ʻO Glimepiride (Glimepiride) - nā kūlana hou o ka hoʻomākaukau ʻana o ka sulfonylurea. Me ka maʻi o ka maʻi diabetes, e hoʻonui ana i ka hoʻokuʻu o ka insulin i loko o ke koko, e hōʻemi ana i ka glycemia. No ka mea mua, ua hoʻohana ʻia kēia ʻano hana e Sanofi i mau papa ʻo Amaryl. Ke hana ʻia nei nā lāʻau lapaʻau me kēia ʻano hana a puni ka honua.
Hoʻomaʻi maikaʻi ʻia ka glimepiride Lūkini, me ka hoʻohaʻahaʻa maikaʻi i ke kō, e hōʻemi i ka hopena o nā ʻaoʻao, e like me nā papa mua. Hōʻike nā hōʻike i ka maikaʻi loa a me ka uku haʻahaʻa o nā lāʻau lapaʻau home, no laila ʻaʻole ia he mea kupanaha no ka makemake pinepine o ka maʻi maʻi maʻi Glimepiride i ka Amaril kumu.
ʻO wai e hōʻike ʻia ana he glimepiride
Hoʻokomo ʻia ka lāʻau lapaʻau no ka hana maʻamau o ka glycemia wale nō i ka maʻi maʻi type 2. ʻAʻole ia e kuhikuhi i ka ʻōlelo aʻo i ka wā e hoʻāpono ʻia ka mālama ʻana me Glimepiride, ʻoiai ke koho ʻana i kahi lāʻau lapaʻau kūikawā a ʻo kāna mea nui ka paʻakikī o ke kauka. E hoʻāʻo mākou e nānā i ka mea e hōʻike ʻia nei i ka lāʻau Glimepiride.
Haka ka Sugar i ka maʻi diabetes no nā kumu ʻelua: no ka pale ʻana i ka insulin a me ka hoʻokaʻawale ʻana i ka hoʻokuʻu ʻana i ka insulin mai nā beta beta i loaʻa i ka pancreas. Ka hoʻomohala ʻia ke kūlohelohe insulin ma mua o ka puka ʻana o ka maʻi diabetes, ʻike ʻia i nā mea maʻi me ka momona a me nā prediabetes. ʻO ke kumu ke ʻai maikaʻi ʻole ʻana, nele i ka hoʻomaʻamaʻa, keu. Hoʻopili ʻia kēia ʻano me ka hoʻonui ʻana i ka insulin, ma kēia ʻano e hoʻāʻo ai ke kino e pale i ka pale ʻana o nā maʻi a hoʻomaʻemaʻe i ke koko o ka momona glucose. I kēia manawa, ʻo ka hoʻololiʻana i ke ʻano o ka hoʻololi ʻana i ke ola olakino a kuhikuhi i nā metformin, kahi lāʻau lapaʻau e hoʻōla maoli ana i ka pale ʻana i ka insulin.
ʻO ke kiʻekiʻe nui o ka glycemia o ka mea maʻi, ʻoi ka nui o ka hoʻomau ʻia o ka maʻi mellitus. Hoʻopili ʻia nā maʻi ʻoi a me ka hoʻohaʻahaʻa i ka huna ʻana i ka insulin, a hele hou ka hyperglycemia i ka mea maʻi. Wahi a nā kauka, i ka hopena o ka maʻi maʻi, ua loaʻa ka hemahema i ka ʻina o ka hapalua o nā maʻi. Ma kēia hoʻi i ka maʻi, i ka hoʻohui ʻana i ka insulin, nā lāʻau lapaʻau e hoʻoikaika ana i ka hana ʻana o nā hua beta e pono ke kuhikuhi. ʻO ka mea e ʻoi loa a me ka hopena o lākou he derivatives o ka olonylurea, pōkole PSM.
