ʻO Rosucard e pili ana i nā statins e hoʻohaʻahaʻa pono i ka neʻe o ka kolamu ma ke kahe koko. ʻO ka inoa inoa kūʻai honua ʻole o ka lāʻau ʻo Rosuvastatin (Rosuvastatin).
Hoʻomaʻamaʻa ka lāʻau lapaʻau ma ka mālama ʻana i ka hypercholesterolemia, ka pale ʻana i ka hoʻokumu ʻia ʻana o nā pli atherosclerotic a me nā pathologies cardiovascular. Ke hoʻoholo nei ke kauka i ka dosis o ka lāʻau lapaʻau e pili ana i ka nui o ka maʻi a me nā ʻano pilikino o ka mea maʻi.
Aia ka 'atikala pili i ka ʻike pili e pili ana iā Rosucard (10.20.40 mg), kona kumukūʻai, loiloi ka hoʻomanawanui a me nā analogues.
ʻO ke ʻano a me ka ʻano hana o ka lāʻau lapaʻau
Hōʻike ʻia ʻo Rosucard i kahi lāʻau lapaʻau e loaʻa ai ka hopena lipid-lowing. Hoʻopau ka mea hana i ka hana o HMG-CoA reductase. Mahalo i kēia enzyme, ua hoʻohuli ʻia ka HMG-CoA i ka acid mevalonic, kahi mea i mua o ka cholesterol.
Ke hoʻomau nei ka ʻoihana hoʻokaʻawale kikowaena ʻo Zentiva i ka lāʻau lapaʻau. Ua hoʻohua ʻia ʻo Rosucard i ka puka pākuʻi ʻoniʻoni no ka hoʻohana ʻana i ka waha. He kukui polū ke kala he, he convex papa ma nā ʻaoʻao ʻelua a me kahi ʻano elongated.
ʻO ka hana ikaika o ka lāʻau ʻo rosuvastatin. 1 papa o Rosucard ka mea he 10, 20 a 40 paha mau mea ikaika. Eia kekahi i kēia, ʻo ka lāʻau lapaʻau e hoʻokomo i nā mea kōkua, ʻo ia hoʻi:
- tiole kūpapa;
- mikulamulamina selulose;
- lactose monohala;
- paʻahau magnesium.
Aia ka kiʻi i nā mea like me nā talc, macrogol 6000, red oxide, hypromellose a me ka titanium dioxide.
Hoʻokahi ka pahū he 10 papa. Hoʻopaʻa ʻia ka ʻekala. Hoʻopili pinepine ʻia ka ʻōpiopio Rosucard i kahi pepa hoʻohui no ka hoʻohana ʻana i nā papa.
Ke 'ano o ka hana o ka hana nui
Hāpai ka hana a rosuvastatin e hoʻonui i ka pae o ka ʻĀina LDL ma loko o nā pūpuna o ka parenchyma ate (hepatocytes). ʻO ka hoʻonui nui aʻe o kā lākou helu e hoʻopiʻi i ka hoʻonui ʻana i ka hoʻāla a me ka wehe ʻana o ka LDL, kahi hoʻohaʻahaʻa i ka hoʻokumu ʻana o VLDL a me ka nui o nā kikoʻī o ka "hewa" kolesterol.
ʻO ka hopena lipid-hoʻohaʻahaʻa i ka Rosucard e hilinaʻi pololei i ka dosis i lawe. Ma hope o 1 pule o ka lawe ʻana i ka lāʻau lapaʻau, mālama ʻia kahi hōʻemi i ka pae o ka cholesterol, ma hope o 2 hebedoma 90% o ka hopena nui loa o ka hopena therapeutic. Ma ka wiki 4, ua ʻike ʻia ka hoʻokū ʻana o ka hoʻoilo ʻana o ka cholesterol ma kahi pae kūpono.
E kōkua ana ka lāʻau lapaʻau e hoʻonui i nā pae HDL, ʻaʻole ia ma ka atherogenic a ʻaʻole i waiho ʻia i loko o nā ʻano o nā pāla a me nā mea e ulu ana ma nā paia o nā arteri.
ʻAʻole loli nā intake i kēlā me kēia lā i nā hiʻohiʻona pharmacokinetic. Hoʻopili ka mea kanu me nā kahe koko (ma ka liʻiliʻi o ka mea e hoʻopili ai i ka albumin), i hana ʻia nā kinipona ma o ka pehu. Hiki i kekahi mea ke hele i ka pleka.
Ma kahi o 90% o ka rosuvastatin i lawe ʻia mai ke kino ma o nā ʻalā, ʻo ke koena ma o nā keiki. ʻAʻole hilinaʻi ka pharmacokinetics o ka mea hana i ka wahine a me ka makahiki.
