ʻO ka Duloxetine kahi lāʻau lapaʻau e pono ai i nā hopena hōʻeha o ka neuropathy maʻi a me nā mea kaumaha ʻole aʻe. Ma muli o kāna hana maikaʻi nui, ua loaʻa kēia lāʻau lapaʻau i ka nui o nā noi hau lapaʻau.
ʻO ka Duloxetine kahi lāʻau lapaʻau e pono ai i nā hopena hōʻeha o ka neuropathy maʻi a me nā mea kaumaha ʻole aʻe.
Inoa Kūʻai ʻole honua
No ka hoʻoili waiwai ʻana a me ka kālepa.
Ka inoa hiʻona o ka pono lāʻau (γS) -N-Methyl-γ- (1-naphthyloxy) -2-thiophenpropanamine.
I ka ʻōlelo Latin: Duloxetine.
ATX
ATX: N06AX21.
E hoʻokuʻu i nā palapala a me ka ʻano
ʻO ka lāʻau lapaʻau e hana ʻia i nā kapula gelatin paʻakikī, ka uhi a me ke kino o nā mea i paʻi ʻia i ka uliuli. Aia i loko o nā pahu kuihue he microgranule spherical i loaʻa kahi ʻono waiū a i ʻole ka poni paha.
ʻO ka mea hana e hōʻike ʻia e nā endxetine. ʻO ka huaʻōlelo kōkua āu e like penei:
- huki;
- mannitol;
- kōpana;
- titanium dioxide;
- sucrose;
- laulel sulfate;
- kaona cetyl.
Hana ʻia ka pahu kohu gelatin mai ka gelatin, ka titanium dioxide me ka hoʻohui o ka ʻulaʻula polū i hoʻomalu ʻia.
Hoʻokuʻu ʻia ka lāʻau lāʻau i nā kapula gelatin paʻakikī o ka ʻulaʻula.
Ka hana lāʻau lapaʻau
Hoʻopū ka mea hana ikaika i ka hoʻomaikaʻi ʻana i ka norepinephrine, serotonin a me ka dopamine (mahele ʻokoʻa). Ke alakaʻi aku nei kēia i ka hōʻiliʻiliʻana o kēia mau neurotransmitters a hoʻonui i kā lākou hoʻouna ʻana i ka pūnaehana sentral. Hiki i ka waiwai hiki ke hoʻonui i ka paepae hōʻeha no ka ʻeha e ulu me ka neuropathy.
Lapaʻau lāʻau
Ma hope o ka lawelawe waha ʻana i ka lāʻau lapaʻau, hoʻomaka nā mea ikaika e hoʻoulu ma hope o 2 mau hola. Ma hope o nā hola 6, ua hōʻea ka nui o ka piʻi ʻana. ʻAʻole ka emi o ka nui o nā lāʻau lapaʻau i ke koko i ka wā eʻai ai, akā ʻo ka manawa e hiki ai i ka piʻi kiʻekiʻe loa ke piʻi a hiki i 10 mau hola.
ʻAʻole ka emi o ka nui o ka lāʻau lapaʻau i ka wā e ʻai ai.
Hoʻopaʻa ʻia nā mea ola e ka protein plasma. Pili ke ʻano o ke ate a me nā pōpoki i ka hana o kēia kaʻina hana. Lawe ʻia ka lāʻau lapaʻau mai ke kino o ka mea maʻi me ka urine. ʻO ka hoʻopau hapa-hapalua ke ola i 12 mau hola.
Nā hōʻailona no ka hoʻohana ʻana
Hoʻohewa ʻia ʻo Duloxetine no:
- nā ala ʻeha o ka neuropathy maʻi peripheral;
- Hōʻikeʻike
- nā ʻehaʻeha o nā ʻeha hōʻeha o ka ʻōiwi musculoskeletal (e nānā ʻia i kēlā mau syndromes me ka fibromyalgia, osteoarthritis o ke kuli o ke kuli, ka maʻi ʻeha o ke kua lalo);
- maʻi hopohopo kanalima.
