Alanine aminotransferase a me aspartate aminotransferase he protina kikoʻī a loaʻa wale nō ia i loko o nā pona o nā kino o nā kino o nā kino. E hele mai kēia mau hana i ka hihia wale nō e hoʻomālamalama ai i nā ʻōnaehana cell.
Nā ʻāpana like ʻole o nā ʻāpana like ʻole o kēia mau māhele. No laila, ʻo ka hoʻololi ʻana i kekahi o kēia mau pūmū e hōʻike i ka loaʻa ʻana o nā maʻi i kekahi mau kino.
ʻO ALaT kahi enzyme i loaʻa mua i nā ʻiʻo o ka pūpū, nā uaua a me nā pancreas. Ke kū ʻia ka pōʻino, piʻi mālie ka pae o kēia mahele, kahi e hōʻike ai i ka luku ʻia o kēia mau kiko.
ʻO ASaT kahi enzyme e loaʻa ana i kahi nui:
- nā ate
- māhelo
- mea hoʻopili iwi.
ʻO kahi ʻāpana o ke kiko, nā ʻōpū a me nā pancreas, ua paʻa kēia mea i loko o kahi liʻiliʻi.
ʻO ka hoʻonui ʻana i ka neʻe o ka ASaT hiki ke hōʻike i ka kuhi hewa i ka loko o nā pakanō a me nā kiko.
Alanine aminotransferase a aspartate aminotransferase he mau enzyme i loko o nā pūpuna a komo i loko o ka hana ʻaila amino intracellular. ʻO ka hoʻonuiʻana i kēia mau māhele e hōʻike ana i ke kau ʻana o kahi mea maʻi maʻi i ka hana o kekahi ʻuhane.
No ka laʻana, kahi nui koʻikoʻi o ALT e hōʻike i ka hoʻomohala ʻana o ka pancreatitis i nā hana kūleʻa a i ʻole nā mana koʻikoʻi.
Ma ka ʻike o ka hoʻoemi ʻana i ka hoʻoneʻe ʻana o kēia mau ʻano o ka hoʻokaʻawale ʻana, hiki iā mākou ke manaʻo i ka hoʻomohala ʻana o nā ʻatikala palolo nui e like me, e laʻa, cirrhosis
Ke hilinaʻi nei o ka neʻe o kēia mau hoʻoili i ke kūlana o nā ʻāpana kūloko a me ka hiki ʻana o ka pōʻino o ka kino e hiki ai i kēia kiana ke hoʻohana i nā maʻi o ka maʻi.
ALT maʻamau a me AST
Hoʻoholo ʻia ka hoʻonā ʻana o kēia mau enzyme e ka nānā ʻana biochemical.
I mea e loaʻa ai nā hopena loiloi me kahi kiʻekiʻe o ka hilinaʻi, pono ka biomaterial no ka ʻimi noiʻi ʻana i kakahiaka nui a ma kahi ʻōpū ʻole. A manaʻo ʻia ʻaʻole e ʻai i ka meaʻai ma mua o ka hāʻawi ʻana i ke koko no ka liʻiliʻi 8 mau hola.
Lawe ʻia ka hana Laboratory mai kahi vein.
I kahi kūlana maʻamau, ʻokoʻa ka ʻike o kēia mau enzyme i ke koko o ke kanaka ma muli o ka wahine.
No nā wahine, ʻike ʻia ke kiʻekiʻe o ka pae, ʻaʻole i keu i nā hōʻailona ʻelua i ka waiwai o 31 IU / l. No ka ʻāpana kāne o ka heluna kanaka, ʻike nā manamana maʻamau o ka alanine aminotransferase no ke ʻano he 45 IU / L, a no ka aspartate aminotransferase, ke ʻano maʻamau ka hanohano ma mua o 47 IU / L.
I ke wā ʻōpiopio, hiki i kēia hōʻailona ke hoʻololi i ka 50 a i nā ʻāpana 140 a me ka l
Hiki i nā ʻōmaʻomaʻo maʻamau o nā ʻikepili o kēia mau enehana ke ʻano ma muli o nā mea hana i hoʻohana ʻia no ka ka nānā ʻana, no laila, he kauka i ʻike pū i nā ʻano o ka lāʻau o ka mea i hana ʻia ai ke ʻano loiloi.