ʻO ka maʻi maʻi a me nā hoʻohaʻahaʻa manaʻo e hana ia i ka wā ma mua
- Ka hana maʻamau o ke kō -95%
- Hoʻokuʻuina o ka pua thrombosis - 70%
- Hoʻopau i kahi puʻuwai ikaika -90%
- Hoʻopau i ke kiʻekiʻe o ke koko - 92%
- ʻO ka hoʻonuiʻana i ka ikehu i ka wā, hoʻomaikaʻi i ka hiamoe i ka pō -97%
Wahi a nā mea i hōʻike ʻia i mua, e hōʻike mākou i nā hōʻailona no ka koho ʻana i ka lāʻau Glimepiride.
- ʻO ka nele o ka hana pono o ka meaʻai, ka hoʻomaʻamaʻa a me ka metformin.
- ʻIke ʻia e ka nānā ʻana i ka nele o kā lākou iho ponoʻī.
Hiki i ke ʻikepili ke hoʻohana i ka hoʻohana ʻana i ka lāʻau Glimepiride me ka insulin a me ka metformin. Wahi a nā loiloi, hele maikaʻi ka lāʻau me nā glitazones, gliptins, incretin mimetics, acarbose.
Ke ʻano o ka hana o ka lāʻau
ʻO ka hoʻokuʻu ʻana o ka insulin mai ka pancreas i ke kahe koko e hiki ke kūpono ma muli o nā kahui KATP kūikawā. Aia lākou ma kēlā me kēia kelepona ola a hoʻolako i ka kahe o ka pāhana ma o kona membrane. Ke paʻa ka hoʻāʻo ʻana o ka glucose i nā moku i loko o nā palena maʻamau, e wehe ʻia kēia mau kahawai ma nā cell beta. Me ka uluʻana o ka glycemia, pili lākou, kahi e hoʻoiho ai i ka calcium, a laila hoʻokuʻu i ka insulin.
ʻO ka lāʻau Glimepiride a me nā mea āpau PSM e pani hou loa, e hoʻonui ai i ka hana o ka insulin a me ka huna. ʻO ka nui o ka hāmeʻe i hoʻokuʻu ʻia i loko o ke koko wale nō e kau i ka dosage o glimepiride, a ʻaʻole ma ka pae o glucose.
I nā makahiki i hala iho nei, ua hānai ʻia a ua hoʻāʻo ʻia ka 3 mau hanauna, a he ʻano hou. ʻO ka hana o nā lāʻau lapaʻau mua, ka chlorpropamide a me ka tolbutamide, i kaha nui ʻia e nā lāʻau maʻi maʻi maʻamau, ka mea e alakaʻi pinepine ai i ka hypoglycemia koʻikoʻi. Me ka hiki ʻana o ka hanauna PSM 2, glibenclamide, glyclazide a me glipizide, ua pane ʻia kēia pilikia. Pili lākou i nā mea ʻē aʻe he mauwaliwali loa ma mua o ka PSM mua. Akā, loaʻa i kēia mau lāʻau i nā pōkole: i ka hoʻopiʻi ʻana i ka meaʻai a me nā ukana, hoʻoulu lākou i ka hypoglycemia, alakaʻi i ka loaʻa ʻana o ka paona lohi, a no laila, he nui o ka pale ʻana i ka insulin. Wahi a kekahi mau noiʻi, hiki i nā hanauna PSM 2 ke hoʻopōʻino i ka hana naʻau.
I ka wā e hoʻokumu ai i ka lāʻau lapaʻau Glimepiride, ua lawe ʻia nā hopena o luna. Ua mālama lākou i ka hōʻemi iā lākou i ka hoʻomākaukau hou.
Loaʻa o Glimepiride ma luna o PSM o nā hanauna i hala.
- ʻO ka hopena o ka hypoglycemia i ka wā i lawe ʻia ai ka haʻahaʻa. Ua emi iki ka pilina o ka lāʻau me nā receptors ma mua o kāna hui hui hui, ʻoi aku, ʻo ke kino kekahi i mālama i nā hana pono e pale ai i ke kūmole o ka insulin me ka haʻahaʻa haʻahaʻa. Ke pāʻani nei i nā haʻuki, ʻaʻole hemahema o nā kīleʻaleʻa i ka meaʻai, nā glimepiride e hōʻeha i ka hypoglycemia haʻahaʻa ma mua o PSM. Hōʻike nā nānā i ke kō i ka wā e lawe ai i nā papa glimepiride e hāʻule ma lalo o ka maʻamau i ka 0.3% o nā maʻi maʻi.