Nā Hoʻohui
Wahi a nā ʻōlelo kuhikuhi no ka lāʻau, ma waena o nā contraindications:
- koki-kihi kikowaena paʻa ʻole paneʻe;
- makahiki a hiki i ke 18 mau makahiki;
- ka hemahema o ka ate (ma hope o ka lawe ʻana i 20 mg o ka lāʻau lapaʻau, hoʻonui ʻia ka lōʻihi o ka endxetine e 15% i hoʻohālikelike ʻia me ka ʻikepili helu)
- maʻi momona i loko o ka fructose;
- ka nele o isomaltase a me ka sucrase;
- glucose-galactose malabsorption;
- kahua papa o ka pilikia ʻole o ke ake;
- kaina ʻona i hala ʻole ʻia.
Me ka mālama pono
E koi ʻia ka hoʻoponopono ʻana a me ke nānā ʻana i nā kauka olakino maʻamau inā loaʻa i kekahi mau maʻi:
- hypertension intraocular;
- piʻi koʻikoʻi no ka hoʻomohala ʻana i ka pōkole pani-pani;
- maʻi maʻi bipolar and mania;
- hana ʻole a paʻa ʻole, hana ʻole i ka hana (hōʻea i ka hana 30 ml / min), hemodialysis;
- ka wā hapai i ka poʻe maʻi;
- nā manaʻo no ka pepehi kanaka a i ʻole he ho'āʻo ʻana e hana i loko o ka mōʻaukala;
- nahoa
- mahuahua ka hopena o ka hyponatremia (ma kēia ʻāpana ka nui o nā ʻelemakule, nā mea maʻi me ka cirrhosis, dehydration, syndrome o ka hemahema o ka hana antidiuretic hormone).
Pehea e lawe ai i ka ujxetine?
ʻO nā capsules o ka lāʻau lapaʻau e manaʻo ʻia no ka hoʻokō waha. Puke ʻia lākou a holoi ʻia me kahi ipu wai.
ʻAʻole pono e hoʻowalewale ʻia nā pahu gula i loko o nā capsule a hoʻohui ʻia me nā huahana a waiila paha e hana ai ka pohō.
Kuhi ʻia kēia e ka mea pono e hoʻokaʻawale ʻia ka lāʻau ma loko o ka ʻōpū. Hoʻokomo ke kapula gelic enteric e hoʻokō i kēia.
ʻO ka palena maʻamau o kēlā me kēia lā o ka lāʻau, ka mea i ukali pinepine ʻia e nā kauka, hiki i ka 30-60 mg. ʻAʻole i kēia ʻoka i māhele ʻia i kekahi mau māhele, akā e hoʻohana ʻia no ka manawa like. ʻAʻole hilinaʻi ka hoʻohana ʻana i ka lāʻau lapaʻau ma kahi hoʻokomo kai.
Wahi a ka maʻi maʻi a me ke ʻano maʻamau o ka mea maʻi, hiki ke hoʻoponopono ʻia ka nui o ka lā a hiki i ka 120 mg. I kēia hihia, pono e hoʻokaʻawale kēia laula i 2 mauosa.
Komi ʻia nā Kūpeka a holoi ʻia me kahi aniani o ka wai.
Lawe i ka lāʻau lapaʻau no ka maʻi maʻi maʻi
Ua hōʻike nā noiʻi i ka pono o ka lāʻau lapaʻau i nā hopena hōʻeha o ka neuropathy maʻi maʻi. No ka haʻalele ʻana o nā contraindications, hiki i nā mea maʻi me ka maʻi diabetes ke loaʻa i kahi maʻi maʻamau i kēlā me kēia lā.
Ehia mau lā i hōʻike ʻia?
