ʻO ka lāʻau lapaʻau no nā maʻi maʻi Glimepiride: i nā ʻōlelo aʻoaʻo a me nā loiloi hoʻomanawanui

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ʻO Glimepiride (Glimepiride) - nā kūlana hou o ka hoʻomākaukau ʻana o ka sulfonylurea. Me ka maʻi o ka maʻi diabetes, e hoʻonui ana i ka hoʻokuʻu o ka insulin i loko o ke koko, e hōʻemi ana i ka glycemia. No ka mea mua, ua hoʻohana ʻia kēia ʻano hana e Sanofi i mau papa ʻo Amaryl. Ke hana ʻia nei nā lāʻau lapaʻau me kēia ʻano hana a puni ka honua.

Hoʻomaʻi maikaʻi ʻia ka glimepiride Lūkini, me ka hoʻohaʻahaʻa maikaʻi i ke kō, e hōʻemi i ka hopena o nā ʻaoʻao, e like me nā papa mua. Hōʻike nā hōʻike i ka maikaʻi loa a me ka uku haʻahaʻa o nā lāʻau lapaʻau home, no laila ʻaʻole ia he mea kupanaha no ka makemake pinepine o ka maʻi maʻi maʻi Glimepiride i ka Amaril kumu.

ʻO wai e hōʻike ʻia ana he glimepiride

Hoʻokomo ʻia ka lāʻau lapaʻau no ka hana maʻamau o ka glycemia wale nō i ka maʻi maʻi type 2. ʻAʻole ia e kuhikuhi i ka ʻōlelo aʻo i ka wā e hoʻāpono ʻia ka mālama ʻana me Glimepiride, ʻoiai ke koho ʻana i kahi lāʻau lapaʻau kūikawā a ʻo kāna mea nui ka paʻakikī o ke kauka. E hoʻāʻo mākou e nānā i ka mea e hōʻike ʻia nei i ka lāʻau Glimepiride.

Haka ka Sugar i ka maʻi diabetes no nā kumu ʻelua: no ka pale ʻana i ka insulin a me ka hoʻokaʻawale ʻana i ka hoʻokuʻu ʻana i ka insulin mai nā beta beta i loaʻa i ka pancreas. Ka hoʻomohala ʻia ke kūlohelohe insulin ma mua o ka puka ʻana o ka maʻi diabetes, ʻike ʻia i nā mea maʻi me ka momona a me nā prediabetes. ʻO ke kumu ke ʻai maikaʻi ʻole ʻana, nele i ka hoʻomaʻamaʻa, keu. Hoʻopili ʻia kēia ʻano me ka hoʻonui ʻana i ka insulin, ma kēia ʻano e hoʻāʻo ai ke kino e pale i ka pale ʻana o nā maʻi a hoʻomaʻemaʻe i ke koko o ka momona glucose. I kēia manawa, ʻo ka hoʻololiʻana i ke ʻano o ka hoʻololi ʻana i ke ola olakino a kuhikuhi i nā metformin, kahi lāʻau lapaʻau e hoʻōla maoli ana i ka pale ʻana i ka insulin.

ʻO ke kiʻekiʻe nui o ka glycemia o ka mea maʻi, ʻoi ka nui o ka hoʻomau ʻia o ka maʻi mellitus. Hoʻopili ʻia nā maʻi ʻoi a me ka hoʻohaʻahaʻa i ka huna ʻana i ka insulin, a hele hou ka hyperglycemia i ka mea maʻi. Wahi a nā kauka, i ka hopena o ka maʻi maʻi, ua loaʻa ka hemahema i ka ʻina o ka hapalua o nā maʻi. Ma kēia hoʻi i ka maʻi, i ka hoʻohui ʻana i ka insulin, nā lāʻau lapaʻau e hoʻoikaika ana i ka hana ʻana o nā hua beta e pono ke kuhikuhi. ʻO ka mea e ʻoi loa a me ka hopena o lākou he derivatives o ka olonylurea, pōkole PSM.

ʻO ka maʻi maʻi a me nā hoʻohaʻahaʻa manaʻo e hana ia i ka wā ma mua

  • Ka hana maʻamau o ke kō -95%
  • Hoʻokuʻuina o ka pua thrombosis - 70%
  • Hoʻopau i kahi puʻuwai ikaika -90%
  • Hoʻopau i ke kiʻekiʻe o ke koko - 92%
  • ʻO ka hoʻonuiʻana i ka ikehu i ka wā, hoʻomaikaʻi i ka hiamoe i ka pō -97%
Hoʻohālikelike Kahumoku
Arkady Alexandrovich
Endocrinologist me kaʻike
E nīnau i ka mea loea
ʻO Glimepiride ka lāʻau lapaʻau hou loa a palekana i ka hui PSM. No nā hanauna hou a ua kauoha ʻia no ka hoʻohana ʻana e nā hui endocrinological a puni ka honua.