- ʻAʻohe hopena ma ke kaupaona. ʻO ka nui o ka insulin i loko o ke koko e pale i ka wāwahi i ka momona, ʻo ka hypoglycemia pinepine e hāʻawi i ka nui o ka makemake a me ka hoʻokomo o ka caloric intake. ʻO Glimepiride ka palekana ma kēia hana. Wahi a nā mea maʻi, ʻaʻole ia e hoʻokau i ka paona, a me ka momona ʻo ia e hāʻawi pū i ka hoʻolilo ʻana.
- ʻO ka haʻahaʻa haʻahaʻa o nā maʻi cardiovascular. Hiki i ka PSM ke hoʻopili me nā kahawai KATP i loaʻa wale i ka pancreas, akā i nā paia o nā kīʻaha koko, e hoʻonui ana i ka hōʻeha o kā lākou pathology. Hana wale ka glimepiride lāʻau i ka pancreas, no laila e ʻae ʻia no ka poʻe maʻi maʻi me ka angiopathy a me ka maʻi puʻuwai.
- Hōʻike nā ʻōkuhi i ka hiki o Glimepiride e hōʻemi i ka pale ʻana i ka insulin, hoʻonui i ka synthesis glycogen, a me ka pale ʻana i ka hana glucose. ʻOi aku ka hana o ka haʻahaʻa ma mua o ka metformin, akā ʻoi aku ka maikaʻi ma mua o ke koena o PSM.
- Ke hana wikiwiki nei ka lāʻau lapaʻau ma mua o nā mea analogue, ke koho ʻana i kahi hapa a me ka loaʻa ʻana o ka uku no ka maʻi diabetes no ka liʻiliʻi.
- Hoʻopuka nā papa Glimepiride i nā lua o ka sela o ka insulin, no laila, hōʻemi lākou i ka glycemia wikiwiki ma hope o ka ʻai ʻana. Hana nā lāʻau kahiko i ka mahele 2.
ʻĀnō
ʻO ka dosage maʻamau o ka glimepiride, nā mea hana i hoʻoponopono, ʻo ia ka 1, 2, 3, 4 mg o ka waiwai ikaika i kahi papa. Hiki iā ʻoe ke koho i ka helu kūpono o ka lāʻau lapaʻau me ka helu kūpono, inā pono, e maʻalahi nā loli a hoʻololi ʻia. Ma ke kānāwai, ua paʻa ka papa i ka pilikia, e hiki ai iā ʻoe ke hoʻokaʻawale iā ia i ka hapalua.
Hoʻonui ka hopena o ke kōpaʻa ʻana i ke kō me ka hoʻonui ʻana i ka pākaukau mai ka 1 a i ka 8 mg. Wahi a nā maʻi maʻi, nui ka poʻe e pono ai ka 4 mg a i ʻole ka liʻiliʻi o ka glimepiride e uku no ka maʻi maʻi. Hiki i nā dosages nui i nā maʻi me ka decompensated diabetes a me kahi kūʻē o ka insulin. Pono lākou e hoʻohaʻahaʻa i ka wā e hoʻokau ke aupuni - e hoʻomaikaʻi i ka naʻau o ka insulin, e emi ana ke kaumaha, a me ke ʻano o ke ʻano o ke ʻano.
ʻO ka make i manaʻo ʻia i loko o ka maʻi glycemia (ka hoʻohālikelike hoʻohālikelike e like me ke aʻo ʻana):
Dosis mg | Hoʻemi ka hana | ||
Hoʻolaha kūmole, mmol / l | Hoʻopau i ka kūpaʻa postprandial, mmol / l | Hologlobin glycated,% | |
1 | 2,4 | 3,5 | 1,2 |
4 | 3,8 | 5,1 | 1,8 |
8 | 4,1 | 5,0 | 1,9 |
ʻO ka ʻike mai nā ʻōlelo ʻōlelo i ka kaina e koho ai i ka pākaukau i makemake ʻia:
- ʻO ka dosage hoʻomaka e 1 mg. ʻO ka maʻa iki i nā maʻi maʻi me ka hoʻohaʻahaʻa haʻahaʻa ʻia, a me nā poʻe maʻi me ka hiki ʻole o ka renal. ʻAʻole pili ka maʻi o ka naʻau i ka nui o ka nui.
