ʻO Maninil kekahi o nā ʻelele o ka papa o ka papaʻaina kōkē i hana ʻia e mālama ai i ka pae o ka glucose i koi ʻia i loko o ke koko.
ʻO nā lāʻau e loaʻa ana mai ka pūʻulu o nā derivatives o sulfonylurea, kuhikuhi pinepine ʻia ka lāʻau lapaʻau Maninil.
Ke hāʻawi nei ka lāʻau lapaʻau hou i kahi mea maʻi me ka maʻi maʻi āpau i nā ʻano lāʻau lapaʻau no ka mālama ʻana.
Kahi ʻia ke ʻano o kekahi ʻano lāʻau i ka mea e kau nei i ke kauka.
Koho ke kauka i ka lāʻau lapaʻau ma hope o ka ka nānā ʻana i kahi ʻike kikoʻī o ka ʻike a ka mea maʻi i loaʻa i ka wā o ka hoʻokolokolo.
Nā hua kō o ka sulfonylurea
ʻO nā lāʻau lapaʻau hou i ʻōlelo ʻia e hoʻopau ai i nā hōʻailona a hoʻoponopono i ke kiʻekiʻe o ka glucose koko i ke ʻano type diabetes diabetes mellitus i hoʻokaʻawale ʻia i loko o kahi nui.
- nā mea lawelawe e hoʻomaikaʻi i ka insulin pioni pancreatic
- nā lāʻau e hoʻonui ai i ka hoʻowalewale o nā cell i ka insulin komo ʻana, ʻo ia hoʻi, e hoʻomaikaʻi i kona hopena ma ka cell cell levelочном
- nā lāʻau lapaʻau e pale i ke komo ʻana o nā huamona e hiki mai ana ma nā ʻōpū.
Hoʻohana ka koho o ka lāʻau lapaʻau me ke kauka e komo ana, ka mea e kuhikuhi pono i kahi lāʻau lapaʻau kūpono i kēlā me kēia maʻi (a i ʻole kekahi i kekahi me ka ʻoihana paʻakikī).
I waena o nā lāʻau lapaʻau i hiki ke hoʻonui i ka hana o ka insulin hormone e ka pancreas, ʻo ka mea mua, he mau huaʻala a sulfonylurea. I ka hapanui pinepine, hoʻohana nā mea lapaʻau kūikawā i kēia mau lāʻau lapaʻau no ka mālama ʻana:
- E pili ana i ka waiwai hana, glibenclamide (Maninyl). ʻO kāna mea i kaulana nui ʻia ʻo nā papa Maninil.
- Ma lalo o ka hopena o gliclazide (tabletted drug Diabeton MV).
- Me ka papa hana nui o ka glycidone, aia i loko o nā papa Glurenorm.
- Me ka glimepiride hoʻōlaʻike (Amaril).
Hoʻomaopopo ka hopena therapeutic koʻikoʻi i ka maʻamau o ke kaila o ke kō, ma muli o ke ʻano o ka hoʻoulu ʻana o ka pancreas e hua ai ka nui o ka insulin hormone.
Pono e hoʻolilo i ke kino o kēlā me kēia kanaka, hiki ke hōʻike ʻia i nā ʻano like ʻole ma ka hopena o ka hopena lapaʻau i ʻae ʻia. ʻAʻole hiki ke haʻalele ʻia kahi hopena maikaʻi.
ʻO ia ke kumu, kahi loea lapaʻau, e pili ana i ka ʻike e pili ana i ka hoʻomohala ʻana o nā maʻi o kēlā me kēia maʻi, e koho ana i kahi koho kūpono loa nona.
ʻO nā lāʻau lapaʻau o Maninil
Hoʻohana pinepine ʻia ka lāʻau lapaʻau Maninil no ka maʻi diabetes o kahi ʻano kūʻokoʻa i ka insulin a ua hoʻokomo ʻia i loko o ka hui o ka hui o ka luaʻoniʻi lua.
ʻO ka hana ikaika o kēlā papa he māhele ia o ka glibenclamide. ʻO ka pūnaehana o ka lāʻau Manin e loaʻa i nā ʻano kōkua kōkua ʻaʻole i loaʻa kahi hopena therapeutic i haʻi ʻia.
ʻO nā mea nui o ka lāʻau lapaʻau ka hōʻike i nā hopena pacreatic a me ka extrapancreatic effects.
Ke hana nei kēia mau kaʻina hana i ke kino, inā e pili ʻoe a lawe iā Maninil:
- ke hoʻoikaikaʻana o ke kaʻina o ka hana i ka insulin e nā beta beta o ka pancreas e hoʻomaikaʻi
- aia kahi pale o nā kaʻina o ka gluconeogenesis a me ka glycogenesis i loko o ka ate,
- ka uluʻana o ka maikaʻi o nā selela a me nā ʻolua no ka insulin i hana ʻia.
