ʻO ke kaumaha koʻikoʻi he pilikia honua ka mea i hoʻopā ai i Russia i kēia lā. ʻIke maopopo mākou i ka nui o kēlā me kēia pae o ka momona a pili i ke olakino: pili ia i ka hana o ka puʻuwai a me nā kīʻaha koko, e hoʻopau ana i nā hui a alakaʻi i ka hoʻomohala ʻana i ka maʻi maʻi.
ʻO kēia kumuhana koʻikoʻi ua hoʻolaʻa ʻia i ʻO kahi puke hou e kahi endocrinologist me 30 makahiki o kona mauʻike iā Olga Demicheva "Hormones, genes, mea momona." ʻO kahi ʻāpana mai ia mea, e pili ana i ka "make square" - a ua kapa ʻia hoʻi ʻo ia he metabolic syndrome, lawe mākou i kāu manaʻo.
Ma muli o ke koho kūlohelohe, lilo nā poʻe maʻamau i nā kūpuna a me ke ʻano lahilahi o ke ʻano kanaka o kēia wā, i hoʻokaʻawale ʻia e ko lākou mau hoa ʻohana e ko lākou hiki ke hōʻemi i ka momona i nā manawa pōkole o ka loaʻa ʻana o ka meaʻai a, no laila, e ola nei i nā manawa paʻa o ka noho ʻana o ka hapalua. E like me ka ʻōlelo, "ʻoiai ʻo ka momona momona, make nā mea make."
ʻO kēia mau kūpuna mamao loa no kā mākou, hiki ke mālama i ka momona, nāna i hāʻawi i nā hua ola pono, ka mea i hoʻohui i kēia kaha e hōʻiliʻili i ka momona ma ka pae genetic. Pehea i maopopo ai kēia ʻike?
ʻO ka mea ʻoi no ka wikiwiki wikiwiki o ka hōʻiliʻili ʻana o ka iwi adipose a me kona mālama (penapena), nui ka nui o ka insulin. ʻO ia kahi o ka hōʻiliʻili o ka nui o nā momona i pili me ka hyperinsulinism. Akā, ke mālama nei i ka hiki ke mālama i ka momona me ka ikaika, pono e pale ke kino iā ia iho i ka hōʻemi ʻana o ka nui o ke kōpaʻa koko ma ke ʻano o ka hyperinsulinism mua. Ma hope o nā mea a pau, ʻo ka lua o ka hana nui o ka insulin ke hoʻohaʻahaʻa ʻana i ke kō koko koko ma o ka hoʻokaʻa ʻana i nā ʻona no ka hoʻomohala hana. A eia kekahi mau kūpuna i loaʻa ka genetic mutation e hoʻolako ai i kahi hana palekana i kapa ʻia, i kapa ʻia "ka pale ʻana i ka insulin". ʻO ka paleʻana i ka insulin he emi i ka paʻakikī o nā sela o ke kino i ka hopena o ke kōmike.
ʻO ka poʻe me ka "genotype ekonom", ʻoi aku i ka hoʻololi ʻia ʻana o nā kūlana kūlohelohe, pili i ka laha ʻana o kēia mau gen i ka heluna. ʻO ka Hyperinsulinism, nāna i kōkua i ko mākou poʻe kūpuna e hōʻiliʻili i nā mālama momona i loko o nā manawa pōkole o ka hoʻopua nui ʻana, ʻaʻole i hana ʻino, no ka mea ua nalo ke lōʻihi no ka nui o ka ʻai. I nā wā pōloli, ua noho ka poʻe o ka poʻe mua ma mua o nā nīnū momona i hōʻiliʻili ʻia. ʻAʻole paʻa a lākou hyperinsulinism. ʻO mākou, ko lākou mau mamo mamao loa, ʻaʻohe manawa o ka wikiwiki i hoʻolōʻihi ʻia, akā hiki iā mākou ke hōʻuluʻulu i ka momona i hoʻoili ʻia mai nā kūpuna: he kūlia ka insulin a me ka hyperinsulinism.
ʻO nā hyperinsulinism kūpaʻa a me ka paleʻana i ka insulin he mau loulou i ka mea e kapa ʻia nei "he metabolic shifts" alakaʻi i ka obesity, atherosclerosis, hypertension a me diabetes mellitus. Eia kekahi makana momona maikaʻi a mākou i loaʻa mai ko mākou mau kūpuna, i koi ʻia e ola i mua o nā pilikia maʻamau me ka meaʻai.
