e kauoha i hoʻohui i kēia lāʻau i ka corticosteroids, nā estrogen-e pili ana i ka contraceptives a me nā mea hoʻokalakupua carbon anhydrase.
Me ka mālama pono
ʻO nā hihia liʻiliʻi wale nō, ʻae ʻia kona hoʻohana me Isoniazid, ʻo ka mea hoʻonui i ka hepatotoxicity o nā ka hope. ʻO ka hoʻohanaʻana o ka carbomazepine e hōʻemi i ka hopena o nā anticonvulsants, anticoagulants, barbiturates, waikila valproic. ʻO ka hopena o ka clonazepam a me ka pyramidone e hoʻopau i ka wā e hoʻohana ana iā lākou me ka carbamazepine. Pono e mālama pono e mālama i kēia lāʻau lapaʻau me ka glycosides cardiac.
I nā pilikia pilikia, lawe ʻia ka carbamazepine me isoniazid.
Nā kuʻina
ʻO ka hoʻoholo ʻana i ka pehea e hoʻohuli ai i ka lāʻau lapaʻau e pono e hoʻoholo ʻia e ke kauka. ʻO nā mea hoʻohālikelike Carbamazepine-Acre:
- Zeptol;
- Carbapine;
- Timonyl;
- Carbalex;
- Finlepsin Retard;
- Tegretol;
- Gabapentin.
ʻO ka Carbalex kekahi o nā kaona o ka lālani Carbamazepine.
Waihue huaʻōlelo waiho nā huaʻōlelo
Hiki ke kūʻai ʻia ia ma ka hale kūʻai kūʻai ma ke ʻano he kauka mai ke kauka.
Hiki iaʻu ke kūʻai me ke kī ʻole
Ke kūʻai aku nei i kēia lāʻau lapaʻau me ke kīpē ʻole. Hoʻonui ka paʻa lima lima i ka hopena o ka loaʻa ʻana o nā lāʻau lapaʻau kuikahi.
Pehea ka nui o ka carbamazepine
He lāʻau kūʻai ka lāʻau mai ka ʻoihana ʻo "Farmland" a me nā ʻoihana ʻē aʻe. ʻO ke kumu kūʻai o nā papa he 50 o 200 mg - mai 45 a 60 mau rubles.
Ke waiho nei i nā kūlana o ka lāʻau Carbamazepine
Pono e mālama i ka huahana ma kahi wela ma mua o 25 ° C
ʻO ka lā kau
Hiki ke mālama ʻia ka lāʻau lapaʻau no nā ʻoi aku 3 mau makahiki. Hōʻike ʻia ka lā hana ma ka pahu.
Nā ʻōmike no ka carbamazepine
Olga, 24 mau makahiki, ʻo Vladivostok
Ua pilikia wau mai ka epilepsy mai ka wā kamaliʻi a ua mālama ʻia au me ka Caramazepine mai koʻu makahiki 13. He kūpono kēia lāʻau lapaʻau, no laila ʻaʻohe hopena like, akā i kēia manawa ke hoʻolālā nei au i kahi pēpē a ʻaʻole wau ʻike i ka hana, no ka hiki ʻole ke hoʻohana. Makaʻu wau i ka hoʻonui ʻana i nā huhū, no laila e koho hou i kahi lāʻau hou me ke kauka.
Igor, 35 mau makahiki, Rostov-on-Don
I koʻu wā ʻōpiopio, ua loaʻa iaʻu nā hōʻailona mua o ka schizophrenia. ʻO ka manawa maʻamau, hoʻomau ka psychiatrist i ka lawe ʻana i ka carbamazepine. Kōkua maikaʻi nā pale, akā e hoʻopilikia nā hopena i ke ola. ʻAʻole lawe ke kino i ka lāʻau lapaʻau. Manaʻo wau e hāpai lākou i kahi koho maʻalahi aʻe.
Erofei, 45 makahiki, Moscow
Ua mālama ʻia ʻo ia no ka maʻi epilepsy post-traumatic. ʻO nā hopena ʻaoʻao mai kēia mau paila, ua hoʻoholo ʻia ke kauka e kū i kēia lāʻau lapaʻau me Timonil. He ʻoluʻolu ʻoluʻolu a ke hāʻawi ʻole ʻia i nā hopena like ʻole.
Vladislav, 35 makahiki, Kamensk
Ua mālama ʻia ʻo ia me ka lāʻau lapaʻau mai ka 13 a 19 mau makahiki. Aia kekahi mau hopena ʻaoʻao, akā ua hoʻopau loa i kēia lāʻau i ka epilepsy. ʻAʻole he kuikahi no 17 mau makahiki.
