ʻO Mikardis Plus e pili ana i nā lāʻau lapaʻau antihypertensive. ʻO ka lāʻau lapaʻa ka hopena hui o ʻelua mau pūhui koʻikoʻi - telmisartan a me kahi diuretic. Mahalo i kēia hui kemu, ua hoʻokō ʻia ka hopena lōʻihi hypotensive, lōʻihi no 6-12 mau hola. ʻO ka hui pūʻana o ka hydrochlorothiazide a me ke telmisartan e hiki ai iā ʻoe ke hoʻololi i ke koko kiʻekiʻe.
ATX
C09DA07.
ʻO Mikardis Plus e pili ana i nā lāʻau lapaʻau antihypertensive.
E hoʻokuʻu i nā palapala a me ka ʻano
Hoʻohana ʻia ka lāʻau lapaʻau i ke ʻano o nā papa, kahi 2 mau pūhui koʻikoʻi - telmisartan a me hydrochlorothiazide.
| Hoʻohui pili | Nā hōʻuluʻulu dosis hiki, mg | ||
| Telmisartan | 80 | 80 | 40 |
| Diuretic | 12,5 | 25 | 12,5 |
| Nā peni kala | Hoʻopili ʻia kekahi ʻulaʻula me ka ulaula | Kūʻai me nā komo o ka melemele | Kāpena |
E like me nā mea hoʻohui hou e hoʻomaikaʻi i ka wikiwiki a me ka hoʻopiha ʻana i ke kūoʻi ʻana o nā:
- ʻōpala palaoa;
- waiū waiū;
- mikulamulamina selulose;
- sodium hydroxide;
- wa hao hoʻoneʻe;
- povidone;
- sorbitol;
- Nā meglumine.
Hana ʻia nā papa ma ke oval me ka uhi biconvex. ʻAʻole kahi mea antihypertensive e hoʻomaʻamaʻa ʻia ma ke ʻano o kahi pakanō, gel, a i ʻole nā makua.
Hoʻohana ʻia ka lāʻau lapaʻau i ke ʻano o nā papa, kahi 2 mau pūhui koʻikoʻi - telmisartan a me hydrochlorothiazide.
Ka hana lāʻau lapaʻau
He hopena antihypertensive o Telmisartan ma muli o ka paa ʻana i ka receptors angiotensin II. Me ka hoʻokumuʻana o ia paʻakikī, e hoʻoneʻe ka mea hana a me ka hana i nā kaepae vasoconstrictor a hōʻemi i ka kaohi ʻana o ka ald testosterone i loko o ke koko. ʻAʻole hiki i ke Angiotensin II ke kumu i ka haki ʻana o ka bradykinin, no ka mea, ua pāpā ʻia ʻo ia e ka telmisartan. No laila, hoʻomau ka synthes o ka bradykinin - ʻo kahi vasodilator e hoʻonui i ka lumen i ke kahe koko.
Hoʻonui ka hopena vasodilating i ka hydrochlorothiazide ma muli o ka hopena diuretic. Hoʻokomo kahi diuretic thiazide e hōʻemi i ke koko kiʻekiʻe me ka hypertension koʻikoʻi. Me ka hoʻohana mau ʻana, hoʻemi ʻia ka hydrochlorothiazide i ka hiki ʻana mai o ke kūkulu ʻana i nā ala poloka a me ka make ma kēia mau maʻi.
Loaʻa ka hopena therapeutic kiʻekiʻe loa i loko o nā hola 3.5-4.
Noho paʻa nā ʻōhumu koko ma nā lā 6-12 mau hola.
Lapaʻau lāʻau
Ma hope o ka hoʻohana ʻana, ua wāwahi ʻia ka papa e ka enzymes intestinal.
Ke hoʻokuʻi nei ʻo ia, ʻo nā hana ikaika o ka lāʻau Mikardis Plus e hoʻopili koke ʻia i ka pā o ka ʻili liʻiliʻi.