Nā kumu o Alanine Aminotransferase pae
ʻO ke kumuhana kiʻekiʻe i ke kahe o ke alanine aminotransferase e hōʻike ana i ka loaʻa ʻana o nā maʻi o ia mau kino i kahi o kēia māhele i loko o ka nui.
Aia i ka pae o ke neʻe mai ka maʻa maʻamau, hiki i ke kauka ke manaʻo nei ʻaʻole wale ka hele ʻana o kekahi ʻano maʻi, akā ʻo kāna ʻano, a me ke ʻano o ka hoʻomohala ʻana.
Aia paha he mau kumu no ka hoʻonui ʻana o ka enzyme.
Ke kumu nei ke kumu o ka:
- ʻO ka hepatitis a me kekahi mau maʻi e like me ka cirrhosis, hepatosis momona a me nā maʻi. Ke hele nei i kekahi ʻano o ka hepatitis, e hoʻopau ʻia ka ʻōpala o ke kino, e hoʻonāukiuki i ka ulu o ALT. Me ka ulu ʻana o kēia mākaukau, ua hōʻike ʻia ka hepatitis e ka piʻi ʻana o ka bilirubin. Hoʻomoe pinepine ʻia ka nui o ka ALT i ke kahawai koko ma mua o ka nānā ʻana o nā hōʻailona mua o ka maʻi. ʻO ka pae o ka hoʻonui i ka paʻa o ke alanine aminotransferase e like me ka nui o ka maʻi.
- Pākuʻi ʻia ʻo Myocardial infarction e pili ana i ka make a me ka luku ʻana o ka ʻōpū o ka naʻau, ka mea e hoʻonāuki i ka hoʻokuʻu ana i nā alanine aminotransferase a me AST. Me ka puʻuwai pu, ʻike ʻia kahi hoʻonui manawa like i nā hōʻailona ʻelua.
- ʻO ka loaʻa ʻana o ka hōʻeha nui me nā hanaʻino o nā ʻōpiha.
- Ke kiʻi ʻana no nā lā ʻana.
- ʻO ka hoʻomohala ʻana o ka maʻi pancrekitis, ʻo ia ka mumū i ka kiko pancreatic.
ʻO nā kumu āpau o ka hoʻonui ʻia ʻana o ka ALT e hōʻike ana i ka loaʻa ʻana o nā ʻōnaehana pathological i loko o nā kino i loaʻa i ka nui o kēia enzyme a me ka hoʻopili ʻia ʻana o nā aʻa.
Ke hoʻonui pinepine nei i loko o ka alanine aminotransferase ma mua o ka hōʻailona o ka hōʻailona ʻano mua o ka hoʻomohala ʻana o ka pathology.
ʻO nā kumu o ka kiʻekiʻe aspartate aminotransferase kiʻekiʻe
ʻO ka hoʻonui ʻana o ka AST i ke kahe koko e hōʻike i ka hiki ʻana mai o nā maʻi o ka puʻuwai, nā ʻāpana a me nā pancreas a me ka hoʻomohala ʻana i nā pathologies i ke hana ʻana o kēia mau mea.
ʻO ka hoʻonui pinepine ʻana o ka ASaT hiki ke hōʻike i ka luku ʻia o nā kino o nā kino i loaʻa ka nui o kēia ʻano transferase.
Aia he nui nā pono e pili ana i ka hoʻonui ʻana i ka hoʻoili ʻana o AST.
ʻO nā mea nui ka mea penei:
- ʻO ka hoʻomohala ʻana o ka myocardial infarction ka mea maʻamau ke kumu o ka hoʻonui ʻana i ka nui o ka aspartate aminotransferase. Me ka puʻuwai puʻuwai, he nui nui ka piʻi ʻana o AST ʻoiai ʻaʻole e hoʻonui nui ʻana i ka nui o ALT.
- ʻO ka piʻi a me ka holomua o myocarditis a me ka maʻi naʻau rheumatic.