ʻIke paha ʻoe i ka mea ʻo ka endocrine nui loa i loko o kahi mea obese i kapa ʻia? Adipose kiko!
Heʻoiaʻiʻo kēia: ka nui, "ʻeha" momona i ka hana endocrine nui. I ka makahiki 1988, ua ʻōlelo mua mai ke Kauka G. Reaven, he mea kū i ka insulin, e hoʻoulu ai i ka hyperinsulinism compensatory, ka mea e hoʻokūkū ai i ka metabola cascade: huʻihuʻi, nā kākāwa a me ka metabolidity lipid, a me ka holomua o ka pathov cardiovascular.
ʻO ka wikiwiki wikiwiki o ka momona a me ka maʻi diabetes type 2 e kōkua i ka "maʻi" maʻi o ka atherosclerosis a me ka hypertension arterial, e hoʻonui ana i ka maʻi cardiovascular. ʻAʻole ia he mea paʻa o kēia "kit" - obesity, diabetes mellitus, hypertension arterial a atherosclerosis - i ka hopena o 80s o ke kenekulia i hala aku nei, me ka lima lima o ka Propesor N. Kaplan, i kapa ʻia ʻo "quartet make". I nā makahiki 90, ua noi ʻia nā ʻōlelo aʻo M. Henefeld a me W. Leonhardt i ka huaʻōlelo ʻo "metabolic syndrome", kahi mea i hoʻohana nui ʻia e nā kauka.
Ua kau ʻo Profesor M. R. Stern i ka makahiki 1995 i kahi hypothesis e pili ana i ka "kumu maʻamau" o ka atherosclerosis a me ka maʻi diabetes mellitus - kūʻē i ka insulin. I kēia lā ʻike maopopo mākou i ka poʻe me nā maʻi prediabetic o ka hōʻoki kino ka hoʻoliʻiweʻe (ua wehewehe ʻia kēia mau maʻi ma ka puke ma ka puke "Diabetes" mai nā papa ʻōlelo "Kauka Rodionov Academy"), ʻo nā kaʻina o ka atherosclerosis ka wikiwiki i ʻoi aku ka wikiwiki ma mua o ka poʻe me ka metabolism hoʻoneʻe haʻahaʻa.
Ma ke kaulike, pono e hoʻomaopopo ʻia i ka makahiki 1948, ua kākau ʻo ke kauka kaulana kaulana ʻo E. M. Tareev: "ʻO ka manaʻo o ke ʻano hypertension e pili pinepine ana i ka hypersthenic obese me ka hiki ʻana o ka hōʻemi a me ka metabolism, me ke kōkō ʻana o ke koko e nā huahana o ka metamorphosis piha - kolesterol, aila waikiki ..." . ^ E Ha yM. No laila, ʻoi aku ma mua o 70 mau makahiki i hala aku nei, ua hoʻopiʻi kā mākou compatriot maikaʻi i ka manaʻo o ka metabolic syndrome.
Hoʻomaka ka hanana ākea o ka metabolic syndrome i ke ʻano o kahi maʻi i kekahi mau ʻāina, ʻo ia hoʻi ʻo Russia, a hiki i ka 25-35% ma waena o ka poʻe pākeke.
I kēia manawa i ka Pūnaewele Pūnaewele Rūkai hiki iā ʻoe ke loaʻa ma mua o 100 tausani mau loulou i nā hoʻopuka e pili ana i kēia pilikia. No laila, i ka honua hou, ma muli o ka ʻai ʻana i ka ʻai me ka hōʻemi ʻole ʻana i ka ikehu a me nā kūlana o ka hyperinsulinism, hoʻonaninani ʻia ke ʻano momona o ka momona no ka hoʻoiho ʻana. Ke hoʻomaopopo nei i nā pilikia o ka momona o ke kanaka, ʻo WHO a me ka UN ke kū nei i nā papahana no nā ʻāina āpau e hakakā i nā "maʻi ʻole e hui ai." Lawe mai i kekahi mau hopena.
