Ua hoʻohana nui ʻia nā poʻe mai ka group biguanide i ka mālama ʻana i ka maʻi maʻamau ʻo 2. Eia nō naʻe, he nui nā hopena like o kēlā mau lāʻau. ʻO kēia ʻano mea pono ʻole ka metformin, no ka mea, ʻo ia ka mea nui i ke ʻano kumu o nā lāʻau lapaʻau?
I kēia mau lā, ʻike ʻia nā mea hou o kēia huahana a ke hoʻonui ʻia nei kona hoʻohana ʻana, me ka hoʻohana ʻana i ka lāʻau lapaʻau ʻaʻole wale nō i loko o ka maʻi paʻakikī o ka maʻi maʻi.
Hoʻohana lōʻihi ka lāʻau Metformin no ka mālamaʻana i ka diabetes mellitus type 2 i ka hele pū ʻana me kahi papa i kauoha ʻia e kekahi kauka. ʻAʻole hiki iā ia ke hoʻonāukiuki i ka pae o ka glucose i loko o ke koko, akā kōkua pū nō ia i ka hoʻemi ʻana i ke kaumaha nui, i mea nui no ka poʻe me kēia maʻi.
I kēia wā, ua ʻike pū ʻia nā hiʻohiʻona o ka lāʻau lapaʻau. Ua hoʻonohonoho ʻia i ka ʻepekema hiki i kahi kanaka ke lawe i ka Metformin e hoʻokō ai i kēia mau pahuhopu:
- Mālama ʻo ia i ka lolo mai ka wā kahiko, hiki iā ia ke hoʻohana ʻia no nā kumu prophylactic e kū kūʻē i ka maʻi o Alzheimer.
- Hoʻopilikia maikaʻi loa i ke kūlana o nā kīʻaha koko a me nā pili. No laila, me ke kōkua o Metformin, hiki ke hoʻomalu ʻia ka ulu ʻana o ka atherosclerosis vascular, ka hiki ʻole o ka puʻuwai, ka maʻi hypertension, ke ʻano o ka vascular.
- Hoʻemi i ka hopena o ka maʻi kanesa.
- Hoʻomaʻamaʻa pololei ka hoʻomaikaʻi ʻana i ka mākeke o nā kāne, kahi i hoʻokaʻawale ʻia ma ke ʻano o nā maʻi senile.
- Ka mea e pale ai i ka hoʻomohala ʻana o ka osteoporosis ma nā maʻi maʻi maʻi. Hoʻomaʻa pinepine pinepine ʻia nā wahine ma nā iwi palupalu ma hope o ka menopause, ʻoiai he nui ka hōʻemi o nā hormones - estrogen.
- Hoʻopilikia maikaʻi loa ia i ka hana o ke kulu thyroid.
- He hana pale i ka pili me ka pūnaehana hanu.
ʻOiai ka loaʻa ʻana o nā lāʻau lapaʻau he nui nā mea e pono ai, hiki ʻole ke haʻi pono e ola maikaʻi a hiki ke hoʻōla i nā maʻi he nui. E like me nā mea olakino ʻē aʻe, hiki ke hoʻohana ʻia ʻo Metformin e like me ke alakaʻi ʻia e ke kauka hele ʻana, me ka noʻonoʻo e hiki ke hōʻike ʻia o nā hopena āpau a me nā contraindications.
Pharmacological waiwai o ka lāʻau
ʻO ka Metformin kahi lāʻau lapaʻau ka papa ʻo biguanide i hoʻohana nui ʻia i ka mālama ʻana i ka maʻi maʻi type 2.
ʻO ka mea nui o ka lāʻau ka Metroformin hydrochloride, silicon dioxide, povidone, magnesium stearate, macrogol i hoʻohanaʻia e like me nā mea kōkua.