- ʻO nā ala āpau o ka maʻi - hepatitis viral a me ka hepatitis o ke kūleʻa a me nā lāʻau lapaʻau, cirrhosis a me nā maʻi maʻi. Ke alakaʻi nei kēia mau kūlana i ka piʻi like o nā AST a me ALT.
- ʻO ka loaʻa ʻana i kahi hōʻeha nui a ke kanaka.
- ʻO ka holomua ʻana o ka maʻi pancreatitis a me ke ʻano.
Ke unuhi nei i ka ʻikepili i loaʻa i ka wā o ka loiloi biochemical o ke koko, pono ia e noʻonoʻo i nāʻokoʻa o ka wahine.
ALT a me AST no ka ʻike ʻana o ka pancreatitis
Pehea e lawe ʻia ai ka nānā ʻana o ka nānā ʻana o ka hana biochemical i ka wā noiʻi ma ALT a me AST?
ALT a me AST no ka maʻi pancreatitis e loaʻa mau i nā helu overestimated.
I ka loaʻa ʻana o ka aminotransferase aspartate i ke koko, pono ia e hoʻoholo i ka nui o kēia parameter e kū aʻe nei mai ka maʻamau. ʻO ka maʻamau, aspartate aminotransferase i kahi wahine ʻaʻole iʻoi aku i kahi 31 PIECES / l, a me nā kāne - ʻaʻoleʻoi aku ma mua o 37 PIECES.
I ka hihia o ka maʻi nui o ka maʻi, e ulu ana ka ulu o ka aspartate aminotransferase i nā manawa he nui, ʻo ka manawa pinepine ka manaʻo e hoʻonui i ka hoʻonui ʻana o 2-5 mau manawa. Eia kekahi, me ka pancreatitis, a me ka ulu ʻana o ka aspartate aminotransferase, ka hoʻomaka ʻana o nā hōʻailona hōʻeha e mālama ʻia i ka pōʻai, hōʻoki ʻia ke kaumaha o ke kino a me ka hōʻeha mau pinepine i ke kanaka. ʻAʻole kū ʻia ke ʻano o ka hoʻokuʻi me ka pancreatitis.
Ke piʻi nui nei ka nui o ka ALT i ka pancreatitis, a me kēlā hoʻonui e hiki ke hele pū me ka hoʻonui i ka alanine aminotransferase e 6-10 mau manawa.
Ma mua o ka hoʻokō ʻana i ka nānā ʻana o ka biochemical no ka hoʻoili ʻana, ʻaʻole ia he mea i ʻai no ka liʻiliʻi 8 mau hola.
Eia kekahi, ʻaʻole pono e hoʻohana i nā lāʻau lapaʻau e hiki ke hoʻonui i ka ʻike o kēia mau ʻano o nā enzyme. ʻAʻole e hana i ka hoʻoikaika kino koʻikoʻi ma mua o ka hāʻawi ʻana i ke koko no ka nānā ʻana.
ʻO ka pancreatitis kahi maʻi e hele pū me ka mea maʻi i ke ola holoʻokoʻa.
I mea no ka papa o ka pancreatitis ʻaʻole i ukali ʻia e nā wā o ka hōʻino nui, ua ʻōlelo ʻia nā mea maʻi e hāʻawi pinepine i ke koko no nā haʻawina biochemical.
Eia kekahi, pono nā poʻe maʻi e hana maʻamau a e like me nā ʻōlelo a ke kauka komo e mālama i nā lāʻau lapaʻau e pani ai i ka holomua o ka maʻi a me nā enzyme kūikawā i hoʻolālā ʻia e hōʻemi i ka hana ma luna o ka pancreas.
Eia nō naʻe, i ke ʻano o ka mālama ʻana, pono e hoʻohana ʻia nā lāʻau lapaʻau, ka hana e kuhikuhi ana i ka detoxification a me ka hoʻopauʻana i nā huahana e ala mai ana i ka luku ʻia ʻana o ka maʻi pancreatic.
Ua hōʻike ʻia kahi hōʻike koko no ALT a me AST i ke wikiō ma kēia ʻatikala.