Ke hoʻokuʻu ʻia nei, e hoʻopili koke ʻia nā mea ikaika i loko o ka pā o ka pā liʻiliʻi a komo i ke kahe koko. Ma ka lōlani ʻōnaehana, ka telmisartan a me ka hydrochlorothiazide e hele i kahi kaila o ka lōʻihi ma 30-90 mau minuke. ʻO ka bioavailability o ka lua aniotistin antagonist receptor hiki i ka 50%, hydrochlorothiazide i loko o 60%. Hoʻololi ʻia nā mea kūlohelohe i nā hepatocytes.
ʻO ka hapalua ola he 6 mau hola. Ke waiho nei ʻo Telmisartan i ke kino i ke ʻano o nā huahana decay hiki ʻole ke hoʻomau ʻia ma o ka urinary system ma o 60-70%. Hoʻololi ʻia ka Hydrochlorothiazide i ka loli i ka 95%.
Nā hōʻailona no ka hoʻohana ʻana
Pono ka lāʻau pono e hoʻemi i ke koko kiʻekiʻe me ka hoʻoikaika ʻole o ka telmirsartan therapy e like me ka monotherapy.
Nā Hoʻohui
ʻAʻole mālama ʻia ka lāʻau lapaʻau no ka mālama ʻana o nā mea maʻi me ka hoʻomanawanui ʻole ʻana i nā mea ikaika a me nā mea hoʻohui hou o Mikardis Plus. Ke hana nei kēia mau kaʻina hana holomua i ke ʻano he contraindication no ke hoʻohana ʻana:
- pēpē bile halihali me ka cholestasis concomitant;
- hana pili maʻi;
- ka helu ʻoki ʻana i ka hana o ke keiki;
- mellitus maʻi ikaika;
- hoʻonui mahuahua o ka calcium a me nā haʻahaʻa haʻahaʻa o ka paʻakai i ke kino;
- hereditary form of intolerance to galactose, fructose, lactose
Ke papa ʻia nei ka lāʻau lapaʻau no ka hoʻohana ʻana i nā mea maʻi me ka maikaʻi ʻole o ka maʻi a me ka maʻi diabetes me ka hoʻohana pono ʻana o Aliskiren.
Pehea e lawe ai
Me kahi hiʻona maʻalahi o ka pathology, ua lawe ʻia ʻo Mikardis i ka manawa 1 i kēlā me kēia lā, me ka ʻaihue ʻole. ʻAʻole pili ke kō i ka ʻai me ka pākuʻi o Mikardis.
Me kahi hiʻona maʻalahi o ka pathology, ua lawe ʻia ʻo Mikardis i ka manawa 1 i kēlā me kēia lā, me ka ʻaihue ʻole.
No nā pākeke
Hāʻawi ʻia ka pākana maʻamau i kēlā me kēia lā no ka pā hoʻokahi o kahi papa kīwī me 80 mg o telmisartan a me 12.5 mg o hydrochlorothiazide. Inā lawa ʻole ka hopena hypotensive, akā me ka hoʻomanawanui maikaʻi, pono ʻoe e inu i nā papa he 80 mg o ka telmisartan a me 25 mg o ka hydrochlorothiazide.
ʻO ka hopena hypotensive kiʻekiʻe e nānā ʻia ka mau mahina ma hope o ka hoʻomaka ʻana o ka lāʻau conservative.
ʻO nā maʻi me nā maʻi maʻi hypertension e pono e lawe i 2 papa i kēlā me kēia lā. Ma kēia hihia, ua kuhikuhi ʻia ka nui o ka hydrochlorothiazide e ke kahu hele ʻana ma muli o ka ʻikepili hoʻopaʻa o ka mea maʻi.