ʻO ka hapalua o ka ola o nā mea hana ikaika a hiki i 12 mau hola.
Nā hopena ʻaoʻao o Duloxetine
I waena o nā hopena maʻamau loa mai ka lawe ʻana i ka lāʻau lapaʻau, kapa ʻia ka ʻeha, ka ʻōpū, ka ʻōpū, ka waha maloʻo, nui ka hiamoe, ke kaupaona ʻana.
I ka hapanui o nā maʻi, ua ʻike ʻia kēia mau maʻi i kahi haʻahaʻa o ka maʻi a hoʻomaka wale i ka hoʻomaka. Aia nā loli i ka helu o nā ʻohi o nā ate, ma nā hihia maʻamau, nā maʻi parasit (fungus) a me nā maʻi maʻi maʻi (laryngitis, otitis media) hiki.
ʻŌpala Gastrointestinal
Mai ka pūnaehana ʻana, ʻike nā hopena ma hope o ka lawe ʻana i ka lāʻau lapaʻau.
Ke lawe nei i ka lāʻau, hiki ke ola.
ʻOi paha ka hoʻomohala ʻana i ka gastritis, gastroenteritis, stomatitis, hepatitis, hōʻeha ate, ka ʻike ʻana o ka belching, ka lawehala ʻana o nā ʻano ʻaila.
Kuhi loa ʻike ʻia: ke hele ʻana o ke koko ma loko o ka papa, ka ʻōpū kino, ke koko a me ka jaundice.
Pūnaehana pīhoihoi waena
I waena o nā hopena maʻamau maʻamau: ka hiamoe, nā hōʻeha, ke kaumaha, paresthesia, dizziness, kaʻaiʻole, ka hopohopo, nā haʻalulu o nā poʻo, nā lethargy, ka hoʻomāinoino.
ʻO ka maʻi maʻamau, hoʻopiʻi ka poʻe maʻi i ka nui o ka huhū, dyskinesia, myoclonus, kahiʻano hiamoe, lethargy, bruxism, disorientation i ka lewa, paʻa maka.
I kekahi manawa e hoʻopiʻi nā mea maʻi i nā hana hoʻolāʻau o ka hiamoe aʻo ke lawe ʻana i ka lāʻau.
Ka huhū, hoʻonāukiuki, ka mania, nā hoʻopaʻapaʻa, nā suicidal tendencies, hopohopo psychomotor a me ka serotonin syndrome pinepine i kahi ulu.
Mai ka papa huhū
Ua liʻiliʻi nā hopena ʻaoʻao mai ka papa huhū. ʻO ka pinepine, ʻo nā maʻi e lawe ana i ka lāʻau lapaʻau e hoʻopiʻi i ka yawning. I kekahi manawa, ʻike ʻia kahi manaʻo o ka hoʻopiʻi ʻana o ka pharynx a me nā wahaebleeds.
Ma ka ʻāpana o ka ʻili
ʻO ka hopena maʻamau loa ke ʻano o ka hoʻoulu ʻana i ke kino, ʻohi.
ʻO ka liʻiliʻi maʻamau e nānā ai, ʻo ka hemorrhage subcutaneous, photosensitivity (hoʻonaninani i ka lā), urticaria, ke ʻano o ke anuanu maloʻo, contact dermatitis, Stevens-Johnson syndrome a me ka angioedema.
ʻO ka hopena ʻokoʻa maʻamau ka hoʻopau ʻana o ke kino.
Mai ka pūnaehana genitourinary
Wahi a nā ʻōlelo aʻoaʻo no ka lāʻau lapaʻau, ʻoi aku ka nui o nā nāwaliwali o ka hana erectile, nā pilikia i ka loaʻa ʻana o ka orgasm, hoʻemi i ka makemake moekolohe.
Ua ʻike pinepine ʻia ka dysuria, ka mālama ʻana i ka urinary, nocturia, intermittent urination, urinary incontinence, ejaculation disorder, genital infection, vaginal blood.