Hoʻohana nui ʻia ka lāʻau lapaʻau e hoʻohaʻahaʻa i ke kōhi koko. I ka manawa like, ʻo ka hoʻohaʻahaʻa ʻana i nā hōʻailona e loaʻa wale nō ma hope o ka kīʻaha nui, akā hiki nō iā ʻoe e hoʻohaʻahaʻa i ka pae haʻahaʻa. ʻO ka hana koʻikoʻi o nā papa i hiki iā ʻoe ke hoʻoponopono i ka hana o ka insulin e ka pancreas, he mea kūpono ia i ke kino a ʻaʻole e hoʻonāukiuki i ka hoʻomohala ʻana o ka hypoglycemia. Eia kekahi, ma waena o nā hopena maikaʻi e loaʻa i:
- ka hana kūlohelohe o nā hyperinsulinomy;
- ua hāʻawi ʻia i ka lilo kaumaha;
- ho'ēmi i ka hopena o ka hoʻomohala ʻana i nā maʻi o ka ʻōnaehana cardiovascular;
- hoʻopilikia maikaʻi i ka lipid metabolism i loko o ke kino;
- ho'ēmi i ke kaʻina o ka momona oxidation;
- hōʻemi i nā kiʻekiʻe kiʻekiʻe o ka cholesterol maikaʻi;
- hōʻemi i ka hopena o ka angiopathy maʻi maʻi;
- hōʻemi i ka triglycerides.
Lawe ʻia ka lāʻau ma ke ʻano, ma hope o ʻelua a ʻekolu mau hola e hoʻomaka ai ka hana kiʻekiʻe. Ma kahi o ʻeono mau hola ma hope o ka lawe ʻana i ka lāʻau, hōʻemi ka plasma o ke metformin, no ka mea ua pau ka make ʻana o ka mea hana.
Ma ke ʻano o ka mālama ʻana me kēia lāʻau lapaʻau ma hope o kekahi mau lā, hiki iā ʻoe ke nānā i kona hele ʻana i loko o ke koko me nā mea liʻiliʻi.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
Loaʻa ka lāʻau Metformin i ka puka papa ma nā ʻano like ʻole. Hiki ke kūʻai ʻia ka lāʻau lapaʻau ma nā māka laʻu o ke kūlanakauhale i nā palapala aʻe:
- 500 mg o ka hana ikaika i hoʻokahi papa;
- 850 mg o ka paipai ikaika;
- 1000 mg o ka metformin.
Mahalo i ka dosage, hilinaʻi nā kānāwai no ka lawe ʻana i ka lāʻau lapaʻau. Pono e hoʻolauna ʻia wale nō i ke kauka komo i hiki ke hāpai i ka hoʻohana ʻana i kēia lāʻau lapaʻau, ʻo ia hoʻi ma kahi ka pono o ka lāʻau lapaʻau i lawe ʻia ma mua. Ua kuhikuhi ʻia kahi papa no ka mālama ʻana i nā maʻi i hala mai ke kiʻi lāʻau maʻamau o ka maʻi a me nā ʻano pilikino o ke kino o ka mea maʻi. ʻO kahi kīʻaha nui āu e pono ai e hoʻolohe i ka wā e koho ai i kahi maʻa he nui o ka glucose i loko o ke koko a me ke ʻano kaumaha o ka mea maʻi.
ʻO ka hapa liʻiliʻi ma kahi e hoʻomaka ai ka mālama ʻana he 500 mg o ka lāʻau lapaʻau me kahi piʻi e hiki mai aʻe. Eia kekahi, ʻaʻole hiki i kahi lāʻau hoʻokahi ke ʻoi aku ma luna o ka mea i luna. No ka hoʻomau pono ʻia o ka lāʻau lapaʻau, e like me ke kō o nā papa i hoʻopaʻa ʻia, hiki ke hoʻokaʻawale ʻia ka nui o nā palapala i ʻelua a ʻekolu paha i ka lā. No laila, hiki ke pale aku i ka hoʻolālā ʻana o nā hopena maikaʻiʻole. Pono e oi aku ka nui o ka lāʻau lapaʻau ma luna o 3000 mg o ka mea ikaika.
I kekahi mau hihia, no ka laʻana, ka lawe ʻana i ka lāʻau lapaʻau no nā kumu prophylactic, pono e hōʻemi ʻia ka dosage e ʻelua i ʻekolu mau manawa.
Loaʻa ka hopena kiʻekiʻe loa o ka lawe ʻana i ka lāʻau lapaʻau ma hope o ka mālama mau ʻana o ʻelua pule.
Inā, no kekahi mau kūlana, nalowale kekahi lāʻau lapaʻau, ʻaʻohe mea pono e uku no ia me ka hoʻonui ʻana i kahi papaʻi.
Ke lawe nei i ka lāʻau lapaʻau, pono ia e noʻonoʻo i ka papa maʻamau o nā kaʻina metabolic a me ke olakino maikaʻi.
Pono e haʻi ʻia he nui ka lactic acidosis.