ʻO ka wehewehe ʻana o ka lāʻau lapaʻau e hōʻike ana ʻo Maninil, ma hope o ka hoʻokūkū waha, ua komo koke ʻo ia i loko o kahi ʻōpū. Eia nō naʻe, ʻaʻole hilinaʻi ka wikiwiki o kēia kaʻina hana i nā kau kai a me ka nui o nā meaʻai i loko o ka ʻōpū.
Loaʻa ka lōʻihi o ka ʻai o ka ʻāwili o ka hana ikaika i ka plasma koko ma kahi o ʻelua a me ka hapa mau hola ma hope o ka hoʻohana pono ʻana i ka lāʻau.
Loaʻa ka lāʻau lapaʻau i ka papa paʻi i loko o nā ʻano like ʻole, hiki iā ia ke:
- Maninyl 1.75 mg;
- Maninyl 3,5 mg;
- Maninil 5 mg.
ʻO ka helu, i hōʻike ʻia ma ka inoa o ka papaʻa, e hōʻike ana i ka nui o nā mea hana i hoʻohui ʻia i hoʻokahi papa. Wahi a ia, ʻoi aku ka nui o ka nui o ka nui o ka lāʻau, ua ʻoi aku ka ikaika o ka hypoglycemic a me ka hopena anti-diabetes.
Hiki ke hoʻohana ʻia nā ʻōmole no ka hoʻohana ʻana i ka lāʻau - maʻi mellitus o kahi ʻano kūʻokoʻa o ka insulin e like me ka monotherapy a i ʻole me nā lāʻau hoʻohaʻahaʻa a me nā haʻalulu a me ke ʻano ʻole, he mea ʻole ka hopena o ka sulfonylurea a me nā lāʻau pālolo, hiki ke hāpai ʻia i ka mālama ʻana i ka meaʻai a me ka hana kino kūlohelohe.
Nā ʻōkuhi no ka hoʻohana ʻana i nā papa
Pono ka mania papa no ka maʻi maʻi e like me ka papa kikoʻī i kuhikuhi ʻia e kekahi lāʻau lapaʻau.
Hoʻolālā ʻia ka nui o ka lāʻau no kēlā me kēia kanaka ma muli o ka nui o ka hoʻomohala ʻana o ka hana pathological, ka nui o ka glucose i loko o ke koko ma mua a ma hope o ka ʻai, ma kahi ʻōpū ʻole, kahi ʻano makahiki o ka mea maʻi a me nā ʻano pilikino.
Ma mua o ka lawe ʻana i ka lāʻau lapaʻau, haʻi ka ʻōlelo aʻo i ka pono no ke aʻo mua ma mua.
Hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau no ka maʻi maʻi mahele penei:
- ʻO kahi lāʻau lapaʻau (hoʻokuʻu i ke ʻano a me nā dosage he 1.75 mg) i nā manawa mua o ka mālama therapeutic, pono pono e lawe i hoʻokahi a i ʻelua papa i hoʻokahi manawa. Inā, ma hope o ka lūlū o ka manawa, ʻaʻole i lawe mai kēia pūʻulu o nā lāʻau lapaʻau i ka hopena i makemake ʻia a me ke ʻano o ka normalization o nā pakanui kalepa e nānā ʻia, hiki ke hoʻonui ʻia ka dosage. ʻO ka hoʻonui ʻana i nā pehu e pono e lawe ʻia ma ka liʻiliʻi mai nā lā mai i hoʻokahi pule. ʻAʻole eʻoi aku ka nui o ka nui o ka lāʻau lapaʻau i kēlā me kēia lā no 10,5 mg o ka mea ikaika.
- ʻO Maninyl 3.5 mg, e like me ka ʻōlelo ʻana i nā ʻōlelo aʻo, e hoʻohana pinepine ʻia inā ka huina o nā papa i ka nui o ka 1.75 mg ma mua o ʻekolu mau ʻāpana i kēlā me kēia lā. Hoʻomaka ʻia ka hoʻomaka ʻana i hapalua a i hoʻokahi papa paha i ka lā. Ma hope o kēlā, ua hoʻoholo ka mea lapaʻau e pono ai i ka hoʻoponopono o kēia hana o ka mālama ʻana. ʻAʻole eʻoi aku ka nui o ka nui o ka lāʻau lapaʻau i kēlā me kēia lā no 10,5 mg o ka mea ikaika.