- Hoʻonui ʻia ka nui o nā papa a hiki i ka loaʻa ʻana o nā mea makemake gula. I mea e pale ʻole ai i ka hypoglycemia, hoʻonui pinepine ʻia ka nui, ma nā manawa o 2 mau pule. I kēia manawa, pono nā ana o ka nui o ka glycemia ma mua o ka maʻamau.
- Keʻano ulu lāʻau: a hiki i 4 mg, e hoʻohui 1 mg, ma hope - 2 mg. Ke hele i ka glucose i ka maʻamau, a kāpae i ka hoʻonui ʻana i ka nui o nā papa.
- ʻO ka dosis ʻokoʻa loa ka ʻelee loa he 8 mg, ua mahele ʻia i nā ʻāpana he: 2 a me 4 mg paha; 3 a me 2 mg.
Nā ʻōlelo kikoʻī no ka hoʻohana
ʻO ka hopena kiʻekiʻe o ka lāʻau lapaʻau e hiki mai ana ma kahi o 2 mau hola mai kona hoʻoponopono. I kēia manawa, emi iki ka glycemia. Ka mea, inā inu ʻoe iā Glimepiride hoʻokahi manawa i ka lā, e lilo kēlā huakaʻi nui, inā ʻoe e hoʻokaʻawale i ka ʻawa ma 2 mau manawa, e lilo ana ka hopena, akā he ʻoluʻolu. Hoʻomaopopo i kēia hiʻohiʻona o ka lāʻau lapaʻau, hiki iā ʻoe ke koho i ka manawa o ka hoʻokomo. Manaʻo ia e hāʻule ka papa kiʻekiʻe o ka hana ma ka manawa ma hope o ka manawa piha o ka ʻai ʻana me nā kalapona, a ʻaʻole kū pū me ka hana pilikino i hoʻolālā ʻia.
Hoʻopili ʻia ka hopena o ka hypoglycemia e kaʻai ʻole a i ʻole ka hōʻemi kino ʻana, nā hana kiʻekiʻe me ka naʻau ʻole i ka nui o ka paʻakai, nā maʻi ʻeha, nā hopena endocrine, a me kekahi mau lāʻau lapaʻau.
Hoʻopau ka lāʻau lapaʻau e like me ke kuhikuhi ʻana:
Ka kuhikuhi ʻana o ka hana | Ka papa inoa o nā lāʻau |
Hoʻonui i ka hopena o nā papa, hoʻonui i ka hōʻeha o ka hypoglycemia. | ʻO ka insulin, nā hui antidiabetic papa. Steroids, testosterone, kekahi antibiotics (chloramphenicol, tetracycline), streptocide, fluoxetine. Antitumor, antiarrhythmic, antihypertensive, antifungal agents, fibrates, anticoagulants. |
E hoʻonāwaliwali i ka hopena o ke kōpoki, ke hoʻonui iki ʻana i ka hoʻoleʻa o ka lāʻau lapaʻau Glimepiride pono. | Diuretics, glucocorticoids, adrenomimetics, estrogens, triiodothyronine, thyroxine. ʻO nā dosis nui o ka waiū B3, mālama lōʻihi a me nā laxatives. |
Hoʻonui kēia i nā hōʻailona o ka hypoglycemia, kahi mea paʻakikī iā ia i ka ʻike. | Clonidine, sympatholytics (reserpine, octadine). |
Palapala hoʻohālikelike o ka alkoholie mai nā kuhikuhi glimepiride: hiki i nā mea inu ʻona ke hoʻonui i ka hopena o ka hopena o ka lāʻau lapaʻau, hiki ʻole i ka mea nānā ke kō i ke kō koko. Wahi a nā loiloi, e kū pinepine ka glucose i ka wā pāʻina, akā ia po ke hāʻule nui nei, a hiki i ka hypoglycemia koʻikoʻi. Hoʻopau ikaika ka inu ʻana i ka uku no ka maʻi diabetes, ʻaʻohe mea e kau ʻia ai ka mālama ʻana.