Noho pinepine loa, hiki i nā hōʻailona o ke menopause a me kahi hoʻololi i ka honi o ka urine hiki ke hele mai.
Mai ka pūnaehana cardiovascular
ʻO ka ʻōmaʻomaʻo maʻamau e hāmama ana me ka puʻuwai wikiwiki a me ka wikiwiki.
ʻOi aku kahi palupalu, nā hōʻailona o ka tachycardia, nā anuanu a me ke koko kiʻekiʻe.
I waena o nā mea kupaianaha i kapa ʻia ʻo atrial fibrillation, supraventricular arrhythmia a me ka hoʻokūkū hypertensive.
I ka wā mālama me ka lāʻau lapaʻau, ʻike pinepine nā maʻi i ka palupalu.
ʻŌnaehana Endocrine
I nā hihia pinepine, ulu nā hypothyroidism.
Mai ka ʻōnaehana musculoskeletal
ʻO ka hopena maʻamau ka hopena o ka musculoskeletal system ka hiʻohiʻona o nā ʻehaʻā o ka hooweliweli, ka ʻeha ʻana i nā io a me nā iwi, kahi ʻano paʻakikī.
Hōʻike pinepine ʻia ka twitching Muscle.
Loaʻa pinepine loa ʻo Trismus.
Allergies
Me ka piʻi o ka naʻau o ka mea maʻi i kekahi a i ʻole nā mea hou i ka hoʻopili ʻana o ka lāʻau lapaʻau, hiki i nā hōʻike kūloko. I nā pilikia pinepine, hōʻike ʻia nā hopena anaphylactic.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
I ka wā e mālama ai me ka Duloxetine, aia kahi pilikia o ka hiamoe, ka ʻae ʻana i ka hopena o ka psychomotor, a me nā hana cognitive. No kēia kumu, pono e hōʻole i nā mea maʻi e hana i kahi kaʻa a komo i nā hana eola ʻia.
Ma ka hoʻolālā ʻana o Duloxetine e haʻalele i ka hoʻokele.
Nā ʻōlelo kikoʻī
Pono ka hoʻopau ʻana i ke ʻano o ka lāʻau lapaʻau me ka hoʻohaʻahaʻa ʻana i ka nui. Inā ʻaʻole, hiki i ka hoʻolālāʻana o ka maʻi withdrawal.
Ma muli o ka hikiʻole ke hoʻemi i ka dosage i 15 mg, ʻo ka manawa ma mua o ka hoʻonui ʻana o ka hoʻokele.
Hoʻohana i ka wā hāpai a me ka lactation
I ka lāʻau lapaʻau, ʻaʻohe ʻikepili e pili ana i ka hopena o ka lāʻau lapaʻau ma ka olakino a me ka hoʻomohala ʻana o ka pūpū, no laila, ʻaʻole i hāʻawi ʻia e kuhikuhi i ka Duloxetine. ʻO nā mea kū'ē he mau mea ia e loaʻa ai ka pōmaikaʻi no ka makuahine mai ka lawe ʻana i ka lāʻau lapaʻau ma mua o ka hopena e hiki ai i ka maʻi wahine. Ke koho ʻana i ka lāʻau i ka wā lactation, pono e lactation.
Ke koho nei i kahi antidepressant no nā wahine o ka hānau ʻana o ka makahiki, pono e hōʻike ʻia ka mea maʻi e pili ana i ka pono no ka hoʻomaʻamaʻa ʻana.
Ke koho ʻana i ka lāʻau i ka wā lactation, pono e lactation.
Koho ʻana iā Duloxetine i nā Keiki
ʻAʻole i kuhikuhi ʻia ka lāʻau lapaʻau no nā keiki a me nā wā ʻōpio ma lalo o ka makahiki 18.