Nā hōʻailona a me nā contraindications no ke hoʻohana
Ua kuhikuhi ke kauka iā Rosucard inā pili ke ka maʻi o ka mea maʻi me ka nui o ka cholesterol.
Ke pāpā ʻia nei ka lāʻau lapaʻau ponoʻī.
Nui nā ala palaki kahi e hiki ʻole ai i ka lipid metabolism ka hana.
Hoʻohana ʻia ka hoʻohana ʻana i nā papa.
- ʻO ka hypercholesterolemia mua a i ʻole.
- ʻO ka hoʻomaʻamaʻa paʻakikī o hypertriglyceridemia.
- Familial (hoʻoilina) homozygous hypercholesterolemia.
- Ke hoʻolōʻihi nei i ka hoʻomohala ʻana o ka atherosclerosis (hoʻohui i ka ʻai).
- ʻO ka pale ʻana i nā pilikia cardiovascular e pili ana i ke kua ʻana o ka atherosclerosis (ka maʻi naʻau, ka maʻi hypertension, ka ʻeha a me ka ʻeha o ka naʻau).
Hoʻohana ʻia ka hoʻohana ʻana i kahi lāʻau lapaʻau me ka maʻa o 10 a 20 mg i:
- ka heleʻana o kēlā me kēia manaʻo;
- ka lawe ʻana i kahi keiki a i ka pale umauma;
- aole i hiki aku i na makahiki 18;
- ka hoʻomohala ʻana o ka myopathy (maʻi neuromuscular);
- Hoʻolaha laha me ka cyclosporine;
- hoonui o ka hana o ka paina CPK i ka ʻoi aku ma mua o ʻelima mau manawa;
- ʻo ka hōʻole ʻana i ka wahine i ka ʻoluʻolu kūpono;
- ake aho a me ka hana o ke aʻalolo pūpū hana;
- ka hoʻokō paʻa ʻana o nā pā o ka protein protease.
Aia kekahi papa inoa o nā contraindications ʻano no ke kau ʻana o ka 40 mg:
- E pili ana i ka uluʻana i ka myopathy.
- Ka maʻi waʻawa a me ka inu ʻawaʻawa.
- ʻO ka male ʻole o ke ʻano i haʻi ʻia.
- ʻO Myelotoxicity e lawe ana i ka HMG-CoA reductase blockers a hoʻoulu.
- ʻO kou hana hina thyroid.
- Hoʻohana hoʻohui i nā fibrates.
- Nā ʻano maʻi ʻē aʻe e pili ana i ka hoʻonui ʻia ʻana o ka rosuvastatin i ke kahawai.
ʻAʻole ia e kauoha ʻia e hoʻohana i kahi waihona o 40 mg na nā ʻelele o ka lāhui Mongoloid ma muli o ka hiki o nā ʻano kū hoʻokahi.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
ʻAʻole pono nā papa ʻaina e kahakaha ʻia a ʻōmaʻomaʻu, ʻu ʻia lākou i ka wai. ʻO ka lawe ʻana i ka lāʻau lapaʻau, ʻaʻole ia i hilinaʻi i ka manawa o ka lā a me ka ʻai ʻana o ka meaʻai.
Ma mua o ke kuhikuhi ʻana iā Rosucard, kuhikuhi ikaika ke kauka e pili ana ka mea maʻi i ka ʻai e kuhikuhi ana i ka hoʻemi ʻana i ka nui o ka ʻai o ka cholesterol.
ʻO ka dosage pākahi o kēlā lā i kēia lā he 0.5-1 mau papa (5-10 mg). Ma hope o nā pule he ʻehā, hiki ke hoʻonui ʻia ka nui e ka kauka. Hiki ke hoʻonui iki i kēlā me kēia lā i 40 mg hiki ke loaʻa wale i ka kolamu nui loa a me ka hopena kiʻekiʻe o nā ʻōpiopio o nā maʻi cardiovascular, ma ke ʻano o kēlā me kēia lā o 20 mg ʻaʻole i like ʻole.
Hōʻike ka papa ma lalo nei i nā hiʻohiʻona o ka hoʻohana ʻana o Rosucard i ka poʻe o ka lāhui Mongoloid, me nā mākaʻi o ka sistema biliary a me ka maʻi neuromuscular.