Wahi a nā mea i hōʻike ʻia i mua, e hōʻike mākou i nā hōʻailona no ka koho ʻana i ka lāʻau Glimepiride.

  1. ʻO ka nele o ka hana pono o ka meaʻai, ka hoʻomaʻamaʻa a me ka metformin.
  2. ʻIke ʻia e ka nānā ʻana i ka nele o kā lākou iho ponoʻī.

Hiki i ke ʻikepili ke hoʻohana i ka hoʻohana ʻana i ka lāʻau Glimepiride me ka insulin a me ka metformin. Wahi a nā loiloi, hele maikaʻi ka lāʻau me nā glitazones, gliptins, incretin mimetics, acarbose.

Ke ʻano o ka hana o ka lāʻau

ʻO ka hoʻokuʻu ʻana o ka insulin mai ka pancreas i ke kahe koko e hiki ke kūpono ma muli o nā kahui KATP kūikawā. Aia lākou ma kēlā me kēia kelepona ola a hoʻolako i ka kahe o ka pāhana ma o kona membrane. Ke paʻa ka hoʻāʻo ʻana o ka glucose i nā moku i loko o nā palena maʻamau, e wehe ʻia kēia mau kahawai ma nā cell beta. Me ka uluʻana o ka glycemia, pili lākou, kahi e hoʻoiho ai i ka calcium, a laila hoʻokuʻu i ka insulin.

ʻO ka lāʻau Glimepiride a me nā mea āpau PSM e pani hou loa, e hoʻonui ai i ka hana o ka insulin a me ka huna. ʻO ka nui o ka hāmeʻe i hoʻokuʻu ʻia i loko o ke koko wale nō e kau i ka dosage o glimepiride, a ʻaʻole ma ka pae o glucose.

I nā makahiki i hala iho nei, ua hānai ʻia a ua hoʻāʻo ʻia ka 3 mau hanauna, a he ʻano hou. ʻO ka hana o nā lāʻau lapaʻau mua, ka chlorpropamide a me ka tolbutamide, i kaha nui ʻia e nā lāʻau maʻi maʻi maʻamau, ka mea e alakaʻi pinepine ai i ka hypoglycemia koʻikoʻi. Me ka hiki ʻana o ka hanauna PSM 2, glibenclamide, glyclazide a me glipizide, ua pane ʻia kēia pilikia. Pili lākou i nā mea ʻē aʻe he mauwaliwali loa ma mua o ka PSM mua. Akā, loaʻa i kēia mau lāʻau i nā pōkole: i ka hoʻopiʻi ʻana i ka meaʻai a me nā ukana, hoʻoulu lākou i ka hypoglycemia, alakaʻi i ka loaʻa ʻana o ka paona lohi, a no laila, he nui o ka pale ʻana i ka insulin. Wahi a kekahi mau noiʻi, hiki i nā hanauna PSM 2 ke hoʻopōʻino i ka hana naʻau.

I ka wā e hoʻokumu ai i ka lāʻau lapaʻau Glimepiride, ua lawe ʻia nā hopena o luna. Ua mālama lākou i ka hōʻemi iā lākou i ka hoʻomākaukau hou.

Loaʻa o Glimepiride ma luna o PSM o nā hanauna i hala.