Hoʻohana i ka wā kahiko
ʻO ke kumukanawai o Duloxetine
ʻO ka hopena lā i kēlā me kēia lā, ʻaole ʻia, ʻaʻole i mālama ʻia e hoʻonui ʻia, ʻo 1.2 g Ke hoʻonui i kēia maʻa (me ka monotherapy a me nā mea lapaʻau ʻē aʻe) e kumu i kēia mau hōʻailona:
- nā hoʻopaʻi clonic;
- hiamoe
- serotonin syndrome;
- koma
- tachycardia;
- utuka
Ua hōʻike ʻia kahi hihia o ka overdose (dosis 3 g), e ukali ʻia e kahi hopena o ka make.
ʻAʻohe mea lapaʻau kūikawā no kēia mea ikaika, no laila ua lawe ʻia nā helu he nui e hoʻomau i ke ʻano o ka mea maʻi.
- ʻO ka hoʻomaʻemaʻe Gastric (hoʻopili i ka luaʻi) ka manaʻo inā loaʻa ka lāʻau lapaʻau i kēia manawa hou.
- ʻO ka lawe ʻana i ke kalina kahi i hoʻokaʻawale ʻia ai ka lawe ʻana mai o ka lāʻau.
- Ke hana nei i ka mālama maʻi ma muli o nā mea i hōʻike ʻia.
Hiki i kahi lāʻau lapaʻau ke hopena i kahi hiamoe.
Hoʻopili pū me nā lāʻau ʻē aʻe
Ke hui pū ʻia me nā lāʻau ʻē aʻe, pono paha ʻoe e hoʻoponopono i ka pinepine o ka hoʻokele ʻana a i ʻole ka pā ʻana.
Me nā inhibitors CYP1A2. Hoʻohāuki pinepine kēia hui ʻana i ka hoʻonui ʻana o ka manaʻo o ka mea hana i ka plasma. E mālama pono ʻia ka makaʻala me ka wā e hui pū ai me Tolterodine a me Desipramine.
Me nā antidepressants ʻē aʻe. ʻAʻole i'ōlelo ʻia ka Co-hoʻokele, me ka lāʻau ʻo Paroxetine. Ke alakaʻi nei kēia i kahi emi i ka hoʻomaʻemaʻe.
Me nā inhibitors MAO, Moclobemide. ʻAʻole pono ka noi ʻana, ma muli o ka hiki ʻana o ka hoʻopaʻi ʻana o ka naʻau, hyperthermia, coma, myoclonus. I nā pilikia koʻikoʻi, hiki nō ke make.
Me nā benzodiazepines, ethanol, nā lāʻau lapaʻau antipsychotic, phenobarbital. ʻAʻole kuhikuhi ʻia nā ʻano like ʻole.
Me nā mea hoʻohui antiplatelet a me nā anticoagulants. I kēlā mau hihia, he hiki ke hoʻokahe. Ma hope o ka lawe ʻana i ka lāʻau lapaʻau me Warfarin, hiki ke hoʻonui nui aʻe ma INR.
Pono e mālama ʻia i ka wā e koho ai i kahi antidepressant me ka clomipramine, nā welo a St. John, pethidine, triptanam, Amitriptyline, Venlafaxine a me Tramadol, Zinnat.
ʻAʻole i hoʻohui pū ʻia ka clotrimazole i nā loli i ka hana.
Hoʻolaha ka waipuna
No ka manawa o ka mālama ʻana me Duloxetine, pono ʻoe e hōʻalo i ka inu ʻana i ka mea inu ʻawa. A i ʻole, aia kahi pilikia nui o nā hopena like ʻole.
Nā kuʻina
Hoʻohālike nā lāʻau like me ka hana a me ka hana Duloxetine Canon a me Symbalta.
ʻO nā huaʻala like nā hopena like ʻole:
- Deprim forte;
- Venlaxor;
- Gelarium Hypericum;
- Trittiko;
- Velaxin;
- Xel;
- Amitriptyline;
- Hoʻolālā.