Nā maʻi / ke kūlana | Nā hiʻohiʻona o ka lawe ʻana i nā paila |
ʻO ka hana hema ʻole | Ināʻoi aku i kahi o 7 mau pono, pono ia e hoʻoponopono i ka hopena o ka lāʻau. |
ʻO Renal hiki ʻole | ʻO ka dosage ka 5-10 mg i kēlā me kēia lā. Me kahi awelika haʻahaʻa, 40 mg i kēlā me kēia lā ʻaʻole pono e hoʻopau, me ka loaʻa ʻole o ka maʻi koʻikoʻi, ʻāpā ʻia ka rosuvastatin. |
E ʻikea i ka myopathy | Hiki i nā mea maʻi ke lawe i ka 10-20 mg o ka lāʻau. Hoʻokomo ʻia kahi dosis o 40 mg i kēia predisposition. |
Lele Mongoloid | ʻO ke ʻano maʻamau o kēlā me kēia lā he 5-10 mg. Hoʻopili paʻa ka hoʻonui ʻana i ka dosage. |
ʻO 24 ka malama o ke pale ma hope o kēia manawa, ʻo ka lawe ʻana i ka lāʻau lapaʻau i pāpā ʻole ʻia. Mālama ʻia ka pale mai nā keiki liʻiliʻi ma kahi wela o 25 ° C.
ʻO nā hōʻike hewahewa a me ke keu
Hiki ke hele mai kahi hopena i ka wā e lawe nei i ka lāʻau lapaʻau.
Inā hele hewa, hiki i ka mea maʻi ke ho'ōki i ka hoʻohana ʻana iā Rosucard a kūkākūkā me kahi olakino olakino.
ʻO nā hopena ʻaoʻao ka hilinaʻi pololei ʻana i ka dosis o ka lāʻau, no laila, ʻike pinepine ʻia ia ma muli o ke alakaʻi ʻana o nā papa me kahi dosis o 40 mg.
Aia nā ʻōlelo i hōʻike i kēia ka ʻike pili e pili ana i nā hanana ʻino.
- ʻO nā maʻi ʻo Dyspeptic - hōʻeuʻeu i ka paila a me ka luaʻi, ka ʻeha ma ka ʻāina epigastric, i kekahi manawa ka hoʻomohala ʻana o ka pancreatitis a me ka hepatitis.
- Nā huakaʻi Genitourinary - proteinuria (mua o ka protein i ka urine), hematuria (ke kahe koko i ka urine).
- Hōʻike Allergic - kaʻeha, rashes ma ka ʻili, urticaria.
- ʻO nā maʻi o ka musculoskeletal - nā hōʻeha o ka ʻōpū, ke ōkīkī o ka iwi māla, ka luku ʻana i nā hana o nā mākala.
- Disfunction CNS - migraine nūhou, nāwaliwali, nā hiamoe hiamoe a me nā ahiahi pōkole, nā kaumaha.
- Hōʻalolo i nā kino hana hua - ka ulu o nā kelima mammary i nā kāne.
- ʻO ka ʻili a me ka hoʻonaninani kūmākia ka maʻi o ka ʻvenslelo Stevens-Johnson (a i ʻole derrotitis necrotic).
- ʻO ka hoʻonāukiuki i loko o ka ʻoihana endocrine - ka hoʻomohala ʻana o ka non-insulin-dependant diabetes mellitus type II.
- Hōʻalo ʻole - ka uahi maloʻo a me ka pau o ka hanu.
No ka mea, ʻaʻole i hilinaʻi ʻia ka pharmacokinetics o ka mea hana ikaika, ʻaʻole nui ka hanana overdose. ʻO kekahi manawa hiki ke hoʻonui i nā hōʻailona o ka pili ʻino.
ʻO ka Therapy kekahi mau hana e like me ka gastage lavage, ka hoʻohana ʻana i nā sorbents a me ka hoʻopau ʻana i nā hōʻailona.
Ka kuʻikahi me nā lāʻau lapaʻau ʻē aʻe
ʻO ka hoʻokūkū o Rosucard me kekahi mau lāʻau lapaʻau hiki ke alakaʻi i kahi hoʻohaʻahaʻa a i ʻole hoʻi e hoʻohiki i ka maikaʻi o ka waihona ikaika, a me ka hopena o nā hopena ʻaoʻao.
I mea e pale ai iā ia mai nā hopena maikaʻi ʻole, pono ka mea maʻi e hoʻomaopopo i ke kauka e pili ana i nā maʻi āpau a me nā lāʻau lapaʻau i lawe ʻia.
ʻO ka papa aʻe kahi i loko o kahi papa inoa o nā lāʻau lapaʻau i ka manawa o ka hoʻokahuli i hoʻonui ʻia a hōʻemi paha i ka hopena therapeutic o Rosucard.
Hoʻonui i ka hopena | Hoʻemi i ka hopena |
Cyclosporin (kahi immunosuppressant ikaika). ʻO ka waikawa Nicotinic ʻO nā pale o ka protein protease. Nā mea hoʻohālikelike. Nā Gemfibrozil a me nā mea ʻē aʻe. | Erythromycin (kahi lāʻau lapaʻau mai ka papa macrolide). ʻO nā Antacids, e pili ana i ka alumini a me ka magnesium hydroxide. |
Aia kekahi ʻike e hiki me ka hoʻohana paʻa o ka Rosucard me Warfarin a me nā mea hoʻonaʻamau vitamin K K a pau, hiki i ka hiki ke hoʻemi i loko o INR.