  1. ʻO ka hopena o ka hypoglycemia i ka wā i lawe ʻia ai ka haʻahaʻa. Ua emi iki ka pilina o ka lāʻau me nā receptors ma mua o kāna hui hui hui, ʻoi aku, ʻo ke kino kekahi i mālama i nā hana pono e pale ai i ke kūmole o ka insulin me ka haʻahaʻa haʻahaʻa. Ke pāʻani nei i nā haʻuki, ʻaʻole hemahema o nā kīleʻaleʻa i ka meaʻai, nā glimepiride e hōʻeha i ka hypoglycemia haʻahaʻa ma mua o PSM. Hōʻike nā nānā i ke kō i ka wā e lawe ai i nā papa glimepiride e hāʻule ma lalo o ka maʻamau i ka 0.3% o nā maʻi maʻi.
  2. ʻAʻohe hopena ma ke kaupaona. ʻO ka nui o ka insulin i loko o ke koko e pale i ka wāwahi i ka momona, ʻo ka hypoglycemia pinepine e hāʻawi i ka nui o ka makemake a me ka hoʻokomo o ka caloric intake. ʻO Glimepiride ka palekana ma kēia hana. Wahi a nā mea maʻi, ʻaʻole ia e hoʻokau i ka paona, a me ka momona ʻo ia e hāʻawi pū i ka hoʻolilo ʻana.
  3. ʻO ka haʻahaʻa haʻahaʻa o nā maʻi cardiovascular. Hiki i ka PSM ke hoʻopili me nā kahawai KATP i loaʻa wale i ka pancreas, akā i nā paia o nā kīʻaha koko, e hoʻonui ana i ka hōʻeha o kā lākou pathology. Hana wale ka glimepiride lāʻau i ka pancreas, no laila e ʻae ʻia no ka poʻe maʻi maʻi me ka angiopathy a me ka maʻi puʻuwai.
  4. Hōʻike nā ʻōkuhi i ka hiki o Glimepiride e hōʻemi i ka pale ʻana i ka insulin, hoʻonui i ka synthesis glycogen, a me ka pale ʻana i ka hana glucose. ʻOi aku ka hana o ka haʻahaʻa ma mua o ka metformin, akā ʻoi aku ka maikaʻi ma mua o ke koena o PSM.
  5. Ke hana wikiwiki nei ka lāʻau lapaʻau ma mua o nā mea analogue, ke koho ʻana i kahi hapa a me ka loaʻa ʻana o ka uku no ka maʻi diabetes no ka liʻiliʻi.
  6. Hoʻopuka nā papa Glimepiride i nā lua o ka sela o ka insulin, no laila, hōʻemi lākou i ka glycemia wikiwiki ma hope o ka ʻai ʻana. Hana nā lāʻau kahiko i ka mahele 2.

ʻĀnō

ʻO ka dosage maʻamau o ka glimepiride, nā mea hana i hoʻoponopono, ʻo ia ka 1, 2, 3, 4 mg o ka waiwai ikaika i kahi papa. Hiki iā ʻoe ke koho i ka helu kūpono o ka lāʻau lapaʻau me ka helu kūpono, inā pono, e maʻalahi nā loli a hoʻololi ʻia. Ma ke kānāwai, ua paʻa ka papa i ka pilikia, e hiki ai iā ʻoe ke hoʻokaʻawale iā ia i ka hapalua.

Hoʻonui ka hopena o ke kōpaʻa ʻana i ke kō me ka hoʻonui ʻana i ka pākaukau mai ka 1 a i ka 8 mg. Wahi a nā maʻi maʻi, nui ka poʻe e pono ai ka 4 mg a i ʻole ka liʻiliʻi o ka glimepiride e uku no ka maʻi maʻi. Hiki i nā dosages nui i nā maʻi me ka decompensated diabetes a me kahi kūʻē o ka insulin. Pono lākou e hoʻohaʻahaʻa i ka wā e hoʻokau ke aupuni - e hoʻomaikaʻi i ka naʻau o ka insulin, e emi ana ke kaumaha, a me ke ʻano o ke ʻano o ke ʻano.

ʻO ka make i manaʻo ʻia i loko o ka maʻi glycemia (ka hoʻohālikelike hoʻohālikelike e like me ke aʻo ʻana):

Dosis mgHoʻemi ka hana
Hoʻolaha kūmole, mmol / lHoʻopau i ka kūpaʻa postprandial, mmol / lHologlobin glycated,%
12,43,51,2
43,85,11,8
84,15,01,9

ʻO ka ʻike mai nā ʻōlelo ʻōlelo i ka kaina e koho ai i ka pākaukau i makemake ʻia:

  1. ʻO ka dosage hoʻomaka e 1 mg. ʻO ka maʻa iki i nā maʻi maʻi me ka hoʻohaʻahaʻa haʻahaʻa ʻia, a me nā poʻe maʻi me ka hiki ʻole o ka renal. ʻAʻole pili ka maʻi o ka naʻau i ka nui o ka nui.
  2. Hoʻonui ʻia ka nui o nā papa a hiki i ka loaʻa ʻana o nā mea makemake gula. I mea e pale ʻole ai i ka hypoglycemia, hoʻonui pinepine ʻia ka nui, ma nā manawa o 2 mau pule. I kēia manawa, pono nā ana o ka nui o ka glycemia ma mua o ka maʻamau.
  3. Keʻano ulu lāʻau: a hiki i 4 mg, e hoʻohui 1 mg, ma hope - 2 mg. Ke hele i ka glucose i ka maʻamau, a kāpae i ka hoʻonui ʻana i ka nui o nā papa.
  4. ʻO ka dosis ʻokoʻa loa ka ʻelee loa he 8 mg, ua mahele ʻia i nā ʻāpana he: 2 a me 4 mg paha; 3 a me 2 mg.