Nā hiʻohiʻona o ka lawe ʻana i nā keiki a me nā wahine hāpai
I ka wā e hoʻohana ai i ka wā hāpai, komo ka lāʻau Glimepiride i ke koko o ka wahine hāpai a hiki i ka hypoglycemia ma loko. Eia hoʻi, hoʻokomo ka waiwai i ka waiū umauma, a mai laila i loko o ka digestive tract o ke pēpē. I ka wā hapai a me HB, lawe pio iā Glimepiride. Hoʻololi ka FDA (American Medicines Authority) iā Glimepiride i kahi papa C. ʻO kēia ke ʻano o nā noiʻi holoholona i hōʻike ʻia he hopena maikaʻi ʻole o ka pūpū.
ʻAʻole i kuhikuhi ʻia ʻo Glimepiride no nā keiki, ʻoiai inā lākou e hōʻike ana me ka maʻi maʻamau o ka 2. ʻAʻole i hōʻike ʻia ka lāʻau lapaʻau i nā hoʻokolohua e pono ai, ʻaʻole i aʻo ʻia ka hopena i ka mea ulu nui.
Kahi papa inoa o nā hopena ʻaoʻao
ʻO ka hopena koʻikoʻi nuiʻole o Glimepiride he hypoglycemia. Wahi a nā hoʻokolohua, ʻoi loa ka hoʻoweliweli ʻia o kona pilikia ma mua o ka mana o PSM ikaika - glibenclamide. Holo i ka Sugar, ka mea i alakaʻi ai i ka hoʻokipa a me nā poʻe e hoʻokaʻawale i nā glucose, i loko o nā mea maʻi ma Glimepiride - 0.86 ʻāpana ma kahi o 1000 mau makahiki. Hoʻohālikelike me ka glibenclamide, kēia ʻōkuhi he 6.5 mau manawa haʻahaʻa. ʻO ka pane kūponoʻole o ka lāʻau, ʻo ia ka hoʻohaʻahaʻa haʻahaʻa o ka hypoglycemia i ka wā o ka hana hoʻoikaika a hoʻolōʻihi.
ʻO nā hopena koʻikoʻi koʻikoʻi o ka glimepiride mai nā kuhikuhi no ka hoʻohana ʻana:
Kahi ʻāina kue ʻole | ʻO keʻano | Auawaea |
ʻŌnaehana ʻōnaehana | Allergic hopena pili. Hiki mai ma o ka glimepiride wale nō, akā ma nā mea ʻē aʻe o ka lāʻau lapaʻau. I kēia hihia, ke hoʻololi nei i ka lāʻau lapaʻau me ka mea hoʻohana o kekahi mea hana hou e kōkua paha. ʻO nā maʻi kūlohelohe e koi ana i ka haʻalele koke o ka lāʻau e laha loa. | < 0,1% |
ʻŌpala Gastrointestinal | He kaumaha, naʻau o ka piha piha, ʻeha o ka ʻōpū. Nā maʻi ʻeha, maʻi ʻoluʻolu. | < 0,1% |
Koko | Hoʻoholo i ka helu platelet. Aia kahi hōʻike no kahi hihia kaʻawale o thrombocytopenia koʻikoʻi. | < 0,1% |
ʻO ka hōʻemi ʻana i ka nui o nā sela keʻokeʻo keʻokeʻo, nā ʻāpana koko ʻulaʻula. Hyponatremia. | nā hihia kūikawā | |
Pāʻālua | Hoʻonui ka nui o nā enzyme hepatic i ke koko, hepatitis. Hiki i nā ala āpau ke kūkulu i ka palaualelo, no laila koi ko lākou hiʻohiʻona e hoʻokuʻu i ka lāʻau. Ma hope o ke hoʻopauʻana, e nalowale nā neʻeʻana. | nā hihia kūikawā |
ʻIli | Photosensitivity - kahi mālamalama i ka ʻike pono i ka lā. | nā hihia kūikawā |
Nā Organs o ka hihiʻo | I ka hoʻomaka ʻana o ka hoʻōla a me ka piʻi ʻana o ka maʻa, hiki ke hiki ke hele i ka ʻike maka transientment. Hoʻopili ʻia lākou e ke kaona nui o ke kō a e hoʻomake ma kā lākou pono iho i ka wā e hoʻohālikelike ai nā maka i nā kūlana hou. | ʻaʻole i wehewehe ʻia |
Aia kekahi leka e pili ana i ka hiki ke hūnā ʻia o ka hormone antidiuretic. Ke hoʻāʻo ʻia nei kēia ʻaoʻao kūpono, no laila ʻaʻole i komo pū i nā ʻōlelo aʻoaʻo.
