ʻO Lantus kekahi o nā mea hoʻokūkū mua o ka insulin manu. Loaʻa ʻia e ke kaila o ka asparagine acid amino me ka glycine ma ka kūlana 21 o ke kaulahao A a me ka hoʻohui ʻana i nā huina amino arginine ʻelua i nā kaulahao B i ka waʻa amino amino. ʻO kēia lāʻau lapaʻau e hana ʻia e kahi hui lāʻau lapaʻau Lūkini nui - Sanofi-Aventis. Ma ke ʻano o nā haʻawina he nui, ua hōʻike ʻia ʻo insulin Lantus ʻaʻole i hōʻemi wale ʻia i ka hopena o ka hypoglycemia i hoʻohālikelike ʻia me nā lāʻau lapaʻina o NPH, akā e hoʻomaikaʻi i ka metabolateko. Aia ma lalo kahi ʻōlelo pōkole no ka hoʻohana a me nā loiloi o ka maʻi maʻi.
ʻAtikala Kumuhana
- 1 ka hana Lapaʻau
- 2 Pūkau
- 3 hoʻokuʻu puka
- 4 Hōʻike
- 5 Hoʻopili ʻana me nā lāʻau lapaʻau ʻē aʻe
- 6 Nā ʻōmole
- 7 Ke hoʻololi i Lantus mai nā insulin ʻē aʻe
- 8 ʻO nā loulou
- 9 Insulin Lantus i ka wā hāpai
- 10 Pehea e mālama ai
- 11 I kahi e kūʻai ai, ke kumu kūʻai
- 12 ʻĀnō
Ka hana lāʻau lapaʻau
ʻO ka hana ikaika a Lantus ka insulin glargine. Loaʻa ʻia e ka genomb recombination ma ke ʻano he k-12 kaha o ke bacterium Escherichia coli. I kahi wahi kūʻokoʻa, hoʻokaʻawale iki ia, i loko o kahi mehe e hoʻokahe ana me ka hoʻokumu ʻana o ka microprecipitate, e kū mau ana a hoʻokuʻu iki i ka insulin. Ma muli o kēia, ua kūpono ʻo Lantus i kahi kaila hana maikaʻi a paʻa i nā hola 24.
ʻO nā waiwai nui a ka pharmacological:
- Hoʻololi i ka adsorption a me ka profile pae ʻole ma waena o 24 mau hola.
- ʻO ka hoʻomakeʻa ʻana o ka proteolysis a me ka lipolysis i adipocytes.
- Hoʻohālikelike ka mea hana i nā ʻonikena insulin 5-8 mau manawa ikaika.
- Ka hoʻoponopono o ka hoʻohuihui glucose, pale i ka hoʻomohala i ka glucose i loko o ka puʻuwai.
Hōʻike
I loko o 1 ml Lantus Solostar e loaʻa:
- 3.6378 mg o ka glargine insulin (e pili ana i 100 IU o ka insulin kanaka);
- 85% glycerol;
- wai no kahi pona;
- waikiko hydrochloric;
- m-cresol a me ka sodium hydroxide.
E hoʻokuʻu i ke ʻano
Lantus - kahi hopena kūleʻa no ka inikini sc, ua loaʻa i ka ʻano o:
- Nā pahu kaʻa no ka ʻōnaehana OptiClick (5pcs i kēlā me kēia pū);
- 5 syringe penens Lantus Solostar;
- OptiSet syringe pen i loko o hoʻokahi pahu i 5 pcs. (anuʻi 2 papa);
- 10 ml mau pahu (1000 mau pālākeke ma ke kumukūʻai)
Nā hōʻailona no ka hoʻohana ʻana
- ʻO nā pākeke a me nā keiki mai nā makahiki 2 me ke ʻano maʻi type 1.
- Kākau 2 diabetes mellitus (ma ka hihia o ka hiki ʻole o ka hoʻomākaukau ʻana i ka papa).
I loko o ka momona, kūpono kahi hui hui - Lantus Solostar a me Metformin.
Hoʻopili pū me nā lāʻau ʻē aʻe
Aia nā lāʻau lapaʻau e pili ana i ka metabolism, ʻo ka hoʻonui ʻana aʻe a i ka hoʻemi ʻana i ka pono o ka insulin.
Hoʻemi i ke kō: agio antidiabetic waha, sulfonamides, ACE inhibitors, salicylates, angioprotectors, monoamine oxidase inhibitors, antiarrhythmic dysopyramides, narcotic analgesics.
E hoʻonui i ke kō: thyroid thyne, diuretics, sympathomimetics, waha i ka ʻona a pakanui, deriviazine derivatives, protease inhibitors.
ʻO kekahi mau mea me ka hopena hypoglycemic a me ka hopena hyperglycemic. E pili ana kēia:
- beta blockers a me ka paʻakai lithium;
- waiʻona
- clonidine (lāʻau antihypertensive).
Nā Hoʻohui
- ʻAʻole pāpā ʻia ka hoʻohana ʻana i nā maʻi i loaʻa i ka intolerance i ka glargine insulin a i ʻole nā mea kōkua.
- Hypoglycemia.
- Ka hoʻomaʻemaʻe ʻana i ka ketoacidosis maʻi.
- Na keiki malalo o na makahiki 2.
Loaʻa ʻole paha nā ʻano ʻino e koi, i ʻōlelo nā ʻōlelo aʻoi paha:
- lipoatrophy a lipohypertrophy paha;
- kūlohelohe (kūwau a Quincke, kūwī āpau, bronchospasm);
- nā ʻeha a me ka lohi i ke kino o nā paʻakai sodium;
- hoʻoulua ʻia a me ka ʻike hoʻokaumaha ʻike.