Nā ʻōlelo kikoʻī no ka hoʻohana

ʻO ka hopena kiʻekiʻe o ka lāʻau lapaʻau e hiki mai ana ma kahi o 2 mau hola mai kona hoʻoponopono. I kēia manawa, emi iki ka glycemia. Ka mea, inā inu ʻoe iā Glimepiride hoʻokahi manawa i ka lā, e lilo kēlā huakaʻi nui, inā ʻoe e hoʻokaʻawale i ka ʻawa ma 2 mau manawa, e lilo ana ka hopena, akā he ʻoluʻolu. Hoʻomaopopo i kēia hiʻohiʻona o ka lāʻau lapaʻau, hiki iā ʻoe ke koho i ka manawa o ka hoʻokomo. Manaʻo ia e hāʻule ka papa kiʻekiʻe o ka hana ma ka manawa ma hope o ka manawa piha o ka ʻai ʻana me nā kalapona, a ʻaʻole kū pū me ka hana pilikino i hoʻolālā ʻia.

Hoʻopili ʻia ka hopena o ka hypoglycemia e kaʻai ʻole a i ʻole ka hōʻemi kino ʻana, nā hana kiʻekiʻe me ka naʻau ʻole i ka nui o ka paʻakai, nā maʻi ʻeha, nā hopena endocrine, a me kekahi mau lāʻau lapaʻau.

Hoʻopau ka lāʻau lapaʻau e like me ke kuhikuhi ʻana:

Ka kuhikuhi ʻana o ka hanaKa papa inoa o nā lāʻau
Hoʻonui i ka hopena o nā papa, hoʻonui i ka hōʻeha o ka hypoglycemia.ʻO ka insulin, nā hui antidiabetic papa. Steroids, testosterone, kekahi antibiotics (chloramphenicol, tetracycline), streptocide, fluoxetine. Antitumor, antiarrhythmic, antihypertensive, antifungal agents, fibrates, anticoagulants.
E hoʻonāwaliwali i ka hopena o ke kōpoki, ke hoʻonui iki ʻana i ka hoʻoleʻa o ka lāʻau lapaʻau Glimepiride pono.Diuretics, glucocorticoids, adrenomimetics, estrogens, triiodothyronine, thyroxine. ʻO nā dosis nui o ka waiū B3, mālama lōʻihi a me nā laxatives.
Hoʻonui kēia i nā hōʻailona o ka hypoglycemia, kahi mea paʻakikī iā ia i ka ʻike.Clonidine, sympatholytics (reserpine, octadine).

Palapala hoʻohālikelike o ka alkoholie mai nā kuhikuhi glimepiride: hiki i nā mea inu ʻona ke hoʻonui i ka hopena o ka hopena o ka lāʻau lapaʻau, hiki ʻole i ka mea nānā ke kō i ke kō koko. Wahi a nā loiloi, e kū pinepine ka glucose i ka wā pāʻina, akā ia po ke hāʻule nui nei, a hiki i ka hypoglycemia koʻikoʻi. Hoʻopau ikaika ka inu ʻana i ka uku no ka maʻi diabetes, ʻaʻohe mea e kau ʻia ai ka mālama ʻana.

Nā hiʻohiʻona o ka lawe ʻana i nā keiki a me nā wahine hāpai

I ka wā e hoʻohana ai i ka wā hāpai, komo ka lāʻau Glimepiride i ke koko o ka wahine hāpai a hiki i ka hypoglycemia ma loko. Eia hoʻi, hoʻokomo ka waiwai i ka waiū umauma, a mai laila i loko o ka digestive tract o ke pēpē. I ka wā hapai a me HB, lawe pio iā Glimepiride. Hoʻololi ka FDA (American Medicines Authority) iā Glimepiride i kahi papa C. ʻO kēia ke ʻano o nā noiʻi holoholona i hōʻike ʻia he hopena maikaʻi ʻole o ka pūpū.