Koho ʻo Mikardis Plus no nā keiki
Hoʻopilikia ka lāʻau lapaʻau no ka hoʻohana ʻana a hiki i ka makahiki 18 ma muli o ka hemahema o ka ʻike ʻana i ka hopena o nā mea ikaika i ka hoʻomohala ʻana o ke kanaka i ke kula mua a me ka wā ʻōpiopio.
ʻO ka lāʻau ʻo Mikardis Plus e contraindicated no ka hoʻohana ʻana a hiki i ka 18 mau makahiki.
Lawe i ka lāʻau lapaʻau no ka maʻi maʻi maʻi
ʻO nā maʻi me ka maʻi maʻi e hoʻomau mau i kā lākou kiʻekiʻe pae serum glucose. I ka wā o ka maʻi me Mikardis, aia ka hopena o ka hypoglycemia ma muli o ka hopena diuretic o ka hydrochlorothiazide.
Nā hopena hopena
Hōʻike ʻia nā hopena maikaʻiʻole ma muli o ke ʻano kūpono i koho ʻia a hoʻokaʻawale ʻia i ka hapa nui e nā maʻi maʻamau.
ʻŌpala Gastrointestinal
Aia kahi hoʻohālikelike o ka hoʻomohala ʻana i nā laʻi o ka ʻōpū a me ka gastritis. Loaʻa kekahi mau maʻi i ka ʻeha epigastric, constipation, ʻeha ʻana, a me ka ʻuwelu.
Hematopoietic mau hui
ʻO ka pae o nā mea i hoʻokumu ʻia o ka plasma koko i hoʻemi ʻia.
Pūnaehana pīhoihoi waena
Me kahi kaumaha o ka pūnaehana neʻe i waena a me ka hoʻomohala ʻana i ka pilikia o ka noʻonoʻo i kekahi kanaka, ua loli ke ʻano hoʻohālike - i kahi noho kaumaha, ʻike i ke ʻano hopohopo.
ʻO ka ʻeha, ka ʻeha, ka paresthesia, ka nāwaliwali laulā, nā pilikia hiamoe.
Mai ka pūnaehana urinary
I nā mea maʻi me ka hala ʻana o ka urine i waho (me ka hyperplasia benign prostatic, prostatitis), mālama i ka urination, ʻokoʻa ka pale ʻana. I nā pilikia liʻiliʻi, loaʻa i ka hoʻonui ʻana i ka plasma ʻaila o ka uric acid.
Mai ka papa huhū
E kūʻē i ke kūmole o ka angioedema, hiki ke loaʻa ka hiʻohiʻona ʻana o ke ea kikowaena, ka hiki ke nānā ʻia o ka bronchospasm.
Mai ka ʻōnaehana musculoskeletal
Hōʻike nā hopena maikaʻi ʻole i ka musculoskeletal system i ka hiʻohiʻona o nā cramp ma nā ʻāʻī o ke keiki bipi, ka ʻeha i nā ʻōpū a me nā ʻili, a ma hope loa.
Allergies
Ma ke hana ma hope o ka kūʻai ʻana, ua hōʻike ʻia nā hihia o ka nānā ʻana o ka systemus lupus erythematosus, angioedema, a me nā hopena ʻili.
Nā ʻōlelo kikoʻī
Ke hoʻomau nei ka lāʻau i ka hopena vasodilating. Me ka hoʻohaʻahaʻa haʻahaʻa o ke kahe koko (BCC), e hoʻoneʻemu ʻia ka nui o ke kahe koko, no ka mea, ʻaʻole lawa ka wai a me ka nui o ke kahe koko no ka neʻe maʻamau. Ma muli o ka hiki ke hoʻomohala ʻana i ka hypotension hōʻailona, nā maʻi ma ka papa me ka liʻiliʻi o ka paʻakai o ka paʻakai, me ka wā maʻamau a me ka hoʻopuka, i ka wā e lawe ai i ka diuretics ma mua o ka lawe ʻana iā Mikardis Plus, pono ia e hoʻihoʻi i ka BCC.