Nā hopena maikaʻi ʻole o ka lawe ʻana i ka lāʻau
ʻO ka Therapy a me ka mālama ʻana me Metformin e pono e hoʻokō ʻia ma lalo o ka mākaʻi lāʻau olakino. ʻAʻole hiki ke ʻoluʻolu a lawe i ka lāʻau lapaʻau ma nā ʻōpala iʻoi aku o nā ʻōlelo a ke kauka, a i ʻole hui pū ʻia me nā lāʻau ʻē aʻe i koho ʻia e ka mea maʻi.
Hiki i ka hoʻohana hewa ʻana o ka Metformin ke kumu i nā hopena ʻaoʻao he nui, e wehe ke ʻano maikaʻi o ka lāʻau no ka kino o ke kanaka.
ʻO nā hōʻike hōʻike kino nui o ka lāʻau lapaʻau e komo i kēia:
- nā pilikia pā o ka hana ʻana, ka mea e hele pū me ka utulula, nā ʻeha ma ka ʻōpū a i ʻole kahi maʻi ʻaʻa;
- kahi ʻano maikaʻi o ka metal ma ka waha e ʻike ʻia ma hope o kahi ʻaina.
- ninaki a me ka luaʻi
- nele i kekahi mau pūʻulu o nā waiora, no laila ka B12, no laila, ʻoi aku ia e komo i kahi komo o nā mea lapaʻau kūikawā, hiki iā ia ke hana i ke kiʻekiʻe o nā mea āpau i pono no ke kino.
- ka hōʻike ʻana o nā hopena kūloko i kekahi a i ʻole hapa o ka lāʻau lapaʻau;
- ke ʻano o ka hypoglycemia;
- ka hoʻomohala ʻana o ka acidact lactic;
- ʻO ka anemia megaloblastic i ka maʻi mellitus.
A inā hoʻokomo ʻo Metformin i ka pūʻulu o nā lāʻau palekana, pono ʻoe e heluhelu pono i nā mea i hōʻike ʻia ʻole maikaʻi ʻole. Pilikia paha ia o ka laau ina aole oe e hahai i na rula pono no kana oihana kalepa.
ʻO kekahi hopena maikaʻi loa mai ka hoʻohanaʻana i ka lāʻau lapaʻau ka lactic acidosis. Hoʻopili ʻia kēia maʻi me nā hōʻailona e like me ka lohi o ka hiamoe, mau ʻōpūʻeha, ka hoʻohaʻahaʻa i ke ʻano o ke kino a me ke koko, a me ka paʻakikī hoʻi ka hanu. Me ka hoʻouluʻana o kēlā maʻi like, koi ka mea maʻi i ka mālama maʻi.
ʻO ka acidact lactic kekahi o nā hopena ʻaoʻao e hele mai ma muli o ka hopena ikaika o ka lāʻau.
I nā hihia hea i pāpā ʻia ai ka lāʻau lapaʻau?
ʻO ka lāʻau Metformin ka inoa koʻikoʻi o nā contraindications i kona hoʻohana.
No laila, ma mua o ka hoʻomaka ʻana i kahi papa o ka mālama ʻana, pono ʻoe e heluhelu pono i nā ʻōkuhi. Inā aia kekahi mau hopena maikaʻi, e kamaʻilio me kāu kauka a kūkākūkā hou i nā hana e pili ana i ka lawe ʻana i ka lāʻau.
Lā ʻia ka hoʻohana ʻana i ka lāʻau lapaʻau i mua o nā mea i lalo a me nā maʻi.
- no ka mālamaʻana i ka maʻi diabetes mellitus type 1, nā mea maʻi maʻi-insulin;
- ka hoʻomohala ʻana o ka ketoacidosis, he coma a i ʻole ka kūpuna o kahi maʻi maʻi maʻi;
- nā hana koʻikoʻi koʻikoʻi i nā pūpū a me ka ate paha, a me ka manawa no ka nele o lākou;
- kekahi mau maʻi o ka ʻōpū hanu, a me ka pilikia no ka loaʻa ʻana o ka hanu;
- nā maʻi o ka ʻōnaehana cardiovascular, ka huhū puʻuwai a i ʻole ka myocardial infarction;
- ka hoʻomohala ʻana o ka maʻi i manaʻo ʻia e nā ʻano maʻi like ʻole;
- hana i kēia manawa a me nā hōʻeha;
- ma ka lā a ma hope o kekahi mau hoʻokolohua diagnostic, ua komo kēia i ka radiography a i ʻole nā radioisotropic diagnostics, ʻoiai ua hoʻohana ʻia kahi ʻāpana ʻokoʻa me ka iodine.