ʻAʻole i kuhikuhi ʻia ʻo Glimepiride no nā keiki, ʻoiai inā lākou e hōʻike ana me ka maʻi maʻamau o ka 2. ʻAʻole i hōʻike ʻia ka lāʻau lapaʻau i nā hoʻokolohua e pono ai, ʻaʻole i aʻo ʻia ka hopena i ka mea ulu nui.

Kahi papa inoa o nā hopena ʻaoʻao

ʻO ka hopena koʻikoʻi nuiʻole o Glimepiride he hypoglycemia. Wahi a nā hoʻokolohua, ʻoi loa ka hoʻoweliweli ʻia o kona pilikia ma mua o ka mana o PSM ikaika - glibenclamide. Holo i ka Sugar, ka mea i alakaʻi ai i ka hoʻokipa a me nā poʻe e hoʻokaʻawale i nā glucose, i loko o nā mea maʻi ma Glimepiride - 0.86 ʻāpana ma kahi o 1000 mau makahiki. Hoʻohālikelike me ka glibenclamide, kēia ʻōkuhi he 6.5 mau manawa haʻahaʻa. ʻO ka pane kūponoʻole o ka lāʻau, ʻo ia ka hoʻohaʻahaʻa haʻahaʻa o ka hypoglycemia i ka wā o ka hana hoʻoikaika a hoʻolōʻihi.

ʻO nā hopena koʻikoʻi koʻikoʻi o ka glimepiride mai nā kuhikuhi no ka hoʻohana ʻana:

Kahi ʻāina kue ʻoleʻO keʻanoAuawaea
ʻŌnaehana ʻōnaehanaAllergic hopena pili. Hiki mai ma o ka glimepiride wale nō, akā ma nā mea ʻē aʻe o ka lāʻau lapaʻau. I kēia hihia, ke hoʻololi nei i ka lāʻau lapaʻau me ka mea hoʻohana o kekahi mea hana hou e kōkua paha. ʻO nā maʻi kūlohelohe e koi ana i ka haʻalele koke o ka lāʻau e laha loa.< 0,1%
ʻŌpala GastrointestinalHe kaumaha, naʻau o ka piha piha, ʻeha o ka ʻōpū. Nā maʻi ʻeha, maʻi ʻoluʻolu.< 0,1%
KokoHoʻoholo i ka helu platelet. Aia kahi hōʻike no kahi hihia kaʻawale o thrombocytopenia koʻikoʻi.< 0,1%
ʻO ka hōʻemi ʻana i ka nui o nā sela keʻokeʻo keʻokeʻo, nā ʻāpana koko ʻulaʻula. Hyponatremia.nā hihia kūikawā
PāʻāluaHoʻonui ka nui o nā enzyme hepatic i ke koko, hepatitis. Hiki i nā ala āpau ke kūkulu i ka palaualelo, no laila koi ko lākou hiʻohiʻona e hoʻokuʻu i ka lāʻau. Ma hope o ke hoʻopauʻana, e nalowale nā ​​neʻeʻana.nā hihia kūikawā
ʻIliPhotosensitivity - kahi mālamalama i ka ʻike pono i ka lā.nā hihia kūikawā
Nā Organs o ka hihiʻoI ka hoʻomaka ʻana o ka hoʻōla a me ka piʻi ʻana o ka maʻa, hiki ke hiki ke hele i ka ʻike maka transientment. Hoʻopili ʻia lākou e ke kaona nui o ke kō a e hoʻomake ma kā lākou pono iho i ka wā e hoʻohālikelike ai nā maka i nā kūlana hou.ʻaʻole i wehewehe ʻia

Aia kekahi leka e pili ana i ka hiki ke hūnā ʻia o ka hormone antidiuretic. Ke hoʻāʻo ʻia nei kēia ʻaoʻao kūpono, no laila ʻaʻole i komo pū i nā ʻōlelo aʻoaʻo.

Hiki i kahi overdose

ʻAʻole ʻano he aanaha a maʻalahi ke kaila ʻo Glimepiride, ke waiho mau nei ia i kahi derivative sulfonylurea, ʻo ia ke ʻano he overdose kona hopena i ka hypoglycemia. Loaʻa kēia hopena ʻaoʻao i ka ʻoihana o ka lāʻau lapaʻau, hiki ke pale wale i ka nānā pono ʻana i ka pauʻa.