- ʻO ka maninil 5 papa ke loaʻa ka nui loa o nā mea ikaika i kā lākou mea hoʻonohonoho. ʻO ke ʻano o ka noi a me nā maʻi ma nā hopena mua o ka mālama ʻana he hapalua a hoʻokahi papa paha i ka lā. Ma hope iki, i ke alo ʻole a i ʻole nā hopena o ka hopena, hiki nō ke hana i nā loli i kēlā ʻano regimen. ʻO ka palena loa o kēlā me kēia lā o ka lāʻau Maninil 5 (nā ʻōlelo aʻo) ʻaʻole pono eʻoi aku ma mua o 15 mg o ka mea ikaika.
Lawe ʻia ka papa papa me ka liʻiliʻi liʻiliʻi o ka wai ma mua o ka hoʻomaka ʻana i ka pāʻina. Inā ma mua ke ʻano o ka mea maʻi e hoʻohana ai i kekahi lawehala e hoʻohaʻahaʻa i ke kō, pono e hoʻomaka ʻia ka mālama ʻana me nā ala liʻiliʻi. Inā ʻaʻoleʻoi aku ka lāʻau maʻamau i kēlā me kēia lā hoʻokahi a ʻelua mau papa, lawe ʻia ka lāʻau lapaʻau i ke kakahiaka. I nā ʻoi aʻe o ka nui, pono ke hoʻokaʻawale ʻia ka lāʻau i ʻelua - i ke kakahiaka a i ke ahiahi.
Inā lawe ʻoe i ka lāʻau lapaʻau a ʻaʻole iʻoi aku i nā kau i kuhikuhi ʻia, hiki iā ʻoe ke hōʻemi i ka ʻāʻī o ka hypoglycemia.
ʻO ka hōʻike ʻana o nā hopena maikaʻiʻole
Ke kuhikuhi nei i ka hoʻohana ʻana iā Maninil e hiki i ka lawelawe kūpono ʻana o ka lāʻau lapaʻau hiki ke alakaʻi i ka hoʻomohala ʻana o nā ʻano ʻike like ʻole, ʻo ia nā hopena.
Hiki i nā ʻokoʻa ma ka hana maʻamau o nā ʻokoʻa āpau a me nā ʻōnaehana hiki ke kū me ka pinepine o ka nui a me ka paʻakikī.
ʻO ka hōʻike ʻana o kekahi mau hopena kūpono ka mea e kū pono ana i nā hiʻohiʻona pilikino o ke kino o ke kanaka maʻi.
ʻO nā huaʻōlelo maikaʻi ʻole e loaʻa:
- ka hōʻike ʻana i ka hana o ka hāliʻi ʻana ka mea i hōʻike ʻia i ke ʻano o ka kaumaha i loko o ka ʻōpū, ʻeha i loko o ka ʻōpū, ka ʻoni metallic i loko o ka ʻōpū o ka waha, belching, hōʻea, ka luaʻi a i ʻole ke kala ʻana,
- hiki i ka ʻōnaehana keu ke pane aku i ka hoʻomaka ʻana o ka hoʻomaka ʻana i ka hana lapaʻau i ke ʻano o ka purpura, nā hōʻeha o ka ʻili a i ʻole urticaria, hoʻonui i ke kiʻekiʻe o ka photosensitivityꓼ
- nā hopena maikaʻi ʻole mai ka ʻōnaehana kaomi i nā hōʻailona ma hope nei - thrombocytopenia, hemolytic type anemia, leukopenia, erythropenia,
- hiki i nā pilikia me ke hana ponoʻī ke hoʻomaka a hoʻomohala ʻia nā maʻi e like me ka hepatitis
- ke koho pono ʻana o ka make ʻana o ka lāʻau lapaʻau ke alakaʻi i ka hooulu o ka hypoglycemia, kona mau hōʻailona nui ke ʻano o ke ʻano maʻi, ka luhi, nā lūlū, nā lima haʻalulu, ka manaʻo ākea o ka luhi me ka nui o ke hiamoe,
- kahi hoʻonui kiʻekiʻe ʻana i ke kaupaona kino.
ʻO kahi ʻōmole nui o ka lāʻau e hele pū me nā hōʻailona aʻe:
- Hoʻonui kaho.
- ʻO ka manaʻo mau o ka pōloli.
- Kamaʻilio me ka noʻonoʻo naʻau.
- ʻO ke ʻano o nā pilikia me ka hiamoe.
- Hypoglycemia.
E like me ke kōkua mua, pono ia e kau i ka mea maʻi i kahi honi liʻiliʻi, a laila e kāhea i kahi ambulance.
I nā kūlana paʻa, mālama ka poʻe loea lapaʻau i nā pae glucose a mālama i nā hana e hoʻopau ai i ka kūlana hypoglycemic.
I nā hihia hea i pāpā ʻia ai ka lāʻau lapaʻau?