Hiki i kahi overdose
ʻAʻole ʻano he aanaha a maʻalahi ke kaila ʻo Glimepiride, ke waiho mau nei ia i kahi derivative sulfonylurea, ʻo ia ke ʻano he overdose kona hopena i ka hypoglycemia. Loaʻa kēia hopena ʻaoʻao i ka ʻoihana o ka lāʻau lapaʻau, hiki ke pale wale i ka nānā pono ʻana i ka pauʻa.
ʻO ka rula no ka pale ʻana o ka hypoglycemia mai nā ʻōlelo i hoʻohana ʻia: inā i ʻike ʻia ka papa ʻaila Glimepiride, a ʻaʻohe hoʻi i maopopo i ka inu ʻana i ka lāʻau, ʻaʻole e hoʻonui ʻia ka ʻai ma ka hopena aʻe, inā paha ua kū mai ke kō koko.
Hiki ke hoʻopau i ka hypoglycemia me ka glucose - wai momona, kaʻaila a me ke kō. ʻAʻole pono e kali no nā hiʻohiʻona hiʻohiʻona, lawa nā glycemic data. ʻOiai ka hana ʻana i ka lāʻau lapaʻau i kahi kokoke i hoʻokahi lā, hiki i ke kō ke hoʻōla i ka maʻamau ke hoʻomau mau i nā helu i nā pōʻino. I kēia manawa āpau pono ʻoe e nānā i ka glycemia, mai haʻalele i ka maʻi maʻi maʻi wale.
Ka manawa paʻa nui o ka wā nui, ka lōʻihi o ka hoʻohana ʻana i nā papa kiʻekiʻe o ka glimepiride e hoʻoweliweli. I ka hoʻomanawanui me ka maʻi diabetes, ka nalowale o ka ʻike, nā neurological disorders, hypoglycemic coma hiki. I nā hihia koʻikoʻi, hiki i ka hāʻule pinepine i ke kō ke hoʻopau i nā lā he nui.
ʻO ka maʻi overdose - ka lavage gastric, nā aihue, e hoʻihoʻi i ka normoglycemia ma ka hoʻolaha ʻana i ka glucose i loko o kahi vein.
Nā Hoʻohui
I kekahi mau hihia, lawe i ka lāʻau Glimepiride hiki ke hōʻeha i ka olakino:
- HS, nā makahiki o nā keiki;
- hapaka, maʻi maʻi gestational;
- i nā kūlana koʻikoʻi o ka hepatic a i ʻole ka pale ʻole. ʻO ke hoʻohana ʻana i nā papa glimepiride i loko o nā maʻi dialysis ʻaʻole i aʻo ʻia;
- ua hōʻoia ʻia i ka maʻi diabetes. Inā hele a nānā mai nā ʻano maʻi maʻi maʻi (Modi, latent), hiki i ke koho ʻana o ka glimepiride;
- nā hopena paʻa o ka maʻi maʻi. Pono e hoʻopau ʻia ka hypoglycemia ma mua o ka lawe ʻana i ka paila hou. No nā ʻano āpau o ka maʻi maʻi maʻi a me ka mua, ua pau nā keʻena papa;
- inā kūleʻa ka maʻi lolo i kekahi o nā mea i papa ʻia o ka papa, hiki i nā ʻano anaphylactic me ke hoʻohana mau;
- ma muli o ka loaʻa ʻana o nā papa i ka lactose, ʻaʻole hiki iā lākou ke kiʻi ʻia e nā poʻe maʻi me nā maʻi hoʻoili o kona assimilation.