ʻO ka rula no ka pale ʻana o ka hypoglycemia mai nā ʻōlelo i hoʻohana ʻia: inā i ʻike ʻia ka papa ʻaila Glimepiride, a ʻaʻohe hoʻi i maopopo i ka inu ʻana i ka lāʻau, ʻaʻole e hoʻonui ʻia ka ʻai ma ka hopena aʻe, inā paha ua kū mai ke kō koko.

Hiki ke hoʻopau i ka hypoglycemia me ka glucose - wai momona, kaʻaila a me ke kō. ʻAʻole pono e kali no nā hiʻohiʻona hiʻohiʻona, lawa nā glycemic data. ʻOiai ka hana ʻana i ka lāʻau lapaʻau i kahi kokoke i hoʻokahi lā, hiki i ke kō ke hoʻōla i ka maʻamau ke hoʻomau mau i nā helu i nā pōʻino. I kēia manawa āpau pono ʻoe e nānā i ka glycemia, mai haʻalele i ka maʻi maʻi maʻi wale.

Ka manawa paʻa nui o ka wā nui, ka lōʻihi o ka hoʻohana ʻana i nā papa kiʻekiʻe o ka glimepiride e hoʻoweliweli. I ka hoʻomanawanui me ka maʻi diabetes, ka nalowale o ka ʻike, nā neurological disorders, hypoglycemic coma hiki. I nā hihia koʻikoʻi, hiki i ka hāʻule pinepine i ke kō ke hoʻopau i nā lā he nui.

ʻO ka maʻi overdose - ka lavage gastric, nā aihue, e hoʻihoʻi i ka normoglycemia ma ka hoʻolaha ʻana i ka glucose i loko o kahi vein.

Nā Hoʻohui

I kekahi mau hihia, lawe i ka lāʻau Glimepiride hiki ke hōʻeha i ka olakino:

  • HS, nā makahiki o nā keiki;
  • hapaka, maʻi maʻi gestational;
  • i nā kūlana koʻikoʻi o ka hepatic a i ʻole ka pale ʻole. ʻO ke hoʻohana ʻana i nā papa glimepiride i loko o nā maʻi dialysis ʻaʻole i aʻo ʻia;
  • ua hōʻoia ʻia i ka maʻi diabetes. Inā hele a nānā mai nā ʻano maʻi maʻi maʻi (Modi, latent), hiki i ke koho ʻana o ka glimepiride;
  • nā hopena paʻa o ka maʻi maʻi. Pono e hoʻopau ʻia ka hypoglycemia ma mua o ka lawe ʻana i ka paila hou. No nā ʻano āpau o ka maʻi maʻi maʻi a me ka mua, ua pau nā keʻena papa;
  • inā kūleʻa ka maʻi lolo i kekahi o nā mea i papa ʻia o ka papa, hiki i nā ʻano anaphylactic me ke hoʻohana mau;
  • ma muli o ka loaʻa ʻana o nā papa i ka lactose, ʻaʻole hiki iā lākou ke kiʻi ʻia e nā poʻe maʻi me nā maʻi hoʻoili o kona assimilation.

Paipai ʻia ke aʻo i ka mālama kūikawā ma ka hoʻomaka ʻana o ka mālama ʻana me ka glimepiride, ma ke ʻano o ke koho ana i ka make, i ka wā e hoʻololi ai i kahi mau meaʻai a i ʻole ke ola ʻana. Hiki i ka Hyperglycemia ke alakaʻi i nā hōʻeha, nā maʻi a me nā maʻi, ʻo ia ka mea i hele pū ʻia e ke kuni. I ka wā hoʻoponopono, ma ke ʻano, hiki i ka hypoglycemia.

Hiki i nā maʻi Digest ke hoʻololi i ka hopena o nā papa inā he pilikia ka ʻili ʻana. ʻO ka hemahema o ka huaʻai o ka dehydrogenase glucose-6-phosphate i ka wā e lawe ai i ka lāʻau Glimepiride e hōʻeha.

Nā kikowaena Glimepiride

Loaʻa nā analogues ma Rusia i hoʻopaʻa inoa ʻia ma ka papa inoa o nā lāʻau lapaʻau.