I kekahi mau hihia, hoʻokō ka lāʻau i ka hopena o ka ʻili.
ʻO ka lawe ʻana i kahi mana hypotensive hiki ke alakaʻi i ka hoʻomohala ʻana o ka maʻi cerebrovascular a i ʻole hōʻeha ka naʻau ma nā mea maʻi me ischemia muscle cardiac.
Hiki i Hydrochlorothiazide ke hoʻonāukiuki i kahi ʻano o ke myopathy a i ʻole ka helehelena o ka glaucoma o ke kihi. ʻO ka hōʻailona mua o nā ʻōnaehana pathological he hōʻeha ʻeha ma nā maka, ʻaʻole ia e haʻalele no kahi manawa lōʻihi. Inā loaʻa iā ʻoe i ka ʻeha a me ka hoʻohaʻahaʻa i ka puʻuwai ʻike, pono ʻoe e haʻalele koke e lawe iā Mikardis Plus.
Hoʻolaha ka waipuna
I ka wā ʻohi antihypertensive, ʻaʻole ia e inu ʻia e inu i nā mea inu wai.
Hiki i ka Ethyl alkohol ke hoʻonāwaliwali i ka hopena antihypertensive, hoʻoikaika i ka hopena diuretic o ka hydrochlorothiazide a kumu i ka spasm o ka endothelium vascular i nā moku peripheral.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
ʻAʻole pili ka lāʻau lapaʻau i ka hana o ke ʻōnaehana kūlohelohe a me nā mākaʻi maikaʻi. I ka manawa like, pono ia e makaʻala i nā hana akaʻa ke hana nei me nā pūnaehana paʻakikī a i ke kaʻa ʻana aku i kahi kaʻa, no ka mea hiki ke nalowale i ka ʻike, ke ʻano o nā hopena ʻaoʻao (ke kaumaha, nā dizziness). Hiki i nā hopena maikaʻi ke hoʻoemi i ka ʻike o ka nānā a me ka wikiwiki o ka hopena psychomotor pono no ka hoʻokuke.
Hoʻohana i ka wā hāpai a me ka lactation
ʻO nā wahine i ka wā hāpai ua pāpā ʻia i ka lawe ʻana iā Mikardis ma muli o ka hopena hiki i ka nui o nā kāne ke hānau.
Ma ke kaʻina o ka hoʻolālā embryonic, hiki i ka hoʻopau ʻana i nā ʻōkene cardiovascular a me nā urinary.
Ke hoʻokomo nei i ka lāʻau lapaʻau lāʻau, pono ia e hōʻoki i ka umauma.
Ke hoʻokomo nei i ka lāʻau lapaʻau lāʻau, pono ʻo Mikardis Plus e ho'ōki i ka umauma.
Ke keu
Me ka pākahi hoʻokahi o kahi kiʻekiʻe kiʻekiʻe ma mua o ke ʻano i ʻōlelo ʻia ʻia, ʻo ka loaʻa ʻana o ka hōʻailona o ka hōʻaiʻe o ka overdose. Nā hōʻailona hōʻailona i:
- ka hoʻohaʻahaʻa ʻana i ke koko;
- hoʻonui a hōʻemi paha i ka puʻuwai naʻau;
- ninini
- pupule o ka ike;
- hiamoe
I kekahi mau hihia, ulu kahi hopena diuretic ikaika. Ma muli o ka nalowale o ka nui o nā nui o ka wai, e hoʻomaʻamaʻa ke kino i ka dehydration, a me ka emi o ka pae o nā electrolytes. ʻO ke hiʻohiʻona o ka hypoglycemia e hoʻoluhi i ka pīhoihoi uaua a hoʻomaikaʻi paha i ka arrhythmia.
Ma kahi o kahi overdose, pono ka mea maʻi i ka mālama maʻi. I nā kūlana paʻa, ua kau ʻia ka mālama ʻana i ka hoʻopau ʻana i nā hōʻailona maikaʻi ʻole a me ka hoʻokaʻawale i ke kaulike wai-electrolyte.