ʻOiai he papa inoa inoa nui o nā hōʻino maikaʻi o ka lāʻau, pono ia e noʻonoʻo i nā ʻano like ʻole o nā mea ʻino e hiki mai ana ma hope o kona hoʻohana.
ʻO ka mea mua, pono e nānā pono i ka papa inoa o nā pāpā i ʻole i hiki ke hoʻokō ʻia ka mālama ʻana me ka hoʻohana ʻana iā Maninil
He ākea loa nā continications Maninil.
Ke loaʻa nei nā contraindications i kēia:
- ʻano hoʻōla maʻamau 1
- ma ka hihia o ka nānā ʻana i ka ketoocytosis maʻi maʻi a i ʻole ke ʻano o ka he makua ʻōiwi i loko o ka mea maʻi,
- ka hōʻike ʻana o ka haemogemia ma kahi maʻi,
- i ke alo o nā ala ākea
- hopohopo ʻia ka maʻi ʻōpio a ʻehā paha e ulu ai,
- inā he intolerance a hypersensitivity paha i hoʻokahi mea nui aʻe paha o nā lāʻau lapaʻau,
- leukopenia
- i ke kūlana ma hope o ka haʻalele ʻana o ka pancreatic,
- i ka heleʻana o ka lactose intolerance aiʻole lactase nele.
I kēia lā, ʻaʻole lawa ka ʻike e pili ana i ka hana a kēia lāʻau lapaʻau i ka mālama ʻana i ka maʻi diabetes i nā keiki. No laila ʻo ke kumu ke kuhikuhi ʻole nei i ka lāʻau no kēlā mau maʻi (a ʻoi aʻe he ʻumikumamāwalu mau makahiki). Eia kekahi, nā contraindications e lawe pū i ka lāʻau lapaʻau no nā kaikamahine hāpai a me nā wahine i ka wā o ka hoʻoulu ʻana.
Eia kekahi, me ka makaʻala nui, kuhikuhi ka lāʻau i kēia mau hihia:
- Inā he nui aʻe ka hopena o ka hypoglycemia,
- Inā loaʻa nā kumu e koi pono i ka hoʻololi o ka mea maʻi i ka hoʻomehana ʻana o ka insulin,
- Ma hope o ke kaʻina
ʻAʻole kahi e mālama i ka wā e hoʻopili ai iā Maninil, inā ua hōʻike ka mea maʻi i nā maʻi o ka pūnaehana ʻana.
Nā hōʻike o Maninil, nā loiloi e pili ana i ka lāʻau lapaʻau a me kona kumukūʻai
ʻO nā loiloi e pili ana iā Maninil i mea hoʻopaʻapaʻa. Aia nā manaʻo e hōʻike ana i ka lāʻau i ka hopena maikaʻi, ʻoiai ʻaʻole ka hōʻike ʻana i nā hopena ʻino. Hoʻomaopopo ka poʻe ʻē aʻe i ka loaʻa ʻole o ka hopena maikaʻi, a ma kahi hōʻike hōʻike maikaʻi ʻole, hoʻokoʻa ka momona wikiwiki. ʻAʻole pilikino ke kino o kēlā kanaka, no laila, inā ʻaʻole kūpono ka lāʻau lapaʻau no ka maʻi maʻi hoʻokahi, ʻaʻole ia he manaʻo ʻaʻole pono ka lāʻau lapaʻau.
I kēia lā, ʻo ke kumukūʻai o Maninil e pili ana i hoʻokahi haneli a me kanahā mau rubles. Hoʻokomo ʻia ka lāʻau lapaʻau i ka pūʻulu o nā lāʻau lapaʻau kālā. Loaʻa aia kekahi pono e hoʻohana i ka analogin Maninil a mea like paha.
He aha ka mea e hiki ai ke hoʻololi iā Maninil a ʻo wai ka mea i ʻoi aku ka maikaʻi ma waena o ka sulfonylureas?
Pono e hoʻomanaʻo ʻia nā mea ʻelua no ka lāʻau - Glibamide a me Glibenclamide. Loaʻa iā lākou i kā lākou hoʻonohonohoʻana ke ʻano lāʻau ikaika like me ka lāʻau lapaʻau Maninil. Wahi a ia, aia nā papa like i mau like a loaʻa nā hōʻailona like no ka hoʻohana. Kōkua i nā ʻōkuhi tableted ma lalo o ke kiʻekiʻe o ka glucose o ke koko a hāpai i ka hana ulu pancreatic insulin.
Pono e huli ʻia nā ʻano inoa o Maninil e ka inoa (inoa inoa), ʻo ia hoʻi, ʻo ia hoʻi.
He aha nā lāʻau lapaʻau maʻi ʻoluʻolu loa e haʻi i ka loea i ka wikiō ma kēia ʻatikala.