ʻO ka huiTagu inoaMea hanaAupuni kūkulu
ʻO nā analogs piha, ʻo ka waiwai hana he glimepiride wale nō.AmarilSanofiKelemania
GlimepirideʻO Rafarma, Atoll, Pharmproekt, Verteks, Pharmstandard.Lūkia
Nā InstolitHoʻohālikelike
Canon GlimepirideCanonpharma
HaipuleAkrikhin
KahiolaPūnaewele Actavisʻ .lelo
Glimepiride-tevaPlivaKroasia
GlemazKimika MontpellierʻApenekia
GlemaunoWokhardIndia
MeglimideKrkaKeolikiia
HoʻolālāShin Pung PharmaKoria
Nā hui kikoʻī, nā hui hoʻohui i loaʻa ka glimepiride.Avandaglim (me nā rosiglitazone)GlaxoSmithKleinLūkia
Amaryl M (me ka metformin)SanofiFarani

Wahi a nā loiloi o ka maʻi maʻi, nā kiʻekiʻe kiʻekiʻe o nā huahana Amaril ʻo Glimepiride-Teva a me Glimepiride hana kūloko. Loaʻa pinepine nā koena loea i loko o ka hale kūʻaiʻai.

ʻO Glimepiride a i Diabeton - ʻoi aku ka maikaʻi

ʻO ka mea hana ma Diabeton he gliclazide, PSM 2 mau hanauna. Aia ka papa papa i kahi ʻano kūikawā, kahi e hāʻawi ai i ka kahe kahe mau o ka lāʻau i loko o ke koko. Ma muli o kēia, ua liʻiliʻi ka maʻi Diabeton MV i ka hypoglycemia ma mua o gliclazide maʻamau. I nā PSM āpau i loaʻa, ʻo ia ka lōkika glyclazide a me ka glimepiride i ʻōlelo ʻia e nā endocrinologists me he mau palekana loa. Loaʻa iā lākou kahi hopena like-gula hoʻohaʻahaʻa i nā dosages hoʻohālikelike (1-6 mg no glimepiride, 30-120 mg no gliclazide). ʻO ke keena o ka hypoglycemia i kēia mau lāʻau kokoke ke kokoke.

He liʻiliʻi ʻokoʻa nā maʻi Diabeton a me Glimepiride. ʻO ka mea nui loa ia lākou:

  1. Kuhi ʻia ka Glimepiride e kahi palena haʻahaʻa o ka ulu ʻana o ka insulin / hoʻemi i ka glucose - 0,03. I ka Diabeton, kēia hōʻailona he 0,07. ʻO ka mea i ka wā e lawe ai i nā papa glimepiride, ua hōʻemi ʻia ka nui o ka insulin, ua emi ka nui o ka maʻi maʻi, hōʻemi ka pale ʻana i ka insulin, a ʻoi aku ka lōʻihi o nā cell beta.
  2. Aia nā ʻikepili mai nā noiʻi i hōʻoia i ka holomua o ke kūlana o nā mea maʻi me nā mākeke o ka ʻōnaehana cardiovascular ma hope o ka hoʻololi ʻana mai Diabeton a Glimepiride.
  3. I nā mea maʻi e lawe ana i ka metformin me glimepiride, hoʻemi iki ka make ma mua o nā maʻi maʻi maʻi i kauoha ʻia i ka mālama ʻana me gliclazide + metformin.

ʻO Glimepiride a i ʻole Amaryl - ʻoi aku ka maikaʻi

ʻO Amaril kahi lāʻau lapaʻau mua i hana ʻia e kekahi o nā alakaʻi i ka mākeke o nā lāʻau antidiabetic, hopohopo ʻo Sanofi. ʻO nā haʻawina a pau i hōʻike ʻia ma luna nei ua lawe ʻia me ka komo ʻana o kēia lāʻau lapaʻau.

Eia nō naʻe, ʻo ka hoʻomākaukau ʻana o ka glimepiride ma lalo o nā inoa inoa like e ʻelima mau lālā Lūkini. ʻO lākou he generics, a i ʻole nā ​​analogues, nā like a like a me ka like paha i nā mea like. Loaʻa lākou a pau e like me Amaril. ʻO ka ʻokoʻa i ke kumukūʻai ma muli o ka manaʻo ʻole o kēia mau lāʻau i ka holo ʻana i nā hoʻokolohua a pau e pono ai ke hoʻopaʻa inoa i kahi lāʻau hou. Hoʻomoʻa ʻia ke kaʻina hana no nā loiloi, ua lawa ia no ka mea hana ʻana e hōʻoia i ka kaulike o ka biolo ʻana o kāna mau papa i ka Amaril mua. ʻOkoʻa paha ka pae o ka hoʻomaʻemaʻe, nā ʻoliʻoli, ʻokoʻa papa.