Hōʻike ʻia kēlā me kēia lāʻau lapaʻau e nā mea ikaika a me nā hiʻohiʻona o ka hoʻohana. No kēia kumu, pono ʻoe e nīnau i kāu kauka ma mua o ka hoʻololi ʻana i kahi lāʻau.
ʻO ka lāʻau lapaʻau like like ʻo Symbalta.
Waihue huaʻōlelo waiho nā huaʻōlelo
Wahi a nā ʻōlelo kuhikuhi no ka hoʻohana, loaʻa kēia lāʻau lapaʻau ma ka papa inoa.
Hiki iaʻu ke kūʻai me ka loaʻa ʻole o ka hōʻailona?
Ka ʻae ʻana i ka Duloxetine ʻaʻohe ʻōpole ua pāpā ʻia ʻole.
Kūʻai Duloxetine
Kuhi ʻia ke kumukūʻai o ka lāʻau lapaʻau i ka nui o nā kapsul i kahi pā.
Ma nā wahi kūʻai ma Moscow, nā kumukūʻai kumukūʻai:
- 14 mau kōlea (30 mg) - 1000 rubles;
- 28 mau pahu (60 mg) - 2100 mau rubles.
Ke waiho nei i nā kūlana no ka lāʻau lapaʻau
Nā pono e mālama ai: ka mahana + 15 ... + 25 ° C, ka nele o ka lā mamao a me ka māla.
ʻO ka lā kau
Kuhi ʻia nā rula mālama, hiki ke hoʻohana ʻia nā kapaka no 3 mau makahiki mai ka lā i hoʻokuʻu ai.
Mea hana
ʻO ka mea hana o kēia huahana lapaʻau ka Canonfarm Production CJSC. Aia ka hui ma kahi kikowaena o Moscow (Schelkovo).
Aia he mau hui ʻē aʻe e hana ana i ka lāʻau. I waena o lākou ʻoihana ʻo Glenmark.
Nā Hōʻike Manaʻo Duloxetine
Hoʻomaʻamaʻa maikaʻi nā kauka i kēia lāʻau lapaʻau, ka mea i wehewehe ʻia e ka hoʻokūkū kiʻekiʻe a me kahi ākea ākea. Nui nā poʻe maʻi e hauʻoli pū ana me ka lāʻau.
Kauka
Olga, neurologists, ʻike lāʻau lapaʻau 13 makahiki, Moscow.
ʻO ka maikaʻi o kēia lāʻau lapaʻau kona hopena e kūlike i ka ʻehaʻeha o nā ʻano etiology. He kūpono no nā maʻi i ka maʻi maʻi. ʻAʻole i kuhikuhi pinepine ʻia e ia he antidepressant, no ka mea aia nā mea maʻalahi i nā lāʻau lapaʻau kūpono. ʻO ka mea nele i ka uku no nā kumukūʻai nui loa, no ka mea, ua koi ʻia ka lōʻihi ma mua.
Hoʻomaʻi pinepine, nā poʻe maʻi e lawe ana i ka lāʻau lapaʻau e hoʻopiʻi i ka yawning.
ʻO nā maʻi maʻi
Nikolay, 40 makahiki, ʻo Tyumen
Ua kuhikuhi ʻia ʻo Duloxetine e ke kauka ma muli o ka hoʻonui nui ʻana o ke kaumaha. I kekahi mau lā ma ka hoʻomaka ʻana o ka papa ua kūleʻa iki wale nō, akā ʻaʻole kuhi ʻia ka mālama ʻana. Ma hope o kekahi mau lā, ua nalo loa ka hopena ʻaoʻao. Ua kiʻekiʻe ke kumukūʻai, akā ʻoi aku ka maikaʻi o ka lāʻau lapaʻau ma mua o nā koina lāʻau, no laila ua kūpono nā uku.