Hoʻopili pū me nā lāʻau ʻē aʻe
Me ka hoʻohana like ʻana o Mikardis me nā mea hoʻohana e pili ana i ka lithium, hiki ke loaʻa kahi hoʻololi no ka hoʻololi ʻana ma ka serum lithium.
I kēia mea, hoʻokaʻawale ka renal cleitce o ka lithium a hoʻomohala a hoʻomohala i ke ʻano, ʻo ia ke kumu ke kuhikuhi ʻole nei i ka kuhikuhi ʻana i ka therapy kuʻuna me ka lithium a me ka lāʻau hypotensive. ʻIke ʻia kahi kūlana like me ka hoʻomākaukau ʻana o ka potassium.
ʻO nā lāʻau lapaʻau e hōʻemi ana i ka manaʻo o ka potassium ma loko o ke kaila koko e kōkua i ka hoʻomohala ʻana o ka hypokalemia. Me kā lākou hoʻokūkū pinepine me Mikardis, pono ia e kāohi i ke kiʻekiʻe o ka paʻakai ma ke kino.
ʻO nā maʻi anti-inflammatory nonsteroidal (NSAID) hiki i ka mea hoʻomohala i ka hoʻomohalaʻana o ka hoʻomoʻewaʻina, ʻo ia ke kumu i nui ai ka nui o ka poʻe o ka makahiki he 50 mau makahiki. ʻO ka NSAID e hōʻemi i ka hopena therapeutic o ka diuretics a me nā lāʻau antihypertensive.
ʻO nā lāʻau kanu anticholinergic me Mikardis Plus e hōʻemi i ka neʻe o nā māla maʻa o ka gastrointestinal tract.
ʻO nā kumu o ka waikawa barbituric a me nā antipsychotics e hoʻonāukiuki i ka hoʻokumu ʻana o ka hypotension orthostatic me ka hala o ka noʻonoʻo.
Hoʻonui ka Metformin i ka hopena o ka acidact lactic i ka wā e hoʻopili ana me ka hydrochlorothiazide.
ʻO nā lāʻau lapaʻau antihypertensive e hui pū me Mikardis he synergistic - hoʻonui ʻia ka hopena hypotensive i nā manawa he nui i hilinaʻi ʻia o nā hiʻohiʻona pilikino o ka mea maʻi.
Hoʻololi nā kumu resolestoli i ka helu o ka hoʻopuka ʻana o ka hydrochlorothiazide. Hoʻonui ka hua lāʻau Anticholinergic i ka bioavailability o ka diuretics thiazide, no ka mea ke iho nei ka hōʻemi ʻana i nā peristalsis o nā māʻule o ka ʻalā o ka ʻeha o ka gastrointestinal.
Mea hana
Beringer Ingelheim Ellas A.E., Koropi, Helene.
Mikardis Plus Analogs
I ka hiki ʻole o ka hopena hypotensive, hiki ke hoʻololi ʻia iā Mikardis me kekahi o nā mea hoʻohālike:
- Eia;
- Prirator;
- Lozap Plus;
- Telmisartan;
- Telmisartan Richter;
- Telmista.
Waihue huaʻōlelo waiho nā huaʻōlelo
Hiki ke kūʻai lilo ʻia ka lāʻau lapaʻau ma o ka lāʻau lapaʻau.
Kūʻai
Ka loli kumukūʻai o nā papa ma 1074 a 1100 mau rubles.
He kūlana paʻa kākoi ʻo Mikardis Plus
Manaʻo ʻia e mālama i ka waihona antihypertensive ma kahi e kaawale ana mai ka radiation ultraviolet ma ke mahana o + 8 ... + 25 ° C.