ʻOiai ke kūlike nei o nā loiloi ma Amaril a me Russian Glimepirides, aia kekahi mau maʻi maʻi makemake i nā lāʻau lapaʻau mua wale nō. Inā he kānalua manaʻo inā hana ʻoi aku ka hana o ka mea maʻamau, ʻoi aku ka maikaʻi o ke kūʻai ʻana iā Amaril, no ka mea, he mea koʻikoʻi ka hilinaʻi i ka mālama i kuhikuhi ʻia. ʻO ka hopena placebo pili i kēlā me kēia a loaʻa i kahi hopena kūpono i ko mākou pono.

ʻO ke kumukūʻai a me ka waiho ʻana

Glimepiride uku kumukūʻai, 4 mg dosis:

Kauka-kalepaMea hanaʻO ke kumu kūʻai, rub.
AmarilSanofi1284 (3050 mau rubles no ka pā o 90 pcs.)
GlimepirideAlanui276
Ozone187
Lapaʻau316
Lapaʻau184
Canon GlimepirideCanonpharma250
HaipuleAkrikhin366

ʻO nā analogues maʻalahi loa e hoʻolālā ʻia e Samara Ozone a me Pharmproject mai St. Petersburg. Ke kūʻai nei kēlā me kēia mau huahana i nā huahana kūloko mai nāʻoihana lapaʻau i India.

Loaʻa ka ola o nā pale o nā mea hana like ʻole a he 2 a he 3 paha makahiki. Kahi pono nā koi no ka mahana mālama - ʻaʻole i kiʻekiʻe ma mua o 25 degere.

Nā Hōʻike Kokua Diabetes

Review o Lyudmila. ^ E Ha yM. Hoʻomaka ʻo Glimepiride e inu me 2 mg, ʻĀnō ʻo dosis ka 2 mg ma mua o ka ʻaina kakahiaka a me ka ʻaina awakea. Mākou e kūʻai i kekahi o kā mākou Glimepiride, no ka mea, ua aloha nui wau iā Amaril. Ua hāʻule ke gula mai 13 a 7, noʻu he hopena maikaʻi loa kēia. ʻO ke kūlana wale nō kahi kaʻai palekana e inu i ka paila ma mua o kahi kīʻaha koʻikoʻi, inā ʻaʻole e emi nui ka holi. ʻAʻole pono ke kofe me kahi lole ahi, loaʻa iaʻu kahi paila no ka ʻaina kakahiaka me kahi mea a me ka waiū.
ʻIke ʻia e Alexey. ^ E Ha yM. Ua kauoha ʻia au iā Glimepiride i hoʻopili ʻia i Glucophage. I loko o nā lāʻauʻai, he nui nā koho no kēia lāʻau lapaʻau mai nā mea hana like. ʻOiai ke nānā pinepine nei au i ke kō koko, hiki wawe wau e ʻōlelo me ka hilinaʻi ʻaʻole i loaʻa nā papa Vertex i ka hopena therapeutic. A ʻo ka lāʻau like ʻole mai Kursk mai Pharmstandard-Leksredstva e alakaʻi i ka hopena mau i ka hopena mau a mālama i ka kō i ke kō a pili i ka maʻamau. ʻAe wau i ka mua o ka lāʻau lapaʻau maʻamau ka hoʻopunipuni maʻamau mai kahi mea hana hili ʻole, a hiki i ka heluhelu ʻana i nā loiloi hope loa. E hoʻohuli ʻo kēlā me kēia maʻi ka lāʻau lapaʻau ponoʻī, ʻoiai ka aneane like like.
Hōʻike ʻo Jeanne. ^ E Ha yM. Ma hope o ka kipa hou ʻana i ka endocrinologist, ua hoʻololi lākou i koʻu ʻano maʻi a kuhikuhi iā Glimepiride. Wahi a ke kauka, hoʻohaʻahaʻa loa ia i ke kō a maikaʻi loa a ʻoi aku ka maikaʻi ma mua o ka Maninil aʻu i inu ai ma mua. Hana ʻia kēia lāʻau lapaʻau e nā hui he nui. ʻO ka wā mua aʻu i kūʻai ai iā Glimepirid Canon, ua loaʻa iaʻu ka hopena, no laila ke hoʻomau nei wau e inu. Maʻa liʻiliʻi nā papa, maʻalahi maʻalahi. Maikaʻi nui ke aʻo, hiki iā ʻoe ke ʻike i ke kuleana koʻikoʻi o ka mea hana. ʻO nā mea ʻaoʻao ka mea pīhoihoi wale, ua laki wau ʻaʻole i hālāwai me lākou.

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