Ke ala e hele ai i ka Lantus mai i ka insulin ʻē aʻe
Inā hoʻohana ka mea maʻi ma ka insulins medium-duration, a laila ke hoʻololi nei i Lantus, ua loli ka nui o ka nui a me ka hoʻonoho o ka lāʻau. Pono e lawe ʻia ka hoʻololi o ka insulin i ka haukapila.
Inā mālama ʻia nā NPul insulins (Protafan NM, Humulin, etc.) i ʻelua manawa i ka lā, a laila hoʻohana pinepine ʻia ʻo Lantus Solostar i ka manawa 1. I ka manawa like, i mea e hoʻemi ai i ka hopena o ka hypoglycemia, pono e hoʻemi ʻia ka nui o ka neʻe ʻana o ka insulin glargine e ka 30% e hoʻohālikelike ʻia me NPH.
I ka wā e hiki mai ana, ke nānā aku nei ke kauka i ke kō, ke ola o ka mea maʻi, kaupaona a hoʻoponopono i ka nui o nā waihona e mālama ai. Ma hope o ʻekolu mau mahina, hiki i ka nānā ʻana o ka lāʻau i kuhikuhi ʻia ke nānā ʻia e ka nānā ʻana o ka hemoglobin glycated.
Nā wikiō wikiō:
Nā kuʻina
Inoa kālepa | ʻO ke ʻano waiwai | Mea hana |
Tujeo | glargine insulin | Kelemani, Sanofi Aventis |
Levemir | detemir insulin | ʻO Denemaka, Novo Nordisk A / S |
Islar | glargine insulin | ʻO India, Biocon Limited PAT "Farmak" |
I Lūkini, ua hoʻohuli paʻa ʻia nā maʻi maʻi āpau i insulin mai Lantus a i Tujeo. Wahi a nā haʻawina, ʻoi aku ka hopena o ka lāʻau hou i ka hoʻomohala ʻana i ka hypoglycemia, akā ma ka hoʻomaʻamaʻa ʻana, ʻōhumu ka hapanui o ka poʻe ma hope o ka hoʻololi ʻana iā Tujeo e lele ikaika ana kā lākou puna, no laila ua koi ʻia lākou e kūʻai i ka Lantus Solostar insulin ma luna o lākou iho.
He lāʻau maikaʻi loa ʻo Levemir, akā he ʻano ikaika ia, ʻoiai ʻo ka lōʻihi o ka hana he 24 mau hola.
ʻAʻole i hālāwai ʻo Aylar i ka insulin, e ʻōlelo nā ʻōlelo i kēia like ʻo Lantus, akā ʻoi aku ka mea maʻalahi o ka mea hana.
Insulin Lantus i ka wā hāpai
ʻAʻole i hoʻokō ʻia nā hoʻopaʻa haʻawina maʻamau ʻo Lantus me nā wahine hāpai. Wahi a nā kumuwaiwai ʻole, ʻaʻole maikaʻi ka hopena o ka lāʻau lapaʻau i ka papa o ka hāpai ʻana a ʻo ke keiki ponoʻī nō ia.
Ua hōʻike ʻia nā hoʻokolohua ma luna o nā holoholona, i ka manawa i hōʻike ʻia ai ka hopena o ka glargine i ole ka hopena i ka hana reproduction.
Hiki i ke ʻōpiopio ʻo Lantus Solostar ke kuhikuhi i ka hihia o ka insulin NPH. Pono ka mālama ʻana o nā makuahine i kā lākou mau momi, no ka mea i ka mea i hoʻomaʻamaʻa mua, hiki ke hoʻemi i ka insulin, a ma ka lua o ke kolamu ʻoi.
Mai makaʻu i ka hānai hānai i kahi pēpē; ʻaʻole i ʻike nā ʻōlelo i hiki iā Lantus ke hoʻokomo i ka waiū umauma.
Pehea e mālama ai
ʻO 3 mau makahiki o ka manaʻo lantus. Pono ʻoe e mālama i kahi wahi pouli e pale ʻia mai ka mālamalama i ke mahana o 2 a 8 tikelē. ʻO ka maʻamau ka nui o ka wahi kūpono ka pahu hau. I kēia hihia, e makaʻala ʻoe e nānā i ke kaima wela, no ka mea ʻae ʻia ka manuahi o ka Lantus insulin!
Mai ka hoʻohana mua ʻana, hiki ke mālama ʻia ka lāʻau lapaʻau no hoʻokahi mahina i kahi wahi pouli i kahi mahana ʻaʻole iʻoi aku ma mua o 25 tikelika (ʻaʻole i loko o ka friji). Mai hoʻohana i ka insulin pau pau.
Kahi e kūʻai aku ai, kūʻai
Noi ʻia ʻo Lantus Solostar i ʻole e ʻae ʻia e ka lāʻau lapaʻau e ka endocrinologist. Akā e kū kekahi i ka mea maʻi hānai i ke kūʻai aku i kēia lāʻau lapaʻau ponoʻī ma kāna mauʻaina. ʻO ke kumukūʻai kiʻekiʻe o ka insulin he 3300 rubles. I Ukraine, hiki ke kūʻai aku iā Lantus no 1200 UAH.
Hoike Mai
Wahi a ka maʻi maʻi, he mea maikaʻi loa ka insulin, e mālama ʻia ko lākou honu i loko o nā palena maʻamau. Eia ka mea a ka poʻe e ʻōlelo ai no Lantus.
ʻO ka hapa nui o nā loiloi maikaʻi wale nō. Wahi a kekahi poʻe ʻo Levemir a ʻo Tresiba ʻoi aku ka maikaʻi no lākou.