Paipai ʻia ke aʻo i ka mālama kūikawā ma ka hoʻomaka ʻana o ka mālama ʻana me ka glimepiride, ma ke ʻano o ke koho ana i ka make, i ka wā e hoʻololi ai i kahi mau meaʻai a i ʻole ke ola ʻana. Hiki i ka Hyperglycemia ke alakaʻi i nā hōʻeha, nā maʻi a me nā maʻi, ʻo ia ka mea i hele pū ʻia e ke kuni. I ka wā hoʻoponopono, ma ke ʻano, hiki i ka hypoglycemia.
Hiki i nā maʻi Digest ke hoʻololi i ka hopena o nā papa inā he pilikia ka ʻili ʻana. ʻO ka hemahema o ka huaʻai o ka dehydrogenase glucose-6-phosphate i ka wā e lawe ai i ka lāʻau Glimepiride e hōʻeha.
Nā kikowaena Glimepiride
Loaʻa nā analogues ma Rusia i hoʻopaʻa inoa ʻia ma ka papa inoa o nā lāʻau lapaʻau.
ʻO ka hui | Tagu inoa | Mea hana | Aupuni kūkulu |
ʻO nā analogs piha, ʻo ka waiwai hana he glimepiride wale nō. | Amaril | Sanofi | Kelemania |
Glimepiride | ʻO Rafarma, Atoll, Pharmproekt, Verteks, Pharmstandard. | Lūkia | |
Nā Instolit | Hoʻohālikelike | ||
Canon Glimepiride | Canonpharma | ||
Haipule | Akrikhin | ||
Kahiola | Pūnaewele Actavis | ʻ .lelo | |
Glimepiride-teva | Pliva | Kroasia | |
Glemaz | Kimika Montpellier | ʻApenekia | |
Glemauno | Wokhard | India | |
Meglimide | Krka | Keolikiia | |
Hoʻolālā | Shin Pung Pharma | Koria | |
Nā hui kikoʻī, nā hui hoʻohui i loaʻa ka glimepiride. | Avandaglim (me nā rosiglitazone) | GlaxoSmithKlein | Lūkia |
Amaryl M (me ka metformin) | Sanofi | Farani |
Wahi a nā loiloi o ka maʻi maʻi, nā kiʻekiʻe kiʻekiʻe o nā huahana Amaril ʻo Glimepiride-Teva a me Glimepiride hana kūloko. Loaʻa pinepine nā koena loea i loko o ka hale kūʻaiʻai.
ʻO Glimepiride a i Diabeton - ʻoi aku ka maikaʻi
ʻO ka mea hana ma Diabeton he gliclazide, PSM 2 mau hanauna. Aia ka papa papa i kahi ʻano kūikawā, kahi e hāʻawi ai i ka kahe kahe mau o ka lāʻau i loko o ke koko. Ma muli o kēia, ua liʻiliʻi ka maʻi Diabeton MV i ka hypoglycemia ma mua o gliclazide maʻamau. I nā PSM āpau i loaʻa, ʻo ia ka lōkika glyclazide a me ka glimepiride i ʻōlelo ʻia e nā endocrinologists me he mau palekana loa. Loaʻa iā lākou kahi hopena like-gula hoʻohaʻahaʻa i nā dosages hoʻohālikelike (1-6 mg no glimepiride, 30-120 mg no gliclazide). ʻO ke keena o ka hypoglycemia i kēia mau lāʻau kokoke ke kokoke.