ʻO ka lā kau
3 mau makahiki
Hoike e pili ana iā Mikardis Plus
Wahi a nā poʻe cardiologists a me nā mea maʻi, he maikaʻi ʻo Mikardis i ka hakakā ʻana me ka hypertension.
Cardiologists
Elena Bolshakova, cardiologist, Moscow
Ua hana wau i kahi haʻawina ma ke ʻano he dissertation i ka hopena o ka lāʻau lapaʻau, no laila hiki iaʻu keʻike wiwoʻole e pili ana i ka hopena o Mikardis. Ke kōkua nei ka lāʻau lapaʻau e hoʻopaʻa i ka pīkoi polū o ka papa liʻiliʻi a hōʻemi i ka wikiwiki o ka hoʻoulu ʻana o nā nalu cardiac, kahi e hoʻonāukiuki ai i ka hoʻomohala ʻana o nā maʻi cardiovascular. Loaʻa ka lāʻau lapaʻau i nā ʻōpio a no nā poʻeʻelemakule. ʻO nā hopena ʻokoʻa e koi ai i ka hiki ke hoʻololi ʻia, ma ka hoʻomaʻamaʻa ʻole ʻaʻole i hālāwai. ʻAʻole pili ka lāʻau lapaʻau i ka ʻike.
Sergey Mukhin, cardiologist, Tomsk
Manaʻo wau he mea kūpono ka lāʻau lapaʻau e hōʻemi i ke koko kiʻekiʻe. Ke kiʻi ʻia i ka lā hoʻokahi, e hoʻomau ka hopena therapeutic i hoʻokahi lā. Ua kiʻekiʻe ke kumukūʻai. ʻO kahi papa nui o nā contraindications. Akā maikaʻi ka lāʻau lapaʻau no nā maʻi maʻi type 2, mau maʻi maʻi coronary. Hāʻawi ʻia ka hoʻohana ʻana i nā maʻi me ka puʻuwai naʻau ʻole. Loaʻa nā maʻi kūloko i nā maʻi kuʻuna.
Hiki ke hoʻololi ʻia ʻo Mikardis Plus me Pritor, ka mea i mālama ʻia ma kahi wahi i kaawale ʻia mai ka radiation ultraviolet i ke mahana o + 8 ... + 25 ° C.
ʻO nā maʻi maʻi
ʻO Dmitry Gavriilov, 27 makahiki, Vladivostok
Hoomaka ka hypertension arterial, ma muli o ke ahiahi aia ka pōloli maikaʻi, ka nele o ka ea, a hoʻomohala ʻia ka arrhythmia. Ua kuhikuhi nā Kauka i nā papa Mikardis. Ua hoʻomaka ka lāʻau lapaʻau e hana i ka lā mua. 3 mau hola ma hope o ka lawe ʻana i nā papa, ua hoʻomau ʻia ke kaumaha no nā hola 20 i hala aʻe. He mea nui e lawe i nā lāʻau ʻē aʻe e kōkua e mālama i kēia hopena. Ke kono aku nei au e kamaʻilio pū me kāu kauka e pili ana i ka hoʻokaʻawale i ke ʻano lāʻau me nā mea ʻona paʻakikī.
Alexandra Matveeva, 45 makahiki, St.
Hoʻopiʻi me ka hypertension ma hope o ka hoʻomaʻamaʻa ʻana i ka papa thyroid. Ua kuhikuhi ka kolohe iā MikardisPlus i nā papa o ka hana lōʻihi. Makemake wau i ka lāʻau lapaʻau, hoʻohaʻahaʻa iki i ke koko. ʻAʻole hopena ka hopena o ka lāʻau i ke kino a ʻaʻole e hoʻonāukiuki i ka hopena, anaphylactic ʻano. Ua hōʻea ka paheʻe i 130/80 a noho i kēia kiʻekiʻe. Ke kuhikuhi aku nei wau iā ʻoe e hana i nā wā i hala o 2 mau wiki i ka wā e lawe ai i ka lāʻau lapaʻau.