- lactic acidosis;
- intolerance a hypersensitivity paha i hoʻokahi a hapa iki o ka lāʻau lapaʻau;
- i ke alo o ka malō;
- ka hopena hoʻowahāwahā kino ʻole a hōʻino pinepine paha i ka waiʻona.
ʻO nā kaikamahine a me nā wahine hāpai i ka wā lactation ua pāpā ʻia ka lawe ʻana iā Metformin, me nā pilikia like ʻole me ka hoʻomohala maʻamau o ka pūpū. Me ke koi wikiwiki ʻana i ka lāʻau lapaʻau, pono e hōʻea i ka wahine ma ka umauma.
Eia kekahi, ʻo nā keiki ma lalo o ka ʻumikumamālima makahiki e pilikia nei.
Nā hōʻike o ka lāʻau Metformin
Hoʻomaopopo nā loiloi hoʻomanawanui i ka hopena maikaʻi e lawe mai ai ka hana Metformin. ʻO kona kumukūʻai kumukūʻai ma ka ʻāina o ka Lūkini Lūkini hiki mai i 170 a 260 rubles.
Inā pono, hiki i ke kauka hele ke hele aku e loli me kekahi huahana olakino me nā palapala like a me nā mea like like. I kēia manawa, hāʻawi ke kūʻai aku i ka lāʻau lapaʻau i nā mea kikoʻī o kēia mauʻano o ka lāʻau Metformin, e like me nā loiloi, he mau hopena maikaʻi nō hoʻi:
- Kūkulu - hoʻāʻo ʻia ke kōpū haʻahaʻa i loaʻa i nā ʻano like ʻole. ʻO ka mea hana nui ka metformin hydrochloride. Kōkua i ka hoʻoliʻiliʻi i ke kiʻekiʻe o ka glucose koko me ke kumu ʻole o ka hypoglycemia. ʻO ke kumukūʻai kumu o nā papa like, me ke ʻano he kānāwai, ʻaʻole iʻoi aku i ka 200 rubles.
- Bagometua - he lāʻau lapaʻau, aia i ʻelua mau mea hoʻoikaika i ka manawa hoʻokahi - metformin a me glibenclamide. ʻO kēia kahi hoʻomākaukau hoʻohui hoʻohui e hoʻohui i nā waiwai o nā kumulani ʻo biguanides a me nā derivatives sulfonylurea. Hoʻohana pinepine ʻia e mālama i nā maʻi diabetes mellitus type 2. ʻO ke kumukūʻai kiʻekiʻe o ka lāʻau lapaʻau he 210-240 rubles.
- ʻO Siofor kahi lāʻau lapaʻau mai ka pūʻulu biguanide, kahi kikowaena piha pono o nā papa Metformin. Hiki ke ʻano ke kumukūʻai o kona kumukūʻai ma loko o nā mākaʻai o ke kūlanakauhale mai ka 250 a 350 rubles.
- Sofamet - nā papa mai ka papa o ka dimethylbiguanides, kahi i loaʻa i nā ʻano like ʻole. Wahi a ka nui o nā hana ikaika, ua hoʻokumu ʻia ke kumukūʻai o ka lāʻau. E like me ke kānāwai, ke kumukūʻai o Sofamed i loko o nā lāʻau lapaʻau like ʻole o ke kūlanakauhale ʻaʻole iʻoi aku i nā rubles 130;
- Nova Met.
I kēia wā, ʻoi aku ka nui o nā meaʻikepili a me nā mea like nēnā paha. ʻO lākou āpau, ma ke ʻano he lula, he like ʻole a kūlike paha mau ʻokoʻa, akā ʻokoʻa i ka hui hana, ʻano, inoa. Eia kekahi, ʻoi aku ka loea o nā mea lapaʻau i ka hoʻohana ʻana o kēlā mau lāʻau lapaʻau e loaʻa ana, ma ka hoʻohui ʻana i ka mea hana maʻamau, ka hapa liʻiliʻi o nā mea kōkua.
Hāʻawi ʻia ka ʻike ma Metformin i ke wikiō ma kēia ʻatikala.