He liʻiliʻi ʻokoʻa nā maʻi Diabeton a me Glimepiride. ʻO ka mea nui loa ia lākou:
- Kuhi ʻia ka Glimepiride e kahi palena haʻahaʻa o ka ulu ʻana o ka insulin / hoʻemi i ka glucose - 0,03. I ka Diabeton, kēia hōʻailona he 0,07. ʻO ka mea i ka wā e lawe ai i nā papa glimepiride, ua hōʻemi ʻia ka nui o ka insulin, ua emi ka nui o ka maʻi maʻi, hōʻemi ka pale ʻana i ka insulin, a ʻoi aku ka lōʻihi o nā cell beta.
- Aia nā ʻikepili mai nā noiʻi i hōʻoia i ka holomua o ke kūlana o nā mea maʻi me nā mākeke o ka ʻōnaehana cardiovascular ma hope o ka hoʻololi ʻana mai Diabeton a Glimepiride.
- I nā mea maʻi e lawe ana i ka metformin me glimepiride, hoʻemi iki ka make ma mua o nā maʻi maʻi maʻi i kauoha ʻia i ka mālama ʻana me gliclazide + metformin.
ʻO Glimepiride a i ʻole Amaryl - ʻoi aku ka maikaʻi
ʻO Amaril kahi lāʻau lapaʻau mua i hana ʻia e kekahi o nā alakaʻi i ka mākeke o nā lāʻau antidiabetic, hopohopo ʻo Sanofi. ʻO nā haʻawina a pau i hōʻike ʻia ma luna nei ua lawe ʻia me ka komo ʻana o kēia lāʻau lapaʻau.
Eia nō naʻe, ʻo ka hoʻomākaukau ʻana o ka glimepiride ma lalo o nā inoa inoa like e ʻelima mau lālā Lūkini. ʻO lākou he generics, a i ʻole nā analogues, nā like a like a me ka like paha i nā mea like. Loaʻa lākou a pau e like me Amaril. ʻO ka ʻokoʻa i ke kumukūʻai ma muli o ka manaʻo ʻole o kēia mau lāʻau i ka holo ʻana i nā hoʻokolohua a pau e pono ai ke hoʻopaʻa inoa i kahi lāʻau hou. Hoʻomoʻa ʻia ke kaʻina hana no nā loiloi, ua lawa ia no ka mea hana ʻana e hōʻoia i ka kaulike o ka biolo ʻana o kāna mau papa i ka Amaril mua. ʻOkoʻa paha ka pae o ka hoʻomaʻemaʻe, nā ʻoliʻoli, ʻokoʻa papa.
ʻOiai ke kūlike nei o nā loiloi ma Amaril a me Russian Glimepirides, aia kekahi mau maʻi maʻi makemake i nā lāʻau lapaʻau mua wale nō. Inā he kānalua manaʻo inā hana ʻoi aku ka hana o ka mea maʻamau, ʻoi aku ka maikaʻi o ke kūʻai ʻana iā Amaril, no ka mea, he mea koʻikoʻi ka hilinaʻi i ka mālama i kuhikuhi ʻia. ʻO ka hopena placebo pili i kēlā me kēia a loaʻa i kahi hopena kūpono i ko mākou pono.
ʻO ke kumukūʻai a me ka waiho ʻana
Glimepiride uku kumukūʻai, 4 mg dosis:
Kauka-kalepa | Mea hana | ʻO ke kumu kūʻai, rub. |
Amaril | Sanofi | 1284 (3050 mau rubles no ka pā o 90 pcs.) |
Glimepiride | Alanui | 276 |
Ozone | 187 | |
Lapaʻau | 316 | |
Lapaʻau | 184 | |
Canon Glimepiride | Canonpharma | 250 |
Haipule | Akrikhin | 366 |
ʻO nā analogues maʻalahi loa e hoʻolālā ʻia e Samara Ozone a me Pharmproject mai St. Petersburg. Ke kūʻai nei kēlā me kēia mau huahana i nā huahana kūloko mai nāʻoihana lapaʻau i India.
Loaʻa ka ola o nā pale o nā mea hana like ʻole a he 2 a he 3 paha makahiki. Kahi pono nā koi no ka mahana mālama - ʻaʻole i kiʻekiʻe ma mua o 25 degere.