I nā ʻāina e hoʻokō nei i nā papahana kūpono no ka pale ʻana i nā maʻi like ʻole, ka mea e pili ana i ka momona, diabetes mellitus, ka maʻi kanesa a me nā maʻi cardiovascular, ua loaʻa ka hanana o ka hōʻeha ʻana i nā puʻuwai a me nā hōʻeha mai ka wā o ka kenekulia 21. Ua ʻike ka poʻe noho o nā ʻāina he nui i ka pōʻino o ka uahi kino, ka hana kūlohelohe, inu nui ʻana i ka waiʻona wai a ua hoʻoholo iā lākou iho e hoʻololi i ko lākou ʻano. Akā ke noho mau nei nā ʻāina he nui ma ka honua, e komo pū ana me Rūsia, kahi i hoʻemi ʻia ai ka make ma mua o nā maʻi cardiovascular. ʻO ke kumu o kēia ka "quartet make," ʻo ia hoʻi, ʻo ka metabolic syndrome.
Pehea e hoʻoholo ai inā loaʻa ʻoe i nā hōʻailona o ka metabolic syndrome? No ka hana ʻana i kēia, e ana i ka ʻōpū o ka ʻāʻī, e ana i ke kahe o ke koko, hana i ka hōʻike koko biochemical no ka nui kolamu, HDL, LDL, triglycerides, glucose a me ka hemoglobin glycated. E hiki i nā hopena ke hoʻomaopopo i ke kau ʻana inā loaʻa kekahi hapa o ka "quartet make". A i ʻole like ʻaʻole paha? E nānā iā ia.
Ke mua he hoʻonui kēia o ka ʻūhā pale: i nā wahine - ʻoi aku ma mua o 80 cm, i nā kāne - ʻoi aku ma mua o 94 cm (ʻōpū o ka ʻōpū).
Kahua ka hanalena o ka momona metabolism me ka piʻi o ke kahe o ke koko o ka triglycerides a me ka cholesterol a me nā lipoproteins haʻahaʻa haʻahaʻa (LDL), me kahi hoʻohaʻahaʻa nui me ka lipoprotein kūloko kiʻekiʻe (HDL).
Ekolu ka hoʻonui ʻana i ke koko (BP).
Eha lā, ʻehā metabolism glucose mea i nele, mai ka pre-diabetes i ka hoʻokeo wikiwiki i ka wikiwiki (NGN) a me ka hoʻohaʻahaʻa glucose glucose (NTG) i ka hoʻomohala ʻana o ke ʻano type mabetitus type 2.
ʻO ka mea pōpilikia i nā huaʻōlelo o ka hopena o ka maʻi cardiovascular ka maʻi ʻeha o ka ʻōpū (a visceral) paha. ʻO ka hoʻonāʻana i kahi'ōpū o ka pehu o ka pūpū o ka momona ma ka ʻōpū a me nā pūhaka.
Hiki ke kapa ʻia nā ʻōkuhi Visceral i ka violin mua o ka "quartet make." A, ʻo ka mea kaumaha, he ʻano ākea loa kēia: ma Rūsia, ʻoi aku ka hapalua o nā poʻe noho ma mua o 40 mau makahiki e ʻoi aku ke kaumaha, e huli ana i ka momona o 50 mau makahiki. I ka nui o nā manawa, aia ma visesal obesity.
Hiki iā mākou ke ʻōlelo he centimeter tape kēia, ʻaʻole ia ka pauahi, ʻo ia ka mea hana nui e hoʻokumu ai i ka maʻi o ka "ʻōpū o ka ʻōpū."
ʻO kekahi manawa i ka nui o ka nui o ka pelu o ka nui, ma mua o nā kāne e hana i ke ʻano haʻuki ikaika, hiki ke alakaʻi i ka hoʻonui ʻana i BMI, akā, e hōʻike pololei ka ʻōpū i ka hōʻoki ʻana a i ʻole ka loaʻa ʻana o ka momona momona i loko o ka ʻōpū a me nā pūhaka. ʻO ka mahalo, ʻo kēia kuhikuhi i nā pākeke ʻaʻole hilinaʻi i ka ulu ʻana, i ka hoʻohālikelike ʻia me BMI.
ʻO ka hapa nui o nā poʻe noiʻi e manaʻo nei ʻo ka obesity ka mīkini ka pahū o ka "quartet make". Akā ʻo ka mea luhi o ka metabolic syndrome ka mea i loaʻa i kekahi o nā lālā o ka Quartet ke kumu nui, hoʻonui ʻia i kēlā me kēia o ke koena o ke koena. ʻO kā mākou predisposition genetic i ka pale ʻana i ka insulin, ʻaʻole ia he predisposition pololei loa i ka momona inā hoʻokomo ʻoe i kahi ola olakino.