I ka papa o nā hoʻokolohua ʻepekema, ʻaʻohe ʻike kino i ʻike ʻia ma waena o nā māhele o Rosucard a me Ketoconazole, Fluconazole, Itraconazole, Digoxin, Ezetimibe.
Lā ʻia iā ia ka lawe ʻana i ka lāʻau a me ka waiʻona i ka manawa like. ʻO ke pale ʻana i ka waiʻona a me ka ulaula e kōkua i ka hoʻohaʻahaʻa i ka kolesterol i kahi kiʻekiʻe i ʻae ʻia.
ʻO ka uku a me ka manaʻo hoʻomanawanui
ʻO ka mea hoʻohā ia ʻo Rosucard, ua nui ke kumukūʻai. ʻOiai ke kūpono o ka lāʻau lapaʻau, ke kūʻai mau nei kona kumukūʻai nui.
I ka awelika, hiki ke kūʻai ʻia ʻo Rosucard 10 mg (30 mau papa) i ke kumu kūʻai o 595 rubles, 20 mg no 875 rubles, 40 mg no 1155 mau rubles. E mālama i kāu kālā, hiki iā ʻoe ke kau i kahi kauoha ma ka pūnaewele ma ka pūnaewele o ka ʻelele hui.
Hoʻomaopopo ka hapanui o nā maʻi i ka hopena therapeutic maikaʻi mai ka lawe ʻana i ka lāʻau lapaʻau. ʻO nā mea hoʻolimalima koʻikoʻi kahi palapala hoʻoponopono kūpono a me ka pono e hoʻohana wale no 1 manawa i kēlā me kēia lā.
Eia nō naʻe, ʻike maikaʻi ʻia nā loiloi ʻino o nā mea maʻi ma ka Pūnaewele.
Hoʻokomo nā Therapist a me cardiologists i nā hopena maikaʻiʻole loa me nā dosis nui o ka lāʻau. ʻO ia ka ʻōlelo a ke kauka N.S. Nā Kauʻima:
"Ua loiloi au i ka hopena o kēia ʻano generic - ke hoʻomau nei ʻo ia i ka hana lipid metabolism i nā hana ʻole stenotic a me nā hana liʻiliʻi, ʻoi aku ka uku maoli, ma ka hoʻohālikelike ʻana me Krestor synonym. He mau hopena hopena, akā haina loa ia.
ʻLelo a me nā kikoʻi o ka lāʻau lapaʻau
I nā hihia i pāpā ʻia ai ka mea maʻi e lawe iā Rosucard ma muli o nā contraindications a ʻaoʻao paha, ke koho ke kauka i kahi mea pono.
Ma ka mākeke pharmacological hiki iā ʻoe ke loaʻa i nā ʻano like like o ka lāʻau lapaʻau, ka mea i loaʻa i ka pūnaehana like. I waena o lākou:
- Rosuvastatin;
- ʻOkaʻohana
- Rosistark;
- Kauoha
- Akorta;
- Roxer;
- Rosart
- Mertenyl;
- Rosulip.
Aia kekahi mau loina i ʻokoʻa i ka manaʻo o ka mea hana, akā aia i loko o ka hui o statins:
- Zokor.
- Nā mea kokoke.
- Vasilip
Zokor. Hoʻohui ʻia ka simvastatin ʻano hana, e kāohi ana i ka HMG-CoA reductase. Hana ʻia e nā hui lāʻau lāʻau o nā USA a me Netherlands. ʻO ka kumukūʻai maʻamau o ka ʻeke pūpū (No. 28 10mg) ʻo 385 mau rubles.
Nā mea kokoke. ʻO kēia kahi kikoʻī haʻahaʻa o Rosucard, no ka mea ke kumukūʻai o ka pale (No. 30 10mg) ʻo 330 mau rubles. ʻO ka mea hoʻonaninani ka atorvastatin, ka mea e hoʻonui ai i ka hana o nā mea LDL e kū nei i loko o nā poupona a me nā ʻoihana extrahepatic.
Vasilip. Aia ka lāʻau i ka simvastatin i loko o kahi waihona o 10,20 a 40 milligrams. Loaʻa ia nā hōʻailona a me nā contraindications e like me Rosucard. Hiki ke kūʻai ʻia ka lāʻau lapaʻau no 250 rubles wale nō (No. 28 10mg).
E pili ana i nā lāʻau lapaʻau e pili ana i ka rosuvastatin i loko o ke wikiō i kēia ʻatikala.